succinic acid has been researched along with Neoplasms in 33 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent reports indicate that cancer-secreted succinate enhances cancer cell migration and promotes cancer metastasis by activating succinate receptor-1 (SUCNR-1)-mediated signaling and transcription pathways." | 2.82 | Cancer-derived extracellular succinate: a driver of cancer metastasis. ( Kuo, CC; Wu, JY; Wu, KK, 2022) |
| "Lysine succinylation is a novel, broad-spectrum, dynamic, non-enzymatic protein post-translational modification (PTM)." | 2.82 | A review of the mechanism of succinylation in cancer. ( Han, D; Lu, K, 2022) |
| "Metabolic reprogramming in cancer cells entails activities that involve several enzymes and metabolites to convert nutrient into building blocks that alter energy metabolism to fuel rapid cell division." | 2.66 | Cancer Cell Metabolites: Updates on Current Tracing Methods. ( Maniam, S, 2020) |
| "In solid tumors, the microenvironment is often immunosuppressive and hypoxic regions are prevalent." | 2.66 | Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumors. ( Griffioen, AW; Huijbers, EJM; Kes, MMG; Van den Bossche, J, 2020) |
| "Silencing of PLOD2 expression in breast cancer cells reduced succinate levels and inhibited cancer cell mesenchymal phenotypes and stemness, which was accompanied by elevated 5hmC levels in chromatin." | 1.91 | The PLOD2/succinate axis regulates the epithelial-mesenchymal plasticity and cancer cell stemness. ( Chen, J; He, D; Lane, AN; Li, J; Li, L; Qi, Y; Scott, TL; Tong, Y; Wang, C; Xiong, G; Xu, R, 2023) |
| "Succinic acid is a potential biomarker of SDH related pathologies for diagnostic, evaluation of treatment response and follow-up of the disease." | 1.72 | Quantification of succinic acid levels, linked to succinate dehydrogenase (SDH) dysfunctions, by an automated and fully validated liquid chromatography tandem mass spectrometry method suitable for multi-matrix applications. ( Blondel, L; Broutin, S; Lamy, C; Mansard, C; Mercier, L; Paci, A, 2022) |
| "Here, we established SDHB knockout cancer cell lines from human colon cancer HCT116 cells using the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 knockout system, and clarified its metabolic characteristics." | 1.46 | Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. ( Ando, A; Baba, Y; Ebara, S; Hara, T; Kitazawa, S; Satomi, Y; Soga, T, 2017) |
| "In exercise, as well as cancer and ischemia, hypoxia-inducible factor 1 (HIF1) transcriptionally activates hundreds of genes vital for cell homeostasis and angiogenesis." | 1.35 | Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. ( Popel, AS; Qutub, AA, 2008) |
| "Targeted cancer therapy is a promising strategy for the treatment of this disease." | 1.33 | Synthesis and biological evaluation of a paclitaxel immunoconjugate. ( Raisch, KP; Safavy, A, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (15.15) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 12 (36.36) | 24.3611 |
| 2020's | 12 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Lamy, C | 1 |
| Mansard, C | 1 |
| Blondel, L | 1 |
| Mercier, L | 1 |
| Paci, A | 1 |
| Broutin, S | 1 |
| Elia, I | 1 |
| Rowe, JH | 1 |
| Johnson, S | 1 |
| Joshi, S | 1 |
| Notarangelo, G | 1 |
| Kurmi, K | 1 |
| Weiss, S | 1 |
| Freeman, GJ | 1 |
| Sharpe, AH | 1 |
| Haigis, MC | 1 |
| Kuo, CC | 1 |
| Wu, JY | 1 |
| Wu, KK | 1 |
| Lu, K | 4 |
| Han, D | 3 |
| Liu, Y | 5 |
| Liu, K | 1 |
| Thorne, RF | 1 |
| Shi, R | 1 |
| Zhang, Q | 3 |
| Wu, M | 3 |
| Liu, L | 3 |
| Tong, Y | 1 |
| Qi, Y | 2 |
| Xiong, G | 1 |
| Li, J | 8 |
| Scott, TL | 1 |
| Chen, J | 2 |
| He, D | 1 |
| Li, L | 1 |
| Wang, C | 4 |
| Lane, AN | 1 |
| Xu, R | 1 |
| Chen, F | 2 |
| Dowerg, B | 1 |
| Cordes, T | 1 |
| Maniam, S | 2 |
| Ning, W | 1 |
| Xu, H | 1 |
| Jiang, P | 1 |
| Cheng, H | 1 |
| Deng, W | 1 |
| Guo, Y | 1 |
| Xue, Y | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 11 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
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| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
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| Rasool, G | 1 |
| Irfan, M | 1 |
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| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Zhang, S | 2 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
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| Sajo, EA | 1 |
| Okunade, KS | 1 |
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| Dong, X | 1 |
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| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 3 |
| Li, Y | 5 |
| Xue, F | 1 |
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| Meng, J | 1 |
| Chen, G | 2 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Li, P | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Zhou, X | 2 |
