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succinic acid and Nephrotic Syndrome

succinic acid has been researched along with Nephrotic Syndrome in 1 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
"As part of our continuing work to obtain new pro-drugs for the treatment of nephropathic cystinosis, a number of glutaric and succinic acid derivatives of cystamine have been designed, synthesised and biologically evaluated in vitro."3.77Synthesis and in vitro evaluation of novel pro-drugs for the treatment of nephropathic cystinosis. ( Benylles, A; Cairns, D; Kay, G; Knott, RM; Moloney, KA; Omran, Z, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Omran, Z1
Moloney, KA1
Benylles, A1
Kay, G1
Knott, RM1
Cairns, D1

Other Studies

1 other study available for succinic acid and Nephrotic Syndrome

ArticleYear
Synthesis and in vitro evaluation of novel pro-drugs for the treatment of nephropathic cystinosis.
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Cystamine; Cystinosis; Fanconi Syndrome; Fibroblasts; Glutarates; Humans; Nephrotic Syndrome; Prodru

2011