Page last updated: 2024-10-20

succinic acid and Inflammation

succinic acid has been researched along with Inflammation in 48 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"We studied the effects of original Russian derivatives of 3-hydroxypyridine and succinic acid (emoxipine, reamberin and mexidol) on the time course of endometrial leukocyte infiltration, blood levels of inflammatory cytokines (IL-1β and TNF-α), and indicators of affective status in women with exacerbation of the chronic inflammation of the uterus and adnexa."9.19Effects of 3-hydroxypyridine derivatives and succinic acid on endometrial leukocyte infiltration, cytokinemia and related affective symptoms during exacerbation of the chronic inflammation of the uterus and adnexa. ( Pravdin, EV; Uzlova, TV; Volchegorskii, IA, 2014)
"Short-term, prospective placebo-controlled simple blind randomized study of the effects of 3-oxypyridine and succinic acid derivatives (emoxipin, reamberin, mexidol) on the affective status of females with recrudescence of the inflammatory diseases of uterus and its appendages (IDUA) in comparison to changes of systemic inflammatory response (SIR) markers level in the blood has been conducted."9.16[Effect of 3-oxypyridine and succinic acid derivatives on affective status in recrudescence of inflammatory diseases of uterus and its appendages]. ( Pravdin, EV; Uzlova, TV; Volchegorskiĭ, IA, 2012)
"We studied the effects of original Russian derivatives of 3-hydroxypyridine and succinic acid (emoxipine, reamberin and mexidol) on the time course of endometrial leukocyte infiltration, blood levels of inflammatory cytokines (IL-1β and TNF-α), and indicators of affective status in women with exacerbation of the chronic inflammation of the uterus and adnexa."5.19Effects of 3-hydroxypyridine derivatives and succinic acid on endometrial leukocyte infiltration, cytokinemia and related affective symptoms during exacerbation of the chronic inflammation of the uterus and adnexa. ( Pravdin, EV; Uzlova, TV; Volchegorskii, IA, 2014)
"Short-term, prospective placebo-controlled simple blind randomized study of the effects of 3-oxypyridine and succinic acid derivatives (emoxipin, reamberin, mexidol) on the affective status of females with recrudescence of the inflammatory diseases of uterus and its appendages (IDUA) in comparison to changes of systemic inflammatory response (SIR) markers level in the blood has been conducted."5.16[Effect of 3-oxypyridine and succinic acid derivatives on affective status in recrudescence of inflammatory diseases of uterus and its appendages]. ( Pravdin, EV; Uzlova, TV; Volchegorskiĭ, IA, 2012)
"Intravitreal/periocular injection of triamcinolone acetonide (TA) suspension is a common uveitis treatment, but it displays a high risk for serious side effects (e."3.88Glycosylation-enhanced biocompatibility of the supramolecular hydrogel of an anti-inflammatory drug for topical suppression of inflammation. ( Lei, L; Li, X; Song, Q; Xiong, T; Zhang, R; Zhou, Y, 2018)
"There is an increased risk of colon cancer associated with inflammatory bowel disease (IBD)."1.91Refined fiber inulin promotes inflammation-associated colon tumorigenesis by modulating microbial succinate production. ( Castro, R; Hao, F; Neupane, R; Patterson, AD; Paudel, D; Prabhu, KS; Singh, V; Tian, S; Tiwari, AK, 2023)
"Hypoxia from lung injury is mainly regulated by hypoxia-inducible factor 1α (HIF-1α)."1.91Role of succinate in airway epithelial cell regulation following traumatic lung injury. ( Aktay, S; Arnipalli, MS; Pennathur, S; Raghavendran, K; Sathyarajan, DT; Solanki, S; Suresh, MV; Yalamanchili, G, 2023)
"The pathogenesis of Crohn's disease-associated fibrostenosis and fistulas imply the epithelial-to-mesenchymal transition (EMT) process."1.56Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development. ( Alós, R; Barrachina, MD; Bauset, C; Calatayud, S; Coll, S; Cosín-Roger, J; Esplugues, JV; Gisbert-Ferrándiz, L; Mamie, C; Navarro, F; Ortiz-Masiá, D; Scharl, M, 2020)
"Lactic acid (LA) is a major organic acid metabolite produced by vaginal lactobacilli that elicits anti-inflammatory effects from cervicovaginal epithelial cells and is dramatically depleted during BV."1.51Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota. ( Delgado-Diaz, DJ; Gugasyan, R; Hayward, JA; Hearps, AC; Tachedjian, G; Tyssen, D, 2019)
"Itaconic acid is an important metabolite produced by macrophages after stimulation with LPS."1.46Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly. ( Burant, CF; ElAzzouny, M; Evans, CR; Gallagher, KA; Martin, BR; Olson, LL; Tanga, MJ; Tom, CT, 2017)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (4.17)29.6817
2010's24 (50.00)24.3611
2020's22 (45.83)2.80

