succinylacetone has been researched along with Leukemia, Myeloid in 2 studies
succinylacetone: inhibitor of heme biosynthesis
4,6-dioxoheptanoic acid : A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
Leukemia, Myeloid: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, L | 1 |
| Zhen, L | 1 |
| Dinauer, MC | 1 |
| Castañeda, VL | 1 |
| Parmley, RT | 1 |
| Pinnix, IB | 1 |
| Raju, SG | 1 |
| Guzman, GS | 1 |
| Kinkade, JM | 1 |
2 other studies available for succinylacetone and Leukemia, Myeloid
| Article | Year |
|---|---|
Biosynthesis of the phagocyte NADPH oxidase cytochrome b558. Role of heme incorporation and heterodimer formation in maturation and stability of gp91phox and p22phox subunits.
Topics: 3T3 Cells; Animals; Cell Differentiation; Cell Membrane; COS Cells; Cytochrome b Group; Dimerization | 1997 |
Ultrastructural, immunochemical, and cytochemical study of myeloperoxidase in myeloid leukemia HL-60 cells following treatment with succinylacetone, an inhibitor of heme biosynthesis.
Topics: Heme; Heptanoates; Histocytochemistry; Humans; Immunohistochemistry; Leukemia, Myeloid; Microscopy, | 1992 |