succinic acid has been researched along with Hypoxia-Ischemia, Brain in 4 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sahni, PV | 1 |
| Zhang, J | 1 |
| Sosunov, S | 1 |
| Galkin, A | 1 |
| Niatsetskaya, Z | 1 |
| Starkov, A | 1 |
| Brookes, PS | 1 |
| Ten, VS | 1 |
| Boruczkowski, D | 1 |
| Pujal, JM | 1 |
| Zdolińska-Malinowska, I | 1 |
| Reinke, SN | 1 |
| Walsh, BH | 1 |
| Boylan, GB | 1 |
| Sykes, BD | 1 |
| Kenny, LC | 1 |
| Murray, DM | 1 |
| Broadhurst, DI | 1 |
| Hamel, D | 1 |
| Sanchez, M | 1 |
| Duhamel, F | 1 |
| Roy, O | 1 |
| Honoré, JC | 1 |
| Noueihed, B | 1 |
| Zhou, T | 1 |
| Nadeau-Vallée, M | 1 |
| Hou, X | 1 |
| Lavoie, JC | 1 |
| Mitchell, G | 1 |
| Mamer, OA | 1 |
| Chemtob, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| BiHiVE 2 Study. The Investigation and Validation of Predictive Biomarkers in Hypoxic-ischaemic Encephalopathy.[NCT02019147] | 500 participants (Actual) | Observational | 2012-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for succinic acid and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Autologous cord blood in children with cerebral palsy: a review.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Brain Diseases; Brain Injuries; Carnitine; Cerebral Pal | 2019 |
3 other studies available for succinic acid and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Krebs cycle metabolites and preferential succinate oxidation following neonatal hypoxic-ischemic brain injury in mice.
Topics: Animals; Animals, Newborn; Chromatography, High Pressure Liquid; Citric Acid Cycle; Electrons; Hydro | 2018 |
1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy.
Topics: 3-Hydroxybutyric Acid; Acetone; Asphyxia Neonatorum; Case-Control Studies; Female; Fetal Blood; Glyc | 2013 |
G-protein-coupled receptor 91 and succinate are key contributors in neonatal postcerebral hypoxia-ischemia recovery.
Topics: Angiogenic Proteins; Animals; Animals, Newborn; Astrocytes; Cell Line; Cerebral Cortex; Cerebral Inf | 2014 |