Authors

AuthorsStudies
Ruan, Y1
Ling, J3
Ye, F1
Cheng, N1
Wu, F1
Tang, Z1
Cheng, X1
Liu, H2
Panconesi, R1
Widmer, J1
Carvalho, MF1
Eden, J1
Dondossola, D1
Dutkowski, P1
Schlegel, A1
Huber-Ruano, I1
Calvo, E2
Mayneris-Perxachs, J1
Rodríguez-Peña, MM1
Ceperuelo-Mallafré, V2
Cedó, L1
Núñez-Roa, C2
Miro-Blanch, J1
Arnoriaga-Rodríguez, M1
Balvay, A1
Maudet, C1
García-Roves, P1
Yanes, O1
Rabot, S1
Grimaud, GM1
De Prisco, A1
Amoruso, A1
Fernández-Real, JM1
Vendrell, J2
Fernández-Veledo, S2
Fedotcheva, N1
Beloborodova, N1
Guo, Y1
Xu, F1
Thomas, SC1
Zhang, Y9
Paul, B1
Sakilam, S1
Chae, S1
Li, P2
Almeter, C1
Kamer, AR1
Arora, P1
Graves, DT1
Saxena, D1
Li, X15
Sell, EA1
Tan, LH1
Lin, C1
Bosso, JV1
Palmer, JN1
Adappa, ND1
Lee, RJ1
Kohanski, MA1
Reed, DR1
Cohen, NA1
Wang, S3
Liu, B2
Huang, J2
He, H1
Zhou, L3
He, Y2
Yan, J1
Tao, A1
Cao, Z1
Mu, S1
Wang, M1
Zou, G1
Yuan, X1
Huang, Y2
Yu, S1
Zhang, J4
Zhang, C1
Coutry, N1
Nguyen, J1
Soualhi, S1
Gerbe, F1
Meslier, V1
Dardalhon, V1
Almeida, M1
Quinquis, B1
Thirion, F1
Herbert, F1
Gasmi, I1
Lamrani, A1
Giordano, A1
Cesses, P1
Garnier, L1
Thirard, S1
Greuet, D1
Cazevieille, C1
Bernex, F1
Bressuire, C1
Winton, D1
Matsumoto, I1
Blottière, HM1
Taylor, N1
Jay, P1
Mateska, I1
Witt, A1
Hagag, E1
Sinha, A1
Yilmaz, C1
Thanou, E1
Sun, N1
Kolliniati, O1
Patschin, M1
Abdelmegeed, H1
Henneicke, H1
Kanczkowski, W1
Wielockx, B1
Tsatsanis, C1
Dahl, A1
Walch, AK1
Li, KW1
Peitzsch, M1
Chavakis, T1
Alexaki, VI1
Ben-Arosh, H1
Avraham, R1
Huang, G3
Ren, Y2
Zhang, R2
Zhu, W2
Yu, K3
Tian, S1
Paudel, D1
Hao, F1
Neupane, R1
Castro, R1
Patterson, AD1
Tiwari, AK1
Prabhu, KS1
Singh, V1
Suresh, MV1
Aktay, S1
Yalamanchili, G1
Solanki, S1
Sathyarajan, DT1
Arnipalli, MS1
Pennathur, S1
Raghavendran, K1
Mao, M1
Su, W1
Shi, J1
Zhao, Y3
Yan, F1
Lei, L2
Li, H5
Delgado-Diaz, DJ1
Tyssen, D1
Hayward, JA1
Gugasyan, R1
Hearps, AC1
Tachedjian, G1
Zasłona, Z1
O'Neill, LAJ1
Ortiz-Masiá, D2
Gisbert-Ferrándiz, L2
Bauset, C1
Coll, S1
Mamie, C1
Scharl, M1
Esplugues, JV2
Alós, R2
Navarro, F2
Cosín-Roger, J2
Barrachina, MD2
Calatayud, S2
Nguépy Keubo, FR1
Mboua, PC1
Djifack Tadongfack, T1
Fokouong Tchoffo, E1
Tasson Tatang, C1
Ide Zeuna, J1
Noupoue, EM1
Tsoplifack, CB1
Folefack, GO1
Kettani, M1
Bandelier, P1
Huo, J1
Yu, D1
Arulsamy, N1
AlAbbad, S1
Sardot, T1
Lekashvili, O1
Decato, D1
Lelj, F1
Alexander Ross, JB1
Rosenberg, E1
Nazir, H1
Muthuswamy, N1
Louis, C1
Jose, S1
Prakash, J1
Buan, MEM1
Flox, C1
Chavan, S1
Shi, X1
Kauranen, P1
Kallio, T1
Maia, G1
Tammeveski, K1
Lymperopoulos, N1
Carcadea, E1
Veziroglu, E1
Iranzo, A1
M Kannan, A1
Arunamata, A1
Tacy, TA1
Kache, S1
Mainwaring, RD1
Ma, M1
Maeda, K1
Punn, R1
Noguchi, S1
Hahn, S3
Iwasa, Y3
Voccio, JP2
Kim, Y3
Song, J3
Bascuñán, J2
Chu, Y1
Tomita, M1
Cazorla, M1
Herrera, E1
Palomeque, E1
Saud, N1
Hoplock, LB1
Lobchuk, MM1
Lemoine, J1
Henson, MA1
Unsihuay, D1
Qiu, J1
Swaroop, S1
Nagornov, KO1
Kozhinov, AN1
Tsybin, YO1
Kuang, S1
Laskin, J1
Zin, NNINM1
Mohamad, MN1
Roslan, K1
Abdul Wafi, S1
Abdul Moin, NI1
Alias, A1
Zakaria, Y1
Abu-Bakar, N1
Naveed, A1
Jilani, K1
Siddique, AB1
Akbar, M1
Riaz, M1
Mushtaq, Z1
Sikandar, M1
Ilyas, S1
Bibi, I1
Asghar, A1
Rasool, G1
Irfan, M1
Li, XY1
Zhao, S1
Fan, XH1
Chen, KP1
Hua, W1
Liu, ZM1
Xue, XD1
Zhou, B1
Zhang, S2
Xing, YL1
Chen, MA1
Sun, Y1
Neradilek, MB1
Wu, XT1
Zhang, D2
Huang, W1
Cui, Y1
Yang, QQ1
Li, HW1
Zhao, XQ1
Hossein Rashidi, B1
Tarafdari, A1
Ghazimirsaeed, ST1
Shahrokh Tehraninezhad, E1
Keikha, F1
Eslami, B1
Ghazimirsaeed, SM1
Jafarabadi, M1
Silvani, Y1
Lovita, AND1
Maharani, A1
Wiyasa, IWA1
Sujuti, H1
Ratnawati, R1
Raras, TYM1
Lemin, AS1
Rahman, MM1
Pangarah, CA1
Kiyu, A1
Zeng, C2
Du, H1
Lin, D1
Jalan, D1
Rubagumya, F1
Hopman, WM1
Vanderpuye, V1
Lopes, G1
Seruga, B1
Booth, CM1
