succinoglycan has been researched along with Hypercholesterolemia* in 1 studies
1 other study(ies) available for succinoglycan and Hypercholesterolemia
Article | Year |
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Oral Administration of Succinoglycan Riclin Improves Diet-Induced Hypercholesterolemia in Mice.
Epidemiological studies have demonstrated that hypercholesterolemia is associated with an elevated risk of atherosclerosis and cardiovascular diseases. In addition to the available cholesterol-lowering drugs, nutritionally balanced diets containing functional foods have attracted much interest as potential candidates to improve hypercholesterolemia. In the study, we demonstrated that dietary succinoglycan riclin effectively alleviated diet-induced hypercholesterolemia. Compared with the high-cholesterol-diet (HCD) group, the high-riclin group significantly decreased levels of the serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), and hepatic cholesterol (34, 40, and 51%, respectively), consequently improving hepatic steatosis and reducing proinflammatory cytokine expressions. Topics: Animals; Anticholesteremic Agents; Bile Acids and Salts; Cholesterol, LDL; Diet, High-Fat; Humans; Hypercholesterolemia; Liver; Male; Mice; Mice, Inbred C57BL; Polysaccharides, Bacterial | 2019 |