| Wang, W | 1 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 1 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 1 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
| Ji, H | 1 |
| Yang, X | 2 |
| Xu, Z | 1 |
| Wan, L | 1 |
| Wen, Q | 1 |
| Cho, CH | 1 |
| Zou, C | 1 |
| Xiao, Z | 1 |
| Liao, J | 1 |
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| Huang, H | 1 |
| Wei, Y | 2 |
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| Na, KJ | 1 |
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| Lee, DS | 1 |
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| Pajuelo-Lozano, N | 1 |
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| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
| Richter, C | 1 |
| Edelhäuser, BAH | 1 |
| Engelmann, D | 1 |
| Brenmoehl, J | 1 |
| Söhnchen, C | 1 |
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| Alpers, M | 1 |
| Singh, KP | 1 |
| Wolkenhauer, O | 1 |
| Heckl, D | 1 |
| Spitschak, A | 1 |
| Pützer, BM | 1 |
| Liao, Y | 1 |
| Cheng, J | 1 |
| Kong, X | 1 |
| Li, S | 2 |
| Zhang, M | 4 |
| Zhang, H | 1 |
| Yang, T | 2 |
| Dong, Y | 1 |
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| Cao, J | 2 |
| Zheng, Y | 1 |
| Luo, Z | 1 |
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| Liu, Z | 2 |
| Liang, C | 1 |
| Yang, H | 1 |
| Song, Y | 1 |
| Yu, K | 1 |
| Zhu, C | 1 |
| Huang, Z | 1 |
| Qian, J | 1 |
| Ge, J | 1 |
| Hu, J | 2 |
| Wang, H | 2 |
| Mi, Y | 1 |
| Kong, H | 1 |
| Xi, D | 1 |
| Yan, W | 2 |
| Luo, X | 1 |
| Ning, Q | 1 |
| Chang, X | 2 |
| Zhang, T | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
| Reddy, K | 1 |
| Chen, H | 1 |
| Shin, SH | 1 |
| Ma, WY | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Mu, W | 1 |
| Liu, C | 3 |
| Gao, F | 1 |
| Lu, H | 1 |
| Zhang, X | 4 |
| Cai, X | 1 |
| Ji, RY | 1 |
| Hou, Y | 3 |
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| Shi, Y | 1 |
| Ying, S | 1 |
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| Feng, G | 1 |
| Kuang, Y | 1 |
| Chen, D | 1 |
| Wu, D | 3 |
| Zhu, ZQ | 1 |
| Tang, HX | 1 |
| Shi, ZE | 1 |
| Kang, J | 1 |
| Liu, Q | 1 |
| Qi, J | 2 |
| Mu, J | 1 |
| Cong, Z | 1 |
| Chen, S | 2 |
| Fu, D | 1 |
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| Celestrin, CP | 1 |
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| Guadagnini, D | 1 |
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| Saad, MJA | 1 |
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| Lu, Y | 1 |
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| Li, C | 1 |
| Chen, W | 2 |
| Hu, X | 1 |
| Zhang, F | 1 |
| Wei, H | 1 |
| Wang, Z | 1 |
| Gurzu, S | 1 |
| Jung, I | 1 |
| Sugimura, H | 2 |
| Stefan-van Staden, RI | 1 |
| Yamada, H | 1 |
| Natsume, H | 1 |
| Iwashita, Y | 1 |
| Szodorai, R | 1 |
| Szederjesi, J | 1 |
| Yari, D | 1 |
| Ehsanbakhsh, Z | 1 |
| Validad, MH | 1 |
| Langroudi, FH | 1 |
| Esfandiari, H | 1 |
| Prager, A | 1 |
| Hassanpour, K | 1 |
| Kurup, SP | 1 |
| Mets-Halgrimson, R | 1 |
| Yoon, H | 1 |
| Zeid, JL | 1 |
| Mets, MB | 1 |
| Rahmani, B | 1 |
| Araujo-Castillo, RV | 1 |
| Culquichicón, C | 1 |
| Solis Condor, R | 1 |
| Efendi, F | 1 |
| Sebayang, SK | 1 |
| Astutik, E | 1 |
| Hadisuyatmana, S | 1 |
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| Perez-Padilla, R | 1 |
| Jarvis, D | 1 |
| de Oliveira, PD | 1 |
| Wehrmeister, FC | 1 |
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| Wong, J | 1 |
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| Bellingham, G | 1 |
| Singh, M | 2 |
| Waseem, R | 1 |
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| Chung, F | 1 |
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| Goetchius, E | 1 |
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| Ryder, JW | 1 |
| Ploutz-Snyder, R | 1 |
| Guilliams, M | 1 |
| Scott, JM | 1 |
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| Martens, C | 1 |
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| Aasen, T | 1 |
| Gjestad, R | 1 |
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| Nordahl, SHG | 1 |
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| Soshi, S | 1 |
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| Mortensen, NP | 1 |
| Caffaro, MM | 1 |
| Patel, PR | 2 |
| Uddin, MJ | 1 |
| Aravamudhan, S | 1 |
| Sumner, SJ | 1 |
| Fennell, TR | 1 |
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| Bergenstal, RM | 1 |
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| Haban, A | 1 |
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| Johnson, ML | 1 |
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15 reviews available for succinic acid and Neoplasms
| Article | Year |
|---|---|
Cancer-derived extracellular succinate: a driver of cancer metastasis.