Berry, S1
Hammad, N1
Sajo, EA1
Okunade, KS1
Olorunfemi, G1
Rabiu, KA1
Anorlu, RI1
Xu, C2
Xiang, Y1
Xu, X1
Dong, X1
Tang, S1
Gao, XC1
Wei, CH1
Zhang, RG1
Cai, Q1
Tong, F1
Dong, JH1
Wu, G1
Dong, XR1
Tang, X1
Tao, F1
Xiang, W1
Jin, L1
Tao, H1
Lei, Y1
Gan, H1
Chen, Y3
Chen, L3
Shan, A1
Zhao, H2
Wu, M2
Ma, Q2
Wang, J4
Zhang, E1
Li, Y5
Xue, F1
Deng, L1
Liu, L2
Yan, Z2
Wang, Y2
Meng, J1
Chen, G2
Anastassiadou, M1
Bernasconi, G1
Brancato, A1
Carrasco Cabrera, L1
Greco, L1
Jarrah, S1
Kazocina, A1
Leuschner, R1
Magrans, JO1
Miron, I1
Nave, S1
Pedersen, R1
Reich, H1
Rojas, A1
Sacchi, A1
Santos, M1
Theobald, A1
Vagenende, B1
Verani, A1
Du, L1
Liu, X1
Li, J7
Jiao, Q1
Meng, P1
Wang, F2
Wang, YS1
Wang, C3
Zhou, X2
Wang, W1
Hou, J1
Zhang, A1
Lv, B1
Gao, C1
Pang, D1
Lu, K1
Ahmad, NH1
Wang, L1
Zhu, J2
Zhang, L2
Zhuang, T1
Tu, J1
Zhao, Z1
Qu, Y1
Yao, H1
Wang, X5
Lee, DF1
Shen, J3
Wen, L1
Xie, X1
Zhao, Q1
Hu, W1
Wu, X1
Lu, J2
Li, M1
Li, W2
Wu, W1
Du, F1
Ji, H1
Yang, X2
Xu, Z1
Wan, L1
Wen, Q1
Cho, CH1
Zou, C1
Xiao, Z1
Liao, J1
Su, X1
Bi, Z1
Su, Q1
Huang, H1
Wei, Y2
Gao, Y2
Na, KJ1
Choi, H1
Oh, HR1
Kim, YH1
Lee, SB1
Jung, YJ1
Koh, J1
Park, S1
Lee, HJ1
Jeon, YK1
Chung, DH1
Paeng, JC1
Park, IK1
Kang, CH1
Cheon, GJ1
Kang, KW1
Lee, DS1
Kim, YT1
Pajuelo-Lozano, N1
Alcalá, S1
Sainz, B1
Perona, R1
Sanchez-Perez, I1
Logotheti, S1
Marquardt, S1
Gupta, SK1
Richter, C1
Edelhäuser, BAH1
Engelmann, D1
Brenmoehl, J1
Söhnchen, C1
Murr, N1
Alpers, M1
Singh, KP1
Wolkenhauer, O1
Heckl, D1
Spitschak, A1
Pützer, BM1
Liao, Y1
Cheng, J1
Kong, X1
Li, S1
Zhang, M4
Zhang, H1
Yang, T2
Dong, Y1
Xu, Y1
Yuan, Z1
Cao, J1
Zheng, Y1
Luo, Z1
Mei, Z1
Yao, Y1
Liu, Z2
Liang, C1
Yang, H1
Song, Y1
Zhu, C1
Huang, Z1
Qian, J1
Ge, J1
Hu, J2
Wang, H2
Liu, Y4
Mi, Y1
Kong, H1
Xi, D1
Yan, W2
Luo, X1
Ning, Q1
Chang, X2
Zhang, T2
Wang, Q2
Rathore, MG1
Reddy, K1
Chen, H1
Shin, SH1
Ma, WY1
Bode, AM1
Dong, Z1
Mu, W1
Liu, C3
Gao, F1
Qi, Y1
Lu, H1
Zhang, X4
Cai, X1
Ji, RY1
Hou, Y3
Tian, J2
Shi, Y1
Ying, S1
Tan, M1
Feng, G1
Kuang, Y1
Chen, D1
Wu, D3
Zhu, ZQ1
Tang, HX1
Shi, ZE1
Kang, J1
Liu, Q1
Qi, J2
Mu, J1
Cong, Z1
Chen, S2
Fu, D1
Li, Z2
Celestrin, CP1
Rocha, GZ1
Stein, AM1
Guadagnini, D1
Tadelle, RM1
Saad, MJA1
Oliveira, AG1
Bianconi, V1
Bronzo, P1
Banach, M1
Sahebkar, A1
Mannarino, MR1
Pirro, M1
Patsourakos, NG1
Kouvari, M1
Kotidis, A1
Kalantzi, KI1
Tsoumani, ME1
Anastasiadis, F1
Andronikos, P1
Aslanidou, T1
Efraimidis, P1
Georgiopoulos, A1
Gerakiou, K1
Grigoriadou-Skouta, E1
Grigoropoulos, P1
Hatzopoulos, D1
Kartalis, A1
Lyras, A1
Markatos, G1
Mikrogeorgiou, A1
Myroforou, I1
Orkopoulos, A1
Pavlidis, P1
Petras, C1
Riga, M1
Skouloudi, M1
Smyrnioudis, N1
Thomaidis, K1
Tsikouri, GE1
Tsikouris, EI1
Zisimos, K1
Vavoulis, P1
Vitali, MG1
Vitsas, G1
Vogiatzidis, C1
Chantanis, S1
Fousas, S1
Panagiotakos, DB1
Tselepis, AD1
Jungen, C1
Alken, FA1
Eickholt, C1
Scherschel, K1
Kuklik, P1
Klatt, N1
Schwarzl, J1
Moser, J1
Jularic, M1
Akbulak, RO1
Schaeffer, B1
Willems, S1
Meyer, C1
Nowak, JK1
Szczepanik, M1
Trypuć, M1
Pogorzelski, A1
Bobkowski, W1
Grytczuk, M1
Minarowska, A1
Wójciak, R1
Walkowiak, J1
Lu, Y1
Xi, J1
Li, C1
Chen, W2
Hu, X1
Zhang, F1
Wei, H1
Wang, Z2
Gurzu, S1
Jung, I1
Sugimura, H2
Stefan-van Staden, RI1
Yamada, H1
Natsume, H1
Iwashita, Y1
Szodorai, R1
Szederjesi, J1
Yari, D1
Ehsanbakhsh, Z1
Validad, MH1
Langroudi, FH1
Esfandiari, H1
Prager, A1
Hassanpour, K1
Kurup, SP1
Mets-Halgrimson, R1
Yoon, H1
Zeid, JL1
Mets, MB1
Rahmani, B1
Araujo-Castillo, RV1
Culquichicón, C1
Solis Condor, R1
Efendi, F1
Sebayang, SK1
Astutik, E1
Hadisuyatmana, S1
Has, EMM1
Kuswanto, H1
Foroutan, T1
Ahmadi, F1
Moayer, F1
Khalvati, S1
Zhang, Q2
Lyu, Y1
Yu, N1
Wen, Z1
Hou, H1
Zhao, T1
Gupta, A1
Khosla, N1
Govindasamy, V1
Saini, A1
Annapurna, K1
