succinic acid has been researched along with Disease Models, Animal in 81 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glutamine metabolism contributes to increased succinate concentration in plasma during hemorrhagic shock." | 7.83 | Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock. ( Bacon, AW; Banerjee, A; D'Alessandro, A; Fragoso, M; Hansen, KC; Moore, EE; Moore, HB; Peltz, ED; Reisz, JA; Silliman, CC; Slaughter, AL; Wither, MJ, 2016) |
| "Alloxan and oxidative stress, which have been detected in livers of laboratory animals shortly after in vivo alloxan administration, cause in vitro mitochondrial dysfunction, thus questioning alloxan diabetes as an acceptable model for type 1 diabetes, a model that cannot legitimately be used to investigate mitochondrial metabolism in a diabetic state." | 7.77 | Early hyperglycemia following alloxan administration in vivo is not associated with altered hepatic mitochondrial function: acceptable model for type 1 diabetes? ( Alvarez-Bustamante, JA; Rendon, DA, 2011) |
| "Dimethyl malonate (DMM) is a competitive inhibitor of SI dehydrogenase, which has been shown to reduce SI accumulation and protect against reperfusion injury." | 5.72 | Dimethyl malonate slows succinate accumulation and preserves cardiac function in a swine model of hemorrhagic shock. ( Abdullah, S; Aras, OAZ; Bitonti, N; Cotton-Betteridge, A; Drury, RH; Duchesne, J; Jackson-Weaver, O; Karim, M; Kosowski, EM; Packer, J; Shaheen, F; Taghavi, S; Toraih, E, 2022) |
| "Glutamine metabolism contributes to increased succinate concentration in plasma during hemorrhagic shock." | 3.83 | Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock. ( Bacon, AW; Banerjee, A; D'Alessandro, A; Fragoso, M; Hansen, KC; Moore, EE; Moore, HB; Peltz, ED; Reisz, JA; Silliman, CC; Slaughter, AL; Wither, MJ, 2016) |
| "Alloxan and oxidative stress, which have been detected in livers of laboratory animals shortly after in vivo alloxan administration, cause in vitro mitochondrial dysfunction, thus questioning alloxan diabetes as an acceptable model for type 1 diabetes, a model that cannot legitimately be used to investigate mitochondrial metabolism in a diabetic state." | 3.77 | Early hyperglycemia following alloxan administration in vivo is not associated with altered hepatic mitochondrial function: acceptable model for type 1 diabetes? ( Alvarez-Bustamante, JA; Rendon, DA, 2011) |
| "Selenite cataract was induced by injecting 13-day-old Sprague-Dawley rat pups with a single subcutaneous dose of sodium selenite (3." | 3.73 | Biochemical changes in selenite cataract model measured by high-resolution MAS H NMR spectroscopy. ( Fris, M; Midelfart, A; Saether, O; Tessem, MB, 2006) |
| "Our previous studies showed a low oral bioavailability and a predominant distribution of major XLP ingredients in the gut." | 1.91 | Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats. ( Chen, FL; Deng, XH; Hu, YX; Liu, CS; Luo, ZY; Qiu, CW, 2023) |
| "Dimethyl malonate (DMM) is a competitive inhibitor of SI dehydrogenase, which has been shown to reduce SI accumulation and protect against reperfusion injury." | 1.72 | Dimethyl malonate slows succinate accumulation and preserves cardiac function in a swine model of hemorrhagic shock. ( Abdullah, S; Aras, OAZ; Bitonti, N; Cotton-Betteridge, A; Drury, RH; Duchesne, J; Jackson-Weaver, O; Karim, M; Kosowski, EM; Packer, J; Shaheen, F; Taghavi, S; Toraih, E, 2022) |
