Page last updated: 2024-10-20

succinic acid and Lipid Metabolism, Inborn Error

succinic acid has been researched along with Lipid Metabolism, Inborn Error in 3 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roe, CR1
Brunengraber, H1
Ventura, FV1
Ruiter, JP1
Ijlst, L1
Almeida, IT1
Wanders, RJ1
Amendt, BA1
Rhead, WJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 2A/2B Placebo-controlled Randomised Clinical Trial to Test the Ability of Triheptanoin to Protect Primary Airway Epithelial Cells Obtained From Participants With Ataxia-telangiectasia Against Death Induced by Glucose Deprivation[NCT04513002]Phase 230 participants (Actual)Interventional2022-03-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for succinic acid and Lipid Metabolism, Inborn Error

ArticleYear
Anaplerotic treatment of long-chain fat oxidation disorders with triheptanoin: Review of 15 years Experience.
    Molecular genetics and metabolism, 2015, Volume: 116, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Carnitine; Child; Child, Preschool; Citric Acid; Fatty Acid

2015
Inhibition of oxidative phosphorylation by palmitoyl-CoA in digitonin permeabilized fibroblasts: implications for long-chain fatty acid beta-oxidation disorders.
    Biochimica et biophysica acta, 1995, Aug-15, Volume: 1272, Issue:1

    Topics: 2,4-Dinitrophenol; Acyl Coenzyme A; Adenosine Triphosphate; Cell Membrane Permeability; Cells, Cultu

1995
The multiple acyl-coenzyme A dehydrogenation disorders, glutaric aciduria type II and ethylmalonic-adipic aciduria. Mitochondrial fatty acid oxidation, acyl-coenzyme A dehydrogenase, and electron transfer flavoprotein activities in fibroblasts.
    The Journal of clinical investigation, 1986, Volume: 78, Issue:1

    Topics: Acyl Coenzyme A; Acyl-CoA Dehydrogenases; Adipates; Animals; Caprylates; Electron Transport; Electro

1986