Page last updated: 2024-11-04

succinylcholine and Acidosis

succinylcholine has been researched along with Acidosis in 48 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
"Two recent clinical reports suggested that succinylcholine (SCh) may cause severe hyperkalemia in hemorrhagic, acidotic humans."7.68Succinylcholine causes profound hyperkalemia in hemorrhagic, acidotic rabbits. ( Antognini, JF; Gronert, GA, 1993)
"Two recent clinical reports suggested that succinylcholine (SCh) may cause severe hyperkalemia in hemorrhagic, acidotic humans."3.68Succinylcholine causes profound hyperkalemia in hemorrhagic, acidotic rabbits. ( Antognini, JF; Gronert, GA, 1993)
" The treatment (ice packs, treatment of acidosis, glucose-insulin, methylprednisolone, lidocaine, verapamil, muscular relaxation and oxygen breathing) was effective."3.65[A further case of malignant hyperpyrexia and its treatment with lidocaine, methylprednisolone and verapamil (iproveratril) (author's transl)]. ( Bake, I; Buttazzoni, E; Csongrady, A; Pfänder, C; Schneider, M; Tarmann, H, 1976)
"Experiments in susceptible Landrace pigs have shown that procaine blocks the initiation of anaesthetic-induced malignant hyperpyrexia by both halothane and succinylcholine."3.65Anaesthetic-induced malignant hyperpyrexia: a suggested method of treatment. ( Harrison, GG, 1971)
"Succinylcholine was administered by infusion to halothane-anesthetized ponies to determine dosage requirements for surgical relaxation up to 3 hours' duration."1.27Succinylcholine infusion associated with hyperthermia in ponies anesthetized with halothane. ( Hildebrand, SV; Howitt, GA, 1983)
"The true incidence of malignant hyperthermia is unknown, but the frequency has been estimated as high as 1/14,000 anesthetic events."1.26Malignant hyperthermia. ( Nissen, RL; Yonkers, AJ, 1982)
"Pretreatment with procaine did not prevent the onset of the condition and the administration of procaine when muscle rigidity was present failed to prevent a fatal outcome."1.25Further studies of porcine malignant hyperthermia. ( Hall, LW; Trim, CM; Woolf, N, 1972)
"The methods used to screen patients for malignant hyperpyrexia at present are not sufficiently accurate."1.25Screening for malignant hyperpyrexia. ( Ellis, FR; Hargreaves, JB; Harriman, DG; Keaney, NP; Kyei-Mensah, K; Mulrooney, PL; Parikh, RK; Sumner, DW; Tyrrell, JH, 1972)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199045 (93.75)18.7374
1990's2 (4.17)18.2507
2000's0 (0.00)29.6817
2010's1 (2.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BACSA, S1
CZAKO, Z1
ARANYOSI, J1
BROOM, B1
SELLICK, BA1
Stephen, CR1
Nissen, RL1
Yonkers, AJ1
Hildebrand, SV1
Howitt, GA1
Antognini, JF1
Gronert, GA1
Moulds, RF1
Lippmann, M1
Nelson, RJ1
Emmanouilides, GC1
Diskin, J1
Thibeault, DW2
Brown, BR1
Walson, PD1
Taussig, LM1
Carballo, AS1
McGown, RG1
Csongrady, A1
Bake, I1
Pfänder, C1
Tarmann, H1
Schneider, M1
Buttazzoni, E1
Schwartz, DE1
Kelly, B1
Caldwell, JE1
Carlisle, AS1
Cohen, NH1
Wang, JJ1
Lee, JC1
Tzeng, JI1
Chan, JH1
Liu, SE1
Lee, TY1
Hughes, R1
Barrie, H1
Miller, G1
Furniss, P1
Slawson, KB1
Crul-Sluijter, EJ1
Crul, JF1
Purschke, R1
Zindler, M1
Newson, AJ1
Wasterlain, CG1
Lister, D1
Borchert, K1
Neumayer, E1
Stark, KH1
Franke, H1
Bull, AB1
Harrison, GG2
Samuel, JR1
Powell, D1
Hall, LW1
Trim, CM1
Woolf, N2
Ellis, FR1
Keaney, NP1
Harriman, DG1
Sumner, DW1
Kyei-Mensah, K1
Tyrrell, JH1
Hargreaves, JB1
Parikh, RK1
Mulrooney, PL1
Harpman, JA1
Hannah, HB1
Schmidt, W1
Werner, G1
Reske-Nielsen, E1
Kratholm, S1
Carson, SA1
Chorley, GE1
Hamilton, FN1
Lee, DC1
Morris, LE1
Ryan, JF1
Papper, EM1
James, OF1
Barlow, MB2
Isaacs, H2
Fox, GS1
Houle, GL1
Relton, JE1
Creighton, RE1
Conn, AW2
Greenburg, AG1
Kittle, CF1
Britt, BA1
Gordon, RA1
Mithoefer, JC1
Bossman, OG1
Daly, AM1
Irvin, GL1
Gittes, RF1
Gibbs, MF1

