Page last updated: 2024-10-20

succinic acid and MELAS Syndrome

succinic acid has been researched along with MELAS Syndrome in 2 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oguro, H1
Iijima, K1
Takahashi, K1
Nagai, A1
Bokura, H1
Yamaguchi, S1
Kobayashi, S1
Hirata, K1
Akita, Y1
Povalko, N1
Nishioka, J1
Yatsuga, S1
Matsuishi, T1
Koga, Y1

Other Studies

2 other studies available for succinic acid and MELAS Syndrome

ArticleYear
Successful treatment with succinate in a patient with MELAS.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:5

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Electro

2004
Effect of L-arginine on synaptosomal mitochondrial function.
    Brain & development, 2008, Volume: 30, Issue:4

    Topics: Animals; Arginine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; In Vitr

2008