succinic acid has been researched along with Endometrial Neoplasms in 3 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Endometrial Neoplasms: Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uterine endometrial cancer (UEC) is an estrogen-related tumor." | 1.91 | Active Estrogen-Succinate Metabolism Promotes Heme Accumulation and Increases the Proliferative and Invasive Potential of Endometrial Cancer Cells. ( Abudukeyoumu, A; Hou, DY; Lai, ZZ; Li, MQ; Lu, JJ; Tao, X; Wu, JN; Xie, F; Zhang, X; Zhu, XY, 2023) |
| "Treatment with melatonin restricted estrogen/UBC/SDHB-induced succinate accumulation and upregulated expression of KCNQ1 and reduced the succinate-mediated growth of UECC in vitro and in vivo." | 1.56 | Melatonin alleviates progression of uterine endometrial cancer by suppressing estrogen/ubiquitin C/SDHB-mediated succinate accumulation. ( Chang, K; Chang, R; Gu, C; Li, M; Qiu, X; Qu, Y; Wang, J; Wang, Y; Xie, F; Yang, H; Ye, J; Zhang, B, 2020) |
| "Succinic acid has no adverse effects because it is metabolized by body cells and has a role in the tricarboxylic acid cycle (TCA) as a cycle media component." | 1.48 | A new target for the treatment of endometrium cancer by succinic acid. ( Cakmakoglu, B; Catmakas, T; Iplik, ES, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, JJ | 1 |
| Zhang, X | 1 |
| Abudukeyoumu, A | 1 |
| Lai, ZZ | 1 |
| Hou, DY | 1 |
| Wu, JN | 1 |
| Tao, X | 1 |
| Li, MQ | 1 |
| Zhu, XY | 1 |
| Xie, F | 2 |
| Gu, C | 1 |
| Yang, H | 1 |
| Chang, K | 1 |
| Zhang, B | 1 |
| Ye, J | 1 |
| Chang, R | 1 |
| Qiu, X | 1 |
| Wang, Y | 1 |
| Qu, Y | 1 |
| Wang, J | 1 |
| Li, M | 1 |
| Iplik, ES | 1 |
| Catmakas, T | 1 |
| Cakmakoglu, B | 1 |
3 other studies available for succinic acid and Endometrial Neoplasms
| Article | Year |
|---|---|
Active Estrogen-Succinate Metabolism Promotes Heme Accumulation and Increases the Proliferative and Invasive Potential of Endometrial Cancer Cells.
Topics: Aminolevulinic Acid; Endometrial Neoplasms; Estrogens; Female; Heme; Humans; Receptors, Estrogen; Su | 2023 |
Melatonin alleviates progression of uterine endometrial cancer by suppressing estrogen/ubiquitin C/SDHB-mediated succinate accumulation.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Endometrial Neoplasms; Estrogens; Female; | 2020 |
A new target for the treatment of endometrium cancer by succinic acid.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Caspase 3; Cell Line; Cell Line, Tumor; Endometrial Neo | 2018 |