Reviews

1 review available for succinylcholine and Acidosis

ArticleYear
Anaesthesia for the patient in renal failure.
    British journal of anaesthesia, 1972, Volume: 44, Issue:3

    Topics: Acidosis; Anemia; Anesthesia; Anesthesia, Conduction; Anesthesia, Inhalation; Blood Pressure; Humans

1972

Other Studies

47 other studies available for succinylcholine and Acidosis

ArticleYear
JSA guideline for the management of malignant hyperthermia crisis 2016.
    Journal of anesthesia, 2017, Volume: 31, Issue:2

    Topics: Acidosis; Anesthetics, Inhalation; Body Temperature; Calcium; Carbon Dioxide; Dantrolene; Humans; Hy

2017
[COMPLICATIONS OF ANESTHESIA OVER A 10-YEAR PERIOD].
    Orvosi hetilap, 1963, Oct-20, Volume: 104

    Topics: Acidosis; Anesthesia; Anesthesia, Endotracheal; Anesthesia, Local; Anesthesiology; Barbiturates; Cur

1963
CONTROLLED HYPERCAPNIA IN OPEN HEART SURGERY UNDER HYPOTHERMIA.
    Lancet (London, England), 1965, Sep-04, Volume: 2, Issue:7410

    Topics: Acidosis; Blood Gas Analysis; Carbon Dioxide; Cardiac Surgical Procedures; Heart; Heart Septal Defec

1965
Fulminant hyperthermia during anesthesia and surgery.
    JAMA, 1967, Oct-16, Volume: 202, Issue:3

    Topics: Acidosis; Adolescent; Adult; Anesthesia, General; Animals; Cats; Child; Child, Preschool; Dogs; Fema

1967
Malignant hyperthermia.
    The Laryngoscope, 1982, Volume: 92, Issue:10 Pt 1

    Topics: Acidosis; Bicarbonates; Calcium; Creatine Kinase; Dantrolene; Diuretics; Fever; Humans; Malignant Hy

1982
Succinylcholine infusion associated with hyperthermia in ponies anesthetized with halothane.
    American journal of veterinary research, 1983, Volume: 44, Issue:12

    Topics: Acidosis; Anesthesia, Endotracheal; Animals; Halothane; Horse Diseases; Horses; Malignant Hypertherm

1983
Succinylcholine causes profound hyperkalemia in hemorrhagic, acidotic rabbits.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:3

    Topics: Acidosis; Animals; Hydrogen-Ion Concentration; Hyperkalemia; Rabbits; Shock, Hemorrhagic; Succinylch

1993
Letter: Malignant hyperpyrexia.
    Lancet (London, England), 1975, Mar-22, Volume: 1, Issue:7908

    Topics: Acidosis; Calcium; Catecholamines; Halothane; Humans; Insulin; Insulin Secretion; Malignant Hyperthe

1975
Ligation of patent ductus arteriosus in premature infants.
    British journal of anaesthesia, 1976, Volume: 48, Issue:4

    Topics: Acidosis; Aortography; Chylothorax; Ductus Arteriosus, Patent; Humans; Infant, Newborn; Infant, Prem

1976
Congenital metabolic diseases of pediatric patients: anesthetic implications.
    Anesthesiology, 1975, Volume: 43, Issue:2

    Topics: Acidosis; Anesthesia; Child; Cystic Fibrosis; Dysautonomia, Familial; Glycogen Storage Disease Type

1975
Aborted malignant hyperthermia: case report.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:2

    Topics: Acidosis; Adult; Anesthesia, General; Aspartate Aminotransferases; Bicarbonates; Creatine Kinase; Fe

1975
A technique of anaesthesia in haemorrhagic shock. Illustrative case histories and a discussion.
    Anaesthesia, 1975, Volume: 30, Issue:5

    Topics: Acidosis; Adolescent; Adult; Anesthesia, General; Atropine; Blood Pressure; Central Venous Pressure;

1975
[A further case of malignant hyperpyrexia and its treatment with lidocaine, methylprednisolone and verapamil (iproveratril) (author's transl)].
    Der Anaesthesist, 1976, Volume: 25, Issue:2

    Topics: Acidosis; Adult; Calcium; Cryotherapy; Glucose; Halothane; Humans; Insulin; Lidocaine; Male; Maligna

