Page last updated: 2024-11-04

succinylcholine and Apnea

succinylcholine has been researched along with Apnea in 381 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Apnea: A transient absence of spontaneous respiration.

Research Excerpts

ExcerptRelevanceReference
" Safe Apnea Time was defined as the time from administration of neuromuscular blocking drugs to oxygen saturation fell to 92%."9.15Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients. ( Huang, S; Li, S; Ma, H; Tang, L; Wang, Z, 2011)
"6 mg/kg would allow a faster recovery of spontaneous ventilation and reduction in the incidence of hemoglobin desaturation during the period of apnea in simulated complete upper airway obstruction situations."9.11Succinylcholine dosage and apnea-induced hemoglobin desaturation in patients. ( Abdullah, K; Alharby, SW; Naguib, M; Riad, W; Samarkandi, AH, 2005)
" Since existing literature recommend a delay of 4 weeks and a subminimal dose of suxamethonium to prevent prolonged apnea, both these points were taken into consideration."8.02Prolonged apnea after ECT in organophosphorus poisoning - the need to redefine norms. ( Dhillon, HS; Sasidharan, S, 2021)
" We present a case of a 35-year-old suicidal man who developed prolonged apnea for almost 4 hours on day 13 of OP poisoning after brief general anesthesia induced by propofol and 1 mg/kg of suxamethonium, during the first session of the third cycle of modified electroconvulsive therapy, despite all due precautions."7.83Prolonged Apnea During Modified Electroconvulsive Therapy in a Patient of Suicidal Attempt by Organophosphorus Poisoning: A Case Report. ( Dhakne, R; Khairkar, P; Kumar, V; Mishra, KK, 2016)
"Butyrylcholinesterase deficiency is characterized by prolonged apnea after the use of muscle relaxants (suxamethonium or mivacurium) in patients who have mutations in the BCHE gene."7.80Characterization of a novel BCHE "silent" allele: point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium. ( Bousquet, A; Ceppa, F; Delacour, H; Lockridge, O; Lushchekina, S; Mabboux, I; Masson, P; Schopfer, LM, 2014)
"Recombinant plant-derived butyrylcholinesterase was capable of counteracting and reversing apnea in two complementary models of lethal succinylcholine toxicity, completely preventing mortality."7.79Reversal of succinylcholine induced apnea with an organophosphate scavenging recombinant butyrylcholinesterase. ( Geyer, BC; Kannan, L; Kilbourne, J; Larrimore, KE; Mor, TS, 2013)
" Apnea for 45 minutes was observed after succinylcholine administration."7.78[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)]. ( Bahar, M; Miller-Roll, T; Negomireanu, S; Pilcha, I; Weksler, N, 2012)
"eleven of 13 patients with a prolonged duration of action of succinylcholine had mutations in BCHE, indicating that this is the possible reason for a prolonged period of apnea."7.77Butyrylcholinesterase gene mutations in patients with prolonged apnea after succinylcholine for electroconvulsive therapy. ( Gätke, MR; Mollerup, HM, 2011)
" Rarely, patients with butyrylcholinesterase deficiency may show marked sensitivity to succinylcholine, manifested clinically by severely prolonged neuromuscular paralysis and apnea."7.77Prolonged neuromuscular paralysis following rapid-sequence intubation with succinylcholine. ( Aiken, DC; Donnell, RW; Kaufman, SE; Magee, C, 2011)
"The best known clinical application of serum BChE assay is to predict abnormally prolonged apnea following the application of the muscle relaxant succinylcholine."7.74Determination of butyrylcholinesterase (BChE) phenotypes to predict the risk of prolonged apnea in persons receiving succinylcholine in the healthy population of western Iran. ( Aminiani, M; Kharazi, H; Kiani, A; Pourmotabbed, T; Rahimi, Z; Tavilani, H; Vaisi-Raygani, A, 2007)
" Thereafter prolonged apnea developed such that the patient had to be admitted to the pediatric intensive care unit."7.72[Emergency from anesthesia in small children. From laryngospasm to prolonged apnea]. ( Gries, A; Motsch, J; Springer, W; Ulmer, HE, 2003)
"Measurement of plasma butyrylcholinesterase (BChE) activity and inhibitor-based phenotyping are standard methods for identifying patients who experience post-succinylcholine (SC) apnea attributable to inherited variants of the BChE enzyme."7.72Butyrylcholinesterase (BCHE) genotyping for post-succinylcholine apnea in an Australian population. ( Burns, JC; Nightingale, BN; Stewart, PM; Sullivan, DR; Yen, T, 2003)
" During the period of apnea and as they were recovering, the volunteers received continuous verbal reassurance by the investigators."7.71Hemoglobin desaturation after succinylcholine-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers. ( Brown, R; Caldwell, JE; Feiner, JR; Heier, T; Lin, J, 2001)
" A 7-h period of apnea and paralysis after administration of succinylcholine was attributed to the decreased rate of succinylcholine metabolism resulting from inhibition of pseudocholinesterase by the insecticide."7.71Prolonged apnea following succinylcholine administration in undiagnosed acute organophosphate poisoning. ( Kocamanoglu, S; Sener, EB; Tur, A; Ustun, E, 2002)
"8) Abnormal variants of serum cholinesterase lead to prolonged apnea."7.67[Phenotype of plasma cholinesterase in prolonged apnea and sensitivity to succinylcholine]. ( Alcalay, A; Burnat, P; Jacquot, C; Zaoui, P, 1987)
"A case of prolonged succinylcholine-induced paralysis in a child with organophosphate insecticide poisoning is presented."7.67Prolonged succinylcholine-induced paralysis in organophosphate insecticide poisoning. ( Curry, SC; Selden, BS, 1987)
"A case of prolonged apnea after administration of succinylcholine in a patient homozygous for the dibucain variant cholinesterase (genotype E1aE1a) has been presented."7.66Prolonged succinylcholine-induced apnea caused by atypical cholinesterase: report of case. ( Aston, R; Mauro, JV; Meyrowitz, MR; Smith, DB, 1980)
"Prolonged apnea (9 hours) after elective orthognathic surgery occurred in a healthy adult female."7.66Prolonged apnea after orthognathic surgery due to atypical cholinesterase. ( Epker, BN; O'Ryan, F, 1981)
" Four of these patients developed prolonged postoperative apnea; the longest period of apnea was 6 hours."7.66Prolonged postoperative apnea complicating gynecologic surgery; atypical cholinesterase and myasthenia gravis. ( Maharry, JM; Sack, RA, 1982)
" Safe Apnea Time was defined as the time from administration of neuromuscular blocking drugs to oxygen saturation fell to 92%."5.15Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients. ( Huang, S; Li, S; Ma, H; Tang, L; Wang, Z, 2011)
"To determine the effects of Magnesium-Sulphate-pretreatment on Suxamethonium-induced complications (serum potassium rise, fasciculations and apnea)."5.12The effects of magnesium sulphate-pretreatment on suxamethonium-induced complications during induction of general endotracheal anaesthesia. ( Danladi, KY; Eyelade, OR; Sotunmbi, PT, 2007)
"(1) To investigate changes in arterial oxygen saturation via pulse oximeter (SpO2) during apnea and after reinstitution of manual ventilation at SpO2 of 95% or 90% following rapid sequence induction of anesthesia in children after 2-minute preoxygenation; (2) to determine whether the setting of a safe threshold of apneic period to an SpO2 of 95% is appropriate in children during anesthetic induction; and (3) to evaluate the influences of age, body weight, and height on the time from the start of apnea to SpO2 of 95%."5.08Study of the safe threshold of apneic period in children during anesthesia induction. ( An, G; Deng, XM; Liao, X; Luo, LK; Tong, SY; Xue, FS, 1996)
", malignant hyperthermia and prolonged apnea after succinylcholine)."5.05Personalized pediatric anesthesia and pain management: problem-based review. ( Hendrickson, M; Horn, N; Packiasabapathy, S; Rangasamy, V; Renschler, J; Sadhasivam, S, 2020)
" Since existing literature recommend a delay of 4 weeks and a subminimal dose of suxamethonium to prevent prolonged apnea, both these points were taken into consideration."4.02Prolonged apnea after ECT in organophosphorus poisoning - the need to redefine norms. ( Dhillon, HS; Sasidharan, S, 2021)
"This is a case of a 32-year-old male-to-female transgender patient with prolonged apnea following ECT treatment for severe, refractory depression."3.85Electroconvulsive Therapy Considerations for Transgendered Patients. ( Adams, DC; Balla, A; Grondin, LS; O'Donnell, SE; Tran, BK; Tsai, MH, 2017)
" We present a case of a 35-year-old suicidal man who developed prolonged apnea for almost 4 hours on day 13 of OP poisoning after brief general anesthesia induced by propofol and 1 mg/kg of suxamethonium, during the first session of the third cycle of modified electroconvulsive therapy, despite all due precautions."3.83Prolonged Apnea During Modified Electroconvulsive Therapy in a Patient of Suicidal Attempt by Organophosphorus Poisoning: A Case Report. ( Dhakne, R; Khairkar, P; Kumar, V; Mishra, KK, 2016)
" BChE deficiency induces a slower hydrolysis of the drug and consequently prolonged neuromuscular block, leading to apnea."3.83[Prolonged neuromuscular block in a patient with butyrylcholinesterase deficiency]. ( Ceppa, F; Courcelle, S; Delacour, H; Hary, B; Mabboux, I, 2016)
"Butyrylcholinesterase deficiency is characterized by prolonged apnea after the use of muscle relaxants (suxamethonium or mivacurium) in patients who have mutations in the BCHE gene."3.80Characterization of a novel BCHE "silent" allele: point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium. ( Bousquet, A; Ceppa, F; Delacour, H; Lockridge, O; Lushchekina, S; Mabboux, I; Masson, P; Schopfer, LM, 2014)
" Apnea for 45 minutes was observed after succinylcholine administration."3.78[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)]. ( Bahar, M; Miller-Roll, T; Negomireanu, S; Pilcha, I; Weksler, N, 2012)
"eleven of 13 patients with a prolonged duration of action of succinylcholine had mutations in BCHE, indicating that this is the possible reason for a prolonged period of apnea."3.77Butyrylcholinesterase gene mutations in patients with prolonged apnea after succinylcholine for electroconvulsive therapy. ( Gätke, MR; Mollerup, HM, 2011)
" Rarely, patients with butyrylcholinesterase deficiency may show marked sensitivity to succinylcholine, manifested clinically by severely prolonged neuromuscular paralysis and apnea."3.77Prolonged neuromuscular paralysis following rapid-sequence intubation with succinylcholine. ( Aiken, DC; Donnell, RW; Kaufman, SE; Magee, C, 2011)
" Homozygotes for the A gene product are at risk for prolonged apnea following exposure to the surgical anesthetics succinylcholine or mivacurium."3.74Molecular basis of succinylcholine sensitivity in a prairie Hutterite kindred and genetic characterization of the region containing the BCHE gene. ( Coghlan, G; Mauthe, J; Triggs-Raine, B; Zelinski, T, 2007)
" Why did the patient have no prolonged apnea and emergence after the previous anesthesia? As the surgical time was exceeded 4 hrs, plasma suxamethonium could fortunately be less than its effective concentration at emergence."3.73[Accidental use of suxamethonium for general anesthesia in a patient with hereditary hypocholinesterasemia that was not recognized preoperatively]. ( Futagami, M; Hashimoto, H; Hirota, K; Ishihara, H; Kitayama, M; Kushikata, T; Sakai, T; Tsutaya, S; Yasujima, M, 2006)
" Thereafter prolonged apnea developed such that the patient had to be admitted to the pediatric intensive care unit."3.72[Emergency from anesthesia in small children. From laryngospasm to prolonged apnea]. ( Gries, A; Motsch, J; Springer, W; Ulmer, HE, 2003)
" On the other hand, the two methods using butyrylthiocholine as substrate and that employing benzoylcholine showed limited clinical utility in discriminating subjects at risk of prolonged apnea (area under the ROC curve < or = 0."3.72Assay using succinyldithiocholine as substrate: the method of choice for the measurement of cholinesterase catalytic activity in serum to diagnose succinyldicholine sensitivity. ( Bonora, R; Ceriotti, F; Franzini, C; Lando, G; Mosca, A; Panteghini, M; Patrosso, MC; Zaninotto, M, 2003)
" Thirteen out of sixteen patients tested after prolonged apnea were positive for the presence of this mutation (50."3.71Rapid identification of atypical variant of plasma butyrylcholinesterase by PCR. ( Benois, A; Burnat, P; Ceppa, F; Fontan, E; Gidenne, S, 2002)
" A 7-h period of apnea and paralysis after administration of succinylcholine was attributed to the decreased rate of succinylcholine metabolism resulting from inhibition of pseudocholinesterase by the insecticide."3.71Prolonged apnea following succinylcholine administration in undiagnosed acute organophosphate poisoning. ( Kocamanoglu, S; Sener, EB; Tur, A; Ustun, E, 2002)
"Succinylcholine and mivacurium are degraded more slowly in patients with a qualitatively or quantitatively reduced plasma cholinesterase and are therefore known for inducing a prolonged postoperative apnea."3.71[Plasma cholinesterase variations as a result of prolonged neuromuscular blockade. Review and problems encountered in two cases of prolonged neuromuscular blockade after muscle relaxation with succinylcholine as compared to mivacurium]. ( Geldner, G; Lang, C; Lukasewitz, P; Wulf, H, 2002)
" Conditions associated with reduced PSC activity lead to sustained action of succinylcholine and result in prolonged apnea."3.70Acquired pseudocholinesterase deficiency after high-dose cyclophosphamide. ( Chan, KW; Chiang, J; Koseoglu, V, 1999)
" Induction doses of ketamine 1 hour after HD exposure resulted in periods of profound apnea, with continued respiratory distress for the next 2 hours."3.70Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard. ( Conley, J; Hamilton, M; Hunter, K; Lundy, P; Sawyer, TW, 2000)
" To the extent allowed by extrapolation from in vitro to in vivo results, this method should increase diagnostic accuracy and may directly predict duration of succinylcholine-induced apnea."3.67A new succinylcholine-based assay of plasma cholinesterase. ( Abernethy, MH; George, PM; Melton, VE, 1984)
"A case of prolonged succinylcholine-induced paralysis in a child with organophosphate insecticide poisoning is presented."3.67Prolonged succinylcholine-induced paralysis in organophosphate insecticide poisoning. ( Curry, SC; Selden, BS, 1987)
"8) Abnormal variants of serum cholinesterase lead to prolonged apnea."3.67[Phenotype of plasma cholinesterase in prolonged apnea and sensitivity to succinylcholine]. ( Alcalay, A; Burnat, P; Jacquot, C; Zaoui, P, 1987)
" Although the method discriminates between cholinesterase activities of drug-sensitive and nonsensitive people as well as an assay involving propionylthiocholine does, it has not revealed cholinesterase abnormalities in patients who experienced prolonged apnea after succinyldicholine, in whom no enzyme defect could be demonstrated by other procedures."3.67Is succinyldicholine the substrate of choice for the measurement of cholinesterase activity? ( Evans, RT; Faye, S, 1986)
"Prolonged apnea (9 hours) after elective orthognathic surgery occurred in a healthy adult female."3.66Prolonged apnea after orthognathic surgery due to atypical cholinesterase. ( Epker, BN; O'Ryan, F, 1981)
"A case of prolonged apnea after administration of succinylcholine in a patient homozygous for the dibucain variant cholinesterase (genotype E1aE1a) has been presented."3.66Prolonged succinylcholine-induced apnea caused by atypical cholinesterase: report of case. ( Aston, R; Mauro, JV; Meyrowitz, MR; Smith, DB, 1980)
" Four of these patients developed prolonged postoperative apnea; the longest period of apnea was 6 hours."3.66Prolonged postoperative apnea complicating gynecologic surgery; atypical cholinesterase and myasthenia gravis. ( Maharry, JM; Sack, RA, 1982)
" Bank blood transfusion prior to or during succinylcholine administration should not significantly alter the duration of action of succinylcholine, and would probably be effective in the management of prolonged apnea resulting from a deficiency of this enzyme."3.66Plasma cholinesterase activity in bank blood. ( Epstein, HM; Jarzemsky, D; Vagher, P; Zuckerman, L, 1980)
"Some patients present prolonged apnea following the administration of succinylcholine because of substantial portion of plasma cholinesterase (the enzyme responsible for the hydrolysis of this muscle relaxant) is present as an atypical variant."3.66[A rare case of silent cholinesterase genetic variant (author's transl)]. ( Andreu, L; Bolinches, R; Bonilla, I; Canós, I; Gil, C; Otte, A, 1980)
"We describe prolonged apnea following electrotherapy in a patient who was also being treated with a topical organophosphate anticholinesterase, ecothiophate iodide (phospholine iodide), for glaucoma."3.66Hazards of succinylcholine administration during electrotherapy. ( Meyer, DA; Packman, PM; Verdun, RM, 1978)
"Prolonged apnea after succinyldicholin is a pharmacogenetic phenomenon."3.65[Succinyldicholin sensitivity resulting from genetically determined serumcholinesterase variants]. ( Benkmann, HG; Goedde, HW; Münsch, H, 1976)
" Because of these reports, 23 patients with prolonged apnea after administration of succinylcholine were studied with Kalow's method for abnormal dibucaine number (DN), which characterizes this condition, and for the history of local anesthetic toxicity."3.65Survey of local anesthetic toxicity in the families of patients with atypical plasma cholinesterase. ( Eilderton, TE; Zsigmond, EK, 1975)
" In spontaneously breathing animals, active hyperventilation (HV) was followed by hyperpnea for up to 30 s and never by apnea."3.65Central neural stimulation of respiration in unanesthetized decerebrate cats. ( Eldridge, FL, 1976)
" Prolonged apnea during anesthesia from administration of succinylcholine caused by homozygosity for this gene, is expected to be extremely rare among populations of Negroes and East Asians."3.64Atypical cholinesterase gene E1a: rarity in Negroes and most Orientals. ( Morrow, A; Motulsky, AG, 1968)
"Morbid obesity is associated with a reduction in time to desaturate during apnoea following standard pre-oxygenation and induction of anaesthesia."2.70Effectiveness of continuous positive airway pressure to enhance pre-oxygenation in morbidly obese women. ( Berthoud, MC; Cressey, DM; Reilly, CS, 2001)
"A patient, with a history of cretinism, who developed suxamethonium apnoea as a consequence of a reduction in plasma cholinesterase activity secondary to the concurrence of pregnancy and liver dysfunction associated with pre-eclampsia is reported."1.27Suxamethonium apnoea associated with pregnancy and liver dysfunction in a treated cretin. ( Britten, JJ; Ferguson, A; Perriss, BW; Whittaker, M, 1983)

Research

Studies (381)

TimeframeStudies, this research(%)All Research%
pre-1990291 (76.38)18.7374
1990's31 (8.14)18.2507
2000's28 (7.35)29.6817
2010's24 (6.30)24.3611
2020's7 (1.84)2.80

