succinic acid has been researched along with Koch's Disease in 9 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "tuberculosis have relied on the use of single-gene deletion mutants, raising the possibility that the remaining enzymes could catalyze succinate oxidation in the absence of the other." | 1.72 | Impaired Succinate Oxidation Prevents Growth and Influences Drug Susceptibility in Mycobacterium tuberculosis. ( Adolph, C; Cook, GM; McNeil, MB, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Roca, FJ | 1 |
| Whitworth, LJ | 1 |
| Prag, HA | 1 |
| Murphy, MP | 1 |
| Ramakrishnan, L | 1 |
| Adolph, C | 2 |
| McNeil, MB | 2 |
| Cook, GM | 2 |
| Hards, K | 1 |
| Harold, LK | 1 |
| Cheung, CY | 1 |
| Jinich, A | 1 |
| Rhee, KY | 1 |
| Pham, TV | 1 |
| Murkin, AS | 1 |
| Moynihan, MM | 1 |
| Harris, L | 1 |
| Tyler, PC | 1 |
| Shetty, N | 1 |
| Sacchettini, JC | 1 |
| Huang, HL | 1 |
| Meek, TD | 1 |
| Sibirnaia, RI | 3 |
| Beliakova, OI | 3 |
| Maliuk, VI | 2 |
| Snitinskaia, Os | 2 |
| Kharakter, ZhZ | 1 |
| Sokirko, TA | 1 |
2 reviews available for succinic acid and Koch's Disease
| Article | Year |
|---|---|
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents.
Topics: Antitubercular Agents; Benzoquinones; Citric Acid Cycle; Drug Discovery; Humans; Malates; Mycobacter | 2020 |
[New findings concerning the biochemical mechanisms of the tuberculous process and the correction of biochemical abnormalities using etiopathogenetic preparations].
Topics: Antitubercular Agents; Drug Therapy, Combination; Ethionamide; Fatty Acids; Humans; Isoniazid; Liver | 1984 |
7 other studies available for succinic acid and Koch's Disease
| Article | Year |
|---|---|
Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport.
Topics: Animals; Citric Acid Cycle; Electron Transport; Electron Transport Complex I; Humans; Macrophages; M | 2022 |
Impaired Succinate Oxidation Prevents Growth and Influences Drug Susceptibility in Mycobacterium tuberculosis.
Topics: Carbon; Humans; Mycobacterium tuberculosis; Succinate Dehydrogenase; Succinates; Succinic Acid; Tube | 2022 |
Mechanism-based inactivator of isocitrate lyases 1 and 2 from
Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Glyoxylates; Humans; Isocitr | 2017 |
[Various indicators of the immunological response of the body after inclusion of pathogenetic agents in the chemotherapy of tuberculosis].
Topics: Animals; Antitubercular Agents; Drug Therapy, Combination; Guinea Pigs; Immunity, Cellular; Maleates | 1984 |
[The etiopathogenetic treatment of experimental tuberculosis using preparations with immunomodulating action].
Topics: Adjuvants, Immunologic; Animals; Drug Evaluation, Preclinical; Drug Therapy, Combination; Guinea Pig | 1989 |
[Effect of experimental use of antitubercular preparations and various pathogenetic drugs on the immunological reactions of the body].
Topics: Animals; Antitubercular Agents; Drug Therapy, Combination; Guinea Pigs; In Vitro Techniques; Levamis | 1988 |
[Correction of the toxic effect of isoniazid preparations].
Topics: Animals; Guinea Pigs; Isoniazid; Succinates; Succinic Acid; Tuberculosis | 1987 |