succinylacetone has been researched along with Nerve Degeneration in 1 studies
succinylacetone: inhibitor of heme biosynthesis
4,6-dioxoheptanoic acid : A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Defective heme synthesis may cause acute porphyrias, which are associated with a wide array of neurological disturbances involving both the central and peripheral nervous systems." | 3.73 | Heme deficiency suppresses the expression of key neuronal genes and causes neuronal cell death. ( Hon, T; Sengupta, A; Zhang, L, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sengupta, A | 1 |
| Hon, T | 1 |
| Zhang, L | 1 |
1 other study available for succinylacetone and Nerve Degeneration
| Article | Year |
|---|---|
Heme deficiency suppresses the expression of key neuronal genes and causes neuronal cell death.
Topics: Animals; Apoptosis; Caspases; Cell Survival; Collagen Type XI; Cyclic AMP Response Element-Binding P | 2005 |