succinic acid has been researched along with Colitis, Granulomatous in 6 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pathogenesis of Crohn's disease-associated fibrostenosis and fistulas imply the epithelial-to-mesenchymal transition (EMT) process." | 1.56 | Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development. ( Alós, R; Barrachina, MD; Bauset, C; Calatayud, S; Coll, S; Cosín-Roger, J; Esplugues, JV; Gisbert-Ferrándiz, L; Mamie, C; Navarro, F; Ortiz-Masiá, D; Scharl, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Monfort-Ferré, D | 1 |
| Caro, A | 1 |
| Menacho, M | 1 |
| Martí, M | 1 |
| Espina, B | 1 |
| Boronat-Toscano, A | 1 |
| Nuñez-Roa, C | 1 |
| Seco, J | 1 |
| Bautista, M | 1 |
| Espín, E | 1 |
| Megía, A | 1 |
| Vendrell, J | 1 |
| Fernández-Veledo, S | 1 |
| Serena, C | 1 |
| Ortiz-Masiá, D | 2 |
| Gisbert-Ferrándiz, L | 2 |
| Bauset, C | 1 |
| Coll, S | 1 |
| Mamie, C | 1 |
| Scharl, M | 1 |
| Esplugues, JV | 2 |
| Alós, R | 2 |
| Navarro, F | 2 |
| Cosín-Roger, J | 2 |
| Barrachina, MD | 2 |
| Calatayud, S | 2 |
| Banerjee, A | 1 |
| Herring, CA | 1 |
| Chen, B | 1 |
| Kim, H | 1 |
| Simmons, AJ | 1 |
| Southard-Smith, AN | 1 |
| Allaman, MM | 1 |
| White, JR | 1 |
| Macedonia, MC | 1 |
| Mckinley, ET | 1 |
| Ramirez-Solano, MA | 1 |
| Scoville, EA | 1 |
| Liu, Q | 1 |
| Wilson, KT | 1 |
| Coffey, RJ | 1 |
| Washington, MK | 1 |
| Goettel, JA | 1 |
| Lau, KS | 1 |
| Rosen, MJ | 1 |
| Macias-Ceja, DC | 1 |
| Salvador, P | 1 |
| Hernández, C | 1 |
| Hausmann, M | 1 |
| Rogler, G | 1 |
| Hinojosa, J | 1 |
| Meng, X | 1 |
| Dunsmore, G | 1 |
| Koleva, P | 1 |
| Elloumi, Y | 1 |
| Wu, RY | 1 |
| Sutton, RT | 1 |
| Ambrosio, L | 1 |
| Hotte, N | 1 |
| Nguyen, V | 1 |
| Madsen, KL | 1 |
| Dieleman, LA | 1 |
| Chen, H | 1 |
| Huang, V | 1 |
| Elahi, S | 1 |
6 other studies available for succinic acid and Colitis, Granulomatous
| Article | Year |
|---|---|
The Gut Microbiota Metabolite Succinate Promotes Adipose Tissue Browning in Crohn's Disease.
Topics: Adipose Tissue; Adipose Tissue, White; Crohn Disease; Gastrointestinal Microbiome; Humans; Succinic | 2022 |
Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development.
Topics: Animals; Cadherins; Crohn Disease; Epithelial Cells; Fibrosis; Fistula; Humans; Inflammation; Intest | 2020 |
Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Chemoreceptor Cells; Crohn Disease; Disease M | 2020 |
Could a Small Population of Epithelial Cells Get "Tuft" With Crohn's Disease?
Topics: Crohn Disease; Epithelial Cells; Humans; Inflammation; Intestinal Mucosa; Succinic Acid | 2020 |
Succinate receptor mediates intestinal inflammation and fibrosis.
Topics: Adolescent; Adult; Animals; Cells, Cultured; Colitis; Crohn Disease; Disease Models, Animal; Female; | 2019 |
The Profile of Human Milk Metabolome, Cytokines, and Antibodies in Inflammatory Bowel Diseases Versus Healthy Mothers, and Potential Impact on the Newborn.
Topics: Aminobutyrates; Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Case-Control Studies; | 2019 |