Page last updated: 2024-10-20

succinic acid and Ischemia

succinic acid has been researched along with Ischemia in 28 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" Propofol (2,6-diisopropylphenol) has been proven to attenuate mitochondrial dysfunction and reperfusion injury."7.88Propofol Prevents Oxidative Stress by Decreasing the Ischemic Accumulation of Succinate in Focal Cerebral Ischemia-Reperfusion Injury. ( Gao, D; Jin, W; Liu, S; Qi, S; Yu, W, 2018)
" Propofol (2,6-diisopropylphenol) has been proven to attenuate mitochondrial dysfunction and reperfusion injury."3.88Propofol Prevents Oxidative Stress by Decreasing the Ischemic Accumulation of Succinate in Focal Cerebral Ischemia-Reperfusion Injury. ( Gao, D; Jin, W; Liu, S; Qi, S; Yu, W, 2018)
"Current treatments for acute ischemic stroke aim to reinstate a normal perfusion in the ischemic territory but can also cause significant ischemia-reperfusion (IR) injury."1.91Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke. ( Burger, N; Dannhorn, A; Frezza, C; Goodwin, R; Huang, MM; Krieg, T; Kulaveerasingam, D; Lee, JJ; Mair, R; Mottahedin, A; Murphy, MP; Peruzzotti-Jametti, L; Pluchino, S; Prag, HA; Schmidt, C; Sorby-Adams, A; Yang, M, 2023)
"Upon reoxygenation after anoxia the succinate that had accumulated during anoxia was rapidly oxidized in association with extensive mitochondrial superoxide/hydrogen peroxide production and cell injury, mimicking reperfusion injury."1.72Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury. ( Allen, FM; Bates, GR; Burger, N; Casey, AM; Gruszczyk, AV; Hall, AR; James, AM; Krieg, T; Murphy, MP; Prag, HA; Saeb-Parsy, K, 2022)
"Acute ischemia was followed by an increased in GPR91 expression in the ischemic muscle."1.62Succinate Injection Rescues Vasculature and Improves Functional Recovery Following Acute Peripheral Ischemia in Rodents: A Multimodal Imaging Study. ( Balasse, L; Bouhlel, A; Brige, P; Dignat-George, F; Fernandez, S; Garrigue, P; Guillet, B; Hache, G; Moyon, A; Taïeb, D, 2021)
"In exercise, as well as cancer and ischemia, hypoxia-inducible factor 1 (HIF1) transcriptionally activates hundreds of genes vital for cell homeostasis and angiogenesis."1.35Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. ( Popel, AS; Qutub, AA, 2008)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.14)18.2507
2000's7 (25.00)29.6817
2010's6 (21.43)24.3611
2020's13 (46.43)2.80