Authors

AuthorsStudies
Acharya, S1
Bhattarai, S1
Shrimanker, I1
Gupta, SS1
Wang, J1
Han, X1
Cang, J1
Miao, C1
Liang, C1
Packiasabapathy, S1
Rangasamy, V1
Horn, N1
Hendrickson, M1
Renschler, J1
Sadhasivam, S1
Cornelius, BW1
Jacobs, TM1
Mintjens, N1
Brummans, R1
Soetens, F1
Claes, KBM1
Vanlinthout, LE1
Sasidharan, S1
Dhillon, HS1
Millet, C1
Plaud, B1
Delacour, H3
Balme, K1
McCulloch, M1
Stephen, C1
Robles, A1
Michael, M1
McCallum, R1
Andersson, ML1
Møller, AM1
Wildgaard, K1
Geyer, BC1
Larrimore, KE1
Kilbourne, J1
Kannan, L1
Mor, TS1
Dillon, D1
Lee, P1
Yuksel, E1
Sergin, D1
Tanatti, B1
Alper, I1
Zoller, M1
Walther, S1
Cassel, J1
Staehr-Rye, AK1
Nielsen, CV2
Gätke, MR3
Brozović, G1
Mazul Sunko, B1
Hafner, T1
Bekavac, I1
Lushchekina, S1
Mabboux, I2
Bousquet, A1
Ceppa, F4
Schopfer, LM1
Lockridge, O3
Masson, P1
Thomsen, JL1
Palmqvist, DF1
Alvarellos, ML1
McDonagh, EM1
Patel, S1
McLeod, HL1
Altman, RB1
Klein, TE1
Dhakne, R1
Mishra, KK1
Kumar, V1
Khairkar, P1
Hary, B1
Courcelle, S1
Sellers, WF1
Binkley, C1
Tran, BK1
O'Donnell, SE1
Balla, A1
Adams, DC1
Grondin, LS1
Tsai, MH1
Kalow, W4
Taha, SK1
El-Khatib, MF1
Baraka, AS1
Haidar, YA1
Abdallah, FW1
Zbeidy, RA1
Siddik-Sayyid, SM1
Greenwood, M1
Meechan, JG1
Mollerup, HM1
Dawson, JS1
Tang, L1
Li, S1
Huang, S1
Ma, H1
Wang, Z1
Kaufman, SE1
Donnell, RW1
Aiken, DC1
Magee, C1
Miller-Roll, T1
Pilcha, I1
Weksler, N1
Negomireanu, S1
Bahar, M1
Sener, EB1
Ustun, E1
Kocamanoglu, S1
Tur, A1
Gidenne, S1
Benois, A1
Fontan, E1
Burnat, P3
Gries, A1
Motsch, J1
Ulmer, HE1
Springer, W1
Mosca, A1
Bonora, R2
Ceriotti, F1
Franzini, C1
Lando, G1
Patrosso, MC1
Zaninotto, M1
Panteghini, M2
Dabas, R1
Vohra, SB1
Yen, T1
Nightingale, BN1
Burns, JC1
Sullivan, DR1
Stewart, PM1
FORBAT, A1
LEHMANN, H5
SILK, E4
ANDERSON, HJ1
CHURCHILL-DAVIDSON, HC1
RICHARDSON, AT1
NILSSON, E1
HARRISON, BL1
SEWARD, EH1
SKINNER, LC1
COWAN, KA1
HODGES, RJ1
HARKNESS, J1
CALVERT, J1
SLACK, WK1
WIDMARK, H1
STOVNER, J2
LIND, B1
JOHNSON, PD1
ARGENT, DE1
DINNICK, OP1
HOBBIGER, F1
BRENNAN, HJ1
PALETZ, SG1
BETTSCHART, A2
BOVET, D2
SCOGNAMIGLIO, W2
GUNN, DR1
SAMSON, HH1
FRASCARIA, F2
SIMMONS, PH1
HAMELBERG, W1
BARKER, JC1
MAY, A1
FILIS, CP1
JORGENSEN, S1
PETERSEN, H1
LAFLEUR, F1
VEGETO, A1
ROSSI, E1
ABRAMS, MW1
GINSBERG, H1
INCZE, F1
CSERNOHORSZKY, V1
AVAKIAN, AV1
GULANIAN, KA1
BUSH, GH2
DOENICKE, A4
HOLLE, F1
FREY, HH1
LEROY, JG1
COLLE, JI1
FOLDES, FF2
LUNN, JN1
BENZ, HG1
GIANI, E1
NASTRI, D1
D'AURIA, C1
HEIFETZ, M1
BIRKHAN, HJ1
SANDERSON, RE2
CAMPBELL, D2
LAVERTY, SG2
KLEINE, U1
KRAUSE, E1
KATSURASHIMA, T1
VICKERS, MD4
TELFER, AB1
MACDONALD, DJ1
DINWOODIE, AJ1
KELLY, M1
LIDDELL, J2
GOEDDE, HW12
ALTLAND, K6
BROSS, K1
CROPPER, CF1
HUGHES, M1
BRUMLIK, J1
MIER, M1
PETROVICK, M1
JENSEN, HP1
NIXON, JC1
THIEL, CJ1
SFORZA, I1
CLARKE, RS1
DUNDEE, JW1
DAW, RH1
OZORIO, HP1
HARRIS, H1
DEBLASI, S1
JACKSON, BG1
GEE, EC1
LAWS, AK1
MCCANN, B1
BOURKE, JR1
MATTHEW, JR1
CONSTAN, E1
WHITTAKER, M11
BAITSCH, H1
PAVONE, G1
ZEITLIN, GL1
SHORT, DH1
FIELDING, ME1
MCCOMB, RB1
LAMOTTA, RV1
WETSTONE, HJ1
BRODY, IA1
RESNICK, JS1
ENGEL, WK1
DAVIDOV, S1
KAUFMAN, L1
KOERNER, M1
LOTSHAW, RL1
RUBINSTEIN, HM4
ROSENBERG, MK1
BOLGLA, JH1
COHEN, BM1
PRAKHOV, NV1
RUDDELL, JS1
Norris, JC1
Barker, I1
Harle, CC1
McKendrick, R1
Goodall, R1
Strock, D1
Kuczkowski, KM1
Greenberg, M1
Naguib, M1
Samarkandi, AH1
Abdullah, K1
Riad, W1
Alharby, SW1
Kenane, N1
Chellak, S1
Bigaillon, C1
El-Orbany, MI1
Joseph, NJ2
Salem, MR2
Alexander, R1
Fardell, S1
Hashimoto, H1
Kushikata, T1
Kitayama, M1
Ishihara, H1
Hirota, K1
Sakai, T1
Futagami, M1
Yasujima, M1
Tsutaya, S1
Zelinski, T1
Coghlan, G1
Mauthe, J1
Triggs-Raine, B1
Vaisi-Raygani, A2
Rahimi, Z1
Kharazi, H1
Tavilani, H1
Aminiani, M1
Kiani, A1
Pourmotabbed, T1
Karmarkar, A1
DeMello, W1
Danladi, KY1
Sotunmbi, PT1
Eyelade, OR1
De Jong, RH1
Wagman, IH1
Prince, DA1
Theodore, J1
Millen, JE1
Murdaugh, HV1
Robin, ED1
Clancy, J1
Vanderhoof, E1
Campbell, P1
Himes, JA1
Edds, GT1
Kirkham, WW1
Neal, FC1
Nolan, RT1
Anderson, KS1
Kendall, JD1
Abernethy, MH1
George, PM1
Melton, VE1
Chautard-Freire-Maia, EA1
Carvalho, RD1
da Silva, MC1
Souza, MG1
Azevedo, ES1
Deam, D1
Emmanuel, ER1
Bevan, DR1
Donati, F1
Galley, RL1
O'Ryan, F1
Epker, BN1
Owen, H1
Hunter, AR4
Oshita, S1
Sari, A1
Fujii, S1
Yonei, A1
Ferguson, A1
Britten, JJ1
Perriss, BW1
Meyrowitz, MR1
Mauro, JV1
Aston, R1
Smith, DB1
Datta, S1
Alper, MH1
Brown, SS3
Pilz, W3
Woronick, CL1
Moore, DC1
Morgan, AA2
Gabrielsen, J1
Valentin, N1
Valle Sánchiz, J1
Herraiz Domínguez, V1
Gracia Vidal, C1
Botello Aguado, C1
Ascorve Domínquez, A1
Maharry, JM1
Sack, RA1
Jackson, SH1
Bailey, GW1
Stevens, G1
Chung, SJ1
Andrews, D1
Mohandas, K1
Sivaneswaran, N2
Inbasegaran, K1
Epstein, HM1
Jarzemsky, D1
Zuckerman, L1
Vagher, P1
Evans, RT6
Iqbal, J1
Dietz, AA4
Lubrano, T3
Alvarez Gómez, JA2
Alvarez Ossorio, R2
Aguilar Alenda, R1
Lozano Tonkin, E1
López López, H1
Rosa Riquelme, M1
Bernal García, G1
Díaz Cayuela, A1
Pérez Guillermo, F2
Button, C1
Bertschinger, HJ1
Mülders, MS1
Jayasuriya, JP1
Lanks, KW1
Sklar, GS1
MacDonald, R1
Robinson, A1
El-Hawary, KA1
El-Kateb, HM1
Hussein, SM1
Atallah, MD1
Otte, A2
Bonilla, I1
Gil, C2
Bolinches, R2
Andreu, L2
Canós, I1
Wroe, JM1
Viby-Mogensen, J5
Pasquariello, CA2
Schwartz, RE2
Jensen, FS1
Vassallo, SA1
Goudsouzian, NG1
Mitchell, JB1
Harrop-Griffiths, W1
Roux, A1
Ansermino, JM1
Taylor, A1
McCarroll, M1
Frawley, GP1
Carden, JR1
Stone, RJ1
Smith, DC2
Ridley, SA1
Donaldson, KF1
Davidson, A1
Brown, TC1
Blanloeil, Y1
Delaroche, O1
Tequi, B1
Gunst, JP1
Dixneuf, B1
Xue, FS1
Luo, LK1
Tong, SY1
Liao, X1
Deng, XM1
An, G1
Aguilar-Aguilar, G1
Aguilar-Olmos, JM1
Gil-Minguillón, C1
Gómez-Casals, V1
Rodríguez-Camps, S1
Michel, D1
Simon, L1
Garbay, MM1
Sacquin, P1
Hamza, J1
Saint-Maurice, C1
Baraka, A2
Davies, P1
Landy, M1
Simeon-Rudolf, V1
Kovarik, Z1
Skrinjarić-Spoljar, M1
Carrión Pareja, JC1
Candel Calderón, M1
Orcastegui, JL1
Ho, VW1
Osiovich, H1
Koseoglu, V1
Chiang, J1
Chan, KW1
McLoughlin, L1
Conley, J1
Hunter, K1
Lundy, P1
Hamilton, M1
Sawyer, TW1
Heier, T1
Feiner, JR1
Lin, J1
Brown, R1
Caldwell, JE1
Cressey, DM1
Berthoud, MC1
Reilly, CS1
Kopman, AF1
Adnet, F1
Borron, SW1
Lapostolle, F1
Boeck, AT1
Fry, DL1
Sastre, A1
Lang, C1
Lukasewitz, P1
Wulf, H1
Geldner, G1
Bach, PH1
Wingfield, ES1
Leary, WP1
Bach, F1
Turner, H1
King, J3
Canos, J1
Rogla, F1
Agarwal, DP3
Schwenkenbecher, S1
Srivastava, LM2
Poulton, TJ1
James, FM1
Hanel, HK5
Hansen, E1
Graae, J1
Gerosky, T1
O'Leary, J1
Hunt, R1
Hutchinson, MA1
Keller, H1
Müller, R1
Hutter, CD1
McQueen, MJ2
Lepinskie, F1
Strickland, RD1
Trimble, A1
Candy, JJ1
Packman, PM1
Meyer, DA1
Verdun, RM1
Roglá Benedito, F1
Corcuera Linares, F1
Andreu Miquel, L1
Canos Llacer, I1
Bolinches Bolinches, R1
Avery, D1
Finn, R1
Scholler, KL4
Benkmann, HG2
Chan, CS1
Robinson, JD1
Lam, KT1
Stadskleiv, K1
Mogensen, JV2
Münsch, H2
Dewar, FM1
Wakefield, G1
Zsigmond, EK3
Eilderton, TE2
Precious, DS1
Kuriyama, K1
Price, EM1
Guarneri, G1
Caporali, C1
Savoldi, R1
Haroun, S1
Bassili, M1
Abu-Haider, G1
Pronk, IR1
van der Wal, SJ1
Thé, TH1
Berry, M1
Das, PK1
Eldridge, FL1
Pannall, PR1
Potgieter, GM1
Raubenheimer, MM1
Benzer, A1
Luz, G1
Oswald, E1
Schmoigl, C1
Menardi, G1
Huang, JS1
Talbot, AR1
Chen, CL1
Gill, RS1
O'Connell, N1
Scott, RP1
Walker, L1
Griffiths, D1
Earl, P1
Fridliand, MI1
Zinevich, VP1
Clarke, C1
Lindsay, RG1
Mets, B1
Woolf, BH1
Selden, BS1
Curry, SC1
Velin, P1
Dupont, D1
Lainé-Cessac, P1
Turcant, A1
Allain, P1
Weeks, DB1
Ford, D1
Ritter, DM1
Rettke, SR1
Ilstrup, DM1
Burritt, MF2
Pagani, F1
Martinez Pretel, CM1
Tarín Royo, F1
Peña Macias, MJ1
Vidal, CJ1
Jacquot, C1
Alcalay, A1
Zaoui, P1
Mehta, Y1
Hole, P1
Faye, S1
Nelson, TC1
Sapsford, DJ1
Barkai, AI1
Barrie, H1
Miller, G1
Gualandi, W2
Bonfanti, G1
Magbagbeola, JA1
Lemaire, WJ1
Nagel, EL1
Smith, JC2
Gibb, DB1
Katz, RL1
Gissen, AJ1
Benatar, SR1
Figueroa, M1
Weis, KH1
Bauld, HW1
Gibson, PF2
Jebson, PJ1
Markoff, N1
Ernst, FW1
Poweleit, AC1
Walker, IR1
Zapf, PW1
Mackay, IR1
Kimbrough, RD2
Suggs, JE2
Cohen, SN1
Weber, WW1
Foley, EI1
Walton, B1
Savege, TM1
Strunin, L1
Simpson, BR1
Whitford, JH1
Cory, CE1
Beddard, JB1
Rosalki, SB1
Davidson, WS1
Pembrey, ME1
Griffin, D1
Subrahmanyam, HS1
Micheli, A1
Rink, RA1
Husain, M1
Purry, NA1
Jardine, WI1
Ferguson, AS1
Sinton, RI1
Happle, R1
Lubin, AH1
Garry, PJ2
Owen, GM1
Horne, J1
Watson, TD1
Giesecke, AH1
Raj, PR1
Ahlgren, EW1
Nelson, RA1
Miller, T1
Miguel Martínez, J1
Miguel Magro, E1
McStravog, LJ1
Richardson, RB1
Derrick, WS1
Prince, LC1
Notari, RE1
Jenkins, AV1
Sammons, HG1
Goedee, HW1
Mone, JG1
Mathie, WE1
Simpson, NE1
Schloot, W1
Peck, AW1
Wildsmith, JA1
Garner, M1
Rubinstein, H1
Varma, YS1
Sharma, PL1
Singh, HW1
Wulfsohn, NL1
Fishtal, A1
Chapman, CN1
Baer, G1
Avery, WG1
Sackner, MA1
Bourne, JG1
Dal Prato, G1
Magni, E1
Pascale, M1
Pasini, G1
Short, CE1
Cuneio, J1
Cupp, D1
Bellucci, G1
La Cour, D1
Juul-Jensen, P1
Reske-Nielsen, E1
McLellan, GH1
Billings, JD1
Chasapakis, G2
Dimas, C1
Augustaki, O1
Kekis, N1
Philippou, P1
Moraitis, H1
Floras, A1
Makkous, A1
Seybold, R2
Bräutigam, KH2
Gesing, H1
Krumey, I2
Schmidinger, S2
Carson, SA1
Chorley, GE1
Hamilton, FN1
Lee, DC1
Morris, LE1
Martínez Hernández, A1
Jacobson, A1
Hankla, I1
Soshnikov, EI1
Durinian, RA1
Safonov, VA1
Cohen, PJ1
Reynolds, RC1
Naidl, J1
Hazel, B1
Monier, D1
Trempe, L1
Beauchemin, M1
Rondeau, Y1
Castles, TR1
Loth, E1
Crawford, CR1
Lee, CC1
Don, HF1
Wahba, M1
Cuadrado, L1
Kelkar, K1
Litwiller, RW1
Ross, DM1
Morgan, HG1
Morillo Conejo, A1
Gasco García, MC1
Cirac Andreu, L1
Vetten, KB1
Rex, MA1
Downs, JR1
Hörlein, H2
Bimonte, D1
Merola, L1
Serra, E1
Susini, F1
Oda, M1
Patané, S1
Bellelli, M1
Russo, S1
Arcerito, S1
Motulsky, AG1
Morrow, A1
Farrar, CH1
Powell, BJ1
Martin, LK1
Cherniack, NS1
Longobardo, GS1
Palermo, FP1
Heymann, M1
Zoerb, DL1
Robertson, GS1
Hains, J1
Brodeur, J1
Martin, P1
Authier, L1
Lebel, E1
Pitts, FN1
Woodruff, RA1
Craig, AG1
Rich, CL1
Sonnino, S1
Funke, LA1
La Marra, C1
Marrollo, E1
Fantera, A1
Simon, NM1
Del Greco, F1
Bodley, PO1
Halwax, K1
Potts, L1
Walker, JA1
Artz, CP1
Guillet, GG1
Craig, HV1
Demeester, P1
Bettex, M2
Schärli, A2
Pallini, C1
Saba, GM1
Sandoli, A1
Tigano, U1
Grohmann, W1
Sato, M1
Köhler, H1
Szeinberg, A1
Pipano, S1
Ostfeld, E1
Impastato, DJ1
Gesztes, T1
Thompson, JC1
Leacock, AM1
Campbell, DJ1
McIntyre, JW1
Madill, MF1
Vandewater, SL1
Lavoie, G1
List, WF1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"A Less-rapid Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the Duration of Apnea Without Desaturation in Paralyzed Non-obese and Morbidly Obese Patients?"[NCT02943629]0 participants (Actual)Interventional2016-11-30Withdrawn (stopped due to Lack of feasibility)
Preoxygenation With Optiflow™, a High Flow Nasal Cannula (HFNC), is Superior to Preoxygenation With Facemask in Morbidly Obese Patients Undergoing General Anesthesia[NCT03009877]0 participants (Actual)Interventional2018-07-31Withdrawn (stopped due to withdrawn prior to IRB approval)
Apneic Oxygenation With a Nasal Cannula in the Obese and Morbidly Obese Surgical Patient: A Randomized, Double-Blinded, Placebo-Controlled Trial[NCT03671837]135 participants (Actual)Interventional2017-07-12Completed
EPO2-A: Evaluation of Different Pre-Oxygenation Condition in Morbid Obesity: Effect of Position and Positive Pressure Ventilation During General Anesthesia Induction[NCT02590406]50 participants (Actual)Interventional2015-09-30Completed
Effect of Intravenous Infusion of Magnesium Sulfate Associated or Not to Lidocaine On the Neuromuscular Blockade Induced by Muscle Relaxant Cistracurium[NCT02483611]Phase 448 participants (Actual)Interventional2015-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Maximum Expired Fraction of Oxygen Obtained