| "Upon reoxygenation after anoxia the succinate that had accumulated during anoxia was rapidly oxidized in association with extensive mitochondrial superoxide/hydrogen peroxide production and cell injury, mimicking reperfusion injury." | 1.72 | Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury. ( Allen, FM; Bates, GR; Burger, N; Casey, AM; Gruszczyk, AV; Hall, AR; James, AM; Krieg, T; Murphy, MP; Prag, HA; Saeb-Parsy, K, 2022) |
| "Psoriasis is a chronic, inflammatory skin disease." | 1.62 | Abnormal composition of microbiota in the gut and skin of imiquimod-treated mice. ( Chang, L; Fujita, Y; Hashimoto, K; Hashimoto, Y; Ishima, T; Matsue, H; Shinno-Hashimoto, H; Wei, Y, 2021) |
| "To induce the progression of NAFLD to nonalcoholic steatohepatitis (NASH), C57BL/6J mice were fed a Western-style diet (WD) or control diet for 30 weeks." | 1.62 | Western Diet Decreases the Liver Mitochondrial Oxidative Flux of Succinate: Insight from a Murine NAFLD Model. ( Červinková, Z; Elkalaf, M; Kučera, O; Melek, J; Peterová, E; Podhola, M; Rychtrmoc, D; Staňková, P; Zubáňová, V, 2021) |
| "Amoxicillin treated rats had lower BP compared with untreated rats." | 1.56 | Exposure to Amoxicillin in Early Life Is Associated With Changes in Gut Microbiota and Reduction in Blood Pressure: Findings From a Study on Rat Dams and Offspring. ( Chakraborty, S; Cheng, X; Chiu, N; Galla, S; Joe, B; Mell, B; Vijay-Kumar, M; Wenceslau, CF; Yeo, JY, 2020) |
| "Paraganglioma and pheochromocytoma are examples, whose etiology and therapy are complicated by the absence of representative cell lines or animal models." | 1.51 | Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor. ( Braun, MM; Chen, C; Damjanac, T; Hu, J; Maher, LJ; Zhang, Y, 2019) |
| "Stroke was induced in mice by middle cerebral artery occlusion for 90 minutes, followed by reperfusion." | 1.46 | Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice. ( Berressem, D; Eckert, GP; Klein, J; Koch, K; Konietzka, J; Thinnes, A, 2017) |
| "Acute treatment of postsymptomatic SCA1 mice with succinic acid, a complex II (succinate dehydrogenase) electron donor to bypass complex I dysfunction, ameliorated cerebellar OXPHOS dysfunction, reduced cerebellar pathology and improved motor behavior." | 1.46 | Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model. ( Berry, G; Carbone, E; Ferro, A; Frederick, K; Hartman, J; Ingram, MA; Ives, S; Lagalwar, S; Marzouk, E; Nguyen, D; Polley, K; Possidente, B; Possidente, T; Reynolds, TH; Siegel, A; Villegas, M; Zhang, J, 2017) |
| " In order to probe an alternative dosing design that would preclude this effect, we studied the efficacy of a low dose of the antidepressant imipramine (7 mg/kg/day) delivered via food pellets." | 1.42 | Animal Models of Depression and Drug Delivery with Food as an Effective Dosing Method: Evidences from Studies with Celecoxib and Dicholine Succinate. ( Araújo-Correia, M; Cline, BH; Costa-Nunes, JP; Dolgov, O; Kubatiev, A; Markova, N; Steinbusch, HW; Strekalova, T; Valença, A; Yeritsyan, N, 2015) |
| "When hypertension was reduced using captopril, vitreoretinal succinate returned to baseline levels." | 1.40 | Cyclic stretch and hypertension increase retinal succinate: potential mechanisms for exacerbation of ocular neovascularization by mechanical stress. ( Kinoshita, H; Kitaoka, T; Kusano, M; Maekawa, Y; Maki, T; Matsumoto, M; Suzuma, K; Uematsu, M, 2014) |
| "The currently available treatments for Chagas disease show limited therapeutic potential and are associated with serious side effects." | 1.40 | In vivo anti-Trypanosoma cruzi activity of hydro-ethanolic extract and isolated active principles from Aristeguietia glutinosa and mechanism of action studies. ( Cerecetto, H; Chiriboga, X; de Bilbao, NI; González, M; Miño, P; Serna, E; Torres, S; Varela, J; Yaluff, G, 2014) |
