succinylacetone has been researched along with Adult Fanconi Syndrome in 9 studies
succinylacetone: inhibitor of heme biosynthesis
4,6-dioxoheptanoic acid : A dioxo monocarboxylic acid that is heptanoic acid in which oxo groups replace the hydrogens at positions 4 and 6. It is an abnormal metabolite of the tyrosine metabolic pathway and a marker for type 1 tyrosinaemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1." | 1.28 | Physiological basis for an animal model of the renal Fanconi syndrome: use of succinylacetone in the rat. ( Boynton, SB; Chu, J; Roth, KS; Spencer, RF; Wyss, PA, 1992) |
| "Succinylacetone (SA) is a known inhibitor of the heme biosynthetic pathway in liver." | 1.28 | delta-Aminolevulinic acid dehydratase: effects of succinylacetone in rat liver and kidney in an in vivo model of the renal Fanconi syndrome. ( Carter, BE; Roth, KS; Wyss, PA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wyss, PA | 2 |
| Boynton, SB | 1 |
| Chu, J | 1 |
| Spencer, RF | 2 |
| Roth, KS | 9 |
| Carter, BE | 3 |
| Higgins, ES | 2 |
| Moses, LC | 3 |
| Spencer, PD | 5 |
| Medow, MS | 2 |
| Schwarz, SM | 1 |
| Foreman, JW | 1 |
1 review available for succinylacetone and Adult Fanconi Syndrome
| Article | Year |
|---|---|
Human renal Fanconi syndrome--then and now.
Topics: Animals; Cystinosis; Disease Models, Animal; Dogs; Fanconi Syndrome; Heptanoates; Humans; Maleates | 1989 |
8 other studies available for succinylacetone and Adult Fanconi Syndrome
| Article | Year |
|---|---|
Physiological basis for an animal model of the renal Fanconi syndrome: use of succinylacetone in the rat.
Topics: Amino Acids; Animals; Creatinine; Disease Models, Animal; Fanconi Syndrome; Glucose; Heptanoates; Ki | 1992 |
delta-Aminolevulinic acid dehydratase: effects of succinylacetone in rat liver and kidney in an in vivo model of the renal Fanconi syndrome.
Topics: Animals; Fanconi Syndrome; Heptanoates; Kidney; Liver; Male; Organ Specificity; Porphobilinogen Synt | 1992 |
Succinylacetone effects on renal tubular phosphate metabolism: a model for experimental renal Fanconi syndrome.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Disease Models, Animal; Fanconi Syndrome; Glutamat | 1991 |
On rat renal aminolevulinate transport and metabolism in experimental Fanconi syndrome.
Topics: Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Animals; Biological Transport, Active; Fa | 1990 |
Renal Fanconi syndrome: developmental basis for a new animal model with relevance to human disease.
Topics: Amino Acids; Animals; Animals, Newborn; Biological Transport; Carbohydrate Metabolism; Disease Model | 1989 |
Effects of succinylacetone on the uptake of sugars and amino acids by brush border vesicles.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Biological Transport; Carbohydrate Metab | 1988 |
Effects of succinylacetone on amino acid uptake in the rat kidney.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Fanconi Syndrome; Heptanoates; Heptanoic Acids; In Vitr | 1987 |
Effects of succinylacetone on methyl alpha-D-glucoside uptake by the rat renal tubule.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Fanconi Syndrome; Heptanoates; Heptanoic Ac | 1985 |