Authors

AuthorsStudies
Neimark, MI1
Gruszczyk, AV1
Casey, AM1
James, AM2
Prag, HA3
Burger, N2
Bates, GR1
Hall, AR1
Allen, FM1
Krieg, T4
Saeb-Parsy, K2
Murphy, MP4
Milliken, AS1
Nadtochiy, SM2
Brookes, PS2
Panconesi, R1
Widmer, J1
Carvalho, MF1
Eden, J1
Dondossola, D1
Dutkowski, P1
Schlegel, A1
Kula-Alwar, D1
Bernardi, P1
Di Lisa, F1
Wang, YH1
Yan, ZZ1
Luo, SD1
Hu, JJ1
Wu, M3
Zhao, J2
Liu, WF1
Li, C2
Liu, KX1
Mottahedin, A1
Dannhorn, A1
Mair, R1
Schmidt, C1
Yang, M1
Sorby-Adams, A1
Lee, JJ1
Kulaveerasingam, D1
Huang, MM1
Pluchino, S1
Peruzzotti-Jametti, L1
Goodwin, R1
Frezza, C2
Bongers, KS1
Stringer, KA1
Dickson, RP1
Oh, CJ1
Kim, MJ2
Lee, JM1
Kim, DH1
Kim, IY1
Park, S2
Kim, Y4
Lee, KB1
Lee, SH2
Lim, CW1
Kim, M1
Lee, JY1
Pagire, HS1
Pagire, SH1
Bae, MA1
Chanda, D1
Thoudam, T1
Khang, AR1
Harris, RA1
Ahn, JH1
Jeon, JH1
Lee, IK1
Ozturk, BE1
Nishima, N1
Tanaka, S1
Chinopoulos, C1
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Li, H4
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Ling, J2
Voccio, JP2
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Li, X10
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Zhou, L2
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
He, Y1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Zhao, Y2
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Huang, Y1
Chen, Y3
Chen, L3
Shan, A1
Zhao, H2
Ma, Q1
Wang, J4
Zhang, E1
Zhang, J3
Li, Y5
Xue, F1
Deng, L1
Liu, L2
Yan, Z2
Wang, Y2
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Ren, Y1
Li, J7
Li, P1
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C3
Zhou, X2
Wang, W1
Wang, S2
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J2
Zhang, L2
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X5
Lee, DF1
Shen, J3
Wen, L1
Huang, G2
Xie, X1
Zhao, Q1
Hu, W1
Zhang, Y4
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH2
Lee, SB1
Jung, YJ1
Koh, J1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Yu, K1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W1
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD1
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Chen, W2
Hu, X1
Zhang, F1
Wei, H1
Wang, Z1
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
Ehsanbakhsh, Z1
Validad, MH1
Langroudi, FH1
Esfandiari, H1
Prager, A1
Hassanpour, K1
Kurup, SP1
Mets-Halgrimson, R1
Yoon, H1
Zeid, JL1
Mets, MB1
Rahmani, B1
Araujo-Castillo, RV1
Culquichicón, C1
Solis Condor, R1
Efendi, F1
Sebayang, SK1
Astutik, E1
Hadisuyatmana, S1
Has, EMM1
Kuswanto, H1
Foroutan, T1
Ahmadi, F1
Moayer, F1
Khalvati, S1
Zhang, Q2
Lyu, Y1
Huang, J1
Yu, N1
Wen, Z1
Hou, H1
Zhao, T1
Gupta, A1
Khosla, N1
Govindasamy, V1
Saini, A1
Annapurna, K1
Dhakate, SR1
Akkaya, Ö1
Chandgude, AL1
Dömling, A1
Harnett, J1
Oakes, K1
Carè, J1
Leach, M1
Brown, D1
Cramer, H1
Pinder, TA1
Steel, A1
Anheyer, D1
Cantu, J1
Valle, J1
Flores, K1
Gonzalez, D1
Valdes, C1
Lopez, J1
Padilla, V1
Alcoutlabi, M1
Parsons, J1
Núñez, K1
Hamed, M1
Fort, D1
Bruce, D1
Thevenot, P1
Cohen, A1
Weber, P1
Menezes, AMB1
Gonçalves, H1
Perez-Padilla, R1
Jarvis, D1
de Oliveira, PD1
Wehrmeister, FC1
Mir, S1
Wong, J1
Ryan, CM1
Bellingham, G1
Singh, M2
Waseem, R1
Eckert, DJ1
Chung, F1
Hegde, H1
Shimpi, N1