Evaluation of the maximum expired oxygen fraction obtained in the two groups (NCT02590406)
Timeframe: After 3 minutes of pre-oxygenation

InterventionMaximum expired fraction of oxygen obtai (Mean)
Beach Chair (BC) and ZEEP0.89
Reverse Trendelenburg and NIPPV0.91

Minimum Arterial Saturation of Oxygen Obtained

Evaluation of the minimal saturation obtained after the resumption of the ventilation (NCT02590406)
Timeframe: After the end of the Non-hypoxic apnea time

Interventionpercent (Mean)
Beach Chair (BC) and ZEEP83.6
Reverse Trendelenburg and NIPPV85.3

Non Hypoxic Apnea Time

Change of Non-hypoxic apnea time in obese patient during a General Anesthesia induction, as a result of different pre-oxygenation position and ventilation mode; 1-Beach Chair and No positive pressure ventilation, 2-Reverse Trendelenburg and positive pressure ventilation and PEEP. End of measure time frame is 5 minutes after intubation (NCT02590406)
Timeframe: After a 3 minutes pre-oxygenation period

Interventionseconds (Mean)
Beach Chair (BC) and ZEEP216.7
Reverse Trendelenburg and NIPPV258.2

Time to 97% Saturation

(NCT02590406)
Timeframe: Evaluation of the time needed to the beginning of the ventilation to the moment where the saturation is 97%

Interventionseconds (Mean)
Beach Chair (BC) and ZEEP88.4
Reverse Trendelenburg and NIPPV68

Time to Expired Oxygen Fraction > 0,9

Evaluation of time needed to obtain an expired fraction of oxygen of > 0,9 in the two groups during the pre-oxygenation (NCT02590406)
Timeframe: During the pre-oxygenation period

Interventionseconds (Mean)
Beach Chair (BC) and ZEEP145.3
Reverse Trendelenburg and NIPPV85.1

Clinical Duration

"The clinical duration is the elapsed time for T1 recovery = 25% (Dur25%) of the original value of T1 after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Interventionminutes (Median)
Group M82.68
Group ML86.33
Group C64.8

Final Recovery Index

"The final recovery index is the elapsed time between the T1 recovery = 25% (Dur25%) and T4 / T1 = 80% (TOF = 80%) after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Interventionminutes (Mean)
Group M27.97
Group ML33.81
Group C21.51

HR - M1 (Heart Rate in the Moment 1)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The measure of heart rate was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of heart rate was performed when the patient arrived in the operating room

Interventionbeats/min (Mean)
Group M79.94
Group ML77.25
Group C73.66

HR - M2 (Heart Rate in the Moment 2)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before induction of anesthesia

Interventionbeats/min (Mean)
Group M74.69
Group ML73.69
Group C75.40

HR - M3 (Heart Rate in the Moment 3)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)

Interventionbeats/min (Mean)
Group M72.94
Group ML74.19
Group C75.40

HR - M4 (Heart Rate in the Moment 4)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as in the end of the study solutions infusion. This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of heart rate was performed five minutes after M3 (in the end of the X and Y solutions infusion)

Interventionbeats/min (Mean)
Group M71.94
Group ML72.25
Group C65.07

HR - M5 (Heart Rate in the Moment 5)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of heart rate was performed immediately before the tracheal intubation

Interventionbeats/min (Mean)
Group M67.56
Group ML69.31
Group C64.27

HR - M6 (Heart Rate in the Moment 6)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of heart rate was performed one minute after the tracheal intubation

Interventionbeats/min (Mean)
Group M66.50
Group ML68.19
Group C65.13

HR - M7a (Heart Rate in the Moment 7a)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 15 minutes after the traqueal intubation.This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of heart rate was performed 15 minutes after the traqueal intubation

Interventionbeats/min (Mean)
Group M68.94
Group ML68.19
Group C67.13

HR - M7b (Heart Rate in the Moment 7b)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of heart rate was performed 30 minutes after the traqueal intubation

Interventionbeats/min (Mean)
Group M67.44
Group ML68.38
Group C64.00

HR - M7c (Heart Rate in the Moment 7c)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of heart rate was performed 45 minutes after the traqueal intubation

Interventionbeats/min (Mean)
Group M65.75
Group ML65.75
Group C62.33

HR - M7d (Heart Rate in the Moment 7d)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of heart rate was performed 60 minutes after the traqueal intubation

Interventionbeats/min (Mean)
Group M66.19
Group ML65.31
Group C61.93

HR - M7e (Heart Rate in the Moment 7e)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of heart rate was performed 75 minutes after the traqueal intubation

Interventionbeats/min (Median)
Group M66.50
Group ML63.00
Group C58.00

HR - M7f (Heart Rate in the Moment 7f)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The heart rate was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of heart rate was performed 90 minutes after the traqueal intubation

Interventionbeats/min (Median)
Group M66.00
Group ML61.00
Group C61.00

Latency

"The latency is computed as the elapsed time to reduce the response of T1 to 5% of the initial contraction force after the infusion of cisatracurium.~This outcome meansure was presented in seconds." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Interventionseconds (Mean)
Group M139.70
Group ML151.30
Group C147.80

MAP - M1 (Mean Arterial Pressure in the Moment 1)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the arrival of the patient in the operating room. This time point was named as moment '1'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed when the patient arrived in the operating room

InterventionmmHg (Mean)
Group M94.63
Group ML88.75
Group C100.10

MAP - M2 (Mean Arterial Pressure in the Moment 2)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the moment immediately before the anesthesia induction. This time point was named as moment '2'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before induction of anesthesia

InterventionmmHg (Mean)
Group M87.63
Group ML84.69
Group C92.47

MAP - M3 (Mean Arterial Pressure in the Moment 3)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution). This time point was named as moment '3'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the start of the infusion of the solution X (magnesium sulfate or isotonic solution) and Y solution (lidocaine or isotonic solution)

InterventionmmHg (Mean)
Group M75.88
Group ML73.88
Group C76.73

MAP - M4 (Mean Arterial Pressure in the Moment 4)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as in the end of the study solutions infusion.This time point was named as moment '4'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed five minutes after M3 (in the end of the X and Y solutions infusion)

InterventionmmHg (Median)
Group M69.00
Group ML63.00
Group C74.00

MAP - M5 (Mean Arterial Pressure in the Moment 5)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as immediately before the tracheal intubation. This time point was named as moment '5'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed immediately before the tracheal intubation

InterventionmmHg (Median)
Group M62.50
Group ML61.50
Group C67.00

MAP - M6 (Mean Arterial Pressure in the Moment 6)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as one minute after the tracheal intubation. This time point was named as moment '6'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed one minute after the tracheal intubation

InterventionmmHg (Median)
Group M64.50
Group ML64.00
Group C69.00

MAP - M7a (Mean Arterial Pressure in the Moment 7a)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 15 minutes after the traqueal intubation. This time point was named as moment '7a'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 15 minutes after the traqueal intubation

InterventionmmHg (Median)
Group M66.00
Group ML61.50
Group C69.00

MAP - M7b (Mean Arterial Pressure in the Moment 7b)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 30 minutes after the traqueal intubation. This time point was named as moment '7b'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 30 minutes after the traqueal intubation

InterventionmmHg (Median)
Group M66.50
Group ML63.50
Group C68.00

MAP - M7c (Mean Arterial Pressure in the Moment 7c)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 45 minutes after the traqueal intubation. This time point was named as moment '7c'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 45 minutes after the traqueal intubation

InterventionmmHg (Mean)
Group M69.25
Group ML63.00
Group C69.00

MAP - M7d (Mean Arterial Pressure in the Moment 7d)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 60 minutes after the traqueal intubation. This time point was named as moment '7d'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 60 minutes after the traqueal intubation

InterventionmmHg (Median)
Group M68.00
Group ML62.00
Group C66.00

MAP - M7e (Mean Arterial Pressure in the Moment 7e)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 75 minutes after the traqueal intubation. This time point was named as moment '7e'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 75 minutes after the traqueal intubation

InterventionmmHg (Median)
Group M68.00
Group ML66.00
Group C69.00

MAP - M7f (Mean Arterial Pressure in the Moment 7f)

In the operating room, patients were cardiovascular, respiratory and body temperature monitored through the Dixtal 2020. The mean blood pressure was recorded and annotated at various times such as 90 minutes after the traqueal intubation. This time point was named as moment '7f'. (NCT02483611)
Timeframe: This measure of average blood pressure was performed 90 minutes after the traqueal intubation

InterventionmmHg (Median)
Group M64.00
Group ML64.50
Group C72.00

Recovery Index

"The recovery index is the elapsed time between the T1 recovery =25% (Dur25%) and T1 =75% (Dur75%) after the infusion of cisatracurium.~This outcome meansure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Interventionminutes (Mean)
Group M20.08
Group ML20.26
Group C14.53

Spontaneous Recovery (T4/T1=90%)

"Spontaneous recovery is the elapsed time for the recovery of the TOF (T4 / T1) response to 90% of the original after infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: The participants were followed during the anesthetic - surgical procedure

Interventionminutes (Mean)
Group M120.20
Group ML126.70
Group C90.03

Total Duration (Dur95%)

"The total duration is the elapsed time for T1 recovery of the response to reach 95% of the initial after the infusion of cisatracurium.~This outcome measure was presented in minutes." (NCT02483611)
Timeframe: Participants were followed during the anesthetic - surgical procedure, an average of 90 minutes

Interventionminutes (Mean)
Group M113.20
Group ML120.10
Group C88.19

Reviews

18 reviews available for succinylcholine and Apnea

ArticleYear
Personalized pediatric anesthesia and pain management: problem-based review.
    Pharmacogenomics, 2020, Volume: 21, Issue:1

    Topics: Anesthesia; Anesthesiology; Apnea; Child; Child, Preschool; Humans; Malignant Hyperthermia; Pain; Pa

2020
Pseudocholinesterase Deficiency: What the Proceduralist Needs to Know.
    The American journal of the medical sciences, 2019, Volume: 357, Issue:3

    Topics: Anesthesia, General; Apnea; Butyrylcholinesterase; Dilatation; Endoscopy; Esophageal Achalasia; Huma

2019
Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review.
    Anaesthesia, 2019, Volume: 74, Issue:4

    Topics: Anesthesia; Apnea; Butyrylcholinesterase; Humans; Metabolism, Inborn Errors; Mivacurium; Neuromuscul

2019
PharmGKB summary: succinylcholine pathway, pharmacokinetics/pharmacodynamics.
    Pharmacogenetics and genomics, 2015, Volume: 25, Issue:12

    Topics: Apnea; Butyrylcholinesterase; Calcium Channels; Calcium Channels, L-Type; Humans; Hyperkalemia; Mali

2015
Cholinesterase: phenotyping and genotyping.
    Annals of clinical biochemistry, 2004, Volume: 41, Issue:Pt 2

    Topics: Acetylcholinesterase; Amino Acid Substitution; Apnea; Butyrylcholinesterase; Cholinesterase Inhibito

2004
Plasma cholinesterase variants and the anaesthetist.
    Anaesthesia, 1980, Volume: 35, Issue:2

    Topics: Adult; Anesthesia; Apnea; Cholinesterases; Female; Gene Frequency; Genes; Genetic Variation; Genotyp

1980
Anesthesia for cesarean section.
    Anesthesiology, 1980, Volume: 53, Issue:2

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Intravenous; Anesthesia, Spinal; Anesthetics;

1980
The plasma cholinesteerases: a new perspective.
    Advances in clinical chemistry, 1981, Volume: 22

    Topics: Acetylcholinesterase; Anesthesia, General; Apnea; Cholinesterases; Dibucaine; Fluorides; Genes; Gene

1981
Local anesthetic drugs: tissue and systemic toxicity.
    Acta anaesthesiologica Belgica, 1981, Volume: 32, Issue:4

    Topics: Anesthesia, Conduction; Anesthetics, Local; Animals; Apnea; Arrhythmias, Cardiac; Barbiturates; Cent

1981
[Genetically determined variations in drug response (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1975, Apr-01, Volume: 20, Issue:5

    Topics: Acetyltransferases; Animals; Apnea; Butyrylcholinesterase; Cholinesterases; Genetic Variation; Gluco

1975
Pharmacogenetics.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:1

    Topics: Analgesics; Anemia, Hemolytic; Anesthetics; Apnea; Bone Marrow Diseases; Child; Child, Preschool; Ch

1972
Uses and limitations of enzyme tests.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:7

    Topics: Alcoholism; Apnea; Child; Clinical Enzyme Tests; Diagnosis, Differential; Female; Hepatitis A; Heter

1974
Studies of aversive conditioning for alcoholics: a critical review of theory and research methodology.
    Psychological bulletin, 1974, Volume: 81, Issue:9

    Topics: Acoustic Stimulation; Alcohol Drinking; Alcoholism; Apnea; Aversive Therapy; Conditioning, Classical

1974
Pharmacogenetics.
    The Practitioner, 1974, Volume: 213, Issue:1277

    Topics: Acetyltransferases; Administration, Topical; Alleles; Analgesics; Anemia, Hemolytic; Anti-Inflammato

1974
[Pharmacogenetic problems in anesthesia].
    Der Anaesthesist, 1966, Volume: 15, Issue:1

    Topics: Anesthesia; Apnea; Cholinesterases; Female; Genetics, Medical; Humans; Hypothermia, Induced; Male; P

1966
Pharmacogenetics. Cholinesterase variants and suxamethonium apnoea.
    Proceedings of the Royal Society of Medicine, 1968, Volume: 61, Issue:2

    Topics: Alleles; Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Drug Hypersensitivity; Electr

1968
[Cholinesterase. A survey with particular reference to inherited increase in sensitivity to suxamethonium].
    Nordisk medicin, 1970, Nov-05, Volume: 84, Issue:45

    Topics: Apnea; Blood Transfusion; Cholinesterases; Drug Hypersensitivity; Genes, Recessive; Humans; Metaboli

1970
[Genetically dependent variability of drug effects].
    Medizinische Klinik, 1970, Aug-28, Volume: 65, Issue:35

    Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temp

1970

Trials

13 trials available for succinylcholine and Apnea

ArticleYear
Rapid sequence induction with a "modified timing principle" of rocuronium provides excellent intubating conditions: A randomised trial.
    Anaesthesia, critical care & pain medicine, 2022, Volume: 41, Issue:4

    Topics: Androstanols; Apnea; Humans; Intubation, Intratracheal; Neuromuscular Nondepolarizing Agents; Propof

2022
Effect of suxamethonium vs rocuronium on onset of oxygen desaturation during apnoea following rapid sequence induction.
    Anaesthesia, 2010, Volume: 65, Issue:4

    Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Fasci

2010
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:2

    Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter

2011
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:2

    Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter

2011
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:2

    Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter

2011
Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:2

    Topics: Adult; Androstanols; Anesthesia, General; Apnea; Blood Gas Analysis; Body Mass Index; Endpoint Deter

2011
Succinylcholine dosage and apnea-induced hemoglobin desaturation in patients.
    Anesthesiology, 2005, Volume: 102, Issue:1

    Topics: Adult; Anesthesia Recovery Period; Apnea; Body Mass Index; Diaphragm; Dose-Response Relationship, Dr

2005
Tracheal intubating conditions and apnoea time after small-dose succinylcholine are not modified by the choice of induction agent.
    British journal of anaesthesia, 2005, Volume: 95, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Apnea; Dose-Response Relationship,

2005
The effects of magnesium sulphate-pretreatment on suxamethonium-induced complications during induction of general endotracheal anaesthesia.
    African journal of medicine and medical sciences, 2007, Volume: 36, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics; Apnea; Fasciculation; Female; Humans; Hyperkalemia; Intubat

2007
Plasma cholinesterase and abnormal reaction to succinylcholine: twenty years' experience with the Danish Cholinesterase Research Unit.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:2

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Denmark; Electric Stimulation; Female; Genes; Genetic

1995
Study of the safe threshold of apneic period in children during anesthesia induction.
    Journal of clinical anesthesia, 1996, Volume: 8, Issue:7

    Topics: Age Factors; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Body Height; Body Weight; Bra

1996
Effectiveness of continuous positive airway pressure to enhance pre-oxygenation in morbidly obese women.
    Anaesthesia, 2001, Volume: 56, Issue:7

    Topics: Adult; Anesthesia, General; Apnea; Blood Pressure; Body Mass Index; Female; Heart Rate; Humans; Intu

2001
A comparison of recovery times between Althesin and methohexitone following anaesthesia for electro-convulsive therapy.
    Postgraduate medical journal, 1972, Volume: 48

    Topics: Adult; Aged; Anesthesia, Intravenous; Anesthetics; Apnea; Clinical Trials as Topic; Drug Interaction

1972
A clinical trial of apparatus for anaesthesia for domiciliary midwifery.
    British journal of anaesthesia, 1973, Volume: 45, Issue:11

    Topics: Adolescent; Adult; Anesthesia, Obstetrical; Apnea; Clinical Trials as Topic; Dreams; Female; Home Ca

1973
[Pharmacogenetic reaction to succinyldicholine: therapy of prolonged apnea].
    Medizinische Klinik, 1967, Oct-20, Volume: 62, Issue:42

    Topics: Adult; Anesthesia; Animals; Apnea; Child; Cholinesterases; Clinical Trials as Topic; Female; Humans;

1967
The interaction of suxamethonium with propanidid and thiopentone.
    British journal of anaesthesia, 1970, Volume: 42, Issue:7

    Topics: Adult; Age Factors; Apnea; Female; Humans; Male; Middle Aged; Muscular Diseases; Pain; Propanidid; S

1970

Other Studies

350 other studies available for succinylcholine and Apnea

ArticleYear
A prolonged paralysis with succinylcholine in pseudocholinesterase deficiency: an undesired effect.
    QJM : monthly journal of the Association of Physicians, 2022, 08-13, Volume: 115, Issue:8

    Topics: Apnea; Butyrylcholinesterase; Humans; Metabolism, Inborn Errors; Paralysis; Succinylcholine

2022
Pseudocholinesterase Deficiency Considerations: A Case Study.
    Anesthesia progress, 2020, 09-01, Volume: 67, Issue:3