Topics: Extracellular Space; Humans; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Paragan | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
A review of the mechanism of succinylation in cancer.
Topics: Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Signal Transduction; Succinic Aci | 2022 |
The yin and yang of itaconate metabolism and its impact on the tumor microenvironment.
Topics: Humans; Neoplasms; Succinates; Succinic Acid; Tumor Microenvironment | 2023 |
Cancer Cell Metabolites: Updates on Current Tracing Methods.
Topics: Amino Acids; Citric Acid; Glucose; Glycine; Humans; Isotope Labeling; Lactic Acid; Neoplasms; Succin | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Oncometabolites lactate and succinate drive pro-angiogenic macrophage response in tumors.
Topics: Angiogenesis Inhibitors; Cell Hypoxia; Cellular Reprogramming; Drug Resistance, Neoplasm; Humans; La | 2020 |
Oncometabolites: A New Paradigm for Oncology, Metabolism, and the Clinical Laboratory.
Topics: Animals; Clinical Laboratory Services; Fumarates; Glutarates; Humans; Metabolic Networks and Pathway | 2017 |
The role of metabolic enzymes in mesenchymal tumors and tumor syndromes: genetics, pathology, and molecular mechanisms.
Topics: Animals; Fumarate Hydratase; Fumarates; Glutarates; Humans; Isocitrate Dehydrogenase; Mixed Function | 2018 |
Coupling Krebs cycle metabolites to signalling in immunity and cancer.
Topics: Citric Acid Cycle; Humans; Immunity, Innate; Macrophages; Neoplasms; Signal Transduction; Succinate | 2019 |
Regulation of succinate dehydrogenase and role of succinate in cancer.
Topics: Animals; Epithelial-Mesenchymal Transition; Humans; Neoplasms; Succinate Dehydrogenase; Succinic Aci | 2020 |
The Warburg effect then and now: from cancer to inflammatory diseases.
Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Citr | 2013 |
Nanoparticles consisting of tocopheryl succinate are a novel drug-delivery system with multifaceted antitumor activity.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Delivery System | 2014 |
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
Topics: Carcinogenesis; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, | 2016 |
Succinate in the cancer-immune cycle.
Topics: Citric Acid Cycle; Humans; Inflammation; Neoplasms; Succinic Acid | 2017 |
Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death.
Topics: alpha-Tocopherol; Cell Death; Coenzyme A; Dihydrolipoamide Dehydrogenase; Fatty Acids, Nonesterified | 2011 |
2 trials available for succinic acid and Neoplasms
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
A randomized clinical trial of induction therapy with OKT3 in kidney transplantation.
Topics: Adolescent; Adult; Aged; Antibody Formation; Azathioprine; Child; Cyclosporine; Drug Administration | 1993 |
17 other studies available for succinic acid and Neoplasms
| Article | Year |
|---|---|
Quantification of succinic acid levels, linked to succinate dehydrogenase (SDH) dysfunctions, by an automated and fully validated liquid chromatography tandem mass spectrometry method suitable for multi-matrix applications.
