succinic acid has been researched along with Hemorrhagic Shock in 3 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glutamine metabolism contributes to increased succinate concentration in plasma during hemorrhagic shock." | 7.83 | Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock. ( Bacon, AW; Banerjee, A; D'Alessandro, A; Fragoso, M; Hansen, KC; Moore, EE; Moore, HB; Peltz, ED; Reisz, JA; Silliman, CC; Slaughter, AL; Wither, MJ, 2016) |
| "Dimethyl malonate (DMM) is a competitive inhibitor of SI dehydrogenase, which has been shown to reduce SI accumulation and protect against reperfusion injury." | 5.72 | Dimethyl malonate slows succinate accumulation and preserves cardiac function in a swine model of hemorrhagic shock. ( Abdullah, S; Aras, OAZ; Bitonti, N; Cotton-Betteridge, A; Drury, RH; Duchesne, J; Jackson-Weaver, O; Karim, M; Kosowski, EM; Packer, J; Shaheen, F; Taghavi, S; Toraih, E, 2022) |
| "Glutamine metabolism contributes to increased succinate concentration in plasma during hemorrhagic shock." | 3.83 | Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock. ( Bacon, AW; Banerjee, A; D'Alessandro, A; Fragoso, M; Hansen, KC; Moore, EE; Moore, HB; Peltz, ED; Reisz, JA; Silliman, CC; Slaughter, AL; Wither, MJ, 2016) |
| "Dimethyl malonate (DMM) is a competitive inhibitor of SI dehydrogenase, which has been shown to reduce SI accumulation and protect against reperfusion injury." | 1.72 | Dimethyl malonate slows succinate accumulation and preserves cardiac function in a swine model of hemorrhagic shock. ( Abdullah, S; Aras, OAZ; Bitonti, N; Cotton-Betteridge, A; Drury, RH; Duchesne, J; Jackson-Weaver, O; Karim, M; Kosowski, EM; Packer, J; Shaheen, F; Taghavi, S; Toraih, E, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Taghavi, S | 1 |
| Abdullah, S | 1 |
| Toraih, E | 1 |
| Packer, J | 1 |
| Drury, RH | 1 |
| Aras, OAZ | 1 |
| Kosowski, EM | 1 |
| Cotton-Betteridge, A | 1 |
| Karim, M | 1 |
| Bitonti, N | 1 |
| Shaheen, F | 1 |
| Duchesne, J | 1 |
| Jackson-Weaver, O | 1 |
| Reisz, JA | 2 |
| Wither, MJ | 2 |
| Moore, EE | 2 |
| Slaughter, AL | 2 |
| Moore, HB | 2 |
| Ghasabyan, A | 1 |
| Chandler, J | 1 |
| Schaub, LJ | 1 |
| Fragoso, M | 2 |
| Nunns, G | 1 |
| Silliman, CC | 2 |
| Hansen, KC | 2 |
| Banerjee, A | 2 |
| Sheppard, FR | 1 |
| D'Alessandro, A | 2 |
| Bacon, AW | 1 |
| Peltz, ED | 1 |
3 other studies available for succinic acid and Hemorrhagic Shock
| Article | Year |
|---|---|
Dimethyl malonate slows succinate accumulation and preserves cardiac function in a swine model of hemorrhagic shock.
Topics: Animals; Calcium; Disease Models, Animal; Humans; Lactates; Malonates; Resuscitation; Shock, Hemorrh | 2022 |
All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Disease Models, Animal; Gas Chromatograph | 2018 |
Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock.
Topics: Animals; Brain; Disease Models, Animal; Glutamine; Liver; Lung; Myocardium; Rats; Rats, Sprague-Dawl | 2016 |