Panny, A1
Glurich, I1
Christie, P1
Acharya, A1
English, KL1
Downs, M1
Goetchius, E1
Buxton, R1
Ryder, JW1
Ploutz-Snyder, R1
Guilliams, M1
Scott, JM1
Ploutz-Snyder, LL1
Martens, C1
Goplen, FK1
Aasen, T1
Gjestad, R1
Nordfalk, KF1
Nordahl, SHG1
Inoue, T1
Soshi, S1
Kubota, M1
Marumo, K1
Mortensen, NP1
Caffaro, MM1
Patel, PR2
Uddin, MJ1
Aravamudhan, S1
Sumner, SJ1
Fennell, TR1
Gal, RL1
Cohen, NJ1
Kruger, D1
Beck, RW1
Bergenstal, RM1
Calhoun, P1
Cushman, T1
Haban, A1
Hood, K1
Johnson, ML1
McArthur, T1
Olson, BA1
Weinstock, RS1
Oser, SM1
Oser, TK1
Bugielski, B1
Strayer, H1
Aleppo, G1
Maruyama, H1
Hirayama, K1
Yamashita, M1
Ohgi, K1
Tsujimoto, R1
Takayasu, M1
Shimohata, H1
Kobayashi, M1
Buscagan, TM1
Rees, DC1
Jaborek, JR1
Zerby, HN1
Wick, MP1
Fluharty, FL1
Moeller, SJ1
Razavi, P1
Dickler, MN1
Shah, PD1
Toy, W1
Brown, DN1
Won, HH1
Li, BT1
Shen, R1
Vasan, N1
Modi, S1
Jhaveri, K1
Caravella, BA1
Patil, S1
Selenica, P1
Zamora, S1
Cowan, AM1
Comen, E1
Singh, A1
Covey, A1
Berger, MF1
Hudis, CA1
Norton, L1
Nagy, RJ1
Odegaard, JI1
Lanman, RB1
Solit, DB1
Robson, ME1
Lacouture, ME1
Brogi, E1
Reis-Filho, JS1
Moynahan, ME1
Scaltriti, M1
Chandarlapaty, S1
Papouskova, K1
Moravcova, M1
Masrati, G1
Ben-Tal, N1
Sychrova, H1
Zimmermannova, O1
Fang, J1
Fan, Y1
Luo, T2
Su, H1
Tsetseris, L1
Anthopoulos, TD1
Liu, SF1
Zhao, K1
Sacan, O1
Turkyilmaz, IB1
Bayrak, BB1
Mutlu, O1
Akev, N1
Yanardag, R1
Gruber, S1
Kamnoedboon, P1
Özcan, M1
Srinivasan, M1
Jo, YH1
Oh, HK1
Jeong, SY1
Lee, BG1
Zheng, J1
Guan, H1
Li, D2
Tan, H1
Maji, TK1
J R, A1
Mukherjee, S1
Alexander, R1
Mondal, A1
Das, S1
Sharma, RK1
Chakraborty, NK1
Dasgupta, K1
Sharma, AMR1
Hawaldar, R1
Pandey, M1
Naik, A1
Majumdar, K1
Pal, SK1
Adarsh, KV1
Ray, SK1
Karmakar, D1
Ma, Y2
Gao, W1
Ma, S1
Lin, W1
Zhou, T1
Wu, T1
Wu, Q1
Ye, C1
He, X1
Jiang, F1
Yuan, D1
Chen, Q2
Hong, M1
Chen, K1
Hussain, M1
Razi, SS1
Yildiz, EA1
Yaglioglu, HG1
Donato, MD1
Jiang, J1
Jamil, MI1
Zhan, X1
Chen, F1
Cheng, D1
Wu, CT1
Utsunomiya, T1
Ichii, T1
Fujinami, S1
Nakajima, K1
Sanchez, DM1
Raucci, U1
Ferreras, KN1
Martínez, TJ1
Mordi, NA1
Mordi, IR1
Singh, JS1
McCrimmon, RJ1
Struthers, AD1
Lang, CC1
Wang, XW1
Yuan, LJ1
Yang, Y1
Chen, WF1
Luo, R1
Yang, K1
Amarasiri, SS1
Attanayake, AP1
Arawwawala, LDAM1
Jayatilaka, KAPW1
Mudduwa, LKB1
Ogunsuyi, O2
Akanni, O1
Alabi, O1
Alimba, C1
Adaramoye, O1
Cambier, S1
Eswara, S1
Gutleb, AC1
Bakare, A1
Gu, Z1
Cong, J1
Pellegrini, M1
Palmieri, S1
Ricci, A1
Serio, A1
Paparella, A1
Lo Sterzo, C1
Jadeja, SD1
Vaishnav, J1
Mansuri, MS1
Shah, C1
Mayatra, JM1
Shah, A1
Begum, R1
Song, H2
Lian, Y1
Wan, T1
Schultz-Lebahn, A1
Skipper, MT1
Hvas, AM1
Larsen, OH1
Hijazi, Z1
Granger, CB1
Hohnloser, SH1
Westerbergh, J1
Lindbäck, J1
Alexander, JH1
Keltai, M1
Parkhomenko, A1
López-Sendón, JL1
Lopes, RD1
Siegbahn, A1
Wallentin, L1
El-Tarabany, MS1
Saleh, AA1
El-Araby, IE1
El-Magd, MA1
van Ginkel, MPH1
Schijven, MP1
van Grevenstein, WMU1
Schreuder, HWR1
Pereira, EDM1
da Silva, J1
Carvalho, PDS1
Grivicich, I1
Picada, JN1
Salgado Júnior, IB1
Vasques, GJ1
Pereira, MADS1
Reginatto, FH1
Ferraz, ABF1
Vasilenko, EA1
Gorshkova, EN1
Astrakhantseva, IV1
Drutskaya, MS1
Tillib, SV1
Nedospasov, SA1
Mokhonov, VV1
Nam, YW1
Cui, M1
Orfali, R1