Topics: Biomarkers, Tumor; Chromatography, Liquid; Humans; Limit of Detection; Linear Models; Neoplasms; Rep | 2022 |
Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8
Topics: CD8-Positive T-Lymphocytes; Humans; Immunity; Lactic Acid; Neoplasms; Pyruvate Carboxylase; Pyruvic | 2022 |
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Topics: Cysteine Endopeptidases; Humans; Mitochondria; Mitochondrial Membranes; Molecular Chaperones; Neopla | 2023 |
The PLOD2/succinate axis regulates the epithelial-mesenchymal plasticity and cancer cell stemness.
Topics: Cell Line, Tumor; Epithelial Cells; Epithelial-Mesenchymal Transition; Humans; Neoplasms; Procollage | 2023 |
HybridSucc: A Hybrid-learning Architecture for General and Species-specific Succinylation Site Prediction.
Topics: Acylation; Algorithms; Amino Acid Sequence; Area Under Curve; Humans; Lysine; Machine Learning; Neop | 2020 |
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors.
Topics: Antineoplastic Agents; Azepines; Benzodiazepines; Citric Acid Cycle; CRISPR-Cas Systems; Dehydroepia | 2017 |
Dual 7-ethyl-10-hydroxycamptothecin conjugated phospholipid prodrug assembled liposomes with in vitro anticancer effects.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Humans; L | 2017 |
Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia.
Topics: Animals; Ascorbic Acid; Cell Hypoxia; Down-Regulation; Humans; Hydrogen Peroxide; Hypoxia-Inducible | 2008 |
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry.
Topics: Citric Acid Cycle; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regul | 2011 |
Targeted cancer therapy with a 2-deoxyglucose-based adriamycin complex.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; De | 2013 |
The influence of succinate and 2, 4-dinitrophenol on the respiratory activity of mouse cancers and normal tissues.
Topics: Animals; Dinitrophenols; Mice; Neoplasms; Nitrophenols; Succinates; Succinic Acid | 1956 |
The influence of succinate and 2, 4-dinitrophenol on the respiratory activity of mouse cancers and normal tissues.
Topics: Animals; Dinitrophenols; Mice; Neoplasms; Nitrophenols; Succinates; Succinic Acid | 1956 |
The influence of succinate and 2, 4-dinitrophenol on the respiratory activity of mouse cancers and normal tissues.
Topics: Animals; Dinitrophenols; Mice; Neoplasms; Nitrophenols; Succinates; Succinic Acid | 1956 |
The influence of succinate and 2, 4-dinitrophenol on the respiratory activity of mouse cancers and normal tissues.
Topics: Animals; Dinitrophenols; Mice; Neoplasms; Nitrophenols; Succinates; Succinic Acid | 1956 |
[Succinyldicholine time as qualified diagnostic; further observations on the clinic aspects of succinic acid dicholinester].
Topics: Digestive System Surgical Procedures; Neoplasms; Stomach Neoplasms; Succinic Acid; Succinylcholine | 1956 |
[Succinyldicholine time as qualified diagnostic; further observations on the clinic aspects of succinic acid dicholinester].
Topics: Digestive System Surgical Procedures; Neoplasms; Stomach Neoplasms; Succinic Acid; Succinylcholine | 1956 |
[Succinyldicholine time as qualified diagnostic; further observations on the clinic aspects of succinic acid dicholinester].
Topics: Digestive System Surgical Procedures; Neoplasms; Stomach Neoplasms; Succinic Acid; Succinylcholine | 1956 |
[Succinyldicholine time as qualified diagnostic; further observations on the clinic aspects of succinic acid dicholinester].
Topics: Digestive System Surgical Procedures; Neoplasms; Stomach Neoplasms; Succinic Acid; Succinylcholine | 1956 |
Metabolic patterns for succinate-2-C14 in tissues of tumor-bearing rats.
Topics: Animals; Encephalomyelitis; Neoplasms; Rats; Succinates; Succinic Acid | 1958 |
The oxidation of succinate by ascites tumor cells.
Topics: Ascites; Biochemical Phenomena; Humans; Metabolism; Neoplasms; Oxidation-Reduction; Succinates; Succ | 1962 |
Succinate stimulation of normal and tumor tissue slice metabolism measured by reduction of tetrazolium chloride.
Topics: Chlorides; Humans; Neoplasms; Succinates; Succinic Acid; Tetrazolium Salts; Tissues | 1951 |
Synthesis and biological evaluation of a paclitaxel immunoconjugate.
Topics: Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Humans; Imm | 2005 |
Correlation between cataract and retinopathy due to lighting in F344 rats used in a long-term carcinogenicity study.
Topics: Animals; Animals, Laboratory; Carcinogens; Cataract; Female; Incidence; Light; Lighting; Male; Neopl | 1992 |