| "Neuroprotective properties of ketosis may be related to the upregulation of hypoxia inducible factor (HIF)-1alpha, a primary constituent associated with hypoxic angiogenesis and a regulator of neuroprotective responses." | 1.35 | Neuroprotection in diet-induced ketotic rat brain after focal ischemia. ( Emancipator, DS; LaManna, JC; Lust, WD; Puchowicz, MA; Pundik, S; Valerio, J; Xu, K; Zechel, JL, 2008) |
| "Pretreatment with mangiferin (100 mg/kg b." | 1.33 | Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infarcted rats. ( Jainu, M; Prabhu, S; Sabitha, KE; Shyamala Devi, CS, 2006) |
| "Mice with juvenile visceral steatosis (JVS) develop remarkable cardiac hypertrophy and exhibit an increased number of mitochondria in their heart." | 1.32 | Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis. ( Arakaki, N; Higuti, T; Himeda, T; Kuwajima, M; Morokami, K; Shibata, H; Suenaga, M, 2003) |
| "The succinic acid prevented the increase of cholesterol, triglyceride and low density lipoproteins in the blood." | 1.30 | Prophylaxis of encephalopathies and risk factors of atherogenesis development in the postresuscitation period in rats by means of succinic acid. ( Avruschenko, MS; Gulyaeva, NV; Gurvitch, AM; Lazareva, NA; Mutuskina, EA; Onufriev, MV; Pylova, SI; Stepanichev, MY; Trubina, IE; Volkov, AV; Zarzhetsky, YV, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (7.41) | 18.2507 |
| 2000's | 19 (23.46) | 29.6817 |
| 2010's | 34 (41.98) | 24.3611 |
| 2020's | 22 (27.16) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 3 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Fujiwara, H | 1 |
| Seike, K | 1 |
| Brooks, MD | 1 |
| Mathew, AV | 1 |
| Kovalenko, I | 1 |
| Pal, A | 1 |
| Lee, HJ | 2 |
| Peltier, D | 1 |
| Kim, S | 1 |
| Liu, C | 4 |
| Oravecz-Wilson, K | 1 |
| Li, L | 1 |
| Sun, Y | 2 |
| Byun, J | 1 |
| Maeda, Y | 1 |
| Wicha, MS | 1 |
| Saunders, TL | 1 |
| Rehemtulla, A | 1 |
| Lyssiotis, CA | 1 |
| Pennathur, S | 1 |
| Reddy, P | 1 |
| Belosludtseva, NV | 1 |
| Kireeva, TA | 1 |
| Belosludtsev, KN | 1 |
| Khunderyakova, NV | 1 |
| Mironova, GD | 1 |
| Yang, Y | 2 |
| Tapias, V | 1 |
| Acosta, D | 1 |
| Xu, H | 1 |
| Chen, H | 2 |
| Bhawal, R | 1 |
| Anderson, ET | 1 |
| Ivanova, E | 1 |
| Lin, H | 1 |
| Sagdullaev, BT | 1 |
| Chen, J | 2 |
| Klein, WL | 1 |
| Viola, KL | 1 |
| Gandy, S | 1 |
| Haroutunian, V | 1 |
| Beal, MF | 3 |
| Eliezer, D | 1 |
| Zhang, S | 3 |
| Gibson, GE | 1 |
| Taghavi, S | 1 |
| Abdullah, S | 1 |
| Toraih, E | 1 |
| Packer, J | 1 |
| Drury, RH | 1 |
| Aras, OAZ | 1 |
| Kosowski, EM | 1 |
| Cotton-Betteridge, A | 1 |
| Karim, M | 1 |
| Bitonti, N | 1 |
| Shaheen, F | 1 |
| Duchesne, J | 1 |
| Jackson-Weaver, O | 1 |
| Gruszczyk, AV | 3 |
| Casey, AM | 1 |
| James, AM | 5 |
| Prag, HA | 3 |
| Burger, N | 2 |
| Bates, GR | 1 |
| Hall, AR | 2 |
| Allen, FM | 1 |
| Krieg, T | 5 |
| Saeb-Parsy, K | 4 |
| Murphy, MP | 5 |
| Preethy, S | 1 |
| Ikewaki, N | 1 |
| Levy, GA | 1 |
| Raghavan, K | 1 |
| Dedeepiya, VD | 1 |
| Yamamoto, N | 1 |
| Srinivasan, S | 1 |
| Ranganathan, N | 1 |
| Iwasaki, M | 1 |
| Senthilkumar, R | 1 |
| Abraham, SJK | 1 |
| Liu, CS | 2 |
| Hu, YX | 2 |
| Luo, ZY | 2 |
| Qiu, CW | 2 |
| Deng, XH | 2 |
| Chen, FL | 2 |
| Yan, XL | 2 |
| Liu, XC | 2 |
| Zhang, YN | 2 |
| Du, TT | 2 |
| Ai, Q | 2 |
| Gao, X | 3 |
| Yang, JL | 2 |
| Bao, L | 2 |
| Li, LQ | 2 |
| Morris, JP | 1 |
