succinic acid has been researched along with Colonic Neoplasms in 3 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is an increased risk of colon cancer associated with inflammatory bowel disease (IBD)." | 1.91 | Refined fiber inulin promotes inflammation-associated colon tumorigenesis by modulating microbial succinate production. ( Castro, R; Hao, F; Neupane, R; Patterson, AD; Paudel, D; Prabhu, KS; Singh, V; Tian, S; Tiwari, AK, 2023) |
| "With ulcerative colitis (UC)-associated tumorigenesis, p53 gene alteration is considered to be a key event." | 1.33 | Disruption of the p53-p53r2 DNA repair system in ulcerative colitis contributes to colon tumorigenesis. ( Haga, S; Mikami, T; Numata, Y; Ogawa, T; Ohkusa, T; Okayasu, I; Yamashita, K; Yoshida, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, S | 1 |
| Paudel, D | 1 |
| Hao, F | 1 |
| Neupane, R | 1 |
| Castro, R | 1 |
| Patterson, AD | 1 |
| Tiwari, AK | 1 |
| Prabhu, KS | 1 |
| Singh, V | 1 |
| Komiyama, Y | 1 |
| Mitsuyama, K | 1 |
| Masuda, J | 1 |
| Yamasaki, H | 1 |
| Takedatsu, H | 1 |
| Andoh, A | 1 |
| Tsuruta, O | 1 |
| Fukuda, M | 1 |
| Kanauchi, O | 1 |
| Yoshida, T | 1 |
| Haga, S | 1 |
| Numata, Y | 1 |
| Yamashita, K | 1 |
| Mikami, T | 1 |
| Ogawa, T | 1 |
| Ohkusa, T | 1 |
| Okayasu, I | 1 |
3 other studies available for succinic acid and Colonic Neoplasms
| Article | Year |
|---|---|
Refined fiber inulin promotes inflammation-associated colon tumorigenesis by modulating microbial succinate production.
Topics: Animals; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Colorectal Neo | 2023 |
Prebiotic treatment in experimental colitis reduces the risk of colitic cancer.
Topics: Adenoma; Animals; beta-Glucosidase; Cell Proliferation; Colitis; Colon; Colonic Neoplasms; Colonosco | 2011 |
Disruption of the p53-p53r2 DNA repair system in ulcerative colitis contributes to colon tumorigenesis.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Butyrates; Cell Cycle; Cell Cycle Proteins | 2006 |