    Topics: Apnea; Butyrylcholinesterase; Female; Humans; Metabolism, Inborn Errors; Mivacurium; Succinylcholine

2020
Timing of blood sampling for butyrylcholinesterase phenotyping in patients with prolonged neuromuscular block after mivacurium or suxamethonium.
    Acta anaesthesiologica Scandinavica, 2021, Volume: 65, Issue:2

    Topics: Apnea; Butyrylcholinesterase; Humans; Mivacurium; Neuromuscular Blockade; Succinylcholine

2021
Prolonged apnea after ECT in organophosphorus poisoning - the need to redefine norms.
    BMC psychiatry, 2021, 03-10, Volume: 21, Issue:1

    Topics: Apnea; Electroconvulsive Therapy; Female; Humans; Neuromuscular Depolarizing Agents; Organophosphate

2021
Phenotype and genotype characteristics of 58 patients showing a prolonged effect of succinylcholine: A four-year experience.
    Anaesthesia, critical care & pain medicine, 2021, Volume: 40, Issue:2

    Topics: Apnea; Genotype; Humans; Mutation; Phenotype; Succinylcholine

2021
Prolonged paralysis in a child with organophosphate pesticide poisoning.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2018, 05-25, Volume: 108, Issue:6

    Topics: Apnea; Atropine; Butyrylcholinesterase; Critical Care; Emergency Medical Services; Follow-Up Studies

2018
Reversal of succinylcholine induced apnea with an organophosphate scavenging recombinant butyrylcholinesterase.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Apnea; Butyrylcholinesterase; Catalysis; Guinea Pigs; Humans; Male; Mice; Recombinant Prote

2013
Patient information sheet for plasma cholinesterase deficiency.
    Anaesthesia, 2013, Volume: 68, Issue:10

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Documentation; Drug Hypersensitivity; Follow-Up Studi

2013
Rocuronium-sugammadex use in electroconvulsive therapy of patients with pseudocholinesterase enzyme deficiency.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:8

    Topics: Androstanols; Apnea; Butyrylcholinesterase; Contraindications; Electroconvulsive Therapy; gamma-Cycl

2013
[Residual relaxant block due to pseudocholinesterase deficiency - First manifestation in an elderly patient].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2014, Volume: 49, Issue:1

    Topics: Aged; Anesthesia Recovery Period; Anesthesia, General; Apnea; Butyrylcholinesterase; Humans; Intraop

2014
Use of neuromuscular monitoring to detect prolonged effect of succinylcholine or mivacurium: three case reports.
    Acta anaesthesiologica Scandinavica, 2014, Volume: 58, Issue:8

    Topics: Accelerometry; Aged; Antidotes; Apnea; Appendicitis; Butyrylcholinesterase; Cholecystectomy, Laparos

2014
Allergic reaction to suxamethonium during emergency caesarean section and pseudocholinesterase deficiency in the same patient.
    Wiener klinische Wochenschrift, 2014, Volume: 126, Issue:13-14

    Topics: Anesthesia, Obstetrical; Apnea; Butyrylcholinesterase; Cesarean Section; Diagnosis, Differential; Dr

2014
Characterization of a novel BCHE "silent" allele: point mutation (p.Val204Asp) causes loss of activity and prolonged apnea with suxamethonium.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Alleles; Apnea; Base Sequence; Biocatalysis; Butyrylcholinesterase; DNA Mutational Analysis; Family

2014
Premature awakening and underuse of neuromuscular monitoring in a registry of patients with butyrylcholinesterase deficiency.
    British journal of anaesthesia, 2015, Volume: 115 Suppl 1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apnea; Butyrylcholinesterase; Child; Child, Preschool; F

2015
Prolonged Apnea During Modified Electroconvulsive Therapy in a Patient of Suicidal Attempt by Organophosphorus Poisoning: A Case Report.
    The journal of ECT, 2016, Volume: 32, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Bipolar Disorder; Humans; Male; Neu

2016
[Prolonged neuromuscular block in a patient with butyrylcholinesterase deficiency].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2016, Volume: 23, Issue:5

    Topics: Adolescent; Apnea; Butyrylcholinesterase; Humans; Male; Metabolism, Inborn Errors; Neuromuscular Dep

2016
Fasciculations after succinylcholine and arterial oxygen tensions.
    British journal of anaesthesia, 2016, Volume: 116, Issue:5

    Topics: Apnea; Fasciculation; Humans; Oxygen; Rocuronium; Succinylcholine

2016
Unknown Pseudocholinesterase Deficiency in a Patient Undergoing TIVA with Planned Motor Evoked Potential Monitoring: A Case Report.
    AANA journal, 2016, Volume: 84, Issue:3

    Topics: Aged, 80 and over; Anesthesia, Intravenous; Apnea; Butyrylcholinesterase; Cervical Vertebrae; Diskec

2016
Electroconvulsive Therapy Considerations for Transgendered Patients.
    The journal of ECT, 2017, Volume: 33, Issue:2

    Topics: Adult; Androstanols; Apnea; Butyrylcholinesterase; Depressive Disorder, Treatment-Resistant; Drug In

2017
The relation of plasma cholinesterases to response to clinical doses of succinylcholine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2008, Volume: 55, Issue:12

    Topics: Apnea; Cholinesterases; Dose-Response Relationship, Drug; Humans; Male; Neuromuscular Depolarizing A

2008
General medicine and surgery for dental practitioners. Part 2--metabolic disorders.
    British dental journal, 2010, May-08, Volume: 208, Issue:9

    Topics: Amyloidosis; Anesthetics, Local; Apnea; Carbohydrate Metabolism, Inborn Errors; Dental Care for Chro

2010
Butyrylcholinesterase gene mutations in patients with prolonged apnea after succinylcholine for electroconvulsive therapy.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:1

    Topics: Adult; Aged; Anesthesia; Anesthesia Recovery Period; Apnea; Butyrylcholinesterase; Dose-Response Rel

2011
Desaturation during rapid sequence induction of anaesthesia.
    Anaesthesia, 2010, Volume: 65, Issue:9

    Topics: Androstanols; Apnea; Humans; Neuromuscular Depolarizing Agents; Neuromuscular Nondepolarizing Agents

2010
Prolonged neuromuscular paralysis following rapid-sequence intubation with succinylcholine.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:4

    Topics: Apnea; Butyrylcholinesterase; Female; Humans; Intubation, Intratracheal; Metabolism, Inborn Errors;

2011
[Apnea after general anesthesia for revision of uterus in parturient with K-variant of the butyrylcholinesterase enzyme (BChE)].
    Harefuah, 2012, Volume: 151, Issue:7

    Topics: Adult; Anesthesia, General; Apnea; Butyrylcholinesterase; Female; Humans; Labor, Obstetric; Neuromus

2012
Prolonged apnea following succinylcholine administration in undiagnosed acute organophosphate poisoning.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:8

    Topics: Acute Disease; Apnea; Diagnostic Errors; Dichlorvos; Food Contamination; Humans; Infant; Insecticide

2002
Rapid identification of atypical variant of plasma butyrylcholinesterase by PCR.
    Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:8

    Topics: Apnea; Butyrylcholinesterase; Female; Genetic Testing; Genetic Variation; Heterozygote; Homozygote;

2002
[Emergency from anesthesia in small children. From laryngospasm to prolonged apnea].
    Der Anaesthesist, 2003, Volume: 52, Issue:2

    Topics: Airway Obstruction; Anesthesia; Apnea; Butyrylcholinesterase; Child, Preschool; Emergency Medical Se

2003
Assay using succinyldithiocholine as substrate: the method of choice for the measurement of cholinesterase catalytic activity in serum to diagnose succinyldicholine sensitivity.
    Clinical chemistry and laboratory medicine, 2003, Volume: 41, Issue:3

    Topics: Anesthetics, Local; Apnea; Butyrylthiocholine; Cariostatic Agents; Catalysis; Cholinesterase Inhibit

2003
Fresh frozen plasma for succinylcholine apnoea--time to reconsider?
    Anaesthesia, 2003, Volume: 58, Issue:8

    Topics: Adult; Apnea; Cholinesterases; Female; Humans; Neuromuscular Depolarizing Agents; Plasma; Succinylch

2003
Butyrylcholinesterase (BCHE) genotyping for post-succinylcholine apnea in an Australian population.
    Clinical chemistry, 2003, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics; Apnea; Australia; Butyrylcholinesterase; Ch

2003
Prolonged apnoea following injection of succinyldicholine.
    Lancet (London, England), 1953, Nov-21, Volume: 265, Issue:6795

    Topics: Apnea; Humans; Injections; Succinylcholine

1953
Bronchial neoplasm with myasthenia; prolonged apnoea after administration of succinylcholine.
    Lancet (London, England), 1953, Dec-19, Volume: 265, Issue:6799

    Topics: Apnea; Bronchial Neoplasms; Disease; Humans; Lung Neoplasms; Muscle Weakness; Muscles; Muscular Dise

1953
[Case of prolonged apnea after succinylcholine administration].
    Svenska lakartidningen, 1953, Oct-16, Volume: 50, Issue:42

    Topics: Apnea; Delivery, Obstetric; Female; Humans; Jaundice; Obstetric Labor Complications; Pregnancy; Succ

1953
Prolonged scoline apnoea treated by blood transfusion.
    Anaesthesia, 1954, Volume: 9, Issue:1

    Topics: Apnea; Blood Transfusion; Humans; Succinylcholine

1954
Nine hours' apnoea following succinylcholine.
    Anaesthesia, 1954, Volume: 9, Issue:1

    Topics: Apnea; Humans; Succinylcholine

1954
Suxamethonium sensitivity in health and disease; a clinical evaluation of pseudo-cholinesterase levels.
    British medical journal, 1954, Jul-03, Volume: 2, Issue:4878

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Drug Hypersensitivity; Health; Humans; Metabolism, In

1954
Prolonged apnoea after suxamethonium; a case study of pseudocholinesterase.
    Lancet (London, England), 1954, Aug-21, Volume: 267, Issue:6834

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Electroconvulsive Therapy; Humans; Succinylcholine

1954
[Case of prolonged apnea due to celocurin].
    Svenska lakartidningen, 1954, Jul-16, Volume: 51, Issue:29

    Topics: Apnea; Humans; Succinylcholine

1954
[Apnea caused by succinylcholine and its relation to serum cholinesterase].
    Nordisk medicin, 1954, Sep-02, Volume: 52, Issue:36

    Topics: Apnea; Blood; Cholinesterases; Humans; Succinylcholine

1954
Prolonged apnoea following suxamethonium chloride.
    British journal of anaesthesia, 1954, Volume: 26, Issue:6

    Topics: Apnea; Humans; Succinylcholine

1954
Prolonged apnoea after suxamethonium in man.
    British journal of anaesthesia, 1955, Volume: 27, Issue:1

    Topics: Apnea; Humans; Male; Succinylcholine

1955
Dual action of suxamethonium chloride.
    British journal of anaesthesia, 1956, Volume: 28, Issue:4

    Topics: Apnea; Humans; Neostigmine; Succinylcholine

1956
Prolonged succinylcholine apnoea reversed by prostigmin.
    Canadian Medical Association journal, 1956, Jul-01, Volume: 75, Issue:1

    Topics: Apnea; Humans; Neostigmine; Succinylcholine

1956
[beta-Diethylamino-ethyl-diphenylpropyl acetate (SKF 525 A); potentiation of the effects of succinylcholine; contribution to the study of the mechanism of prolonged succinylcholine-induced apnea].
    Rendiconti - Istituto superiore di sanita, 1956, Volume: 19, Issue:9

    Topics: Acetates; Apnea; Fatty Acids; Humans; Proadifen; Succinylcholine

1956
[beta-Diethylamino-ethyl-diphenylpropyl acetate (SKF 525 A); potentiation of the effects of succinylcholine; contribution to the study of the mechanism of prolonged succinylcholine-induced apnea].
    Rendiconti - Istituto superiore di sanita, 1956, Volume: 19, Issue:9

    Topics: Acetates; Apnea; Fatty Acids; Humans; Proadifen; Succinylcholine

1956
[beta-Diethylamino-ethyl-diphenylpropyl acetate (SKF 525 A); potentiation of the effects of succinylcholine; contribution to the study of the mechanism of prolonged succinylcholine-induced apnea].
    Rendiconti - Istituto superiore di sanita, 1956, Volume: 19, Issue:9

    Topics: Acetates; Apnea; Fatty Acids; Humans; Proadifen; Succinylcholine

1956
[beta-Diethylamino-ethyl-diphenylpropyl acetate (SKF 525 A); potentiation of the effects of succinylcholine; contribution to the study of the mechanism of prolonged succinylcholine-induced apnea].
    Rendiconti - Istituto superiore di sanita, 1956, Volume: 19, Issue:9

    Topics: Acetates; Apnea; Fatty Acids; Humans; Proadifen; Succinylcholine

1956
The relation between dose of succinylcholine and duration of apnea in man.
    The Journal of pharmacology and experimental therapeutics, 1957, Volume: 120, Issue:2

    Topics: Apnea; Humans; Male; Succinylcholine

1957
Persistent apnoea associated with succinylcholine chloride.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1957, Nov-23, Volume: 31, Issue:47

    Topics: Apnea; Humans; Succinylcholine

1957
[Duration apnea due to succinylcholine in relation to administration of plasma].
    Bollettino della Societa italiana di biologia sperimentale, 1958, Sep-15, Volume: 34, Issue:17

    Topics: Apnea; Blood Transfusion; Humans; Plasma; Succinylcholine

1958
Sensitivity to suxamethonium; apnoea in two brothers.
    Lancet (London, England), 1958, Nov-08, Volume: 2, Issue:7054

    Topics: Apnea; Humans; Male; Siblings; Succinylcholine

1958
Modified ECT using succinylcholine followed by prolonged apnea.
    The American journal of psychiatry, 1959, Volume: 115, Issue:9

    Topics: Apnea; Electroconvulsive Therapy; Humans; Succinylcholine

1959
Prolonged apnoea following E.C.T. modified by suxethonium (brevidil E).
    The Journal of mental science, 1959, Volume: 105, Issue:439

    Topics: Apnea; Convulsive Therapy; Electroconvulsive Therapy; Humans; Muscle Relaxants, Central; Succinylcho

1959
[Findings on prolonged apnea caused by succinylcholine: effect of the nature of the anesthetic].
    Rassegna clinico-scientifica, 1959, Volume: 35, Issue:5

    Topics: Anesthesia; Anesthetics; Apnea; Humans; Succinylcholine

1959
Prolonged apnoea after suxamethonium increased intracranial pressure.
    British journal of anaesthesia, 1961, Volume: 33

    Topics: Anesthesia; Apnea; Humans; Intracranial Hypertension; Intracranial Pressure; Succinylcholine

1961
[Prolonged apnea after succinylcholine chloride].
    Ugeskrift for laeger, 1961, Jul-28, Volume: 123

    Topics: Apnea; Humans; Succinylcholine

1961
[Prolonged apnea caused by succinylcholine and treatment by transfusion].
    L'union medicale du Canada, 1961, Volume: 90

    Topics: Apnea; Blood Transfusion; Humans; Platelet Transfusion; Succinylcholine

1961
[On prolonged apnea from succinyl-choline].
    Minerva anestesiologica, 1961, Volume: 27

    Topics: Apnea; Humans; Succinylcholine

1961
Prolonged apnoea following the use of suxamethonium. A case presenting some unusual features.
    Anaesthesia, 1960, Volume: 15

    Topics: Anesthesia; Apnea; Cardiovascular Agents; Humans; Iatrogenic Disease; Muscle Relaxants, Central; Suc

1960
[Succinyl-bis-choline chloride drop infusion for the prevention of prolonged apnoe or paralysis].
    Orvosi hetilap, 1959, Sep-20, Volume: 100

    Topics: Apnea; Biomedical Research; Choline; Humans; Paralysis; Succinylcholine; Surgical Procedures, Operat

1959
[Late recurarization during the use of Dilitin].
    Vestnik khirurgii imeni I. I. Grekova, 1961, Volume: 87

    Topics: Anesthesia; Anesthesia, General; Anesthesiology; Apnea; Humans; Succinylcholine

1961
Prolonged apnoea due to suxamethonium.
    British journal of anaesthesia, 1961, Volume: 33

    Topics: Apnea; Humans; Succinylcholine

1961
[Practical importance of plasma cholinesterase determination and its atypical behavior in relation to succinylbischoline].
    Der Anaesthesist, 1962, Volume: 11

    Topics: Apnea; Cholinesterases; Humans; Succinylcholine

1962
Prolonged apnea following the use of succinylcholine.
    Acta anaesthesiologica Belgica, 1963, Volume: 14

    Topics: Apnea; Humans; Parathion; Succinylcholine

1963
Prolonged respiratory depression caused by drug combinations. Muscle relaxants and intraperitoneal antibiotics as etiologic agents.
    JAMA, 1963, Feb-23, Volume: 183

    Topics: Anti-Bacterial Agents; Apnea; Drug Combinations; Neomycin; Respiratory Insufficiency; Streptomycin;

1963
[On 3 cases of apnea caused by succinylcholine].
    Rassegna internazionale di clinica e terapia, 1963, Jan-15, Volume: 43

    Topics: Adjuvants, Anesthesia; Apnea; Calcium; Calcium, Dietary; Cholinesterases; Humans; Succinylcholine

1963
Prolonged apnoea after intermittent intramuscular suxamethonium in a neonate.
    British journal of anaesthesia, 1962, Volume: 34

    Topics: Apnea; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Succinylcholine

1962
An investigation of a new aversive conditioning treatment for alcoholism.
    Quarterly journal of studies on alcohol, 1963, Volume: 24

    Topics: Alcoholism; Apnea; Conditioning, Classical; Conditioning, Psychological; Humans; Reflex; Succinylcho

1963
[On the side-effects of succinyl-bis-choline, especially on prolonged apnea. Critical remarks based on 1200 intubation anesthetics with succinvl-bis-choline].
    Arztliche Forschung, 1963, Feb-10, Volume: 17

    Topics: Anesthetics; Apnea; Choline; Humans; Intubation; Succinylcholine

1963
[On the problem of prolonged relaxation with short-acting muscle relaxants].
    Der Anaesthesist, 1963, Volume: 12

    Topics: Apnea; Cardiovascular Agents; Humans; Succinylcholine

1963
[STUDIES ON THE DIFFERENTIATION OF THE TYPE OF NEUROMUSCULAR BLOCK].
    Tohoku igaku zasshi, 1962, Volume: 66

    Topics: Anesthesia; Anesthesia, General; Anesthesiology; Animals; Apnea; Decamethonium Compounds; Dogs; Elec

1962
THE MISMANAGEMENT OF SUXAMETHONIUM APNOEA.
    British journal of anaesthesia, 1963, Volume: 35

    Topics: Apnea; Humans; Succinylcholine; Toxicology

1963
FAMILIAL SENSITIVITY TO SUXAMETHONIUM DUE TO ATYPICAL PSEUDOCHOLINESTERASE.
    British medical journal, 1964, Jan-18, Volume: 1, Issue:5376