| Yashinskie, JJ | 1 |
| Koche, R | 1 |
| Chandwani, R | 1 |
| Tian, S | 1 |
| Chen, CC | 1 |
| Baslan, T | 1 |
| Marinkovic, ZS | 1 |
| Sánchez-Rivera, FJ | 1 |
| Leach, SD | 1 |
| Carmona-Fontaine, C | 1 |
| Thompson, CB | 1 |
| Finley, LWS | 1 |
| Lowe, SW | 1 |
| Li, X | 12 |
| Mao, M | 1 |
| Zhang, Y | 7 |
| Yu, K | 2 |
| Zhu, W | 2 |
| Zhang, M | 5 |
| Yu, J | 1 |
| Wang, Q | 3 |
| Zhang, J | 5 |
| Cui, Y | 2 |
| Pan, X | 1 |
| Sun, H | 2 |
| Braun, MM | 1 |
| Damjanac, T | 1 |
| Chen, C | 1 |
| Hu, J | 3 |
| Maher, LJ | 1 |
| Galla, S | 1 |
| Chakraborty, S | 1 |
| Cheng, X | 1 |
| Yeo, JY | 1 |
| Mell, B | 1 |
| Chiu, N | 1 |
| Wenceslau, CF | 1 |
| Vijay-Kumar, M | 1 |
| Joe, B | 1 |
| Isogai, N | 1 |
| Shiono, Y | 1 |
| Kuramoto, T | 1 |
| Yoshioka, K | 1 |
| Ishihama, H | 1 |
| Funao, H | 1 |
| Nakamura, M | 1 |
| Matsumoto, M | 2 |
| Ishii, K | 1 |
| Karimi, M | 1 |
| Petkova, V | 1 |
| Asara, JM | 2 |
| Griffin, MJ | 1 |
| Sellke, FW | 1 |
| Bishop, AR | 1 |
| Alexandrov, BS | 1 |
| Usheva, A | 1 |
| Pala, L | 1 |
| Kula-Alwar, D | 1 |
| Mulvey, JF | 2 |
| Luping, D | 1 |
| Beach, TE | 2 |
| Booty, LM | 1 |
| Logan, A | 3 |
| Sauchanka, V | 1 |
| Caldwell, ST | 1 |
| Robb, EL | 2 |
| Xu, Z | 2 |
| Hartley, RC | 2 |
| Huang, MM | 1 |
| Young, T | 1 |
| Tronci, L | 1 |
| Nikitopoulou, E | 1 |
| Ascione, R | 1 |
| Hadjihambi, A | 1 |
| Shattock, MJ | 2 |
| Pellerin, L | 1 |
| Frezza, C | 3 |
| Aksentijević, D | 2 |
| Banerjee, A | 3 |
| Herring, CA | 1 |
| Chen, B | 2 |
| Kim, H | 2 |
| Simmons, AJ | 1 |
| Southard-Smith, AN | 1 |
| Allaman, MM | 1 |
| White, JR | 1 |
| Macedonia, MC | 1 |
| Mckinley, ET | 1 |
| Ramirez-Solano, MA | 1 |
| Scoville, EA | 1 |
| Liu, Q | 2 |
| Wilson, KT | 1 |
| Coffey, RJ | 1 |
| Washington, MK | 1 |
| Goettel, JA | 1 |
| Lau, KS | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 2 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Song, J | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Li, Y | 6 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
| Wang, Y | 2 |
| Meng, J | 1 |
| Chen, G | 2 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
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| Liu, X | 1 |
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| Li, J | 7 |
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| Zhuang, T | 1 |
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| Xie, X | 1 |
| Zhao, Q | 1 |
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| Wu, X | 1 |
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| Yang, X | 2 |
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| Huang, H | 1 |
| Wei, Y | 3 |
| Gao, Y | 2 |
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| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
| Paeng, JC | 1 |
| Park, IK | 1 |
| Kang, CH | 1 |
| Cheon, GJ | 1 |
| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
| Pajuelo-Lozano, N | 1 |
| Alcalá, S | 1 |
| Sainz, B | 1 |
| Perona, R | 1 |
| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
| Richter, C | 1 |
| Edelhäuser, BAH | 1 |
| Engelmann, D | 1 |
| Brenmoehl, J | 1 |
| Söhnchen, C | 1 |
| Murr, N | 1 |
| Alpers, M | 1 |
| Singh, KP | 1 |
| Wolkenhauer, O | 1 |
| Heckl, D | 1 |
| Spitschak, A | 1 |
| Pützer, BM | 1 |
| Liao, Y | 1 |
| Cheng, J | 1 |
| Kong, X | 1 |
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2 reviews available for succinic acid and Disease Models, Animal
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
[Succinic semialdehyde dehydrogenase deficiency: an inheritable neurometabolic disease].
