Page last updated: 2024-11-04

succinylcholine and Cough

succinylcholine has been researched along with Cough in 14 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"The purpose of the study was to determine the effect of nondepolarizing muscle relaxants and waiting time on muscle fasciculations after succinylcholine in anaesthetized patients."7.69Waiting time after non-depolarizing relaxants alter muscle fasciculation response to succinylcholine. ( Patterson, L; Pinchak, AC; Shepard, LS; Smith, CE, 1994)
"The purpose of the study was to determine the effect of nondepolarizing muscle relaxants and waiting time on muscle fasciculations after succinylcholine in anaesthetized patients."3.69Waiting time after non-depolarizing relaxants alter muscle fasciculation response to succinylcholine. ( Patterson, L; Pinchak, AC; Shepard, LS; Smith, CE, 1994)
"Propofol was followed immediately by either rocuronium 0."2.69A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol. ( Andrews, JI; Kumar, N; Olkkola, KT; Roest, GJ; van den Brom, RH; Wright, PM, 1999)
"Alfentanil 15 mu g/kg was not statistically significantly different from saline (P = 0."2.68Intubation without muscle relaxant: an alternative technique for rapid tracheal intubation. ( Teoh, GS; Wong, AK, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's7 (50.00)18.2507
2000's4 (28.57)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liao, AH1
Lin, YC1
Bai, CH1
Chen, CY1
de Almeida, MC1
Pederneiras, SG1
Chiaroni, S1
de Souza, L1
Locks, GF1
Betemariam, K1
Soodan, A1
Pawar, D1
Subramanium, R1
Ortiz-Gómez, JR1
Carrascosa, F1
Pérez-Cajaraville, JJ1
Percaz-Bados, JA1
Añez, C1
Zemenick, RB1
Pinchak, AC1
Smith, CE1
Shepard, LS1
Patterson, L1
Koh, KF1
Chen, FG1
Steyn, MP1
Quinn, AM1
Gillespie, JA1
Miller, DC1
Best, CJ1
Morton, NS1
Wong, AK1
Teoh, GS1
Andrews, JI1
Kumar, N1
van den Brom, RH1
Olkkola, KT1
Roest, GJ1
Wright, PM1
Tammisto, T1
Mattila, MJ1
Silverman, SM1
Culling, RD1
Middaugh, RE1
Tonsa, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction: Dosing According to Elapsed Time for Two Age Groups,IRB-HSR# 13666[NCT01150838]Phase 4106 participants (Actual)Interventional2008-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Estimated Propofol Doses Producing 50% Excellent Intubation Conditions

"Logistic regression utilized to measure the amount of propofol to obtain 50% excellent intubation conditions for each age/time group.~The quality of tracheal intubation will be graded according to the Steyn modification of the Helbo-Hansen scoring system for tracheal intubation, which includes evaluation of ease of laryngoscopy, position of the vocal cords, coughing, jaw relaxation and movement of limbs, each evaluated on a 1-4 scale, with 1 being the best possible condition and 4 the worst. The intubation conditions will be classified as either excellent or not-excellent. Excellent will be defined as a total score of 5, a score of 1 for each category, and not-excellent will be a total score of 6-20, meaning a score of >1 in any category. While the outcome measure of each intubation is excellent or not excellent, the overall outcome being generated is the amount of propofol in mg/kg required for 50% excellent intubation score." (NCT01150838)
Timeframe: Amount of time it takes to intubate each patient; approximate time is 15-45 seconds

Interventionmg/kg (Mean)
Age 1-6 Years, Time 2-4 Minutes of Sevoflurane Until Propofol Administration1.48
Age 1-6 Years, Time 4-6 Minutes of Sevoflurane Until Propofol Administration0.00
Age 1-6 Years, Time 6-8 Minutes of Sevoflurane Until Propofol Administration0.07
Age 6-11 Years, Time 2-4 Minutes of Sevoflurane Until Propofol Administration2.35
Age 6-11 Years, Time 4-6 Minutes of Sevoflurane Until Propofol Administration2.33

Reviews

1 review available for succinylcholine and Cough

ArticleYear
Optimal dose of succinylcholine for laryngeal mask airway insertion: systematic review, meta-analysis and metaregression of randomised control trials.
    BMJ open, 2017, Aug-04, Volume: 7, Issue:8

    Topics: Cough; Dose-Response Relationship, Drug; Gagging; Humans; Intubation, Intratracheal; Laryngeal Masks

2017

Trials

9 trials available for succinylcholine and Cough

ArticleYear
[Evaluation of tracheal intubation conditions in morbidly obese patients: a comparison of succinylcholine and rocuronium].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:1

    Topics: Adult; Androstanols; Body Weight; Cough; Diaphragm; Dose-Response Relationship, Drug; Female; Humans

2009
Anesthesia for removal of inhaled foreign bodies in children.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:11

    Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Gas Analysis; Bronchos

2004
Comparative study of intubating conditions at the first minute with suxamethonium, rocuronium and different priming techniques of rocuronium.
    European journal of anaesthesiology, 2005, Volume: 22, Issue:4

    Topics: Adjuvants, Anesthesia; Adult; Aged; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Atr

2005
Rapid tracheal intubation with atracurium: the timing principle.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:8

    Topics: Adult; Anesthesia, Intravenous; Atracurium; Blood Pressure; Cough; Female; Fentanyl; Flushing; Heart

1994
Tracheal intubation without neuromuscular block in children.
    British journal of anaesthesia, 1994, Volume: 72, Issue:4

    Topics: Adenoidectomy; Adolescent; Alfentanil; Blood Pressure; Child; Child, Preschool; Cough; Double-Blind

1994
Intubation without muscle relaxant: an alternative technique for rapid tracheal intubation.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Alfentanil; Anesthetics, Intravenous; Cough; Double-Blind Method; Elective Surgic

1996
A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Cough; Ele

1999
Antitussive respiratory depressant effects of dextromoramide, fentanyl, morphine, pentazocine, and pethidine during the N2O-O2 anaesthesia in man.
    Annals of clinical research, 1977, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Antitussive Agents; Atropi

1977
Rapid-sequence orotracheal intubation: a comparison of three techniques.
    Anesthesiology, 1990, Volume: 73, Issue:2

    Topics: Abdomen; Adolescent; Adult; Aged; Cough; Electric Stimulation; Humans; Intubation, Intratracheal; Mi

1990

Other Studies

4 other studies available for succinylcholine and Cough

ArticleYear
Experience in the use of laryngeal mask airway in Tikur Anbessa Hospital.
    Ethiopian medical journal, 2002, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Dissociative; An

2002
No support for intravenous lidocaine airway reflex suppression during rapid sequence intubation.
    Annals of emergency medicine, 1995, Volume: 26, Issue:5

    Topics: Asthma; Cough; Drug Therapy, Combination; Humans; Infusions, Intravenous; Intubation, Intratracheal;

1995
Waiting time after non-depolarizing relaxants alter muscle fasciculation response to succinylcholine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:3

    Topics: Adult; Atracurium; Cough; Fasciculation; Female; Humans; Incidence; Intubation, Intratracheal; Male;

1994
[Prevention of succinylcholine-induced muscle cramp with Diazepam].
    Der Anaesthesist, 1966, Volume: 15, Issue:11

    Topics: Adolescent; Adult; Aged; Anesthesia; Cough; Diazepam; Female; Humans; Injections, Intramuscular; Inj

1966