Page last updated: 2024-10-20

succinic acid and Cystic Fibrosis

succinic acid has been researched along with Cystic Fibrosis in 3 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
"Pseudomonas aeruginosa NM48, a non-mucoid derivative of an alginate-producing strain isolated from a cystic fibrosis patient, was grown in batch culture with glycerol, glucose or succinate as carbon source, and in continuous culture (D 0."3.69The effect of nutrient limitation on glycerol uptake and metabolism in continuous cultures of Pseudomonas aeruginosa. ( Greenwood, JA; Jones, CW; Williams, SG, 1994)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Tomlinson, KL1
Lung, TWF1
Dach, F1
Annavajhala, MK1
Gabryszewski, SJ1
Groves, RA1
Drikic, M1
Francoeur, NJ1
Sridhar, SH1
Smith, ML1
Khanal, S1
Britto, CJ1
Sebra, R1
Lewis, I1
Uhlemann, AC1
Kahl, BC1
Prince, AS1
Riquelme, SA1
D'Argenio, DA1
Wu, M1
Hoffman, LR1
Kulasekara, HD1
Déziel, E1
Smith, EE1
Nguyen, H1
Ernst, RK1
Larson Freeman, TJ1
Spencer, DH1
Brittnacher, M1
Hayden, HS1
Selgrade, S1
Klausen, M1
Goodlett, DR1
Burns, JL1
Ramsey, BW1
Miller, SI1
Williams, SG1
Greenwood, JA1
Jones, CW1

Other Studies

3 other studies available for succinic acid and Cystic Fibrosis

ArticleYear
Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation.
    Nature communications, 2021, 03-03, Volume: 12, Issue:1

    Topics: Adult; Animals; Biofilms; Bronchoalveolar Lavage Fluid; Carbohydrate Metabolism; Cystic Fibrosis; Ge

2021
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients.
    Molecular microbiology, 2007, Volume: 64, Issue:2

    Topics: Adaptation, Biological; Alleles; Amides; Amino Acid Sequence; Amino Acids; Bacterial Proteins; beta-

2007
The effect of nutrient limitation on glycerol uptake and metabolism in continuous cultures of Pseudomonas aeruginosa.
    Microbiology (Reading, England), 1994, Volume: 140 ( Pt 11)

    Topics: Adaptation, Biological; Alginates; Amino Acid Sequence; Bacterial Proteins; Cell Membrane; Culture M

1994