succinylacetone has been researched along with Liver Failure in 4 studies
succinylacetone: inhibitor of heme biosynthesis
4,6-dioxoheptanoic acid : A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Results of NTBC therapy used in three infants with type I tyrosinemia who presented with acute liver failure are reported." | 3.70 | [Favorable outcome of treatment with NTBC of acute liver insufficiency disclosing hereditary tyrosinemia type I]. ( Barkaoui, E; Bernard, O; Debray, D; Habès, D; Ogier, H, 1999) |
| "Hereditary tyrosinemia type I (HT-I) is an autosomal recessive inborn error of tyrosine metabolism, caused by mutation(s) in the gene encoding for fumarylacetoacetate hydrolase (FAH) enzyme." | 1.37 | Long-term outcome of living donor liver transplantation in a Thai boy with hereditary tyrosinemia type I: a case report. ( Jitraruch, S; Leelaudomlipi, S; Sornmayura, P; Sriphojanart, S; Teeraratkul, S; Treepongkaruna, S; Viengteerawat, S; Wattanasirichaigoon, D, 2011) |
| "To confirm the diagnosis of tyrosinemia, quantitative urinary succinylacetone was measured." | 1.31 | [Liver failure with coagulopathy in an infant with tyrosinemia]. ( Amir, J; Campino, G; Nussinovitch, M; Shapira, R; Voluvitz, B, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jitraruch, S | 1 |
| Treepongkaruna, S | 1 |
| Teeraratkul, S | 1 |
| Wattanasirichaigoon, D | 1 |
| Leelaudomlipi, S | 1 |
| Sornmayura, P | 1 |
| Viengteerawat, S | 1 |
| Sriphojanart, S | 1 |
| Bruneau, N | 1 |
| St-Vil, D | 1 |
| Luks, FI | 1 |
| LaBerge, JM | 1 |
| Bensoussan, AL | 1 |
| Blanchard, H | 1 |
| Barkaoui, E | 1 |
| Debray, D | 1 |
| Habès, D | 1 |
| Ogier, H | 1 |
| Bernard, O | 1 |
| Nussinovitch, M | 1 |
| Campino, G | 1 |
| Shapira, R | 1 |
| Voluvitz, B | 1 |
| Amir, J | 1 |
4 other studies available for succinylacetone and Liver Failure
| Article | Year |
|---|---|
Long-term outcome of living donor liver transplantation in a Thai boy with hereditary tyrosinemia type I: a case report.
Topics: Asian People; Diet Therapy; Heptanoates; Humans; Hydrolases; Infant; Liver Failure; Liver Transplant | 2011 |
[Surgical and metabolic aspects of liver transplantation for tyrosinemia].
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Central Nervous System Diseas | 1993 |
[Favorable outcome of treatment with NTBC of acute liver insufficiency disclosing hereditary tyrosinemia type I].
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Acute Disease; Amino Acid Metabolism, Inborn Errors; Aminolevul | 1999 |
[Liver failure with coagulopathy in an infant with tyrosinemia].
Topics: Biomarkers; Disseminated Intravascular Coagulation; Heptanoates; Humans; Infant; Liver Failure; Male | 2001 |