Dhakate, SR1
Akkaya, Ö1
Chandgude, AL1
Dömling, A1
Harnett, J1
Oakes, K1
Carè, J1
Leach, M1
Brown, D1
Cramer, H1
Pinder, TA1
Steel, A1
Anheyer, D1
Cantu, J1
Valle, J1
Flores, K1
Gonzalez, D1
Valdes, C1
Lopez, J1
Padilla, V1
Alcoutlabi, M1
Parsons, J1
Núñez, K1
Hamed, M1
Fort, D1
Bruce, D1
Thevenot, P1
Cohen, A1
Weber, P1
Menezes, AMB1
Gonçalves, H1
Perez-Padilla, R1
Jarvis, D1
de Oliveira, PD1
Wehrmeister, FC1
Mir, S1
Wong, J1
Ryan, CM1
Bellingham, G1
Singh, M2
Waseem, R1
Eckert, DJ1
Chung, F1
Hegde, H1
Shimpi, N1
Panny, A1
Glurich, I1
Christie, P1
Acharya, A1
English, KL1
Downs, M1
Goetchius, E1
Buxton, R1
Ryder, JW1
Ploutz-Snyder, R1
Guilliams, M1
Scott, JM1
Ploutz-Snyder, LL1
Martens, C1
Goplen, FK1
Aasen, T1
Gjestad, R1
Nordfalk, KF1
Nordahl, SHG1
Inoue, T1
Soshi, S1
Kubota, M1
Marumo, K1
Mortensen, NP1
Caffaro, MM1
Patel, PR2
Uddin, MJ1
Aravamudhan, S1
Sumner, SJ1
Fennell, TR1
Gal, RL1
Cohen, NJ1
Kruger, D1
Beck, RW1
Bergenstal, RM1
Calhoun, P1
Cushman, T1
Haban, A1
Hood, K1
Johnson, ML1
McArthur, T1
Olson, BA1
Weinstock, RS1
Oser, SM1
Oser, TK1
Bugielski, B1
Strayer, H1
Aleppo, G1
Maruyama, H1
Hirayama, K1
Yamashita, M1
Ohgi, K1
Tsujimoto, R1
Takayasu, M1
Shimohata, H1
Kobayashi, M1
Buscagan, TM1
Rees, DC1
Jaborek, JR1
Zerby, HN1
Wick, MP1
Fluharty, FL1
Moeller, SJ1
Razavi, P1
Dickler, MN1
Shah, PD1
Toy, W1
Brown, DN1
Won, HH1
Li, BT1
Shen, R1
Vasan, N1
Modi, S1
Jhaveri, K1
Caravella, BA1
Patil, S1
Selenica, P1
Zamora, S1
Cowan, AM1
Comen, E1
Singh, A1
Covey, A1
Berger, MF1
Hudis, CA1
Norton, L1
Nagy, RJ1
Odegaard, JI1
Lanman, RB1
Solit, DB1
Robson, ME1
Lacouture, ME1
Brogi, E1
Reis-Filho, JS1
Moynahan, ME1
Scaltriti, M1
Chandarlapaty, S1
Papouskova, K1
Moravcova, M1
Masrati, G1
Ben-Tal, N1
Sychrova, H1
Zimmermannova, O1
Fang, J1
Fan, Y1
Luo, T2
Su, H1
Tsetseris, L1
Anthopoulos, TD1
Liu, SF1
Zhao, K1
Sacan, O1
Turkyilmaz, IB1
Bayrak, BB1
Mutlu, O1
Akev, N1
Yanardag, R1
Gruber, S1
Kamnoedboon, P1
Özcan, M1
Srinivasan, M1
Jo, YH1
Oh, HK1
Jeong, SY1
Lee, BG1
Zheng, J1
Guan, H1
Li, D2
Tan, H1
Maji, TK1
J R, A1
Mukherjee, S1
Alexander, R1
Mondal, A1
Das, S1
Sharma, RK1
Chakraborty, NK1
Dasgupta, K1
Sharma, AMR1
Hawaldar, R1
Pandey, M1
Naik, A1
Majumdar, K1
Pal, SK1
Adarsh, KV1
Ray, SK1
Karmakar, D1
Ma, Y2
Gao, W1
Ma, S1
Lin, W1
Zhou, T1
Wu, T1
Wu, Q1
Ye, C1
He, X1
Jiang, F1
Yuan, D1
Chen, Q1
Hong, M1
Chen, K1
Hussain, M1
Razi, SS1
Yildiz, EA1
Zhao, J1
Yaglioglu, HG1
Donato, MD1
Jiang, J1
Jamil, MI1
Zhan, X1
Chen, F1
Cheng, D1
Wu, CT1
Utsunomiya, T1
Ichii, T1
Fujinami, S1
Nakajima, K1
Sanchez, DM1
Raucci, U1
Ferreras, KN1
Martínez, TJ1
Mordi, NA1
Mordi, IR1
Singh, JS1
McCrimmon, RJ1
Struthers, AD1
Lang, CC1
Wang, XW1
Yuan, LJ1
Yang, Y1
Chen, WF1
Luo, R1
Yang, K1
Amarasiri, SS1
Attanayake, AP1
Arawwawala, LDAM1
Jayatilaka, KAPW1
Mudduwa, LKB1
Ogunsuyi, O2
Akanni, O1
Alabi, O1
Alimba, C1
Adaramoye, O1
Cambier, S1
Eswara, S1
Gutleb, AC1
Bakare, A1
Gu, Z1
Cong, J1
Pellegrini, M1
Palmieri, S1
Ricci, A1
Serio, A1
Paparella, A1
Lo Sterzo, C1
Jadeja, SD1
Vaishnav, J1
Mansuri, MS1
Shah, C1
Mayatra, JM1
Shah, A1
Begum, R1
Song, H2
Lian, Y1
Wan, T1
Schultz-Lebahn, A1
Skipper, MT1
Hvas, AM1
Larsen, OH1
Hijazi, Z1
Granger, CB1
Hohnloser, SH1
Westerbergh, J1
Lindbäck, J1
Alexander, JH1
Keltai, M1
Parkhomenko, A1
López-Sendón, JL1
Lopes, RD1
Siegbahn, A1
Wallentin, L1
El-Tarabany, MS1
Saleh, AA1
El-Araby, IE1
El-Magd, MA1
van Ginkel, MPH1
Schijven, MP1
van Grevenstein, WMU1
Schreuder, HWR1
Pereira, EDM1
da Silva, J1
Carvalho, PDS1
Grivicich, I1
Picada, JN1
Salgado Júnior, IB1
Vasques, GJ1
Pereira, MADS1
Reginatto, FH1
Ferraz, ABF1
Vasilenko, EA1
Gorshkova, EN1
Astrakhantseva, IV1
Drutskaya, MS1
Tillib, SV1
Nedospasov, SA1
Mokhonov, VV1
Nam, YW1
Cui, M1
Orfali, R1