Topics: Amino Acid Metabolism, Inborn Errors; Aminobutyrates; Animals; Brain Diseases, Metabolic, Inborn; Da | 2013 |
1 trial available for succinic acid and Disease Models, Animal
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
79 other studies available for succinic acid and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
Topics: Animals; Case-Control Studies; Cell Communication; Cells, Cultured; Colitis; Colon; Cytotoxicity, Im | 2021 |
Comparative Study of Functional Changes in Heart Mitochondria in Two Modes of Epinephrine Exposure Modeling Myocardial Injury in Rats.
Topics: Adenosine Triphosphate; Animals; Calcium; Cardiomyopathies; Cations, Divalent; Disease Models, Anima | 2021 |
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Autopsy; Brain; Cas | 2022 |
Dimethyl malonate slows succinate accumulation and preserves cardiac function in a swine model of hemorrhagic shock.
Topics: Animals; Calcium; Disease Models, Animal; Humans; Lactates; Malonates; Resuscitation; Shock, Hemorrh | 2022 |
Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; Energy Metabolism; Hypoxia; Ischemia; Lactates; Mice; Myocytes, Car | 2022 |
Two unique biological response-modifier glucans beneficially regulating gut microbiota and faecal metabolome in a non-alcoholic steatohepatitis animal model, with potential applications in human health and disease.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Firmicutes; Fructose; Gastrointestinal Mi | 2022 |
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
Succinate aggravates intestinal injury in mice with necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Humans; Infant, Newbo | 2022 |
Succinate aggravates intestinal injury in mice with necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Humans; Infant, Newbo | 2022 |
Succinate aggravates intestinal injury in mice with necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Humans; Infant, Newbo | 2022 |
Succinate aggravates intestinal injury in mice with necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Enterocolitis, Necrotizing; Humans; Infant, Newbo | 2022 |
α-Ketoglutarate links p53 to cell fate during tumour suppression.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Differentiation; Cell Line, Tumor; Chromatin Assembly an | 2019 |
Succinate Modulates Intestinal Barrier Function and Inflammation Response in Pigs.
Topics: Animals; Cell Line; Disease Models, Animal; Electric Impedance; Gene Expression Regulation; Inflamma | 2019 |
Succinate accumulation induces mitochondrial reactive oxygen species generation and promotes status epilepticus in the kainic acid rat model.
Topics: Animals; Disease Models, Animal; Electroencephalography; Kainic Acid; Male; Mitochondria; Mitophagy; | 2020 |
Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor.
Topics: Adrenal Gland Neoplasms; Amino Acids, Dicarboxylic; Animals; Animals, Genetically Modified; Caenorha | 2019 |
Exposure to Amoxicillin in Early Life Is Associated With Changes in Gut Microbiota and Reduction in Blood Pressure: Findings From a Study on Rat Dams and Offspring.
Topics: Age Factors; Amoxicillin; Animals; Anti-Bacterial Agents; Blood Pressure; Disease Models, Animal; Fe | 2020 |
Potential osteomyelitis biomarkers identified by plasma metabolome analysis in mice.
Topics: Animals; Biomarkers; Carnitine; Citric Acid Cycle; Disease Models, Animal; Fatty Acids; Ketoglutaric | 2020 |
Metabolomics and the pig model reveal aberrant cardiac energy metabolism in metabolic syndrome.
Topics: Animals; Biomarkers; Citric Acid Cycle; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; G | 2020 |
Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo.