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Genetics, Medical; Geriatrics; Humans; Succinylcholin

1964
SUXAMETHONIUM APNOEA.
    Lancet (London, England), 1964, Jan-18, Volume: 1, Issue:7325

    Topics: Apnea; Succinylcholine

1964
SUXAMETHONIUM SENSITIVITY.
    British medical journal, 1964, Feb-22, Volume: 1, Issue:5381

    Topics: Apnea; Blood; Butyrylcholinesterase; Cholinesterases; Drug Hypersensitivity; Fluorides; Genetics, Me

1964
[GENETICS AND BIOCHEMISTRY OF PSEUDOCHOLINESTERASES].
    Deutsche medizinische Wochenschrift (1946), 1963, Dec-27, Volume: 88

    Topics: Apnea; Biochemical Phenomena; Biochemistry; Biological Evolution; Butyrylcholinesterase; Cholinester

1963
CARDIAC ARREST (WITH APNOEA) AFTER E.C.T.
    The British journal of psychiatry : the journal of mental science, 1964, Volume: 110

    Topics: Apnea; Electroconvulsive Therapy; Heart Arrest; Humans; Muscle Relaxants, Central; Succinylcholine;

1964
[EXPERIMENTAL STUDIES ON A FORM OF RESTING TREMOR IN THE EXTREMITIES OF HEALTHY DOGS].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1964, Jan-30, Volume: 278

    Topics: Apnea; Dogs; Electrocardiography; Electroencephalography; Electromyography; Extremities; Heart Arres

1964
APNEA DUE TO INHERITANCE OF ATYPICAL PSEUDOCHOLINESTERASE.
    Canadian Medical Association journal, 1964, May-09, Volume: 90

    Topics: Abscess; Anesthesia; Anesthesia, General; Anesthesiology; Apnea; Butyrylcholinesterase; Cholinestera

1964
[ON A CASE OF PROLONGED APNEA CAUSED BY SUCCINYLCHOLINE].
    L' Arcispedale S. Anna di Ferrara, 1964, Volume: 17

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, General; Anesthesiology; Apnea; Cerebral Angiography;

1964
CLINICAL STUDIES OF INDUCTION AGENTS. XI. THE INFLUENCE OF SOME INTRAVENOUS ANAESTHETICS ON THE RESPIRATORY EFFECTS AND SEQUELAE OF SUXAMETHONIUM.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Anesthesia; Anesthesia, Intravenous; Anesthetics; Anesthetics, Intravenous; Apnea; Barbiturates; Hyp

1964
A COMPLICATION OF THE USE OF SUXAMETHONIUM "EXTENSION" BY TETRAHYDROAMINACRINE.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Adolescent; Apnea; Appendectomy; Atropine; Bradycardia; Central Nervous System Stimulants; Humans; H

1964
ENZYMES AND DRUG SENSITIVITY. THE GENETICS OF SERUM CHOLINESTERASE 'DEFICIENCY' IN RELATION TO SUXAMETHONIUM APNOEA.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Apnea; Blood; Cholinesterases; Drug Tolerance; Genetics, Medical; Humans; Metabolism, Inborn Errors;

1964
[OBSERVATIONS ON THE USE OF MUSCLE RELAXANTS IN PATIENTS WITH ADRENAL CORTEX HYPERFUNCTION].
    Minerva anestesiologica, 1964, Volume: 30

    Topics: Adrenal Cortex; Adrenalectomy; Adrenocortical Hyperfunction; Anesthesia; Apnea; Cushing Syndrome; Hu

1964
PROBLEMS IN PAEDIATRIC ANAESTHESIA.
    The Medical journal of Australia, 1964, Oct-24, Volume: 2

    Topics: Anesthesia; Anesthesiology; Apnea; Arrhythmias, Cardiac; Bradycardia; Child; Humans; Hypothermia; In

1964
PHARMACOGENETICS IN PRE-ECT MEDICATION.
    The American journal of psychiatry, 1964, Volume: 121

    Topics: Antidotes; Apnea; Blood; Blood Transfusion; Cholinesterases; Electroconvulsive Therapy; Genetics, Me

1964
THE PSEUDOCHOLINESTERASE VARIANTS: ESTERASE LEVELS AND INCREASED RESISTANCE TO FLUORIDE.
    Acta genetica et statistica medica, 1964, Volume: 14

    Topics: Apnea; Biochemical Phenomena; Blood; Butyrylcholinesterase; Cholinesterases; Esterases; Fluorides; G

1964
ON NOMENCLATURE OF PSEUDOCHOLINESTERASE POLYMORPHISM.
    Acta genetica et statistica medica, 1964, Volume: 14

    Topics: Apnea; Blood; Butyrylcholinesterase; Cholinesterases; Genetics, Medical; Humans; Polymorphism, Genet

1964
[ON 2 CASES OF PROLONGED APNEA DUE TO SUCCINYLCHOLINE].
    La Clinica ostetrica e ginecologica, 1964, Volume: 66

    Topics: Apnea; Succinylcholine; Toxicology

1964
CARBON DIOXIDE ELIMINATION DURING INSUFFLATION ANAESTHESIA.
    British journal of anaesthesia, 1965, Volume: 37

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesiology; Apnea; Bronchoscopy; Carbon Dioxide; Hu

1965
PROCEDURE FOR DETECTING A TYPICAL SERUM CHOLINESTERASE USING O-NITROPHENYLBUTYRATE AS SUBSTRATE.
    Clinical chemistry, 1965, Volume: 11

    Topics: Apnea; Biomedical Research; Blood Chemical Analysis; Cholinesterases; Genetics, Medical; Humans; Mol

1965
DETECTION OF ATYPICAL CHOLINESTERASE BY ELECTROPHORESIS.
    Archives of neurology, 1965, Volume: 13

    Topics: Apnea; Blood; Chemistry Techniques, Analytical; Cholinesterases; Drug Hypersensitivity; Electrophore

1965
[ON THE USE OF SUCCINYLCHOLINE AS A MUSCLE RELAXANT].
    Khirurgiia, 1965, Volume: 18

    Topics: Apnea; Child; Humans; Infant; Muscle Relaxants, Central; Succinylcholine; Toxicology

1965
Suxamethonium apnoea in an infant; expression of familial pseudocholinesterase deficiency in three generations.
    British medical journal, 1960, Jan-16, Volume: 1, Issue:5167

    Topics: Apnea; Bis-Trimethylammonium Compounds; Butyrylcholinesterase; Child; Cholinesterases; Humans; Infan

1960
[Studies on the duration of apnea after succinylcholine in ventilation with intermittent positive pressure or with positive-negative pressure with reference to the Hering-Breuer reflex].
    Der Anaesthesist, 1960, Volume: 9

    Topics: Anesthesia; Anesthesiology; Apnea; Humans; Reflex; Respiration; Succinylcholine

1960
Plasma cholinesterase and the duration of succinylcholine-induced apnea.
    Journal of oral surgery, anesthesia, and hospital dental service, 1960, Volume: 18

    Topics: Apnea; Cholinesterases; Succinylcholine

1960
Prolonged apnea after administration of succinylcholine.
    The New England journal of medicine, 1960, Jun-02, Volume: 262

    Topics: Apnea; Humans; Succinylcholine

1960
[On prolonged apnea caused by the use of Listenol].
    Vestnik khirurgii imeni I. I. Grekova, 1962, Volume: 89

    Topics: Apnea; Humans; Succinylcholine

1962
Apnoea due to suxamethonium associated with familial pseudocholinesterase deficiency.
    Lancet (London, England), 1962, Apr-21, Volume: 1, Issue:7234

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Humans; Metabolism, Inborn Errors; Muscular Diseases;

1962
Prolonged succinylcholine apnoea resulting from acquired deficiency of plasma cholinesterase.
    Anaesthesia, 2003, Volume: 58, Issue:11

    Topics: Aged; Antineoplastic Agents, Alkylating; Apnea; Cholinesterases; Cyclophosphamide; Humans; Male; Neu

2003
The management of succinylcholine apnoea.
    Anaesthesia, 2003, Volume: 58, Issue:11

    Topics: Apnea; Blood-Borne Pathogens; Humans; Neuromuscular Depolarizing Agents; Succinylcholine

2003
Fresh frozen plasma for succinylcholine apnoea.
    Anaesthesia, 2004, Volume: 59, Issue:1

    Topics: Apnea; Humans; Neuromuscular Depolarizing Agents; Plasma; Succinylcholine

2004
Accidental administration of succinylcholine for the treatment of hypotension in a labouring parturient.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:8

    Topics: Adult; Apnea; Color; Drug Compounding; Drug Labeling; Female; Humans; Hypotension; Labor, Obstetric;

2004
[Prolonged succinylcholine-induced apnoea associated with cholinesterase silent plasma variant].
    Annales francaises d'anesthesie et de reanimation, 2005, Volume: 24, Issue:4

    Topics: Aged; Apnea; Butyrylcholinesterase; Cholinesterases; Humans; Male; Neuromuscular Depolarizing Agents

2005
Use of remifentanil for tracheal intubation for caesarean section in a patient with suxamethonium apnoea.
    Anaesthesia, 2005, Volume: 60, Issue:10

    Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anesthesia, Obstetrical; Apnea; Cesarean Section; Co

2005
[Accidental use of suxamethonium for general anesthesia in a patient with hereditary hypocholinesterasemia that was not recognized preoperatively].
    Masui. The Japanese journal of anesthesiology, 2006, Volume: 55, Issue:8

    Topics: Adult; Anesthesia, General; Apnea; Cesarean Section; Cholinesterases; Chronic Disease; Colectomy; Co

2006
Molecular basis of succinylcholine sensitivity in a prairie Hutterite kindred and genetic characterization of the region containing the BCHE gene.
    Molecular genetics and metabolism, 2007, Volume: 90, Issue:2

    Topics: Apnea; Butyrylcholinesterase; Canada; Dibucaine; Ethnicity; Female; Genetics, Population; Humans; Ma

2007
Determination of butyrylcholinesterase (BChE) phenotypes to predict the risk of prolonged apnea in persons receiving succinylcholine in the healthy population of western Iran.
    Clinical biochemistry, 2007, Volume: 40, Issue:9-10

    Topics: Adult; Apnea; Butyrylcholinesterase; Female; Humans; Iran; Male; Risk; Succinylcholine

2007
Testing for suxamethonium apnoea.
    British journal of hospital medicine (London, England : 2005), 2007, Volume: 68, Issue:5

    Topics: Apnea; Humans; Neuromuscular Depolarizing Agents; Succinylcholine

2007
[Prolonged apnea after succinyldicholine].
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 25

    Topics: Apnea; Cholinesterases; Humans; Succinylcholine

1966
Effect of carbon dioxide on the cortical seizure threshold to lidocaine.
    Experimental neurology, 1967, Volume: 17, Issue:2

    Topics: Amygdala; Animals; Apnea; Blood Pressure Determination; Brain; Carbon Dioxide; Cats; Cerebral Cortex

1967
Prolonged postoperative apnea with pseudocholinesterase deficiency.
    The American review of respiratory disease, 1967, Volume: 96, Issue:3

    Topics: Adult; Anesthesia, General; Apnea; Bronchography; Cholinesterases; Deficiency Diseases; Female; Huma

1967
Evaluation of an aversive technique as a treatment for alcoholism. Controlled trial with succinylcholine-induced apnea.
    Quarterly journal of studies on alcohol, 1967, Volume: 28, Issue:3

    Topics: Alcoholism; Apnea; Conditioning, Classical; Conditioning, Psychological; Follow-Up Studies; Humans;

1967
The clinical use of muscle relaxants.
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1967, Volume: 23, Issue:1

    Topics: Anesthesia; Apnea; Decamethonium Compounds; Drug Synergism; Gallamine Triethiodide; Humans; Muscles;

1967
Potentiation of succinylcholine by organophosphate compounds in horses.
    Journal of the American Veterinary Medical Association, 1967, Jul-01, Volume: 151, Issue:1

    Topics: Animals; Anthelmintics; Apnea; Cholinesterases; Drug Synergism; Gluconates; Horse Diseases; Horses;

1967
Pre-oxygenation and thiopentone-suxamethonium induction.
    British journal of anaesthesia, 1967, Volume: 39, Issue:10

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Endotracheal; Apnea; Carbon Dioxide; Female; Humans;

1967
Suxamethonium apnoea.
    British journal of anaesthesia, 1967, Volume: 39, Issue:11

    Topics: Apnea; Humans; Succinylcholine

1967
A review of succinylcholine-induced apnea.
    AANA journal, 1982, Volume: 50, Issue:4

    Topics: Apnea; Cholinesterases; Drug Interactions; Female; Humans; Postoperative Complications; Pregnancy; R

1982
A new succinylcholine-based assay of plasma cholinesterase.
    Clinical chemistry, 1984, Volume: 30, Issue:2

    Topics: Alcohol Oxidoreductases; Apnea; Choline; Cholinesterase Inhibitors; Cholinesterases; Humans; Hydroge

1984
Frequencies of atypical serum cholinesterase in a mixed population of northeastern Brazil.
    Human heredity, 1984, Volume: 34, Issue:6

    Topics: Alleles; Apnea; Black People; Brazil; Cholinesterases; Female; Gene Frequency; Humans; Indians, Sout

1984
A family with the silent cholinesterase gene.
    Anaesthesia and intensive care, 1983, Volume: 11, Issue:3

    Topics: Adult; Alleles; Anesthesia, Endotracheal; Apnea; Cholinesterases; Female; Heterozygote; Humans; Meta

1983
Succinylcholine apnoea: attempted reversal with anticholinesterases.
    Canadian Anaesthetists' Society journal, 1983, Volume: 30, Issue:5

    Topics: Adult; Apnea; Cholinesterase Inhibitors; Cholinesterases; Female; Heterozygote; Humans; Succinylchol

1983
Scoline apnoea.
    Anaesthesia and intensive care, 1984, Volume: 12, Issue:1

    Topics: Aged; Apnea; Female; Humans; Succinylcholine

1984
Prolonged apnea after orthognathic surgery due to atypical cholinesterase.
    International journal of oral surgery, 1981, Volume: 10, Issue:5

    Topics: Adult; Anesthesia, Dental; Anesthesia, Intravenous; Apnea; Cholinesterases; Female; Humans; Mandible

1981
Eye drops and apnea.
    Canadian Medical Association journal, 1983, Apr-15, Volume: 128, Issue:8

    Topics: Anesthesia; Apnea; Drug Interactions; Echothiophate Iodide; Humans; Ophthalmic Solutions; Respiratio

1983
Heterozygotes for atypical cholinesterase.
    British journal of anaesthesia, 1983, Volume: 55, Issue:4

    Topics: Adolescent; Adult; Aged; Apnea; Cholinesterases; Electroconvulsive Therapy; Female; Heterozygote; Hu

1983
Prolonged neuromuscular blockade following succinylcholine in a patient homozygous for the silent gene.
    Anesthesiology, 1983, Volume: 59, Issue:1

    Topics: Adult; Apnea; Cholinesterases; Electric Stimulation; Female; Genotype; Homozygote; Humans; Muscle Co

1983
Suxamethonium apnoea associated with pregnancy and liver dysfunction in a treated cretin.
    Anaesthesia, 1983, Volume: 38, Issue:6

    Topics: Adult; Anesthesia, Obstetrical; Apnea; Cesarean Section; Cholinesterases; Congenital Hypothyroidism;

1983
Prolonged succinylcholine-induced apnea caused by atypical cholinesterase: report of case.
    Journal of oral surgery (American Dental Association : 1965), 1980, Volume: 38, Issue:5

    Topics: Adult; Apnea; Cholinesterase Inhibitors; Cholinesterases; Facial Injuries; Humans; Male; Mandibular

1980
Apnoea following suxamethonium: the genetic study of four generations of a family.
    Journal of medical genetics, 1982, Volume: 19, Issue:1

    Topics: Adult; Apnea; Child; Cholinesterases; Female; Humans; Male; Middle Aged; Pedigree; Succinylcholine

1982
Routine induction of anaesthesia with thiopental and suxamethonium: apnoea without ventilation?
    Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:1

    Topics: Anesthesia, General; Apnea; Humans; Intubation, Intratracheal; Middle Aged; Oxygen Inhalation Therap

1982
[Succinylcholine apnea].
    Revista espanola de anestesiologia y reanimacion, 1982, Volume: 29, Issue:1

    Topics: Apnea; Cholinesterases; Humans; Succinylcholine

1982
[Succinylcholinic apnoea, study of a thirteen-member family (author's transl)].
    Revista espanola de anestesiologia y reanimacion, 1982, Volume: 29, Issue:1

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Apnea; Child; Child, Preschool; Cholinesterases; Female; F

1982
Prolonged postoperative apnea complicating gynecologic surgery; atypical cholinesterase and myasthenia gravis.
    American journal of obstetrics and gynecology, 1982, May-01, Volume: 143, Issue:1

    Topics: Adult; Apnea; Cholinesterases; Female; Genital Diseases, Female; Humans; Infant, Newborn; Middle Age

1982
Reduced plasma cholinesterase following haemodilutional cardiopulmonary bypass.
    Anaesthesia, 1982, Volume: 37, Issue:3

    Topics: Aged; Apnea; Cardiopulmonary Bypass; Cholinesterases; Hemodilution; Humans; Male; Succinylcholine

1982
Prolonged postoperative succinylcholine-induced apnea with pseudocholinesterase deficiency.
    Journal of the Tennessee Medical Association, 1982, Volume: 75, Issue:8

    Topics: Adult; Apnea; Butyrylcholinesterase; Cholinesterases; Female; Humans; Postoperative Complications; S

1982
Prolonged apnoea after suxamethonium in a Malaysian patient due to silent plasma cholinesterase--first case report.
    The Medical journal of Malaysia, 1982, Volume: 37, Issue:2

    Topics: Apnea; Cholinesterases; Humans; Malaysia; Male; Middle Aged; Phenotype; Succinylcholine

1982
Suxamethonium sensitivity -- yet another case.
    The Medical journal of Malaysia, 1982, Volume: 37, Issue:4

    Topics: Adult; Apnea; Cholinesterases; Drug Hypersensitivity; Female; Humans; Male; Succinylcholine

1982
Plasma cholinesterase activity in bank blood.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:3

    Topics: Adult; Anesthesia, General; Apnea; Blood Banks; Blood Preservation; Blood Transfusion; Cholinesteras

1980
A family segregating for E1j and E1k at cholinesterase locus 1.
    Journal of medical genetics, 1980, Volume: 17, Issue:6

    Topics: Adolescent; Alleles; Apnea; Female; Humans; Male; Pedigree; Phenotype; Succinylcholine

1980
[Blood and plasma transfusion in the treatment of prolonged succinylcholine apnea].
    Revista espanola de anestesiologia y reanimacion, 1981, Volume: 28, Issue:1

