succinylacetone has been researched along with Experimental Leukemia in 3 studies
succinylacetone: inhibitor of heme biosynthesis
4,6-dioxoheptanoic acid : A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebert, PS | 2 |
| Frykholm, BC | 2 |
| Hess, RA | 2 |
| Tschudy, DP | 2 |
| Sasaki, D | 1 |
| Kosunago, S | 1 |
| Hirano, J | 1 |
| Matsuda, K | 1 |
| Hata, Y | 1 |
| Komiyama, Y | 1 |
| Mikami, T | 1 |
| Matsumoto, T | 1 |
| Suzuki, M | 1 |
3 other studies available for succinylacetone and Experimental Leukemia
| Article | Year |
|---|---|
Uptake of hematin and growth of malignant murine erythroleukemia cells depleted of endogenous heme by succinylacetone.
Topics: 5-Aminolevulinate Synthetase; Animals; Biological Transport; Cell Division; Heme; Hemin; Heptanoates | 1981 |
Cloning and characterization of K562 cells on hemoglobin synthetic activity.
Topics: Antigens, CD; Antigens, Surface; Cell Cycle; Cell Differentiation; Clone Cells; Glycophorins; Hemogl | 1993 |
Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme content and delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells.
Topics: Animals; Cell Division; Cells, Cultured; Heme; Hemoglobins; Heptanoates; Heptanoic Acids; Keto Acids | 1979 |