succinic acid has been researched along with Nephrotic Syndrome in 1 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As part of our continuing work to obtain new pro-drugs for the treatment of nephropathic cystinosis, a number of glutaric and succinic acid derivatives of cystamine have been designed, synthesised and biologically evaluated in vitro." | 3.77 | Synthesis and in vitro evaluation of novel pro-drugs for the treatment of nephropathic cystinosis. ( Benylles, A; Cairns, D; Kay, G; Knott, RM; Moloney, KA; Omran, Z, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Omran, Z | 1 |
| Moloney, KA | 1 |
| Benylles, A | 1 |
| Kay, G | 1 |
| Knott, RM | 1 |
| Cairns, D | 1 |
1 other study available for succinic acid and Nephrotic Syndrome
| Article | Year |
|---|---|
Synthesis and in vitro evaluation of novel pro-drugs for the treatment of nephropathic cystinosis.
Topics: Cystamine; Cystinosis; Fanconi Syndrome; Fibroblasts; Glutarates; Humans; Nephrotic Syndrome; Prodru | 2011 |