Viegas, A1
Nguyen, M1
Mohammed, EHM1
Zoghebi, KA1
Rahighi, S1
Parang, K1
Patterson, KC1
Kahanovitch, U1
Gonçalves, CM1
Hablitz, JJ1
Staruschenko, A1
Mulkey, DK1
Olsen, ML1
Gu, L1
Cao, X1
Mukhtar, A1
Wu, K1
Zhang, YY1
Zhu, Y1
Lu, DZ1
Dong, W1
Bi, WJ1
Feng, XJ1
Wen, LM1
Sun, H1
Qi, MC1
Chang, CC1
Dinh, TK1
Lee, YA1
Wang, FN1
Sung, YC1
Yu, PL1
Chiu, SC1
Shih, YC1
Wu, CY1
Huang, YD1
Lu, TT1
Wan, D1
Sakizadeh, J1
Cline, JP1
Snyder, MA1
Kiely, CJ1
McIntosh, S1
Jiang, X1
Cao, JW1
Zhao, CK1
Yang, R1
Zhang, QY1
Chen, KJ2
Liu, H1
He, Z1
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Du, X1
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Sloane, BF1
Lum, LG1
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Luengo, A1
Marzo, I1
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Daubit, IM1
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Gimeno, MC1
Tonchev, I1
Heberman, D1
Peretz, A1
Medvedovsky, AT1
Gotsman, I1
Rashi, Y1
Poles, L1
Goland, S1
Perlman, GY1
Danenberg, HD1
Beeri, R1
Shuvy, M1
Fu, Q1
Yang, D1
Sarapulova, A1
Pang, Q1
Meng, Y1
Wei, L1
Ehrenberg, H1
Kim, CC1
Jeong, SH1
Oh, KH1
Nam, KT1
Sun, JY1
Ning, J1
Duan, Z1
Kershaw, SV1
Rogach, AL1
Gao, Z1
Wang, T1
Li, Q1
Cao, T1
Guo, L1
Fu, Y1
Seeger, ZL1
Izgorodina, EI1
Hue, S1
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Mekontso-Dessap, A1
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Gao, SS1
Duangthip, D1
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Chu, CH1
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Rosenheck, RA1
Miyake, T1
Kimoto, E1
Luo, L1
Mathialagan, S1
Horlbogen, LM1
Ramanathan, R1
Wood, LS1
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Le, VH1
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Rodrigues, AD1
Muto, C1
Furihata, K1
Sugiyama, Y1
Kusuhara, H1
Gong, Q1
Song, W1
Sun, B1
Cao, P1
Gu, S1
Sun, X1
Zhou, G1
Toma, C1
Khandhar, S1
Zalewski, AM1
D'Auria, SJ1
Tu, TM1
Jaber, WA1
Cho, J2
Suwandaratne, NS1
Razek, S1
Choi, YH1
Piper, LFJ1
Watson, DF1
Banerjee, S1
Xie, S1
Lindsay, AP1
Bates, FS1
Lodge, TP1
Hao, Y1
Chapovetsky, A1
Liu, JJ1
Welborn, M1
Luna, JM1
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Miller Iii, TF1
Marinescu, SC1
Lopez, SA1
Compter, I1
Eekers, DBP1
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Wesseling, P1
Postma, AA1
De Ruysscher, D1
Lambin, P1
Qiang, L1
Yang, S1
Cui, YH1
He, YY1
Kumar, SK1
Jacobus, SJ1
Cohen, AD1
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Singh, AK1
Parker, TL1
Menter, A1
Parsons, B1
Kumar, P1
Kapoor, P1
Rosenberg, A1
Zonder, JA1
Faber, E1
Lonial, S1
Anderson, KC1
Richardson, PG1
Orlowski, RZ1
Wagner, LI1
Rajkumar, SV1
Li, G1
Hou, G1
Cui, J1
Xie, H1
Sun, Z1
Fang, Z1
Dunstand-Guzmán, E1
Hallal-Calleros, C1
Hernández-Velázquez, VM1
Canales-Vargas, EJ1
Domínguez-Roldan, R1
Pedernera, M1
Peña-Chora, G1
Flores-Pérez, I1
Han, C1
White, K1
Park, HJ1
Ding, D1
Boyd, K1
Rothenberger, C1
Bose, U1
Carmichael, P1
Linser, PJ1
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Salvi, R1
Someya, S1
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Dharuman, V1
Feng, J2
Qian, Y1
Cheng, Q1
Ma, H1
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Pierro, A1