Topics: Animals; Cardiotonic Agents; Cell Line; Disease Models, Animal; Esters; Female; Humans; Male; Malona | 2022 |
Mechanism of succinate efflux upon reperfusion of the ischaemic heart.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Female; Isolated Heart Preparation; Male; Metabolo | 2021 |
Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Chemoreceptor Cells; Crohn Disease; Disease M | 2020 |
Host succinate is an activation signal for
Topics: Animals; Bacterial Proteins; Cell Survival; Dicarboxylic Acid Transporters; Disease Models, Animal; | 2021 |
Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.
Topics: Animals; Cardiolipins; Cardiomegaly; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Digly | 2021 |
Abnormal composition of microbiota in the gut and skin of imiquimod-treated mice.
Topics: Animals; Dermatitis; Disease Models, Animal; Female; Gastrointestinal Microbiome; Imiquimod; Lactic | 2021 |
Western Diet Decreases the Liver Mitochondrial Oxidative Flux of Succinate: Insight from a Murine NAFLD Model.
Topics: Animals; Apoptosis; Biomarkers; Cell Respiration; Diet, Western; Disease Models, Animal; Disease Sus | 2021 |
A transepithelial pathway delivers succinate to macrophages, thus perpetuating their pro-inflammatory metabolic state.
Topics: Animals; Bacteria; Disease Models, Animal; Epithelial Cells; Feces; Gastrointestinal Microbiome; Gen | 2021 |
Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice.
Topics: 3-Hydroxybutyric Acid; Adrenergic beta-Antagonists; Animals; Brain; Brain Ischemia; Citric Acid; Die | 2017 |
Optimization of mitochondrial isolation techniques for intraspinal transplantation procedures.
Topics: Animals; Cell Fractionation; Disease Models, Animal; Feasibility Studies; Female; Green Fluorescent | 2017 |
All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured patients.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Disease Models, Animal; Gas Chromatograph | 2018 |
Activation of Vibrio cholerae quorum sensing promotes survival of an arthropod host.
Topics: Adipose Tissue; Animals; Arthropods; Bacterial Proteins; Biofilms; Disease Models, Animal; Drosophil | 2018 |
Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model.
Topics: Animals; Cerebellum; Disease Models, Animal; Mice; Mice, Transgenic; Mitochondria; Oxidative Phospho | 2017 |
The Role of Succinate in Regulation of Immediate HIF-1α Expression in Hypoxia.
Topics: Adaptation, Physiological; Altitude Sickness; Animals; Cerebral Cortex; Citric Acid Cycle; Disease M | 2018 |
Sensors of Succinate: Neural Stem Cell Grafts Fight Neuroinflammation.
Topics: Animals; Disease Models, Animal; Macrophages; Mice; Neural Stem Cells; Succinic Acid | 2018 |
Deep Vein Thrombosis Exhibits Characteristic Serum and Vein Wall Metabolic Phenotypes in the Inferior Vena Cava Ligation Mouse Model.
Topics: Acetylcarnitine; Adenosine; Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Ene | 2018 |
Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Humans; Hypoxia-Ind | 2018 |
Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Energy Metabolism; Ischemic Preconditioning, | 2018 |
Succinate receptor mediates intestinal inflammation and fibrosis.
Topics: Adolescent; Adult; Animals; Cells, Cultured; Colitis; Crohn Disease; Disease Models, Animal; Female; | 2019 |
High drug payload nanoparticles formed from dexamethasone-peptide conjugates for the treatment of endotoxin-induced uveitis in rabbit.
Topics: Animals; Anti-Inflammatory Agents; Cell Death; Dexamethasone; Disease Models, Animal; Drug Liberatio | 2019 |
G-protein-coupled receptor 91 and succinate are key contributors in neonatal postcerebral hypoxia-ischemia recovery.
Topics: Angiogenic Proteins; Animals; Animals, Newborn; Astrocytes; Cell Line; Cerebral Cortex; Cerebral Inf | 2014 |
[The influence of dietary omega-3 polyunsaturated fatty acids on functional parameters of myocardial mitochondria during isoproterenol-induced heart injury].