Viegas, A1
Nguyen, M1
Mohammed, EHM1
Zoghebi, KA1
Rahighi, S1
Parang, K1
Patterson, KC1
Kahanovitch, U1
Gonçalves, CM1
Hablitz, JJ1
Staruschenko, A1
Mulkey, DK1
Olsen, ML1
Gu, L1
Cao, X1
Mukhtar, A1
Wu, K1
Zhang, YY1
Zhu, Y1
Lu, DZ1
Dong, W1
Bi, WJ1
Feng, XJ1
Wen, LM1
Sun, H1
Qi, MC1
Chang, CC1
Dinh, TK1
Lee, YA1
Wang, FN1
Sung, YC1
Yu, PL1
Chiu, SC1
Shih, YC1
Wu, CY1
Huang, YD1
Lu, TT1
Wan, D1
Sakizadeh, J1
Cline, JP1
Snyder, MA1
Kiely, CJ1
McIntosh, S1
Jiang, X1
Cao, JW1
Zhao, CK1
Yang, R1
Zhang, QY1
Chen, KJ2
He, Z1
Chen, B1
Wu, J1
Du, X1
Moore, J1
Blank, BR1
Eksterowicz, J1
Sutimantanapi, D1
Yuen, N1
Metzger, T1
Chan, B1
Huang, T1
Chen, X1
Duong, F1
Kong, W1
Chang, JH1
Sun, J1
Zavorotinskaya, T1
Ye, Q1
Junttila, MR1
Ndubaku, C1
Friedman, LS1
Fantin, VR1
Sun, D1
Fei, P1
Xie, Q1
Jiang, Y1
Feng, H1
Chang, Y1
Kang, H1
Xing, M1
Chen, J1
Shao, Z1
Yuan, C1
Wu, Y1
Allan, R1
Canham, K1
Wallace, R1
Singh, D1
Ward, J1
Cooper, A1
Newcomb, C1
Nammour, S1
El Mobadder, M1
Maalouf, E1
Namour, M1
Namour, A1
Rey, G1
Matamba, P1
Matys, J1
Zeinoun, T1
Grzech-Leśniak, K1
Segabinazi Peserico, C1
Garozi, L1
Zagatto, AM1
Machado, FA1
Hirth, JM1
Dinehart, EE1
Lin, YL1
Kuo, YF1
Nouri, SS1
Ritchie, C1
Volow, A1
Li, B2
McSpadden, S1
Dearman, K1
Kotwal, A1
Sudore, RL1
Ward, L1
Thakur, A1
Kondadasula, SV1
Ji, K1
Schalk, DL1
Bliemeister, E1
Ung, J1
Aboukameel, A1
Casarez, E1
Sloane, BF1
Lum, LG1
Xiao, M1
Feng, X1
Gao, R1
Du, B1
Brooks, T1
Zwirner, J1
Hammer, N1
Ondruschka, B1
Jermy, M1
Luengo, A1
Marzo, I1
Reback, M1
Daubit, IM1
Fernández-Moreira, V1
Metzler-Nolte, N1
Gimeno, MC1
Tonchev, I1
Heberman, D1
Peretz, A1
Medvedovsky, AT1
Gotsman, I1
Rashi, Y1
Poles, L1
Goland, S1
Perlman, GY1
Danenberg, HD1
Beeri, R1
Shuvy, M1
Fu, Q1
Yang, D1
Sarapulova, A1
Pang, Q1
Meng, Y1
Wei, L1
Ehrenberg, H1
Kim, CC1
Jeong, SH1
Oh, KH1
Nam, KT1
Sun, JY1
Ning, J1
Duan, Z1
Kershaw, SV1
Rogach, AL1
Gao, Z1
Wang, T1
Li, Q1
Cao, T1
Guo, L1
Fu, Y1
Seeger, ZL1
Izgorodina, EI1
Hue, S1
Beldi-Ferchiou, A1
Bendib, I1
Surenaud, M1
Fourati, S1
Frapard, T1
Rivoal, S1
Razazi, K1
Carteaux, G1
Delfau-Larue, MH1
Mekontso-Dessap, A1
Audureau, E1
de Prost, N1
Gao, SS1
Duangthip, D1
Lo, ECM1
Chu, CH1
Roberts, W1
Rosenheck, RA1
Miyake, T1
Kimoto, E1
Luo, L1
Mathialagan, S1
Horlbogen, LM1
Ramanathan, R1
Wood, LS1
Johnson, JG1
Le, VH1
Vourvahis, M1
Rodrigues, AD1
Muto, C1
Furihata, K1
Sugiyama, Y1
Kusuhara, H1
Gong, Q1
Song, W1
Sun, B1
Cao, P1
Gu, S1
Sun, X1
Zhou, G1
Toma, C1
Khandhar, S1
Zalewski, AM1
D'Auria, SJ1
Tu, TM1
Jaber, WA1
Cho, J2
Suwandaratne, NS1
Razek, S1
Choi, YH1
Piper, LFJ1
Watson, DF1
Banerjee, S1
Xie, S1
Lindsay, AP1
Bates, FS1
Lodge, TP1
Hao, Y1
Chapovetsky, A1
Liu, JJ1
Welborn, M1
Luna, JM1
Do, T1
Haiges, R1
Miller Iii, TF1
Marinescu, SC1
Lopez, SA1
Compter, I1
Eekers, DBP1
Hoeben, A1
Rouschop, KMA1
Reymen, B1
Ackermans, L1
Beckervordersantforth, J1
Bauer, NJC1
Anten, MM1
Wesseling, P1
Postma, AA1
De Ruysscher, D1
Lambin, P1
Qiang, L1
Yang, S1
Cui, YH1
He, YY1
Kumar, SK1
Jacobus, SJ1
Cohen, AD1
Weiss, M1
Callander, N1
Singh, AK1
Parker, TL1
Menter, A1
Parsons, B1
Kumar, P1
Kapoor, P1
Rosenberg, A1
Zonder, JA1
Faber, E1
Lonial, S1
Anderson, KC1
Richardson, PG1
Orlowski, RZ1
Wagner, LI1
Rajkumar, SV1
Li, G1
Hou, G1
Cui, J1
Xie, H1
Sun, Z1
Fang, Z1
Dunstand-Guzmán, E1
Hallal-Calleros, C1
Hernández-Velázquez, VM1
Canales-Vargas, EJ1
Domínguez-Roldan, R1
Pedernera, M1
Peña-Chora, G1
Flores-Pérez, I1
Kim, MJ1
Han, C1
White, K1
Park, HJ1
Ding, D1
Boyd, K1
Rothenberger, C1
Bose, U1
Carmichael, P1
Linser, PJ1
Tanokura, M1
Salvi, R1
Someya, S1
Samuni, A1
Goldstein, S1
Divya, KP1
Dharuman, V1
Feng, J2
Qian, Y1
Cheng, Q1
Ma, H1
Ren, X1
Wei, Q2
Pan, W1
Guo, J1
Situ, B1
An, T1
Zheng, L2
Augusto, S1
