succinic acid has been researched along with Lung Neoplasms in 7 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we evaluated the effect of the recently described α-ketoglutarate dehydrogenase (KGDH) inhibitor, (S)-2-[(2,6-dichlorobenzoyl) amino] succinic acid (AA6), in an orthotopic mouse model of breast cancer 4T1 and in other human breast cancer cell lines." | 3.88 | α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis. ( Atlante, S; Bertinaria, M; Cencioni, C; Dianzani, C; Farsetti, A; Gaetano, C; Giorgis, M; Giraudo, E; Maione, F; Marini, E; Savoia, M; Schnütgen, F; Spallotta, F; Sürün, D; Visintin, A; Zeiher, AM, 2018) |
| "Lysine succinylation is an emerging posttranslational modification that has garnered increased attention recently, but its role in gastric cancer (GC) remains underexplored." | 1.56 | Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer. ( Hu, J; Li, M; Li, X; Li, Y; Ling, T; Mu, X; Pan, J; Shen, J; Su, Z; Wang, C; Wen, H; Wen, J; You, Q; Zhang, C; Zhang, X; Zhao, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, Z | 1 |
| Peng, Y | 1 |
| Gao, J | 1 |
| Zhou, M | 1 |
| Shi, L | 1 |
| Zhao, F | 1 |
| Wang, C | 5 |
| Tian, X | 1 |
| Feng, L | 1 |
| Huo, X | 1 |
| Zhang, B | 1 |
| Liu, M | 1 |
| Fang, D | 1 |
| Ma, X | 1 |
| Wu, JY | 1 |
| Huang, TW | 1 |
| Hsieh, YT | 1 |
| Wang, YF | 1 |
| Yen, CC | 1 |
| Lee, GL | 1 |
| Yeh, CC | 1 |
| Peng, YJ | 1 |
| Kuo, YY | 1 |
| Wen, HT | 1 |
| Lin, HC | 1 |
| Hsiao, CW | 1 |
| Wu, KK | 1 |
| Kung, HJ | 1 |
| Hsu, YJ | 1 |
| Kuo, CC | 1 |
| Li, X | 11 |
| Zhang, C | 1 |
| Zhao, T | 2 |
| Su, Z | 1 |
| Li, M | 2 |
| Hu, J | 3 |
| Wen, J | 1 |
| Shen, J | 4 |
| Pan, J | 1 |
| Mu, X | 1 |
| Ling, T | 1 |
| Li, Y | 6 |
| Wen, H | 1 |
| Zhang, X | 5 |
| You, Q | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
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| Hoplock, LB | 1 |
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| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
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| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
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| Siddique, AB | 1 |
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| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
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| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
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| Zhou, B | 1 |
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| Xing, YL | 1 |
| Chen, MA | 1 |
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| Neradilek, MB | 1 |
| Wu, XT | 1 |
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| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
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| Tarafdari, A | 1 |
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| Keikha, F | 1 |
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| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
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| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
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| Du, H | 1 |
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| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
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| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
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| Dong, X | 1 |
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| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
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| Deng, L | 1 |
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| Rojas, A | 1 |
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| Theobald, A | 1 |
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| Li, J | 7 |
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| Meng, P | 1 |
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| Wang, YS | 1 |
| Zhou, X | 2 |
| Wang, W | 1 |
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| Hou, J | 1 |
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| Pang, D | 1 |
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| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
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| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
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| Yao, H | 1 |
| Wang, X | 5 |
| Lee, DF | 1 |
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| Wu, X | 1 |
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| Rathore, MG | 1 |
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1 review available for succinic acid and Lung Neoplasms
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
1 trial available for succinic acid and Lung Neoplasms
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
6 other studies available for succinic acid and Lung Neoplasms
| Article | Year |
|---|---|
The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis.
Topics: Adenocarcinoma of Lung; Carcinogenesis; Cell Transformation, Neoplastic; Cyclooxygenase 2; HSP90 Hea | 2023 |
Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor.
Topics: A549 Cells; Animals; Cell Line, Tumor; Cell Movement; HT29 Cells; Humans; Hypoxia-Inducible Factor 1 | 2020 |
Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Carnitine O-Palmitoyltransferase; Cell Proliferation; Female; | 2020 |
Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Movement; Endothelial Cells; Enzyme Inhibitors | 2017 |
α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis.
Topics: Animals; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Female | 2018 |
Lipid-like trifunctional block copolymers of ethylene oxide and propylene oxide: effective and cytocompatible modulators of intracellular drug delivery.
Topics: Adenosine Triphosphatases; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfa | 2014 |