succinic acid has been researched along with Vitamin B 12 Deficiency in 3 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Vitamin B 12 Deficiency: A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)
Excerpt | Relevance | Reference |
---|---|---|
"Some patients with pernicious anemia who were intermittently treated with cyanocobalamin were found to have elevated serum levels of methylmalonic acid while free of hematologic and neurologic abnormalities." | 1.27 | Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry. ( Allen, RH; Lindenbaum, J; Marcell, PD; Podell, ER; Stabler, SP, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (33.33) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kennedy, DG | 1 |
Young, PB | 1 |
McCaughey, WJ | 1 |
Kennedy, S | 1 |
Blanchflower, WJ | 1 |
Stabler, SP | 2 |
Allen, RH | 2 |
Barrett, RE | 1 |
Savage, DG | 1 |
Lindenbaum, J | 2 |
Marcell, PD | 1 |
Podell, ER | 1 |
3 other studies available for succinic acid and Vitamin B 12 Deficiency
Article | Year |
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Rumen succinate production may ameliorate the effects of cobalt-vitamin B-12 deficiency on methylmalonyl CoA mutase in sheep.
Topics: Absorption; Androstadienes; Animals; Cobalt; Fluticasone; Gluconeogenesis; Methylmalonic Acid; Methy | 1991 |
Cerebrospinal fluid methylmalonic acid levels in normal subjects and patients with cobalamin deficiency.
Topics: Adult; Aged; Female; Humans; Male; Methylmalonic Acid; Middle Aged; Succinates; Succinic Acid; Vitam | 1991 |
Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry.
Topics: Adolescent; Adult; Aged; Anemia, Pernicious; Female; Folic Acid; Gas Chromatography-Mass Spectrometr | 1986 |