Ratola, N1
Tarín-Carrasco, P1
Jiménez-Guerrero, P1
Turco, M1
Schuhmacher, M1
Costa, S1
Teixeira, JP1
Costa, C1
Syed, A1
Marraiki, N1
Al-Rashed, S1
Elgorban, AM1
Yassin, MT1
Chankhanittha, T1
Nanan, S1
Sorokina, KN1
Samoylova, YV1
Gromov, NV1
Ogorodnikova, OL1
Parmon, VN1
Ye, J1
Liao, W1
Zhang, P1
Nabi, M1
Cai, Y1
Li, F1
Alsbou, EM1
Omari, KW1
Adeosun, WA1
Asiri, AM1
Marwani, HM1
Barral, M1
Jemal-Turki, A1
Beuvon, F1
Soyer, P1
Camparo, P1
Cornud, F1
Atwater, BD1
Jones, WS1
Loring, Z1
Friedman, DJ1
Namburath, M1
Papirio, S1
Moscariello, C1
Di Costanzo, N1
Pirozzi, F1
Alappat, BJ1
Sreekrishnan, TR1
Volpin, F1
Woo, YC1
Kim, H1
Freguia, S1
Jeong, N1
Choi, JS1
Phuntsho, S1
Shon, HK1
Domínguez-Zambrano, E1
Pedraza-Chaverri, J1
López-Santos, AL1
Medina-Campos, ON1
Cruz-Rivera, C1
Bueno-Hernández, F1
Espinosa-Cuevas, A1
Bulavaitė, A1
Dalgediene, I1
Michailoviene, V1
Pleckaityte, M1
Sauerbier, P1
Köhler, R1
Renner, G1
Militz, H1
Reddy, A1
Bozi, LHM1
Yaghi, OK1
Mills, EL2
Xiao, H1
Nicholson, HE1
Paschini, M1
Paulo, JA1
Garrity, R1
Laznik-Bogoslavski, D1
Ferreira, JCB1
Carl, CS1
Sjøberg, KA1
Wojtaszewski, JFP1
Jeppesen, JF1
Kiens, B1
Gygi, SP1
Richter, EA1
Mathis, D1
Chouchani, ET1
Rosen, MJ1
He, W1
Heinz, A1
Jahn, D1
Hiller, K2
Fremder, M1
Kim, SW1
Khamaysi, A1
Shimshilashvili, L1
Eini-Rider, H1
Park, IS1
Hadad, U1
Cheon, JH1
Ohana, E1
Peruzzotti-Jametti, L1
Bernstock, JD1
Vicario, N1
Costa, ASH2
Kwok, CK1
Leonardi, T1
Booty, LM1
Bicci, I1
Balzarotti, B1
Volpe, G1
Mallucci, G1
Manferrari, G1
Donegà, M1
Iraci, N1
Braga, A1
Hallenbeck, JM1
Murphy, MP2
Edenhofer, F1
Frezza, C3
Pluchino, S1
Nonnenmacher, Y1
Xiong, T1
Zhou, Y1
Song, Q1
She, L1
Xu, D1
Aa, J1
Wang, G1
Xie, Y1
Hua, YL1
Zhang, XS1
Yao, WL1
Ji, P1
Hu, JJ1
Wei, YM1
Macias-Ceja, DC1
Salvador, P1
Hernández, C1
Hausmann, M1
Rogler, G1
Hinojosa, J1
Genda, T1
Kondo, T1
Hino, S1
Sugiura, S1
Nishimura, N1
Morita, T1
Weinberg, SE1
Singer, BD1
Steinert, EM1
Martinez, CA1
Mehta, MM1
Martínez-Reyes, I1
Gao, P1
Helmin, KA1
Abdala-Valencia, H1
Sena, LA1
Schumacker, PT1
Turka, LA1
Chandel, NS1
Keiran, N1
Hernández-Alvarez, MI1
Ejarque, M1
Horrillo, D1
Maymó-Masip, E1
Rodríguez, MM1
Fradera, R1
de la Rosa, JV1
Jorba, R1
Megia, A1
Zorzano, A1
Medina-Gómez, G1
Serena, C1
Castrillo, A1
Bailey, JD1
Diotallevi, M1
Nicol, T1
McNeill, E1
Shaw, A1
Chuaiphichai, S1
Hale, A1
Starr, A1
Nandi, M1
Stylianou, E1
McShane, H1
Davis, S1
Fischer, R1
Kessler, BM1
McCullagh, J1
Channon, KM1
Crabtree, MJ1
Tannahill, GM1
Curtis, AM1
Adamik, J1
Palsson-McDermott, EM2
McGettrick, AF1
Goel, G1
Bernard, NJ1
Kelly, B2
Foley, NH1
Gardet, A1
Tong, Z1
Jany, SS1
Corr, SC2
Haneklaus, M1
Caffrey, BE1
Pierce, K1
Walmsley, S1
Beasley, FC1
Cummins, E1
Nizet, V1
Whyte, M1
Taylor, CT1
Lin, H1
Masters, SL1
Gottlieb, E2
Kelly, VP1
Clish, C1
Auron, PE1
Xavier, RJ2
O'Neill, LA4
Jakobsdottir, G1
Xu, J1
Molin, G1
Ahrné, S1
Nyman, M1
Mills, E1
Gattu, AK1
Birkenfeld, AL1
Iwakiri, Y1
Jay, S1
Saltzman, M1
Doll, J1
Protiva, P1
Samuel, VT1
Crawford, SE1
Chung, C1
Volchegorskii, IA2
Pravdin, EV2
Uzlova, TV2
Fei, F1
Lee, KM1
McCarry, BE1
Bowdish, DM1
Lampropoulou, V1
Sergushichev, A1
Bambouskova, M1
Nair, S1
Vincent, EE1
Loginicheva, E1
Cervantes-Barragan, L1
Ma, X1
Huang, SC1
Griss, T1
Weinheimer, CJ1
Khader, S1
Randolph, GJ1
Pearce, EJ1
Jones, RG1
Diwan, A1
Diamond, MS1
Artyomov, MN1
Logan, A1
Varma, M1
Bryant, CE1
Tourlomousis, P1
Däbritz, JHM1
Latorre, I1
McManus, G1
Ryan, D1
Jacobs, HT1
Szibor, M1
Braun, T1
Jiang, S1
ElAzzouny, M1
Tom, CT1
Evans, CR1
Olson, LL1
Tanga, MJ1
Gallagher, KA1
Martin, BR1
Burant, CF1
Yokoyama, A1
Matsuno, H1
Yamamoto, S1
Kawasaki, T1
Kohgo, T1
Uo, M1
Watari, F1
Nakasu, M1
Fujisawa, T1
Igeta, K1
Odake, S1
Morita, Y1
Yasuda, J1
Morikawa, T1