Reviews

4 reviews available for succinic acid and Ischemia

ArticleYear
[Ischemia-reperfusion syndrome].
    Khirurgiia, 2021, Issue:9

    Topics: Humans; Ischemia; Reperfusion; Reperfusion Injury; Succinic Acid

2021
Mitochondria and ischemia reperfusion injury.
    Current opinion in organ transplantation, 2022, 10-01, Volume: 27, Issue:5

    Topics: Humans; Inflammation; Ischemia; Mitochondria; Reperfusion Injury; Succinic Acid

2022
Succinate in ischemia: Where does it come from?
    The international journal of biochemistry & cell biology, 2019, Volume: 115

    Topics: Animals; Humans; Ischemia; Mitochondria; Succinate Dehydrogenase; Succinic Acid

2019
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021

Trials

1 trial available for succinic acid and Ischemia

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021

Other Studies

24 other studies available for succinic acid and Ischemia

ArticleYear
Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury.
    Redox biology, 2022, Volume: 54

    Topics: Animals; Disease Models, Animal; Energy Metabolism; Hypoxia; Ischemia; Lactates; Mice; Myocytes, Car

2022
Inhibiting Succinate Release Worsens Cardiac Reperfusion Injury by Enhancing Mitochondrial Reactive Oxygen Species Generation.
    Journal of the American Heart Association, 2022, 07-05, Volume: 11, Issue:13

    Topics: Animals; Ischemia; Mice; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondri

2022
Cyclophilin D knockout mice do not accumulate succinate during cardiac ischemia.
    Journal of molecular and cellular cardiology, 2022, Volume: 173

    Topics: Animals; Cyclophilins; Ischemia; Mice; Mice, Knockout; Mitochondrial Membrane Transport Proteins; Pe

2022
Gut microbiota-derived succinate aggravates acute lung injury after intestinal ischaemia/reperfusion in mice.
    The European respiratory journal, 2023, Volume: 61, Issue:2

    Topics: Acute Lung Injury; Animals; Gastrointestinal Microbiome; Ischemia; Mice; Mice, Inbred C57BL; Phospha

2023
Targeting succinate metabolism to decrease brain injury upon mechanical thrombectomy treatment of ischemic stroke.
    Redox biology, 2023, Volume: 59

    Topics: Animals; Brain Injuries; Brain Ischemia; Humans; Ischemia; Ischemic Stroke; Mice; Reperfusion Injury

2023
The gut microbiome in ARDS: from the "whether" and "what" to the "how".
    The European respiratory journal, 2023, Volume: 61, Issue:2

    Topics: Acute Lung Injury; Animals; Gastrointestinal Microbiome; Ischemia; Mice; Respiratory Distress Syndro

2023
Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion.
    Kidney international, 2023, Volume: 104, Issue:4

    Topics: Animals; Ischemia; Kidney; Mice; Mice, Knockout; Mitochondria; Reactive Oxygen Species; Reperfusion;

2023
Understanding Ischemic Retinopathies: The Role of Succinate and Its Receptor in Retinal Pigment Epithelium.
    Advances in experimental medicine and biology, 2023, Volume: 1415

    Topics: Humans; Infant, Newborn; Ischemia; Retina; Retinal Diseases; Retinal Pigment Epithelium; Retinal Ves

2023
Suppressing succinate accumulation during ischemia protects the kidney from IRI.
    Kidney international, 2023, Volume: 104, Issue:4

