succinic acid has been researched along with Diabetic Nephropathies in 4 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance to prevent its development." | 1.39 | GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy. ( Aa, J; Cao, B; Ge, Y; Li, M; Liu, L; Liu, Z; Qin, W; Shi, J; Wang, G; Wang, X; Yu, X; Zha, W; Zhao, C; Zheng, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Zhang, X | 1 |
| Yao, H | 1 |
| Chen, X | 1 |
| Shang, L | 1 |
| Li, P | 1 |
| Cui, X | 1 |
| Zeng, J | 1 |
| Li, M | 1 |
| Wang, X | 2 |
| Aa, J | 1 |
| Qin, W | 1 |
| Zha, W | 1 |
| Ge, Y | 1 |
| Liu, L | 1 |
| Zheng, T | 1 |
| Cao, B | 1 |
| Shi, J | 1 |
| Zhao, C | 1 |
| Yu, X | 1 |
| Wang, G | 1 |
| Liu, Z | 1 |
| Peti-Peterdi, J | 1 |
| Rosca, MG | 1 |
| Monnier, VM | 1 |
| Szweda, LI | 1 |
| Weiss, MF | 1 |
1 review available for succinic acid and Diabetic Nephropathies
| Article | Year |
|---|---|
High glucose and renin release: the role of succinate and GPR91.
Topics: Diabetic Nephropathies; Glomerular Filtration Rate; Humans; Hyperglycemia; Kidney Tubules, Distal; R | 2010 |
3 other studies available for succinic acid and Diabetic Nephropathies
| Article | Year |
|---|---|
Peroxisome-generated succinate induces lipid accumulation and oxidative stress in the kidneys of diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fatty Acids; Female; Humans; Kidne | 2022 |
GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy.
Topics: 3-Hydroxybutyric Acid; Albuminuria; Allantoin; Amino Acids; Animals; Arachidonic Acid; Biomarkers; C | 2013 |
Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal.
Topics: Adenosine Diphosphate; Animals; Diabetic Nephropathies; Electron Transport; Kidney; Mitochondria; Mi | 2002 |