Reviews

9 reviews available for succinic acid and Inflammation

ArticleYear
Mitochondria and ischemia reperfusion injury.
    Current opinion in organ transplantation, 2022, 10-01, Volume: 27, Issue:5

    Topics: Humans; Inflammation; Ischemia; Mitochondria; Reperfusion Injury; Succinic Acid

2022
Tissue-specific macrophage immunometabolism.
    Current opinion in immunology, 2023, Volume: 84

    Topics: Energy Metabolism; Humans; Immunity; Inflammation; Macrophages; Succinic Acid

2023
Cytokine-like Roles for Metabolites in Immunity.
    Molecular cell, 2020, 06-04, Volume: 78, Issue:5

    Topics: Animals; Carboxylic Acids; Citric Acid Cycle; Cytokines; Energy Metabolism; Humans; Immunity; Inflam

2020
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Complexity of macrophage metabolism in infection.
    Current opinion in biotechnology, 2021, Volume: 68

    Topics: Citric Acid Cycle; Humans; Inflammation; Macrophage Activation; Macrophages; Succinic Acid

2021
Biochemistry of proinflammatory macrophage activation.
    Cellular and molecular life sciences : CMLS, 2018, Volume: 75, Issue:12

    Topics: Animals; Communicable Diseases; Energy Metabolism; Glycolysis; Humans; Inflammation; Macrophage Acti

2018
The Warburg effect then and now: from cancer to inflammatory diseases.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 2013, Volume: 35, Issue:11

    Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Citr

2013
Succinate: a metabolic signal in inflammation.
    Trends in cell biology, 2014, Volume: 24, Issue:5

    Topics: Adaptive Immunity; Animals; Citric Acid Cycle; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Im

2014
Succinate in the cancer-immune cycle.
    Cancer letters, 2017, 04-01, Volume: 390

    Topics: Citric Acid Cycle; Humans; Inflammation; Neoplasms; Succinic Acid

2017

Trials

3 trials available for succinic acid and Inflammation

ArticleYear
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
    Annales medico-psychologiques, 2021, Volume: 179, Issue:2

    Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli

2021
Effects of 3-hydroxypyridine derivatives and succinic acid on endometrial leukocyte infiltration, cytokinemia and related affective symptoms during exacerbation of the chronic inflammation of the uterus and adnexa.
    Bulletin of experimental biology and medicine, 2014, Volume: 156, Issue:3

    Topics: Adnexal Diseases; Chronic Disease; Cytokines; Endometrium; Female; Humans; Inflammation; Leukocytes;

2014
[Effect of 3-oxypyridine and succinic acid derivatives on affective status in recrudescence of inflammatory diseases of uterus and its appendages].
    Eksperimental'naia i klinicheskaia farmakologiia, 2012, Volume: 75, Issue:11

    Topics: Adnexa Uteri; Adolescent; Adult; Antioxidants; Brain; Depressive Disorder; Female; Genital Diseases,

2012

Other Studies

37 other studies available for succinic acid and Inflammation

ArticleYear
Paeoniflorin alleviates CFA-induced inflammatory pain by inhibiting TRPV1 and succinate/SUCNR1-HIF-1α/NLPR3 pathway.
    International immunopharmacology, 2021, Volume: 101, Issue:Pt B

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Freund's Adjuvant; Ganglia,

2021
Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate.
    Microbiome, 2022, 08-25, Volume: 10, Issue:1

    Topics: Animals; Bacteroidetes; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Humans; Inflammati

2022
Influence of Microbial Metabolites and Itaconic Acid Involved in Bacterial Inflammation on the Activity of Mitochondrial Enzymes and the Protective Role of Alkalization.
    International journal of molecular sciences, 2022, Aug-14, Volume: 23, Issue:16

    Topics: Glutamate Dehydrogenase; Glutamic Acid; Humans; Inflammation; Mitochondria; Oxidation-Reduction; Pyr

2022
Targeting the succinate receptor effectively inhibits periodontitis.
    Cell reports, 2022, 09-20, Volume: 40, Issue:12

    Topics: Alveolar Bone Loss; Animals; Dysbiosis; Humans; Inflammation; Mice; Mice, Knockout; Periodontal Dise

2022
Microbial metabolite succinate activates solitary chemosensory cells in the human sinonasal epithelium.
    International forum of allergy & rhinology, 2023, Volume: 13, Issue:8

    Topics: Antimicrobial Peptides; Calcium; Chronic Disease; Epithelial Cells; Epithelium; Humans; Inflammation

2023
Succinate and mitochondrial DNA trigger atopic march from atopic dermatitis to intestinal inflammation.
    The Journal of allergy and clinical immunology, 2023, Volume: 151, Issue:4

    Topics: Animals; Dermatitis, Atopic; DNA, Mitochondrial; Food Hypersensitivity; Immunity, Innate; Inflammati

2023
Succinate pretreatment attenuates intestinal ischemia-reperfusion injury by inhibiting necroptosis and inflammation via upregulating Klf4.
    International immunopharmacology, 2023, Volume: 120

    Topics: Animals; Inflammation; Intestines; Kruppel-Like Factor 4; Mice; Necroptosis; Rats; Reperfusion Injur

2023
Cross talk between Paneth and tuft cells drives dysbiosis and inflammation in the gut mucosa.
    Proceedings of the National Academy of Sciences of the United States of America, 2023, 06-20, Volume: 120, Issue:25

    Topics: Dysbiosis; Humans; Inflammation; Mucous Membrane; Paneth Cells; Succinates; Succinic Acid

2023
Succinate mediates inflammation-induced adrenocortical dysfunction.
    eLife, 2023, 07-14, Volume: 12

    Topics: Adrenocorticotropic Hormone; Animals; Glucocorticoids; Inflammation; Mice; Proteomics; Succinic Acid

2023
Succinate signaling attenuates high-fat diet-induced metabolic disturbance and intestinal barrier dysfunction.
    Pharmacological research, 2023, Volume: 194

    Topics: Animals; Diet, High-Fat; Gastrointestinal Diseases; Inflammation; Intestinal Diseases; Mice; Mice, I

2023
Refined fiber inulin promotes inflammation-associated colon tumorigenesis by modulating microbial succinate production.
    Cancer reports (Hoboken, N.J.), 2023, Volume: 6, Issue:11

    Topics: Animals; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Colorectal Neo

2023
Role of succinate in airway epithelial cell regulation following traumatic lung injury.
    JCI insight, 2023, 09-22, Volume: 8, Issue:18

    Topics: Animals; Epithelial Cells; Humans; Hypoxia; Inflammation; Lung; Lung Injury; Mice; Respiratory Distr

2023
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
    Biomolecules, 2019, 09-13, Volume: 9, Issue:9