Topics: Administration, Oral; Animals; Calcium; Disease Models, Animal; Fatty Acids, Omega-3; Isoproterenol; | 2014 |
Cyclic stretch and hypertension increase retinal succinate: potential mechanisms for exacerbation of ocular neovascularization by mechanical stress.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linke | 2014 |
In vivo anti-Trypanosoma cruzi activity of hydro-ethanolic extract and isolated active principles from Aristeguietia glutinosa and mechanism of action studies.
Topics: Animals; Antiprotozoal Agents; Asteraceae; Chagas Disease; Disease Models, Animal; Diterpenes; Drug | 2014 |
Triggering the succinate receptor GPR91 enhances pressure overload-induced right ventricular hypertrophy.
Topics: Animals; Atrial Natriuretic Factor; Cells, Cultured; Disease Models, Animal; Hypertension, Pulmonary | 2014 |
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.
Topics: Adenosine Monophosphate; Animals; Aspartic Acid; Citric Acid Cycle; Disease Models, Animal; Electron | 2014 |
Nrf2-ARE activator carnosic acid decreases mitochondrial dysfunction, oxidative damage and neuronal cytoskeletal degradation following traumatic brain injury in mice.
Topics: Abietanes; Adenosine Diphosphate; Aldehydes; Analysis of Variance; Animals; Antioxidants; Brain; Bra | 2015 |
Animal Models of Depression and Drug Delivery with Food as an Effective Dosing Method: Evidences from Studies with Celecoxib and Dicholine Succinate.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Celecoxib; Depressive Disorder; Disease Models, An | 2015 |
[Antidepressant effect of 3-oxypyridine and succinic acid derivatives (experimental study)].
Topics: Animals; Behavior, Animal; Depressive Disorder; Disease Models, Animal; Female; Male; Meglumine; Pic | 2015 |
Succinate Accumulation and Ischemia-Reperfusion Injury: Of Mice but Not Men, a Study in Renal Ischemia-Reperfusion.
Topics: Animals; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidative Str | 2016 |
Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock.
Topics: Animals; Brain; Disease Models, Animal; Glutamine; Liver; Lung; Myocardium; Rats; Rats, Sprague-Dawl | 2016 |
Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function.
Topics: Animals; Behavior, Animal; Cerebellum; Chromatography, High Pressure Liquid; Dendrites; Disease Mode | 2017 |
Neuroprotection in diet-induced ketotic rat brain after focal ischemia.
Topics: Animals; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Diet, Ketogenic; Disease Models, Anim | 2008 |
Protective effect of aspartate and glutamate on cardiac mitochondrial function during myocardial infarction in experimental rats.
Topics: Animals; Aspartic Acid; Disease Models, Animal; Enzyme Activation; Glutamic Acid; Glutathione; Gluta | 2008 |
Metabonomic characterization of the 3-nitropropionic acid rat model of Huntington's disease.
Topics: Animals; Behavior, Animal; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Choline; Corpus Striatum; | 2009 |
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
Topics: Analysis of Variance; Animals; Biomarkers; Blotting, Western; Disease Models, Animal; DNA, Complemen | 2009 |
Prebiotic treatment in experimental colitis reduces the risk of colitic cancer.
Topics: Adenoma; Animals; beta-Glucosidase; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Colonosco | 2011 |
Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
Topics: Adult; Aged; Animals; Biomarkers, Tumor; Carcinoma, Renal Cell; Disease Models, Animal; Female; Fuma | 2011 |
Early hyperglycemia following alloxan administration in vivo is not associated with altered hepatic mitochondrial function: acceptable model for type 1 diabetes?
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease | 2011 |
[Cerebroprotective effect of 3-oxypyridine and succinic acid derivatives in acute phase of alloxan-induced diabetes mellitus in rats].
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Anim | 2011 |
Idebenone-induced recovery of glycerol-3-phosphate and succinate oxidation inhibited by digitonin.
Topics: Animals; Cytochromes c; Digitonin; Disease Models, Animal; Dose-Response Relationship, Drug; Glycero | 2012 |
(-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Biomarkers; Calcium; Catechin; Citric Acid Cycle; Cre | 2013 |
Roles of mucosal bacteria and succinic acid in colitis caused by dextran sulfate sodium in mice.
Topics: Acetates; Animals; Bacteroidaceae; Bacteroides; Butyric Acid; Carboxylic Acids; Cecum; Colitis; Coli | 2000 |
Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis.