    Topics: Adult; Aged; Apnea; Blood Transfusion; Butyrylcholinesterase; Humans; Middle Aged; Plasma; Succinylc

1981
Haemodynamic and neurological responses of ventilated and apnoeic calves to succinyldicholine.
    Journal of the South African Veterinary Association, 1981, Volume: 52, Issue:4

    Topics: Animals; Apnea; Catecholamines; Cattle; Cattle Diseases; Electroencephalography; Hemodynamics; Male;

1981
Patient sensitivity to suxamethonium due to abnormal enzyme--a case report.
    The Ceylon medical journal, 1981, Volume: 26, Issue:4

    Topics: Adult; Anesthesia, Obstetrical; Apnea; Butyrylcholinesterase; Cesarean Section; Cholinesterases; Fem

1981
Pseudocholinesterase levels and rates of chloroprocaine hydrolysis in patients receiving adequate doses of phospholine iodide.
    Anesthesiology, 1980, Volume: 52, Issue:5

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Echothiophate Iodide; Humans; Procaine; Succinylcholi

1980
Suxamethonium apnoea associated with plasmaphoresis.
    Anaesthesia, 1980, Volume: 35, Issue:2

    Topics: Adult; Anesthesia, Obstetrical; Apnea; Cesarean Section; Cholinesterases; Female; Humans; Plasmapher

1980
Propanidid--suxamethonium apnea in bilharzial patients.
    Middle East journal of anaesthesiology, 1980, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Anesthesia; Apnea; Cholinesterases; Drug Synergism; Female; Humans; Liver Disease

1980
[A rare case of silent cholinesterase genetic variant (author's transl)].
    Medicina clinica, 1980, Oct-25, Volume: 75, Issue:7

    Topics: Adolescent; Alleles; Anesthesia, General; Apnea; Cholinesterase Inhibitors; Cholinesterases; Heteroz

1980
Plasma cholinesterase changes during pregnancy. Their interpretation as a cause of suxamethonium-induced apnoea.
    Anaesthesia, 1980, Jul-07, Volume: 35, Issue:7

    Topics: Adolescent; Adult; Apnea; Cholinesterases; Female; Genotype; Humans; Postpartum Period; Pregnancy; P

1980
Correlation of succinylcholine duration of action with plasma cholinesterase activity in subjects with the genotypically normal enzyme.
    Anesthesiology, 1980, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Apnea; Cholinesterases; Female; Humans; Male; Middle Aged; Neuromuscular Bl

1980
Plasma cholinesterase deficiency in a neonate: a follow-up.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:4

    Topics: Apnea; Child, Preschool; Cholinesterases; Dibucaine; Female; Follow-Up Studies; Humans; Infant, Newb

1995
Plasma cholinesterase activity in infants.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:7

    Topics: Apnea; Cholinesterases; Humans; Infant, Newborn; Neuromuscular Blocking Agents; Succinylcholine

1994
Suxamethonium apnoea and the isolated leg.
    Anaesthesia, 1994, Volume: 49, Issue:4

    Topics: Adult; Anesthesia, General; Apnea; Butyrylcholinesterase; Electric Stimulation; Genotype; Humans; Kn

1994
Plasma cholinesterase deficiency in a premature neonate.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:3

    Topics: Anesthesia, Intravenous; Apnea; Cholinesterases; Humans; Infant, Newborn; Infant, Premature; Infant,

1994
Sedation for non-invasive procedures: a potential hazard.
    Irish journal of medical science, 1994, Volume: 163, Issue:4

    Topics: Aged; Aged, 80 and over; Apnea; Conscious Sedation; Female; Humans; Medication Errors; Pacemaker, Ar

1994
Suxamethonium-induced prolonged apnoea in a premature neonate.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:2

    Topics: Anesthesia, Intravenous; Apnea; Cerebrospinal Fluid Shunts; Cholinesterases; Homozygote; Humans; Hyd

1994
Suxamethonium in the deadspace of an adult's indwelling intravenous cannula.
    Anaesthesia, 1993, Volume: 48, Issue:9

    Topics: Adult; Apnea; Catheters, Indwelling; Fasciculation; Humans; Male; Respiratory Dead Space; Succinylch

1993
Fresh frozen plasma and edrophonium in a patient with a plasma cholinesterase deficiency.
    Anaesthesia, 1993, Volume: 48, Issue:6

    Topics: Adult; Apnea; Cholinesterases; Edrophonium; Female; Humans; Monitoring, Physiologic; Neuromuscular J

1993
Plasma cholinesterase deficiency in a neonate.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:6

    Topics: Apnea; Cholinesterases; Humans; Infant, Newborn; Injections, Intravenous; Succinylcholine; Time Fact

1993
Respiratory arrest in two children following postoperative flushing of suxamethonium from the deadspace of intravenous cannulae.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:1

    Topics: Apnea; Catheterization; Child, Preschool; Humans; Male; Neuromuscular Depolarizing Agents; Postopera

1996
[Prolonged apnea after suxamethonium administration during staphylococcal toxic shock].
    Annales francaises d'anesthesie et de reanimation, 1996, Volume: 15, Issue:2

    Topics: Adult; Apnea; Cholinesterases; Humans; Male; Neuromuscular Depolarizing Agents; Shock, Septic; Staph

1996
[Succinylcholine apnea in a patient homozygotic for atypical cholinesterase gene].
    Revista espanola de anestesiologia y reanimacion, 1997, Volume: 44, Issue:10

    Topics: Acetylcholinesterase; Adult; Apnea; Homozygote; Humans; Male; Mutation; Neuromuscular Blocking Agent

1997
[Prolonged curarization with suxamethonium in a four-week old infant].
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:1

    Topics: Apnea; Cholinesterases; Genotype; Humans; Infant, Newborn; Intraoperative Complications; Male; Neuro

1998
Critical hemoglobin desaturation can be delayed by apneic diffusion oxygenation.
    Anesthesiology, 1999, Volume: 90, Issue:1

    Topics: Anesthesia, General; Apnea; Diffusion; Hemoglobins; Humans; Insufflation; Neuromuscular Depolarizing

1999
Suxamethonium and mivacurium sensitivity from pregnancy-induced plasma cholinesterase deficiency.
    Anaesthesia, 1998, Volume: 53, Issue:11

    Topics: Adult; Apnea; Cholinesterases; Female; Humans; Isoquinolines; Mivacurium; Neuromuscular Depolarizing

1998
An explanation for the different inhibitory characteristics of human serum butyrylcholinesterase phenotypes deriving from inhibition of atypical heterozygotes.
    Chemico-biological interactions, 1999, May-14, Volume: 119-120

    Topics: Apnea; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Dibucaine; Genetic Carrier Scre

1999
[Pharmacogenic postoperative apnea. Bambuterol and succinylcholine].
    Archivos de bronconeumologia, 1999, Volume: 35, Issue:8

    Topics: Aged; Aged, 80 and over; Apnea; Bronchodilator Agents; Drug Interactions; Humans; Male; Neuromuscula

1999
A case of pseudocholinesterase deficiency in the neonate.
    American journal of perinatology, 1999, Volume: 16, Issue:7

    Topics: Apnea; Butyrylcholinesterase; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Neuromuscula

1999
Acquired pseudocholinesterase deficiency after high-dose cyclophosphamide.
    Bone marrow transplantation, 1999, Volume: 24, Issue:12

    Topics: Adrenal Gland Neoplasms; Apnea; Butyrylcholinesterase; Child, Preschool; Cyclophosphamide; Dose-Resp

1999
Emergency caesarean section and suxamethonium apnoea.
    Hospital medicine (London, England : 1998), 1998, Volume: 59, Issue:12

    Topics: Adult; Anesthesia, Obstetrical; Apnea; Cesarean Section; Cholinesterases; Contraindications; Drug Hy

1998
Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard.
    Military medicine, 2000, Volume: 165, Issue:8

    Topics: Anesthesia, General; Anesthetics; Animals; Apnea; Chemical Warfare; Disease Models, Animal; Drug Eva

2000
Hemoglobin desaturation after succinylcholine-induced apnea: a study of the recovery of spontaneous ventilation in healthy volunteers.
    Anesthesiology, 2001, Volume: 94, Issue:5

    Topics: Adolescent; Adult; Apnea; Female; Hemoglobins; Humans; Male; Neuromuscular Depolarizing Agents; Oxyg

2001
The intubating dose of succinylcholine.
    Anesthesiology, 2002, Volume: 96, Issue:2

    Topics: Anesthesia; Apnea; Humans; Neuromuscular Depolarizing Agents; Succinylcholine

2002
The safety of rapid sequence induction.
    Anesthesiology, 2002, Volume: 96, Issue:2

    Topics: Anesthesia; Apnea; Hemoglobins; Humans; Neuromuscular Depolarizing Agents; Succinylcholine

2002
Naturally occurring mutation, Asp70his, in human butyrylcholinesterase.
    Annals of clinical biochemistry, 2002, Volume: 39, Issue:Pt 2

    Topics: Amino Acid Substitution; Apnea; Asian People; Aspartic Acid; Black People; Butyrylcholinesterase; Hi

2002
[Plasma cholinesterase variations as a result of prolonged neuromuscular blockade. Review and problems encountered in two cases of prolonged neuromuscular blockade after muscle relaxation with succinylcholine as compared to mivacurium].
    Der Anaesthesist, 2002, Volume: 51, Issue:2

    Topics: Apnea; Cholinesterases; Humans; Isoquinolines; Male; Middle Aged; Mivacurium; Neuromuscular Depolari

2002
Assessment of a diagnostic dip-stick for assaying plasma or serum pseudocholinesterase activity.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Jul-15, Volume: 54, Issue:3

    Topics: Apnea; Blood Chemical Analysis; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Cholin

1978
Scientific Review No. 5. Assay of cholinesterase in clinical chemistry.
    Annals of clinical biochemistry, 1979, Volume: 16, Issue:2

    Topics: Acetylcholinesterase; Animals; Apnea; Buffers; Chemistry, Clinical; Cholinesterase Inhibitors; Choli

1979
[A case of succinylcholine apnea. Identification of genetic variants].
    Annales de l'anesthesiologie francaise, 1979, Volume: 20, Issue:2

    Topics: Apnea; Cholinesterases; Female; Genetic Variation; Humans; Pedigree; Succinylcholine

1979
[A spectrophotometric method for the determination of serum cholinesterase variants with succinyl choline as substrate (author's transl)].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1975, Volume: 13, Issue:4

    Topics: Anesthesia; Animals; Apnea; Choline; Cholinesterase Inhibitors; Cholinesterases; Cytochrome c Group;

1975
Prolonged apnea following trimethaphan and succinylcholine.
    Anesthesiology, 1979, Volume: 50, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Obstetrical; Apnea; Cholinesterases; Female; Humans; Injec

1979
Serum cholinesterase activity in burned patients. II: anaesthesia, suxamethonium and hyperkalaemia.
    Acta anaesthesiologica Scandinavica, 1975, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia; Apnea; Burns; Carbon Dioxide; Child; Cholinesterases; Electroca

1975
Pseudocholinesterase variation.
    Human genetics. Supplement, 1978, Issue:1

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Female; Genetic Carrier Screening; Genetic Variation;

1978
Prolonged apnea of an oral surgery patient after administration of succinylcholine.
    Journal of oral surgery (American Dental Association : 1965), 1979, Volume: 37, Issue:6

    Topics: Adolescent; Anesthesia, Dental; Anesthesia, General; Apnea; Butyrylcholinesterase; Cholinesterase In

1979
[Increase of anesthetic hazards through the use of modern anthelmintics in the horse].
    Berliner und Munchener tierarztliche Wochenschrift, 1979, Volume: 92, Issue:4

    Topics: Anesthesia; Animals; Anthelmintics; Apnea; Drug Interactions; Horse Diseases; Horses; Succinylcholin

1979
Succinylcholine-induced apnea.
    Anesthesiology, 1979, Volume: 50, Issue:3

    Topics: Apnea; Butyrylcholinesterase; Humans; Succinylcholine

1979
Abnormal enzyme phenotype (E1a E1f): normal response to succinylcholine.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:2

    Topics: Adolescent; Apnea; Cholinesterases; Heterozygote; Humans; Male; Phenotype; Succinylcholine; Temperat

1979
Succinylcholine sensitivity in a Nova Scotia family.
    Canadian Anaesthetists' Society journal, 1978, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Anesthesia; Apnea; Cholinesterases; Female; Genotype; Homozygote; Humans; Male; P

1978
Hazards of succinylcholine administration during electrotherapy.
    Archives of general psychiatry, 1978, Volume: 35, Issue:9

    Topics: Aged; Anti-Bacterial Agents; Apnea; Arrhythmias, Cardiac; Cholinesterase Inhibitors; Cholinesterases

1978
[Current evalution of the test for detecting atypical cholinesterase].
    Revista espanola de anestesiologia y reanimacion, 1978, Volume: 25, Issue:3

    Topics: Adult; Apnea; Child; Cholinesterases; Female; Humans; Male; Middle Aged; Pedigree; Succinylcholine

1978
Prolonged apnoea after suxamethonium: an analysis of the first 225 cases reported to the Danish Cholinesterase Research Unit.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Apnea; Child; Child, Preschool; Cholinesterases; Female; Genotype; Humans;

1978
Succinylcholine-prolonged apnea associated with clindamycin and abnormal liver function tests.
    Diseases of the nervous system, 1977, Volume: 38, Issue:6

    Topics: Adolescent; Apnea; Clindamycin; Female; Humans; Liver Function Tests; Schizophrenia; Succinylcholine

1977
The use of serum cholinesterase in succinylcholine apnoea.
    Canadian Anaesthetists' Society journal, 1977, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Apnea; Child; Cholinesterases; Female; Humans; Male; Middle Aged; Phenotype; Succ

1977
Prolonged apnoea due to suxamethonium in Chinese.
    Anaesthesia and intensive care, 1977, Volume: 5, Issue:3

    Topics: Adult; Anesthesia, Intravenous; Apnea; Butyrylcholinesterase; China; Humans; Male; Succinylcholine

1977
A Danish cholinesterase research unit.
    Acta anaesthesiologica Scandinavica, 1977, Volume: 21, Issue:5

    Topics: Apnea; Cholinesterases; Denmark; Dibucaine; Female; Genetic Variation; Genotype; Humans; Male; Pedig

1977
Suxamethonium apnoea terminated with commercial serumcholinesterase.
    Acta anaesthesiologica Scandinavica, 1976, Volume: 20, Issue:3

    Topics: Adjuvants, Anesthesia; Apnea; Cholinesterases; Humans; Injections, Intravenous; Male; Middle Aged; S

1976
[A Danish cholinesterase card index].
    Ugeskrift for laeger, 1976, Sep-20, Volume: 138, Issue:39

    Topics: Apnea; Cholinesterases; Denmark; Genotype; Humans; Registries; Succinylcholine

1976
[Succinyldicholin sensitivity resulting from genetically determined serumcholinesterase variants].
    Praktische Anasthesie, Wiederbelebung und Intensivtherapie, 1976, Volume: 11, Issue:5

    Topics: Alleles; Apnea; Cholinesterases; Drug Hypersensitivity; Female; Genotype; Homozygote; Humans; Male;

1976
Hypersensitivity to suxamethonium in a Suffolk family.
    British journal of anaesthesia, 1976, Volume: 48, Issue:7

    Topics: Adult; Apnea; Cholinesterases; Drug Hypersensitivity; Female; Homozygote; Humans; Pedigree; Succinyl

1976
Survey of local anesthetic toxicity in the families of patients with atypical plasma cholinesterase.
    Journal of oral surgery (American Dental Association : 1965), 1975, Volume: 33, Issue:11

    Topics: Anesthetics, Local; Apnea; Benzoylcholine; Cholinesterases; Dibucaine; Heterozygote; Homozygote; Hum

1975
Succinylcholine-induced apnoea.
    Dental journal, 1976, Volume: 42, Issue:7

    Topics: Anesthesia, Dental; Apnea; Child, Preschool; Humans; Male; Succinylcholine

1976
Letter: criticism of a selected method: propionylthiocholinesterase.
    Clinical chemistry, 1975, Volume: 21, Issue:7

    Topics: Apnea; Choline; Cholinesterases; Drug Hypersensitivity; Heterozygote; Humans; Phenotype; Propionates

1975
[Case of protracted apnea due to succinylcholine (duration: 7 hours)].
    Minerva anestesiologica, 1975, Volume: 41, Issue:5

    Topics: Aged; Apnea; Female; Humans; Succinylcholine; Time Factors

1975
Response of the newborn to succinlycholine injection in homozygotic atypical mothers.
    Anesthesiology, 1975, Volume: 43, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Apnea; Cesarean Section; Cholinesterases; D

1975
[Familial examinations for the presence of atypical cholinesterase].
    Nederlands tijdschrift voor geneeskunde, 1975, Oct-04, Volume: 119, Issue:40

    Topics: Adolescent; Anesthesia, General; Apnea; Appendectomy; Child, Preschool; Cholinesterase Inhibitors; C

1975
Incidence of suxamethonium apnoea in patients undergoing E.C.T.
    British journal of anaesthesia, 1975, Volume: 47, Issue:11

    Topics: Apnea; Cholinesterases; Humans; Phenotype; Succinylcholine

1975
Suxamethonium sensitivity and segregation of human serum cholinesterase variants at locus, Ch1, among twelve British families.
    Human heredity, 1975, Volume: 25, Issue:6

    Topics: Apnea; Cholinesterases; Drug Hypersensitivity; Female; Genetic Variation; Genotype; Humans; Male; Su

1975
Central neural stimulation of respiration in unanesthetized decerebrate cats.
    Journal of applied physiology, 1976, Volume: 40, Issue:1

    Topics: Animals; Apnea; Brain; Carbon Dioxide; Carotid Sinus; Cats; Decerebrate State; Gallamine Triethiodid

1976
A note on suxamethonium sensitivity and serum cholinesterase variants.
    Human genetics, 1976, Apr-15, Volume: 32, Issue:1

    Topics: Apnea; Cholinesterases; Drug Hypersensitivity; Genetic Variation; Humans; Succinylcholine

1976
Plasma cholinesterase variants - an unexpectedly high incidence of the silent allele.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1976, Feb-28, Volume: 50, Issue:9

    Topics: Adolescent; Adult; Alleles; Apnea; Butyrylcholinesterase; Child; Child, Preschool; Cholinesterases;

1976
Reversal of prolonged suxamethonium apnoea.
    Anaesthesia, 1992, Volume: 47, Issue:7

    Topics: Apnea; Blood Transfusion; Cholinesterases; Humans; Infant; Plasma; Succinylcholine

1992
Succinylcholine-induced prolonged apnea in a 3-week-old newborn: treatment with human plasma cholinesterase.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:1

    Topics: Apnea; Cholinesterases; Genotype; Halothane; Humans; Infant, Newborn; Male; Succinylcholine

