succinylacetone has been researched along with Metabolism, Inborn Errors in 4 studies
succinylacetone: inhibitor of heme biosynthesis
4,6-dioxoheptanoic acid : A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
Metabolism, Inborn Errors: Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Screening for Tyrosinemia type 1 using tandem mass spectrometry measurement of succinylacetone from dried blood spots appears to be promising." | 2.55 | Newborn screening for Tyrosinemia type 1 using succinylacetone - a systematic review of test accuracy. ( Clarke, A; Fraser, H; Freeman, K; Geppert, J; Johnson, S; Stinton, C; Sutcliffe, P; Taylor-Phillips, S, 2017) |
| "Newborn screening for tyrosinemia type I (Tyr-I) is mandatory to identify infants at risk before life-threatening symptoms occur." | 1.38 | Evaluation of a novel, commercially available mass spectrometry kit for newborn screening including succinylacetone without hydrazine. ( Gottschalk, A; Herkner, KR; Kasper, DC; Lukačin, R; Mechtler, TP; Merk, M; Metz, TF, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Céspedes, N | 1 |
| Valencia, A | 1 |
| Echeverry, CA | 1 |
| Arce-Plata, MI | 1 |
| Colón, C | 1 |
| Castiñeiras, DE | 1 |
| Hurtado, PM | 1 |
| Cocho, JA | 1 |
| Herrera, S | 1 |
| Arévalo-Herrera, M | 1 |
| Stinton, C | 1 |
| Geppert, J | 1 |
| Freeman, K | 1 |
| Clarke, A | 1 |
| Johnson, S | 1 |
| Fraser, H | 1 |
| Sutcliffe, P | 1 |
| Taylor-Phillips, S | 1 |
| Metz, TF | 1 |
| Mechtler, TP | 1 |
| Merk, M | 1 |
| Gottschalk, A | 1 |
| Lukačin, R | 1 |
| Herkner, KR | 1 |
| Kasper, DC | 1 |
| Gagné, R | 1 |
| Lescault, A | 1 |
| Grenier, A | 1 |
| Laberge, C | 1 |
| Mélançon, SB | 1 |
| Dallaire, L | 1 |
1 review available for succinylacetone and Metabolism, Inborn Errors
| Article | Year |
|---|---|
Newborn screening for Tyrosinemia type 1 using succinylacetone - a systematic review of test accuracy.
Topics: Heptanoates; Humans; Infant, Newborn; Metabolism, Inborn Errors; Neonatal Screening; Tandem Mass Spe | 2017 |
3 other studies available for succinylacetone and Metabolism, Inborn Errors
| Article | Year |
|---|---|
Reference values of amino acids, acylcarnitines and succinylacetone by tandem mass spectrometry for use in newborn screening in southwest Colombia.
Topics: Amino Acids; Biomarkers; Carnitine; Colombia; Cross-Sectional Studies; False Positive Reactions; Hep | 2017 |
Evaluation of a novel, commercially available mass spectrometry kit for newborn screening including succinylacetone without hydrazine.
Topics: Dried Blood Spot Testing; Heptanoates; Humans; Hydrazines; Infant, Newborn; Mass Spectrometry; Metab | 2012 |
Prenatal diagnosis of hereditary tyrosinaemia: measurement of succinylacetone in amniotic fluid.
Topics: Amniotic Fluid; Female; Genes, Recessive; Heptanoates; Heptanoic Acids; Humans; Hydrolases; Liver; M | 1982 |