1976
Succinylcholine-induced hyperkalemic arrest in a patient with severe metabolic acidosis and exsanguinating hemorrhage.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:2

    Topics: Acidosis; Adult; Contraindications; Female; Heart Arrest; Humans; Hyperkalemia; Postpartum Hemorrhag

1992
[Hyperkalemia induced by succinylcholine injection in woman with metabolic acidosis].
    Ma zui xue za zhi = Anaesthesiologica Sinica, 1986, Volume: 24, Issue:4

    Topics: Acidosis; Adult; Female; Humans; Hyperkalemia; Malignant Hyperthermia; Succinylcholine

1986
Evaluation of the neuromuscular blocking properties and side-effects of the two new isoquinolinium bisquaternary compounds (BW.252C64 and BW.403C65).
    British journal of anaesthesia, 1972, Volume: 44, Issue:1

    Topics: Acidosis; Alkalosis; Anesthetics; Animals; Cats; Cholinesterase Inhibitors; Dogs; Gallamine Triethio

1972
Blood-gas tensions during apnoea in hyperbaric oxygen.
    Lancet (London, England), 1966, Dec-24, Volume: 2, Issue:7478

    Topics: Acidosis; Acidosis, Respiratory; Animals; Apnea; Asphyxia Neonatorum; Blood Gas Analysis; Humans; Hy

1966
The etiology of malignant hyperpyrexia.
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:2

    Topics: Acidosis; Adenosine Triphosphatases; Age Factors; Anesthesia, General; Animals; Body Temperature Reg

1971
Acidosis and neuromuscular blockade.
    Acta anaesthesiologica Scandinavica, 1974, Volume: 18, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Ascorbic Acid; Blood; Blood Pressure; Carbon Dioxide; Cats

1974
[Malignant hyperthermia--clinical aspects and treatment of life-endangering complications of anesthesia].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1974, Volume: 45, Issue:10

    Topics: Acidosis; Acute Kidney Injury; Anesthesia, General; Brain Edema; Calcium; Cell Membrane Permeability

1974
Malignant hyperthermia: current trends in treatment.
    The New Zealand medical journal, 1973, Volume: 77, Issue:489

    Topics: Acidosis; Bicarbonates; Clinical Enzyme Tests; Creatine Kinase; Cryosurgery; Humans; Hyperkalemia; M

1973
Mortality and morbidity from serial seizures. An experimental study.
    Epilepsia, 1974, Volume: 15, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Arrhythmias, Cardiac; Bicarbonates; Blood Pressure; Brain;

1974
Correction of adverse response to suxamethonium of susceptible pigs.
    British medical journal, 1973, Jan-27, Volume: 1, Issue:5847

    Topics: Acidosis; Animals; Body Temperature; Carbon Dioxide; Fever; Hydrogen-Ion Concentration; Succinylchol

1973
[Influence of succinylbischoline on the lactate and pyruvate levels].
    Zentralblatt fur Chirurgie, 1973, Jan-12, Volume: 98, Issue:2

    Topics: Acidosis; Adolescent; Adult; Bicarbonates; Blood Gas Analysis; Female; Humans; Hydrogen-Ion Concentr

1973
Recent advances in the understanding of anaesthetic-induced malignant hyperpyrexia.
    Acta anaesthesiologica Belgica, 1973, Volume: 24, Issue:2

    Topics: Acidosis; Anesthetics; Animals; Anura; Bicarbonates; Caffeine; Calcium; Cold Temperature; Disease Mo

1973
Renal transplantation. Anaesthetic experience of 100 cases.
    Anaesthesia, 1970, Volume: 25, Issue:2

    Topics: Acidosis; Adolescent; Adult; Anesthesia; Anesthetics; Female; Halothane; Heart Arrest; Humans; Kidne

1970
Further studies of porcine malignant hyperthermia.
    British medical journal, 1972, Apr-15, Volume: 2, Issue:5806

    Topics: Acidosis; Anesthesia, General; Anesthetics; Animals; Chloroform; Cyclopropanes; Fever; Halothane; Ke

1972
Screening for malignant hyperpyrexia.
    British medical journal, 1972, Sep-02, Volume: 3, Issue:5826

    Topics: Acidosis; Adolescent; Adult; Anesthesia, General; Biopsy; Child; Child, Preschool; Creatine Kinase;

1972
Anesthetic malignant myopathy hyperthermia.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1972, Volume: 96, Issue:3

    Topics: Acidosis; Adolescent; Anesthesia, Inhalation; Autopsy; Brain Edema; Cold Temperature; Female; Haloth

1972
A puzzling case of cardiac arrest.
    British journal of anaesthesia, 1971, Volume: 43, Issue:10

    Topics: Acidosis; Adult; Anesthesia, General; Appendectomy; Blood Pressure; Cryosurgery; Electrocardiography