1992
[Succinylcholine-induced prolonged apnea and hyperthermia in a patient with organophosphate insecticide poisoning].
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1991, Volume: 29, Issue:2

    Topics: Adult; Apnea; Fever; Humans; Insecticides; Male; Organophosphorus Compounds; Succinylcholine

1991
Reversal of prolonged suxamethonium apnoea with fresh frozen plasma in a 6-week-old infant.
    Anaesthesia, 1991, Volume: 46, Issue:12

    Topics: Apnea; Cholinesterases; Homozygote; Humans; Infant; Male; Pedigree; Plasma; Succinylcholine; Time Fa

1991
Suxamethonium in bunged cannulae.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:3

    Topics: Apnea; Catheterization, Peripheral; Child; Equipment Design; Equipment Safety; Humans; Injections, I

1991
Scoline apnoea: a relatively common problem.
    SAAD digest, 1990, Volume: 7, Issue:10

    Topics: Adult; Anesthesia, Dental; Anesthesia, General; Apnea; Dental Care for Disabled; Humans; Male; Succi

1990
[Prolonged action of relaxants of the succinyldicholine group in carriers of atypical forms of serum cholinesterase].
    Vestnik khirurgii imeni I. I. Grekova, 1990, Volume: 145, Issue:8

    Topics: Adult; Anesthesia, Endotracheal; Apnea; Appendicitis; Cholinesterases; Delayed-Action Preparations;

1990
Pre-eclampsia, dural tap and suxamethonium apnoea.
    British journal of hospital medicine, 1990, Volume: 43, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Intravenous; Anesthesia, Obstetrical; Apnea; Female; Humans

1990
Is there a use for stabilised human serum in the treatment of Scoline apnoea? A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, Mar-17, Volume: 77, Issue:6

    Topics: Adult; Apnea; Blood Transfusion; Cholinesterases; Female; Humans; Succinylcholine

1990
Prolonged succinylcholine-induced paralysis in organophosphate insecticide poisoning.
    Annals of emergency medicine, 1987, Volume: 16, Issue:2

    Topics: Apnea; Child, Preschool; Chlorpyrifos; Cholinesterases; Female; Humans; Paralysis; Pralidoxime Compo

1987
[Prolonged apnea after suxamethonium related to congenital abnormality of plasma pseudocholinesterase].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:1

    Topics: Anesthesia, General; Apnea; Butyrylcholinesterase; Child; Cholinesterases; Humans; Male; Pedigree; P

1989
Automated determination of cholinesterase activity in plasma and erythrocytes by flow-injection analysis, and application to identify subjects sensitive to succinylcholine.
    Clinical chemistry, 1989, Volume: 35, Issue:1

    Topics: Adult; Aging; Anesthesia; Apnea; Autoanalysis; Cholinesterases; Erythrocytes; Female; Humans; Male;

1989
Prolonged suxamethonium-induced neuromuscular block associated with organophosphate poisoning.
    British journal of anaesthesia, 1989, Volume: 62, Issue:2

    Topics: Apnea; Child, Preschool; Humans; Intraoperative Complications; Larynx; Male; Organophosphate Poisoni

1989
Effect of plasma cholinesterase activity on the duration of action of succinylcholine in patients with genotypically normal enzyme.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:11

    Topics: Adult; Apnea; Cholinesterases; Genotype; Humans; Liver Transplantation; Neuromuscular Junction; Succ

1988
An alternative approach to the prevention of succinyldicholine-induced apnoea.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1988, Volume: 26, Issue:2

    Topics: Apnea; Butyrylcholinesterase; Cholinesterases; Humans; Methods; Succinylcholine

1988
Prolonged suxamethonium-induced neuromuscular blockade associated with organophosphate poisoning.
    British journal of anaesthesia, 1988, Volume: 61, Issue:2

    Topics: Adult; Apnea; Cholinesterases; Humans; Malathion; Male; Succinylcholine; Time Factors

1988
[Phenotype of plasma cholinesterase in prolonged apnea and sensitivity to succinylcholine].
    Cahiers d'anesthesiologie, 1987, Volume: 35, Issue:8

    Topics: Anesthesia, General; Apnea; Cholinesterase Inhibitors; Dibucaine; Family; Female; Humans; Phenotype;

1987
Suxamethonium apnoea in a 4-month-old twin.
    Anaesthesia, 1987, Volume: 42, Issue:8

    Topics: Apnea; Cholinesterases; Diseases in Twins; Genotype; Humans; Infant; Intraoperative Complications; M

1987
Is succinyldicholine the substrate of choice for the measurement of cholinesterase activity?
    Clinical chemistry, 1986, Volume: 32, Issue:8

    Topics: Adult; Apnea; Cholinesterases; Heterozygote; Humans; Male; Middle Aged; Succinylcholine; Thiocholine

1986
Pesticide poisoning, succinylcholine-induced apnea, and pseudocholinesterase.
    Mayo Clinic proceedings, 1986, Volume: 61, Issue:9

    Topics: Apnea; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Humans; Pestici

1986
Prolonged neuromuscular blockade following suxamethonium in a patient with a normal genotype.
    Anaesthesia, 1986, Volume: 41, Issue:8

    Topics: Apnea; Child; Cholinesterases; Female; Genotype; Humans; Postoperative Complications; Succinylcholin

1986
Combined electroconvulsive and drug therapy.
    Comprehensive therapy, 1985, Volume: 11, Issue:7

    Topics: Anesthesia; Apnea; Atropine; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Elect

1985
Suxamethonium apnoea.
    Lancet (London, England), 1973, Feb-03, Volume: 1, Issue:7797

    Topics: Anesthesia; Apnea; Cholinesterase Inhibitors; Cholinesterases; Drug Synergism; Humans; Liver; Metabo

1973
Blood-gas tensions during apnoea in hyperbaric oxygen.
    Lancet (London, England), 1966, Dec-24, Volume: 2, Issue:7478

    Topics: Acidosis; Acidosis, Respiratory; Animals; Apnea; Asphyxia Neonatorum; Blood Gas Analysis; Humans; Hy

1966
[A case of prolonged apnea in Huntington's chorea].
    Acta anaesthesiologica, 1968, Volume: 19

    Topics: Anesthesia; Apnea; Female; Humans; Huntington Disease; Middle Aged; Succinylcholine; Surgical Proced

1968
Abnormal responses to muscle relaxants in a patient with Von Recklinghausen's disease (multiple neurofibromatosis).
    British journal of anaesthesia, 1970, Volume: 42, Issue:8

    Topics: Adult; Androstanes; Apnea; Humans; Male; Neurofibromatosis 1; Neuromuscular Nondepolarizing Agents;

1970
Plasma cholinesterase deficiency. A possible complication during anesthesia.
    Obstetrics and gynecology, 1972, Volume: 39, Issue:4

    Topics: Adolescent; Anesthesia, General; Apnea; Cholinesterases; Endoscopy; Female; Genotype; Humans; Intuba

1972
[Cholinesterase and Huntington's chorea].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1971, Volume: 7, Issue:1

    Topics: Anesthesia; Apnea; Cholinesterases; Female; Humans; Huntington Disease; Middle Aged; Succinylcholine

1971
Suxamethonium--a review. II. Neuromuscular blocking properties.
    Anaesthesia and intensive care, 1973, Volume: 1, Issue:3

    Topics: Acid-Base Equilibrium; Action Potentials; Adult; Anesthetics; Apnea; Decamethonium Compounds; Dose-R

1973
Effects of intravenous and intra-arterial procaine and lidocaine on neuromuscular transmission in man.
    Acta anaesthesiologica Scandinavica. Supplementum, 1969, Volume: 36

    Topics: Apnea; Drug Synergism; Humans; Injections, Intra-Arterial; Injections, Intravenous; Lidocaine; Muscl

1969
Succinylcholine--prolonged apnoea and some dangers.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Sep-05, Volume: 44, Issue:35

    Topics: Acetylcholine; Acetylcholinesterase; Adult; Alleles; Apnea; Autonomic Nerve Block; Biological Transp

1970
Succinylcholine-hexafluorenium combination for muscular relaxation: a reappraisal.
    Southern medical journal, 1968, Volume: 61, Issue:8

    Topics: Adolescent; Adult; Aged; Apnea; Blood Pressure; Child; Drug Synergism; Female; Ganglionic Blockers;

1968
[Decreasing of suxamethonium induced apnea with Akrinor].
    Der Anaesthesist, 1969, Volume: 18, Issue:9

    Topics: Adjuvants, Anesthesia; Apnea; Central Nervous System Stimulants; Humans; Succinylcholine; Time Facto

1969
Letter: Death after E.C.T.
    British medical journal, 1974, Sep-07, Volume: 3, Issue:5931

    Topics: Amitriptyline; Apnea; Cholinesterases; Electroconvulsive Therapy; Humans; Succinylcholine

1974
Aetiology of prolonged apnoea after suxamethonium.
    British journal of anaesthesia, 1974, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Aged; Apnea; Catalysis; Child; Child, Preschool; Cholinesterases; Dibucaine; Drug

1974
[Plasma cholinesterase (CHE, pseudocholinesterase), its importance in liver diseases and prolonged succinyldicholine-induced apnea].
    Hippokrates, 1974, Volume: 45, Issue:4

    Topics: Apnea; Cholinesterases; Humans; Immunoglobulins; Liver; Liver Diseases; Succinylcholine

1974
Abnormal response to a muscle relaxant. Report of three cases.
    The Journal of the American Association of Nurse Anesthetists, 1973, Volume: 41, Issue:5

    Topics: Apnea; Cholinesterases; Metabolism, Inborn Errors; Succinylcholine

1973
A case study: Anectine and apnea.
    AANA journal, 1974, Volume: 42, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Apnea; Child; Child, Preschool; Cholinesterases; Drug Hypersensitivit

1974
Cyclophosphamide, cholinesterase and anaesthesia.
    Australian and New Zealand journal of medicine, 1972, Volume: 2, Issue:3

    Topics: Adult; Anesthesia, General; Apnea; Blood Transfusion; Cholinesterases; Cyclophosphamide; Female; Hum

1972
Sensitivity to succinylcholine.
    Journal of oral surgery (American Dental Association : 1965), 1973, Volume: 31, Issue:9

    Topics: Apnea; Cholinesterases; Humans; Succinylcholine

1973
Relationship between suxamethonium apnoea, serum cholinesterase activity and inhibitor numbers.
    British journal of anaesthesia, 1974, Volume: 46, Issue:12

    Topics: Apnea; Cholinesterase Inhibitors; Cholinesterases; Heterozygote; Homozygote; Humans; Phenotype; Succ

1974
Effects of bitemporal electrical stimulation on the duration of suxamethonium apnoea in man.
    British journal of anaesthesia, 1974, Volume: 46, Issue:12

    Topics: Adult; Anesthesia, Intravenous; Apnea; Atropine; Electroconvulsive Therapy; Female; Humans; Male; Ox

1974
A rare constellation of serum cholinesterase genetic variants.
    Enzyme, 1972, Volume: 13, Issue:5-6

    Topics: Adolescent; Adult; Apnea; Cholinesterases; Erythrocytes; Female; Genetic Variation; Heterozygote; HL

1972
Apnea and atypical pseudocholinesterase.
    Southern medical journal, 1973, Volume: 66, Issue:5

    Topics: Adult; Apnea; Cholinesterases; Female; Humans; Male; Metabolism, Inborn Errors; Succinylcholine

1973
Scoline apnoea.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Jun-02, Volume: 47, Issue:21

    Topics: Anesthesia, General; Apnea; Cholinesterases; Humans; Male; Metabolism, Inborn Errors; Middle Aged; S

1973
Scoline apnoea.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Aug-11, Volume: 47, Issue:31

    Topics: Apnea; Humans; Methods; Succinylcholine

1973
[The application of serum cholinesterase in prolonged apnoea following suxamethonium].
    Der Anaesthesist, 1973, Volume: 22, Issue:5

    Topics: Anesthesia, Intravenous; Apnea; Cholinesterases; Humans; Male; Middle Aged; Succinylcholine; Thiopen

1973
Apnea in an atypical-fluoride resistant (E1aE1f) heterozygote for serum cholinesterase.
    Anesthesiology, 1973, Volume: 39, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia, Endotracheal; Apnea; Child, Preschool; Cholinesterases; Drug Resi

1973
Succinylcholine and pseudocholinesterase.
    JAMA, 1973, Sep-17, Volume: 225, Issue:12

    Topics: Apnea; Cholinesterases; Humans; Succinylcholine

1973
Prolonged apnea in an infant following the use of succinylcholine.
    Anesthesiology, 1973, Volume: 39, Issue:5

    Topics: Anesthesia, Inhalation; Apnea; Cholinesterases; Genotype; Humans; Infant; Male; Pedigree; Pyloric St

1973
Apneic anesthesia for microlaryngeal surgery.
    The Laryngoscope, 1973, Volume: 83, Issue:8

    Topics: Anesthesia, Intravenous; Apnea; Carbon Dioxide; Humans; Hydrogen-Ion Concentration; Laryngoscopy; La

1973
[Long-term succinylcholine apnea. Genetic aspects].
    Revista espanola de anestesiologia y reanimacion, 1974, Volume: 21, Issue:1

    Topics: Apnea; Humans; Pedigree; Succinylcholine; Time Factors

1974
Dangers of succinylcholine in anesthesia.
    The Laryngoscope, 1974, Volume: 84, Issue:6

    Topics: Anesthesia; Apnea; Cholinesterases; Clinical Enzyme Tests; Dose-Response Relationship, Drug; Humans;

1974
Atypical plasma cholinesterase, succinylcholine, and prolonged apnea.
    Southern medical journal, 1974, Volume: 67, Issue:9

    Topics: Aged; Anesthesia; Apnea; Cholinesterases; Dibucaine; Female; Humans; Succinylcholine; Time Factors

1974
Half-life of human serum cholinesterase following blood transfusion.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:2

    Topics: Adult; Albumins; Apnea; Blood Proteins; Blood Transfusion; Cholinesterases; Female; Half-Life; Human

1974
Carbon dioxide elimination during bronchoscopy. A comparison of two alternative general anaesthetic techniques.
    British journal of anaesthesia, 1968, Volume: 40, Issue:7

    Topics: Analysis of Variance; Anesthesia, General; Apnea; Arrhythmias, Cardiac; Blood Specimen Collection; B

1968
Qualitative defects of pseudocholinesterase activity.
    Anaesthesia, 1967, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Apnea; Child; Cholinesterases; Clinical Enzyme Tests; Cyclophosphamide; Dib

1967
Genetics of esterases in man.
    Annals of the New York Academy of Sciences, 1968, Jul-31, Volume: 151, Issue:2

    Topics: Acetylcholinesterase; Adult; Apnea; Asian People; Biotransformation; Black People; Blood Protein Ele

1968
Therapy of prolonged apnea after suxamthonium with purified pseudocholinesterase. New data on kinetics of the hydrolysis of succinyldicholine and succinylmonocholine and further data on N-acetyltransferase-polymorphism.
    Annals of the New York Academy of Sciences, 1968, Jul-31, Volume: 151, Issue:2

    Topics: Alleles; Ammonium Chloride; Aniline Compounds; Animals; Apnea; Carbon Isotopes; Cholinesterases; Coe

1968
Aspects of suxamethonium hydrolysis in man and animals.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:2

    Topics: Acetylcholine; Acetylcholinesterase; Alleles; Animals; Apnea; Cats; Cholinesterase Inhibitors; Choli

1970
Suxamethonium sensitivity.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Apnea; Carbon Isotopes; Cholinesterase Inhibitors; Cholinesterases; Drug Hypersensitivity; Drug Stab

1971
Serum cholinesterase, pregnancy and suxamethonium.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Anesthesia, Obstetrical; Apnea; Cesarean Section; Cholinesterases; Female; Humans; Infant, Newborn;

1972
Suxamethonium apnoea in a child.
    Nursing times, 1972, May-04, Volume: 68, Issue:18

    Topics: Apnea; Child, Preschool; Female; Humans; Succinylcholine

1972
Detection of patients with low serum cholinesterase activity: inadequacy of "Acholest" method.
    Clinical chemistry, 1972, Volume: 18, Issue:6

    Topics: Apnea; Blood Protein Disorders; Choline; Cholinesterases; Heterozygote; Homozygote; Humans; Methods;

1972
Effect of propranolol hydrochloride on the neuromuscular blocking action of d-tubocurarine and succinylcholine in man.
    The Indian journal of medical research, 1972, Volume: 60, Issue:2

    Topics: Apnea; Drug Antagonism; Humans; Neuromuscular Junction; Propranolol; Succinylcholine; Tubocurarine

1972
Succinylcholine dosage based on lean body mass.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Body Weight; Female; Halothane; Humans; Intubat

1972
An original approach to the diagnosis of scoline-induced apnoea.
    Journal of clinical pathology, 1972, Volume: 25, Issue:5

    Topics: Apnea; Cholinesterases; Dibucaine; Heterozygote; Homozygote; Humans; Hydrogen-Ion Concentration; Hyd

1972
[Pseudocholinesterase].
    Duodecim; laaketieteellinen aikakauskirja, 1972, Volume: 88, Issue:5

    Topics: Anesthesia; Apnea; Cholinesterase Inhibitors; Cholinesterases; Enzyme Activation; Genotype; Humans;

1972
A rapid measurement of functional residual capacity in the paralyzed dog.
    Journal of applied physiology, 1972, Volume: 33, Issue:4

    Topics: Animals; Apnea; Dogs; Lung; Methods; Paresis; Plethysmography, Whole Body; Pulmonary Ventilation; Re

1972
Deaths with dental anaesthetics.
    Anaesthesia, 1971, Volume: 26, Issue:3

    Topics: Anesthesia, Dental; Apnea; Brain Diseases; Child; Female; Humans; Hypotension; Posture; Succinylchol

1971
[Data on serum cholinesterase activity in cases of prolonged apnea due to succinylcholine].
    Minerva anestesiologica, 1971, Volume: 37, Issue:5

    Topics: Adult; Anesthesia; Apnea; Appendectomy; Child, Preschool; Cholecystectomy; Cholinesterases; Female;

1971
Organophosphate-induced complications during anesthetic management in the horse.
    Journal of the American Veterinary Medical Association, 1971, Dec-01, Volume: 159, Issue:11

    Topics: Anesthesia; Animals; Apnea; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Carbon Disulfide;

1971
[Cholinesterase and prolonged apnea due to succinylcholine].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1971, Volume: 7, Issue:1

    Topics: Adult; Anesthesia; Apnea; Cholinesterases; Female; Humans; Hydrolysis; Hypercapnia; Male; Middle Age

1971
Malignant hyperthermia during anaesthesia. A neurophysiological and neuropathological follow-up study of a patient and his family.
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:4

    Topics: Action Potentials; Adolescent; Adult; Anesthesia, General; Apnea; Biopsy; Central Nervous System; Ch