    Topics: Animals; Cell Line; Disease Models, Animal; Electric Impedance; Gene Expression Regulation; Inflamma

2019
Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase-HIF-1α axis.
    Biochemical and biophysical research communications, 2020, 01-29, Volume: 522, Issue:1

    Topics: Bacteroidaceae Infections; Cells, Cultured; Glycolysis; Host-Pathogen Interactions; Humans; Hypoxia-

2020
Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota.
    Frontiers in cellular and infection microbiology, 2019, Volume: 9

    Topics: Anti-Inflammatory Agents; Chemokines; Cytokines; Epithelial Cells; Fatty Acids, Volatile; Female; HI

2019
Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development.
    Cells, 2020, 04-29, Volume: 9, Issue:5

    Topics: Animals; Cadherins; Crohn Disease; Epithelial Cells; Fibrosis; Fistula; Humans; Inflammation; Intest

2020
pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.
    Cell, 2020, 10-01, Volume: 183, Issue:1

    Topics: Animals; Humans; Hydrogen-Ion Concentration; Inflammation; Mice; Mitochondria; Monocarboxylic Acid T

2020
Could a Small Population of Epithelial Cells Get "Tuft" With Crohn's Disease?
    Gastroenterology, 2020, Volume: 159, Issue:6

    Topics: Crohn Disease; Epithelial Cells; Humans; Inflammation; Intestinal Mucosa; Succinic Acid

2020
A transepithelial pathway delivers succinate to macrophages, thus perpetuating their pro-inflammatory metabolic state.
    Cell reports, 2021, 08-10, Volume: 36, Issue:6

    Topics: Animals; Bacteria; Disease Models, Animal; Epithelial Cells; Feces; Gastrointestinal Microbiome; Gen

2021
Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation.
    Cell stem cell, 2018, 03-01, Volume: 22, Issue:3

    Topics: Animals; Cell Line; Central Nervous System; Chronic Disease; Dinoprostone; Female; Humans; Inflammat

2018
Glycosylation-enhanced biocompatibility of the supramolecular hydrogel of an anti-inflammatory drug for topical suppression of inflammation.
    Acta biomaterialia, 2018, Volume: 73

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Autoimmune Diseases; Biocompatible Mater

2018
Curcumin inhibits hepatic stellate cell activation via suppression of succinate-associated HIF-1α induction.
    Molecular and cellular endocrinology, 2018, 11-15, Volume: 476

    Topics: Animals; Curcumin; Diet, High-Fat; Hepatic Stellate Cells; Hypoxia-Inducible Factor 1, alpha Subunit

2018
Urinary metabolomics analysis reveals the effect of volatile oil from Angelica sinensis on LPS-induced inflammation rats.
    Biomedical chromatography : BMC, 2019, Volume: 33, Issue:2

    Topics: Angelica sinensis; Animals; Anti-Inflammatory Agents; Biomarkers; Inflammation; Lipopolysaccharides;

2019
Succinate receptor mediates intestinal inflammation and fibrosis.
    Mucosal immunology, 2019, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Animals; Cells, Cultured; Colitis; Crohn Disease; Disease Models, Animal; Female;

2019
The Impact of Fructo-Oligosaccharides on Gut Permeability and Inflammatory Responses in the Cecal Mucosa Quite Differs between Rats Fed Semi-Purified and Non-Purified Diets.
    Journal of nutritional science and vitaminology, 2018, Volume: 64, Issue:5

    Topics: Animal Feed; Animals; Bacterial Translocation; Cecum; Chromium; Cytokines; Diet; Digestion; Edetic A

2018
Mitochondrial complex III is essential for suppressive function of regulatory T cells.
    Nature, 2019, Volume: 565, Issue:7740

    Topics: Animals; DNA Demethylation; DNA Methylation; Electron Transport; Electron Transport Complex III; Fem

2019
SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity.
    Nature immunology, 2019, Volume: 20, Issue:5

    Topics: Adipose Tissue; Animals; Cells, Cultured; Cytokines; Gene Expression Profiling; Humans; Inflammation

2019
Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.
    Cell reports, 2019, 07-02, Volume: 28, Issue:1

    Topics: Animals; Biopterins; Citric Acid Cycle; Electron Transport; Endotoxemia; Glycolysis; GTP Cyclohydrol

2019
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
    Nature, 2013, Apr-11, Volume: 496, Issue:7444

    Topics: Animals; Bone Marrow Cells; Citric Acid Cycle; Deoxyglucose; Down-Regulation; gamma-Aminobutyric Aci

2013
High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Body Weight; Butyrates; Chemokine CCL2; Cholesterol; Colon; Diet; Diet, High-Fat; Dietary F

2013
Pigment epithelium-derived factor (PEDF) suppresses IL-1β-mediated c-Jun N-terminal kinase (JNK) activation to improve hepatocyte insulin signaling.
    Endocrinology, 2014, Volume: 155, Issue:4

    Topics: Adipocytes; Animals; Eye Proteins; Gene Expression Regulation; Glucose Tolerance Test; Hepatocytes;

2014
Age-associated metabolic dysregulation in bone marrow-derived macrophages stimulated with lipopolysaccharide.
    Scientific reports, 2016, Mar-04, Volume: 6

    Topics: Aging; Animals; Arginine; Cells, Cultured; gamma-Aminobutyric Acid; Glycolysis; Inflammation; Lipopo

2016
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
    Cell metabolism, 2016, 07-12, Volume: 24, Issue:1

    Topics: Animals; Cell Respiration; Female; Inflammation; Lipopolysaccharides; Macrophage Activation; Macroph

2016
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
    Cell, 2016, Oct-06, Volume: 167, Issue:2

    Topics: Adenosine Triphosphate; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Citric Acid Cycle; Glyco

2016
Dimethyl Itaconate Is Not Metabolized into Itaconate Intracellularly.
    The Journal of biological chemistry, 2017, 03-24, Volume: 292, Issue:12

    Topics: Animals; Cells, Cultured; Inflammation; Lipopolysaccharides; Macrophages; Metabolome; Metabolomics;

2017
Tissue response to a newly developed calcium phosphate cement containing succinic acid and carboxymethyl-chitin.
    Journal of biomedical materials research. Part A, 2003, Mar-01, Volume: 64, Issue:3

    Topics: Absorbable Implants; Animals; Biocompatible Materials; Bone Cements; Bone Substitutes; Calcium Phosp

2003
Highly water-soluble matrix metalloproteinases inhibitors and their effects in a rat adjuvant-induced arthritis model.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:8

    Topics: ADAM Proteins; ADAM17 Protein; Amides; Animals; Arthritis; Disease Models, Animal; Enzyme Inhibitors

2002