1971
[Cardiac arrest after suxamethonium].
    Der Anaesthesist, 1971, Volume: 20, Issue:12

    Topics: Acidosis; Adult; Heart Arrest; Humans; Hyperkalemia; Kidney Failure, Chronic; Male; Sepsis; Succinyl

1971
Malignant hyperthermia. A fatal case provoked by anaesthesia in asymptomatic encephalitis?
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:4

    Topics: Acidosis; Anesthesia; Autopsy; Bicarbonates; Brain Edema; Central Nervous System; Child; Fever; Halo

1971
Variation in cardiac output with acid-base changes in the anesthetized dog.
    Journal of applied physiology, 1965, Volume: 20, Issue:5

    Topics: Acidosis; Acidosis, Respiratory; Animals; Apnea; Blood Circulation; Blood Gas Analysis; Carbon Dioxi

1965
Malignant fever during and following anesthesia.
    Anesthesiology, 1970, Volume: 32, Issue:3

    Topics: Acidosis; Adult; Anesthesia; Child, Preschool; Drug Hypersensitivity; Female; Fever; Humans; Male; M

1970
Hyperpyrexia and hypertonia in anaesthesia.
    The Medical journal of Australia, 1970, Jun-06, Volume: 1, Issue:23

    Topics: Acidosis; Adolescent; Alkaline Phosphatase; Anesthesia, Inhalation; Anesthetics; Appendectomy; Aspar

1970
"The stiff pig syndrome". An anaesthetic hazard.
    Clinical science, 1970, Volume: 39, Issue:1

    Topics: Acidosis; Anesthesia; Animals; Body Temperature; Halothane; Muscular Diseases; Succinylcholine; Swin

1970
Malignant hyperpyrexial deaths in a family. Reports of three cases.
    British journal of anaesthesia, 1970, Volume: 42, Issue:12

    Topics: Acidosis; Adult; Anesthesia, General; Child; Creatine Kinase; Female; Fever; Humans; Male; Muscles;

1970
The genetic background to malignant hyperpyrexia revealed by serum creatine phosphokinase estimations in asymptomatic relatives.
    British journal of anaesthesia, 1970, Volume: 42, Issue:12

    Topics: Acidosis; Adolescent; Adult; Aged; Anesthesia, General; Child; Child, Preschool; Creatine Kinase; Fe

1970
Acid-base studies in elective caesarean sections during epidural and general anaesthesia.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Anesthesia, Inhalation; Anesthesia, Obstetri

1971
Anaesthetic-induced malignant hyperpyrexia: a suggested method of treatment.
    British medical journal, 1971, Volume: 3, Issue:5772

    Topics: Acidosis; Anesthesia, General; Animals; Bicarbonates; Curare; Fever; Halothane; Procaine; Succinylch

1971
Fulminant hyperpyrexia associated with anaesthesia.
    Anaesthesia, 1968, Volume: 23, Issue:2

    Topics: Acidosis; Acidosis, Respiratory; Anesthesia, Endotracheal; Anesthesia, General; Anesthesia, Intraven

1968
The effects of acute changes in acid-base status on coronary blood flow.
    Surgery, 1968, Volume: 64, Issue:1

    Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Animals; Bicarbonates; Blood Flow

1968
Three cases of malignant hyperthermia with special consideration of management.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:2

    Topics: Acidosis; Adult; Anesthesia, Inhalation; Child, Preschool; Female; Fever; Halothane; Humans; Hyperka

1969
The effect of metabolic acidosis on the CO2 titration curve.
    Anesthesiology, 1969, Volume: 30, Issue:4

    Topics: Acidosis; Acidosis, Respiratory; Anesthesia, General; Animals; Bicarbonates; Buffers; Dogs; Homeosta

1969
Anaesthesia for pyloromyotomy: a review (the Hospital for Sick Children, Toronto).
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:4

    Topics: Acidosis; Alkalosis; Anesthesia, General; Anesthesia, Inhalation; Atropine; Dehydration; Ethers; Eth

1969
Influence of acid-base disturbances on total plasma calcium and evidence for a homeostatic role of thyrocalcitonin.
    Annals of surgery, 1966, Volume: 164, Issue:6

    Topics: Acidosis; Alkalosis; Animals; Calcitonin; Hydrogen-Ion Concentration; Hypercalcemia; Paralysis; Para

1966
[Malignant hyperpyrexia during general anaesthesia].
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:5

    Topics: Acidosis; Adult; Anesthesia, General; Child; Fever; Halothane; Humans; Hypothermia, Induced; Methoxy

1966