Topics: Adenosine Triphosphatases; Animals; Blotting, Western; Cardiomegaly; Cytochromes; Disease Models, An | 2003 |
Creatine protects against the convulsive behavior and lactate production elicited by the intrastriatal injection of methylmalonate.
Topics: Animals; Behavior, Animal; Corpus Striatum; Creatine; Disease Models, Animal; Dizocilpine Maleate; D | 2003 |
[Tricarboxylic acid cycle in energy metabolism and antioxidant cell defense in acute hypoxia].
Topics: Acute Disease; Animals; Antioxidants; Catalase; Cholinergic Antagonists; Citric Acid Cycle; Disease | 2003 |
3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy.
Topics: Acute Disease; Animals; Behavior, Animal; Body Weight; Brain; Choline; Chronic Disease; Disease Mode | 2004 |
Investigations into biochemical changes of genetic hypertensive rats using 1H nuclear magnetic resonance-based metabonomics.
Topics: Animals; Citric Acid; Creatine; Creatinine; Dimethylamines; Disease Models, Animal; Hypertension; Ke | 2005 |
Creatine prevents behavioral alterations caused by methylmalonic acid administration into the hippocampus of rats in the open field task.
Topics: Animals; Avoidance Learning; Brain Diseases, Metabolic, Inborn; Creatine; Disease Models, Animal; En | 2006 |
Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infarcted rats.
Topics: Animals; Antioxidants; Blood Glucose; Disease Models, Animal; Energy Metabolism; Glutathione; Isopro | 2006 |
Role of the L-citrulline/L-arginine cycle in iNANC nerve-mediated nitric oxide production and airway smooth muscle relaxation in allergic asthma.
Topics: Allergens; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Asthma; Citrullin | 2006 |
Biochemical changes in selenite cataract model measured by high-resolution MAS H NMR spectroscopy.
Topics: Amino Acids; Animals; Animals, Newborn; Cataract; Crystallins; Disease Models, Animal; Glutathione; | 2006 |
Prophylaxis of encephalopathies and risk factors of atherogenesis development in the postresuscitation period in rats by means of succinic acid.
Topics: Animals; Arteriosclerosis; Behavior, Animal; Brain Ischemia; Cardiopulmonary Resuscitation; Disease | 1997 |
Altered mitochondrial function in canine ceroid-lipofuscinosis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Disease Models, Animal; Dogs; Glutamic Acid; | 1998 |
Metabolism of [1,3-(13)C]glycerol-1,2,3-tris(methylsuccinate) and glycerol-1,2,3-tris(methyl[2,3-(13)C]succinate) in hepatocytes from Goto-Kakizaki rats.
Topics: Animals; Carbon Isotopes; Cells, Cultured; Chloride Channels; Diabetes Mellitus, Type 2; Disease Mod | 1999 |
Intestinal metabolism after ischemia-reperfusion.
Topics: Amino Acids; Analysis of Variance; Animals; Disease Models, Animal; Glucose; Intestine, Small; Ische | 2000 |
The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Disease M | 2000 |
Prolongation of survival time by infusion of succinic acid dimethyl ester in a caecal ligation and perforation model of sepsis.
Topics: Animals; Cecum; Disease Models, Animal; Female; Ligation; Peritonitis; Punctures; Rats; Rats, Wistar | 2000 |
Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Cerebral Cortex; Chromium; Creatine Kinas | 2002 |
Highly water-soluble matrix metalloproteinases inhibitors and their effects in a rat adjuvant-induced arthritis model.
Topics: ADAM Proteins; ADAM17 Protein; Amides; Animals; Arthritis; Disease Models, Animal; Enzyme Inhibitors | 2002 |
Succinylacetone effects on renal tubular phosphate metabolism: a model for experimental renal Fanconi syndrome.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Disease Models, Animal; Fanconi Syndrome; Glutamat | 1991 |
[Comparative evaluation of the effects of crystalloid solutions containing sodium lactate and sodium succinate on the hemodynamic indicators in different types of hemorrhage].
Topics: Animals; Crystalloid Solutions; Disease Models, Animal; Female; Hemodynamics; Hemorrhage; Isotonic S | 1991 |
[Effect of sodium succinate on the development of experimental silicosis].
Topics: Animals; Disease Models, Animal; Female; Quartz; Rats; Silicosis; Succinates; Succinic Acid | 1990 |