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succinylcholine and Amyotrophic Lateral Sclerosis

succinylcholine has been researched along with Amyotrophic Lateral Sclerosis in 6 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)

Research Excerpts

ExcerptRelevanceReference
"Three cases are reported where pre-existing medical conditions (severe osteoporosis, amyotrophic lateral sclerosis, cardiac arrhythmias) made the administration of succinylcholine during ECT potentially dangerous."3.69Substitution of mivacurium for succinylcholine for ECT in elderly patients. ( Fabian, JA; Gillis, M; Hess, J; Janis, K, 1995)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turner, MR1
Lawrence, H1
Arnold, I1
Ansorge, O1
Talbot, K1
ORNDAHL, G1
STENBERG, K1
Azar, I1
Janis, K1
Hess, J1
Fabian, JA1
Gillis, M1
Lundkvist, S1
Thomas, ET1
Dobkin, AB1

Reviews

1 review available for succinylcholine and Amyotrophic Lateral Sclerosis

ArticleYear
The response of patients with neuromuscular disorders to muscle relaxants: a review.
    Anesthesiology, 1984, Volume: 61, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Curare; Hemiplegia; Humans; Hyperkalemia; Malignant Hyperthermia; Mul

1984

Other Studies

5 other studies available for succinylcholine and Amyotrophic Lateral Sclerosis

ArticleYear
Catastrophic hyperkalaemia following administration of suxamethonium chloride to a patient with undiagnosed amyotrophic lateral sclerosis.
    Clinical medicine (London, England), 2011, Volume: 11, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Fasciculation; Fatal Outcome; Female; Humans; Hyperkalemia; Intubatio

2011
Myotonic human musculature: stimulation with depolarizing agents. Mechanical registration of the effects of succinyldicholine, succinylmonocholine and decamethonium.
    Acta medica Scandinavica. Supplementum, 1962, Volume: 389

    Topics: Amyotrophic Lateral Sclerosis; Decamethonium Compounds; Humans; Muscular Atrophy; Muscular Dystrophi

1962
Substitution of mivacurium for succinylcholine for ECT in elderly patients.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:7

    Topics: Aged; Amyotrophic Lateral Sclerosis; Contraindications; Electroconvulsive Therapy; Humans; Isoquinol

1995
Is there too little or too much cholinergic activity in amyotrophic lateral sclerosis?
    Medical hypotheses, 1988, Volume: 25, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Catalysis; Humans; Metals; Receptors, Cholinergic; Succinylcholine

1988
Untoward effects of muscle relaxant drugs.
    International anesthesiology clinics, 1972,Spring, Volume: 10, Issue:1

    Topics: Adjuvants, Anesthesia; Amyotrophic Lateral Sclerosis; Anesthesia, Inhalation; Anti-Bacterial Agents;

1972