Page last updated: 2024-11-04

succinylcholine and Alzheimer Disease

succinylcholine has been researched along with Alzheimer Disease in 4 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"A 75-years-old man with Alzheimer's disease, treated with the cholinesterase inhibitor donepezil for 14 months, was scheduled for left colectomy under general anesthesia."1.32[Interaction of donepezil and muscular blockers in Alzheimer's disease]. ( Demartini Ferrari, A; Roca de Togores López, A; Sánchez Morillo, J, 2003)
"Tacrine is a cholinesterase inhibitor used to manage Alzheimer's dementia."1.30Tacrine does not alter the potency of succinylcholine in the rat. ( Donati, F; Eshelby, D; Fox, GS; Ibebunjo, C; Tchervenkov, JI, 1997)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Russell, WJ1
Sánchez Morillo, J1
Demartini Ferrari, A1
Roca de Togores López, A1
Ibebunjo, C1
Eshelby, D1
Donati, F1
Fox, GS1
Tchervenkov, JI1
Heath, ML1

Other Studies

4 other studies available for succinylcholine and Alzheimer Disease

ArticleYear
The impact of Alzheimer's disease medication on muscle relaxants.
    Anaesthesia and intensive care, 2009, Volume: 37, Issue:1

    Topics: Alzheimer Disease; Androstanols; Cholinesterase Inhibitors; Donepezil; Drug Interactions; gamma-Cycl

2009
[Interaction of donepezil and muscular blockers in Alzheimer's disease].
    Revista espanola de anestesiologia y reanimacion, 2003, Volume: 50, Issue:2

    Topics: Acetylcholine; Aged; Alzheimer Disease; Anesthesia, General; Atracurium; Cholinesterase Inhibitors;

2003
Tacrine does not alter the potency of succinylcholine in the rat.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:9

    Topics: Administration, Oral; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Dose-Response Relations

1997
Donepezil, Alzheimer's disease and suxamethonium.
    Anaesthesia, 1997, Volume: 52, Issue:10

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Interactions; Humans; Indans; Neuromus

1997