1971
Suxamethonium sensitivity.
    The New Zealand medical journal, 1967, Volume: 66, Issue:415

    Topics: Anesthesia, General; Apnea; Blood Transfusion; Child; Cholinesterases; Dibucaine; Drug Hypersensitiv

1967
Possible interaction between muscle relaxants and the kallikrein-trypsin inactivator "Trasylol". Report of three cases.
    British journal of anaesthesia, 1966, Volume: 38, Issue:10

    Topics: Adult; Anesthesia, General; Apnea; Aprotinin; Drug Synergism; Female; Gastrointestinal Hemorrhage; H

1966
The influence of the kallikrein-trypsin inactivator Trasylol on the serum cholinesterase.
    British journal of anaesthesia, 1968, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Aged; Apnea; Aprotinin; Cholinesterase Inhibitors; Cholinesterases; Female; Human

1968
[Prolonged succinyl apnea as an indication of alkylphosphate poisoning].
    Deutsche medizinische Wochenschrift (1946), 1968, Jul-19, Volume: 93, Issue:29

    Topics: Adult; Anesthesia, General; Apnea; Cerebral Ventriculography; Cholinesterase Inhibitors; Humans; Ins

1968
Influence of aprotinin (Trasylol) on the action of suxamethonium.
    British journal of anaesthesia, 1970, Volume: 42, Issue:11

    Topics: Apnea; Aprotinin; Cholinesterase Inhibitors; Cholinesterases; Humans; Injections, Intravenous; Respi

1970
Variation in cardiac output with acid-base changes in the anesthetized dog.
    Journal of applied physiology, 1965, Volume: 20, Issue:5

    Topics: Acidosis; Acidosis, Respiratory; Animals; Apnea; Blood Circulation; Blood Gas Analysis; Carbon Dioxi

1965
[Succinycholine apnea].
    Revista espanola de anestesiologia y reanimacion, 1969, Volume: 16, Issue:3

    Topics: Apnea; Female; Humans; Middle Aged; Succinylcholine

1969
Prolonged suxamethonium-induced apnoea as a sign of organophosphate poisoning.
    German medical monthly, 1969, Volume: 14, Issue:1

    Topics: Adult; Apnea; Humans; Male; Parathion; Phosphates; Poisoning; Succinylcholine; Suicide

1969
A new test for cholinesterase (ChE) prior to electro shock therapy.
    Diseases of the nervous system, 1969, Volume: 30, Issue:10

    Topics: Apnea; Cholinesterases; Electroconvulsive Therapy; Humans; Methods; Succinylcholine

1969
[The activity of respiratory neurons in the absence of respiratory movements].
    Biulleten' eksperimental'noi biologii i meditsiny, 1969, Volume: 68, Issue:12

    Topics: Animals; Apnea; Cats; Electrophysiology; Lung; Medulla Oblongata; Neurons, Afferent; Respiration; Re

1969
A simple test for abnormal pseudocholinesterase.
    Anesthesiology, 1970, Volume: 32, Issue:3

    Topics: Anesthesia; Apnea; Cholinesterases; Female; Humans; Middle Aged; Succinylcholine

1970
[Apnea due to succinyldicholine: study of a French-Canadian population].
    Canadian Anaesthetists' Society journal, 1970, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Apnea; Canada; Child; Choline; Cholinesterases; Female; Humans; Male; Middl

1970
The neuromuscular blocking properties of the antimalarial agent, bis((chloro-7"-quinolyl-4")amino-2'-propyl)-1,4-piperazine.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 172, Issue:1

    Topics: Acetylcholine; Animals; Antimalarials; Apnea; Calcium; Chloroquine; Diaphragm; Electric Stimulation;

1970
The effects of anesthesia and 100 per cent oxygen on the functional residual capacity of the lungs.
    Anesthesiology, 1970, Volume: 32, Issue:6

    Topics: Adult; Apnea; Female; Halothane; Helium; Humans; Lung; Male; Middle Aged; Oxygen; Respiration; Rest;

1970
A family study of atypical plasma cholinesterase activity.
    Southern medical journal, 1970, Volume: 63, Issue:7

    Topics: Adult; Apnea; Child; Cholinesterases; Clinical Enzyme Tests; Diagnosis, Differential; Dibucaine; Fem

1970
An appraisal of tacrine-extended suxamethonium.
    British journal of anaesthesia, 1970, Volume: 42, Issue:2

    Topics: Acridines; Adult; Aged; Anesthesia, General; Apnea; Appendectomy; Cholinesterases; Drug Synergism; H

1970
The temperature activity relationships of serum cholinesterases.
    Journal of clinical pathology, 1970, Volume: 23, Issue:8

    Topics: Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Fluorides; Humans; Phenotype; Succinyl

1970
Initial experiences with the Cholinesterase Research Unit.
    British journal of anaesthesia, 1970, Volume: 42, Issue:11

    Topics: Apnea; Child; Cholinesterases; Dibucaine; Female; Fluorides; Genotype; Heterozygote; Humans; Male; M

1970
[Depolarizing relaxants (succinylcholine) in children].
    Revista espanola de anestesiologia y reanimacion, 1970, Volume: 17, Issue:2

    Topics: Apnea; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Injections, Intramuscular; Injectio

1970
Genetics--the anaesthetist at risk.
    South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 1970, Volume: 8, Issue:4

    Topics: Apnea; Barbiturates; Dibucaine; Female; Fever; Humans; Hydrocarbons, Halogenated; Male; Nitrous Oxid

1970
The effects of other drugs on the stimulation of laryngospasm in the cat: atropine; thiopentone, suxamethonium; local analgesics.
    British journal of anaesthesia, 1971, Volume: 43, Issue:2

    Topics: Anesthetics, Local; Animals; Apnea; Atropine; Cats; Laryngismus; Larynx; Lidocaine; Respiration; Suc

1971
Plasma cholinesterase activity in newborns and infants.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:3

    Topics: Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Female; Halothane; Heart Block; Humans

1971
[The enzymatic degradation of succinic acid dicholine ester in the human lung].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1967, Volume: 348, Issue:1

    Topics: Acetylcholinesterase; Adolescent; Adult; Age Factors; Aged; Apnea; Blood Proteins; Cholinesterases;

1967
[Prolonged apnea induced by succinylcholine].
    Rassegna internazionale di clinica e terapia, 1967, May-31, Volume: 47, Issue:10

    Topics: Anesthesia; Apnea; Humans; Succinylcholine

1967
[Clinical study of prolonged apnea due to succinylcholine during gynecologic interventions].
    Rivista di ostetricia e ginecologia, 1967, Volume: 22, Issue:7

    Topics: Anesthesia, Endotracheal; Apnea; Female; Humans; Leiomyoma; Middle Aged; Succinylcholine; Uterine Ce

1967
[Respiratory insufficiency presumably due to K deficiency after succinylcholine administration--effect of potassium asparaginate].
    Masui. The Japanese journal of anesthesiology, 1967, Volume: 16, Issue:8

    Topics: Anesthesia, Intravenous; Apnea; Asparagine; Female; Humans; Male; Middle Aged; Potassium; Potassium

1967
[Research on serum cholinesterase activity in subjects with prolonged apnea caused by succinylcholine].
    Acta anaesthesiologica, 1967, Volume: 18

    Topics: Adult; Aged; Apnea; Cholinesterases; Female; Humans; Male; Middle Aged; Succinylcholine

1967
Atypical cholinesterase gene E1a: rarity in Negroes and most Orientals.
    Science (New York, N.Y.), 1968, Jan-12, Volume: 159, Issue:3811

    Topics: Alleles; Apnea; Asian People; Black or African American; Cholinesterases; Gene Frequency; Genes, Dom

1968
Punishment of alcohol consumption by apneic paralysis.
    Behaviour research and therapy, 1968, Volume: 6, Issue:1

    Topics: Adult; Alcoholic Beverages; Alcoholism; Apnea; Avoidance Learning; Behavior Therapy; Extinction, Psy

1968
Dynamics of oxygen stores changes following an alteration in ventilation.
    Journal of applied physiology, 1968, Volume: 24, Issue:6

    Topics: Animals; Apnea; Arteries; Asphyxia; Carbon Dioxide; Cardiac Output; Dogs; Models, Biological; Muscle

1968
Suxamethonium apnoea.
    British journal of anaesthesia, 1968, Volume: 40, Issue:5

    Topics: Apnea; Blood Specimen Collection; Cholinesterases; Humans; Succinylcholine

1968
Atypical pseudocholinesterase activity: a review and presentation of two cases.
    Canadian Anaesthetists' Society journal, 1968, Volume: 15, Issue:2

    Topics: Aged; Apnea; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Female; Genetics, Medical; Human

1968
An additional pseudocholinesterase phenotype occurring in suxamethonium apnoea.
    British journal of anaesthesia, 1968, Volume: 40, Issue:8

    Topics: Apnea; Chlorides; Cholinesterases; Clinical Enzyme Tests; Dibucaine; Fluorides; Humans; Middle Aged;

1968
Suxamethonium and intraocular pressure.
    Anaesthesia, 1968, Volume: 23, Issue:3

    Topics: Adult; Age Factors; Anesthesia, Intravenous; Apnea; Child; Child, Preschool; Humans; Infant; Intraoc

1968
Glaucoma associated with suxamethonium apnoea.
    Anaesthesia, 1968, Volume: 23, Issue:3

    Topics: Anesthesia, General; Apnea; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Succinylcholi

1968
[Atypical pseudochlolinesterase and prolonged apnea induced by succinyldicholine: report of 2 cases].
    L'union medicale du Canada, 1968, Volume: 97, Issue:8

    Topics: Adolescent; Apnea; Child; Cholinesterases; Drug Hypersensitivity; Female; Humans; Male; Succinylchol

1968
The drug modification of ECT. II. Succinylcholine dosage.
    Archives of general psychiatry, 1968, Volume: 19, Issue:5

    Topics: Adult; Apnea; Arrhythmias, Cardiac; Atropine; Body Weight; Electroconvulsive Therapy; Electrokymogra

1968
Abnormal reaction to procaine and succinylcholine in a patient with inherited atypical plasma cholinesterase: case report.
    Canadian Anaesthetists' Society journal, 1968, Volume: 15, Issue:5

    Topics: Abdomen; Adjuvants, Anesthesia; Adult; Anesthesia, Local; Apnea; Cholinesterases; Drug Hypersensitiv

1968
Suxamethonium apnoea.
    British medical journal, 1968, Oct-26, Volume: 4, Issue:5625

    Topics: Apnea; Cholinesterases; Humans; Succinylcholine

1968
[Prolonged apnea caused by succinylcholine in obstetrical operations].
    Rassegna internazionale di clinica e terapia, 1968, Jul-31, Volume: 48, Issue:14

    Topics: Adult; Anesthesia, Obstetrical; Apnea; Female; Humans; Pregnancy; Succinylcholine

1968
Sexamethonium and serum cholinesterase. Comparative studies in vitro and in vivo on the catabolism of suxamethonium.
    British journal of anaesthesia, 1968, Volume: 40, Issue:11

    Topics: Apnea; Blood Protein Electrophoresis; Cholinesterase Inhibitors; Cholinesterases; Female; Humans; Mi

1968
[Treatment of the genetically determined hypersensitivity to succinylcholine].
    Der Anaesthesist, 1968, Volume: 17, Issue:10

    Topics: Apnea; Cholinesterases; Drug Hypersensitivity; Humans; Succinylcholine

1968
[Shortening of suxamethonium-induced apnea by Akrinor].
    Der Anaesthesist, 1968, Volume: 17, Issue:11

    Topics: Adolescent; Adult; Anesthesia, Endotracheal; Apnea; Appendectomy; Blood Pressure; Female; Humans; In

1968
[Prolonged apnea following to administration of succinylcholine].
    Minerva anestesiologica, 1968, Volume: 34, Issue:7

    Topics: Adult; Apnea; Cholinesterases; Head and Neck Neoplasms; Humans; Lipoma; Male; Postoperative Complica

1968
[On a case of prolonged apnea after administration of succinylcholine in a patient with fibrocystic disease of the pancreas or mucoviscidosis].
    Acta anaesthesiologica, 1968

    Topics: Adolescent; Anesthesia; Apnea; Appendectomy; Appendicitis; Child; Cystic Fibrosis; Female; Humans; M

1968
Serum cholinesterase deficiency in renal failure.
    Transactions - American Society for Artificial Internal Organs, 1969, Volume: 15

    Topics: Acute Kidney Injury; Anesthesia, General; Apnea; Cholinesterases; Deficiency Diseases; Humans; Kidne

1969
Low serum pseudocholinesterase levels complicating treatment with phenelzine.
    British medical journal, 1969, Aug-30, Volume: 3, Issue:5669

    Topics: Adult; Apnea; Cholinesterases; Electroconvulsive Therapy; Female; Humans; Middle Aged; Phenelzine; S

1969
[Studies on enzymes in human blood. X. Contribution to succinylcholine cleavability and its possible relationship to atypical serum esterases].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1964, Volume: 339, Issue:1

    Topics: Acetylcholinesterase; Apnea; Blood Chemical Analysis; Humans; In Vitro Techniques; Succinylcholine

1964
Evaluation of intraperitoneal neomycin: effect of respiration in dogs under anesthesia.
    Annals of surgery, 1965, Volume: 162, Issue:4

    Topics: Anesthesia, Inhalation; Animals; Apnea; Calcium Chloride; Curare; Cyclopropanes; Dogs; Ethyl Ethers;

1965
[Incidence of atypical pseudocholinesterase in the Bantu population of the Congo].
    Acta anaesthesiologica Belgica, 1965, Volume: 16, Issue:1

    Topics: Apnea; Black or African American; Black People; Cholinesterases; Congo; Humans; In Vitro Techniques;

1965
[Prolonged apnea due to atypical pseudocholinesterase].
    Helvetica paediatrica acta, 1965, Volume: 20, Issue:6

    Topics: Anesthesia, General; Apnea; Child; Cholinesterases; Cyanosis; Female; Genetics, Medical; Humans; Mus

1965
[2 cases of prolonged apnea following administration of succinylcholine].
    Ospedali d'Italia - chirurgia, 1965, Volume: 13, Issue:6

    Topics: Adult; Apnea; Female; Humans; Succinylcholine

1965
[Succinylcholine-induced apnea and familial cholinesterase deficiency].
    Minerva anestesiologica, 1965, Volume: 31, Issue:12

    Topics: Adult; Apnea; Cholinesterases; Humans; In Vitro Techniques; Male; Metabolic Diseases; Succinylcholin

1965
[Resuscitative electric stimulation in prolonged apnea caused by electroshock in succinylcholine anesthesia].
    Minerva anestesiologica, 1965, Volume: 31, Issue:12

    Topics: Apnea; Electric Countershock; Electroconvulsive Therapy; Humans; Succinylcholine

1965
[Experimental investigations on the enzymatic reduction of C14 labeled succinyldicholine].
    Zentralblatt fur Chirurgie, 1965, Volume: 90, Issue:26

    Topics: Animals; Apnea; Carbon Isotopes; Enzymes; Humans; In Vitro Techniques; Injections, Intravenous; Para

1965
[Clinical study of succinylcholine on prolonged apnea].
    Masui. The Japanese journal of anesthesiology, 1965, Volume: 14, Issue:2

    Topics: Abdomen; Adult; Aged; Apnea; Blood; Cholinesterases; Humans; Middle Aged; Succinylcholine

1965
[Serum cholinesterase. Its significance in pulmonary diseases and bronchology].
    Zeitschrift fur Tuberkulose und Erkrankungen der Thoraxorgane, 1965, Volume: 123, Issue:4

    Topics: Apnea; Blood; Cholinesterases; Humans; Lung Diseases; Lung Neoplasms; Succinylcholine; Tuberculosis,

1965
Four families segregating for the silent gene for serum cholinesterase.
    Acta genetica et statistica medica, 1965, Volume: 15, Issue:3

    Topics: Adult; Apnea; Appendectomy; Child; Cholinesterases; Dibucaine; Enzymes; Female; Genes; Humans; Pulmo

1965
A silent pseudocholinesterase gene. Marked suxamethonium sensitivity in a person heterozygous for the atypical and silent pseudocholinesterase genes.
    Acta genetica et statistica medica, 1965, Volume: 15, Issue:3

    Topics: Apnea; Blood Chemical Analysis; Cholinesterases; Dibucaine; Enzymes; Fluorides; Genes; Humans; Middl

1965
Tendon reflexes as a guide to the safe use of succinylcholine in medicine.
    Canadian Psychiatric Association journal, 1966, Volume: 11 Suppl

    Topics: Apnea; Blood; Cholinesterases; Depression; Electroconvulsive Therapy; Humans; Neural Conduction; Neu

1966
Prolongation of the action of suxamethonium. A clinical investigation.
    Anaesthesia, 1966, Volume: 21, Issue:3

    Topics: Acridines; Anesthesia, Endotracheal; Apnea; Blood Chemical Analysis; Cholinesterases; Dibucaine; Enz

1966
Prolonged apnoea after suxamethonium injection associated with eye drops containing an anticholinesterase agent.
    British journal of anaesthesia, 1966, Volume: 38, Issue:5

    Topics: Aged; Anesthesia, Endotracheal; Apnea; Cholinesterase Inhibitors; Echothiophate Iodide; Female; Glau

1966
Suxamethonium apnoea. A study of eighteen cases.
    Anaesthesia, 1966, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Child; Child, Preschool; Cholinesterases; Dibuc

1966
A study of the pseudocholinesterase in 78 cases of apnoea following suxamethonium.
    Acta genetica et statistica medica, 1966, Volume: 16, Issue:3

    Topics: Apnea; Chlorides; Cholinesterases; Dibucaine; Drug Hypersensitivity; Fluorides; Genes; Humans; Succi

1966
A clinical and biochemical approach to cholinesterase problems in anesthesia.
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:6

    Topics: Anesthesia; Apnea; Cholinesterases; Succinylcholine

1966
Aversion treatment of alcoholics by succinylcholine-induced apneic paralysis.
    Quarterly journal of studies on alcohol, 1966, Volume: 27, Issue:3

    Topics: Adult; Alcoholism; Apnea; Conditioning, Operant; Conditioning, Psychological; Female; Humans; Male;

1966
[Hyperpyrexia during general anaesthesia: a case report].
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:5

    Topics: Adult; Anesthesia, General; Apnea; Bicarbonates; Decamethonium Compounds; Fever; Heart Massage; Huma

1966
[Prolonged apnea caused by atypical pseudocholinesterase].
    Der Anaesthesist, 1966, Volume: 15, Issue:3

    Topics: Adolescent; Anesthesia, General; Apnea; Appendectomy; Cholinesterases; Female; Homozygote; Humans; M

1966
[On bronchoscopy in general anesthesia].
    Der Anaesthesist, 1966, Volume: 15, Issue:11

    Topics: Acidosis, Respiratory; Adult; Aged; Anesthesia, General; Apnea; Bronchiectasis; Bronchoscopy; Carbon

1966