succinic acid has been researched along with Colitis Gravis in 7 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our previous studies showed a low oral bioavailability and a predominant distribution of major XLP ingredients in the gut." | 1.91 | Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats. ( Chen, FL; Deng, XH; Hu, YX; Liu, CS; Luo, ZY; Qiu, CW, 2023) |
| "With ulcerative colitis (UC)-associated tumorigenesis, p53 gene alteration is considered to be a key event." | 1.33 | Disruption of the p53-p53r2 DNA repair system in ulcerative colitis contributes to colon tumorigenesis. ( Haga, S; Mikami, T; Numata, Y; Ogawa, T; Ohkusa, T; Okayasu, I; Yamashita, K; Yoshida, T, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, CS | 2 |
| Hu, YX | 2 |
| Luo, ZY | 2 |
| Qiu, CW | 2 |
| Deng, XH | 2 |
| Chen, FL | 2 |
| Qiao, X | 1 |
| Gao, Q | 1 |
| Yang, L | 1 |
| Wang, X | 1 |
| Wang, Z | 1 |
| Li, Z | 1 |
| Xu, J | 1 |
| Xue, C | 1 |
| Zhou, H | 1 |
| Ikeuchi-Takahashi, Y | 1 |
| Hattori, Y | 1 |
| Onishi, H | 1 |
| Meng, X | 1 |
| Dunsmore, G | 1 |
| Koleva, P | 1 |
| Elloumi, Y | 1 |
| Wu, RY | 1 |
| Sutton, RT | 1 |
| Ambrosio, L | 1 |
| Hotte, N | 1 |
| Nguyen, V | 1 |
| Madsen, KL | 1 |
| Dieleman, LA | 1 |
| Chen, H | 1 |
| Huang, V | 1 |
| Elahi, S | 1 |
| Sitkin, SI | 1 |
| Tkachenko, EI | 1 |
| Vakhitov, TIa | 1 |
| Oreshko, LS | 1 |
| Zhigalova, TN | 1 |
| Ariake, K | 1 |
| Ohkusa, T | 2 |
| Sakurazawa, T | 1 |
| Kumagai, J | 1 |
| Eishi, Y | 1 |
| Hoshi, S | 1 |
| Yajima, T | 1 |
| Yoshida, T | 1 |
| Haga, S | 1 |
| Numata, Y | 1 |
| Yamashita, K | 1 |
| Mikami, T | 1 |
| Ogawa, T | 1 |
| Okayasu, I | 1 |
1 trial available for succinic acid and Colitis Gravis
| Article | Year |
|---|---|
[Serum metabolome by gas chromatography-mass spectrometry (GC-MS) in patients with ulcerative colitis and celiac disease].
Topics: Adolescent; Adult; Carboxylic Acids; Celiac Disease; Colitis, Ulcerative; Combined Modality Therapy; | 2013 |
6 other studies available for succinic acid and Colitis Gravis
| Article | Year |
|---|---|
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
Xianglian pill modulates gut microbial production of succinate and induces regulatory T cells to alleviate ulcerative colitis in rats.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointesti | 2023 |
In-Depth Analysis of the Mechanism of Astaxanthin Succinate Diester in Reducing Ulcerative Colitis in C57BL/6J Mice Based on Microbiota Informatics.
Topics: Animals; Colitis, Ulcerative; Mice; Mice, Inbred C57BL; Microbiota; RNA, Ribosomal, 16S; Succinates; | 2023 |
Nanogels of a Succinylated Glycol Chitosan-Succinyl Prednisolone Conjugate: Release Behavior, Gastrointestinal Distribution, and Systemic Absorption.
Topics: Animals; Anti-Inflammatory Agents; Chitosan; Colitis, Ulcerative; Drug Carriers; Drug Delivery Syste | 2020 |
The Profile of Human Milk Metabolome, Cytokines, and Antibodies in Inflammatory Bowel Diseases Versus Healthy Mothers, and Potential Impact on the Newborn.
Topics: Aminobutyrates; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Case-Control Studies; | 2019 |
Roles of mucosal bacteria and succinic acid in colitis caused by dextran sulfate sodium in mice.
Topics: Acetates; Animals; Bacteroidaceae; Bacteroides; Butyric Acid; Carboxylic Acids; Cecum; Colitis; Coli | 2000 |
Disruption of the p53-p53r2 DNA repair system in ulcerative colitis contributes to colon tumorigenesis.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Butyrates; Cell Cycle; Cell Cycle Proteins | 2006 |