    Topics: Acute Kidney Injury; Humans; Ischemia; Kidney; Succinates; Succinic Acid

2023
Succinate Injection Rescues Vasculature and Improves Functional Recovery Following Acute Peripheral Ischemia in Rodents: A Multimodal Imaging Study.
    Cells, 2021, 04-02, Volume: 10, Issue:4

    Topics: Acute Disease; Animals; Endothelial Cells; Female; Gallium Radioisotopes; Hindlimb; Injections; Isch

2021
Propofol Prevents Oxidative Stress by Decreasing the Ischemic Accumulation of Succinate in Focal Cerebral Ischemia-Reperfusion Injury.
    Neurochemical research, 2018, Volume: 43, Issue:2

    Topics: Animals; Brain Ischemia; Ischemia; Male; Membrane Potential, Mitochondrial; Mitochondria; Neuroprote

2018
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
    Nature, 2014, Nov-20, Volume: 515, Issue:7527

    Topics: Adenosine Monophosphate; Animals; Aspartic Acid; Citric Acid Cycle; Disease Models, Animal; Electron

2014
Biochemistry: succinate strikes.
    Nature, 2014, Nov-20, Volume: 515, Issue:7527

    Topics: Animals; Ischemia; Male; Mitochondria; Reactive Oxygen Species; Reperfusion Injury; Succinic Acid

2014
Mitochondrial metabolomics unravel the primordial trigger of ischemia/reperfusion injury.
    Gastroenterology, 2015, Volume: 148, Issue:5

    Topics: Animals; Ischemia; Male; Mitochondria; Reactive Oxygen Species; Reperfusion Injury; Succinic Acid

2015
Succinate: A Promising Therapeutic Target for Reperfusion Injury.
    Neurosurgery, 2015, Volume: 77, Issue:6

    Topics: Animals; Ischemia; Male; Mitochondria; Reactive Oxygen Species; Reperfusion Injury; Succinic Acid

2015
Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia.
    Molecular and cellular biology, 2008, Volume: 28, Issue:16

    Topics: Animals; Ascorbic Acid; Cell Hypoxia; Down-Regulation; Humans; Hydrogen Peroxide; Hypoxia-Inducible

2008
The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis.
    Nature medicine, 2008, Volume: 14, Issue:10

    Topics: Animals; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Rats; Rats, Sprague-Dawley; Receptors,

2008
Contralateral leg as a control during skeletal muscle ischemia-reperfusion.
    The Journal of surgical research, 2009, Volume: 155, Issue:1

    Topics: Animals; Ascorbic Acid; Cell Respiration; Electron Transport Chain Complex Proteins; Glutamic Acid;

2009
[Supply and demand: the influence of energy metabolism on angiogenesis].
    Medecine sciences : M/S, 2009, Volume: 25, Issue:4

    Topics: Animals; Diabetic Retinopathy; Energy Metabolism; Humans; Hypoxia; Infant, Newborn; Injections; Isch

2009
Production of reactive oxygen species by mitochondria: central role of complex III.
    The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38

    Topics: Animals; Antioxidants; Binding Sites; Catalase; Electron Transport; Electron Transport Complex III;

2003
Succinate is a paracrine signal for liver damage.
    Journal of hepatology, 2007, Volume: 47, Issue:2

    Topics: Animals; Fluorescent Antibody Technique; In Vitro Techniques; Infusions, Intravenous; Ischemia; Live

2007
Effect of renal ischaemia on organic compound transport in rabbit kidney proximal tubule.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:2

    Topics: Alkaline Phosphatase; Animals; Biological Transport, Active; Cell Membrane; Female; Glomerular Filtr

1995
Enterocyte viability and mitochondrial function after graded intestinal ischemia and reperfusion in rats.
    Molecular and cellular biochemistry, 1997, Volume: 167, Issue:1-2

    Topics: Animals; Formazans; Intestinal Mucosa; Intestine, Small; Ischemia; Mitochondria; Rats; Reperfusion;

1997
Intestinal metabolism after ischemia-reperfusion.
    Journal of pediatric surgery, 2000, Volume: 35, Issue:5

    Topics: Amino Acids; Analysis of Variance; Animals; Disease Models, Animal; Glucose; Intestine, Small; Ische

2000