succinic acid has been researched along with Cardiac Hypertrophy in 3 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mice with juvenile visceral steatosis (JVS) develop remarkable cardiac hypertrophy and exhibit an increased number of mitochondria in their heart." | 1.32 | Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis. ( Arakaki, N; Higuti, T; Himeda, T; Kuwajima, M; Morokami, K; Shibata, H; Suenaga, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chambers, KT | 1 |
| Cooper, MA | 1 |
| Swearingen, AR | 1 |
| Brookheart, RT | 1 |
| Schweitzer, GG | 1 |
| Weinheimer, CJ | 1 |
| Kovacs, A | 1 |
| Koves, TR | 1 |
| Muoio, DM | 1 |
| McCommis, KS | 1 |
| Finck, BN | 1 |
| Hershberger, KA | 1 |
| Abraham, DM | 1 |
| Liu, J | 1 |
| Locasale, JW | 1 |
| Grimsrud, PA | 1 |
| Hirschey, MD | 1 |
| Suenaga, M | 1 |
| Arakaki, N | 1 |
| Morokami, K | 1 |
| Himeda, T | 1 |
| Shibata, H | 1 |
| Kuwajima, M | 1 |
| Higuti, T | 1 |
3 other studies available for succinic acid and Cardiac Hypertrophy
| Article | Year |
|---|---|
Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.
Topics: Animals; Cardiolipins; Cardiomegaly; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Digly | 2021 |
Ablation of
Topics: Animals; Cardiomegaly; Female; Gene Expression Regulation; Heart; Male; Metabolic Networks and Pathw | 2018 |
Functional disorders of the oxidative phosphorylation system in the heart mitochondria of mice with juvenile visceral steatosis.
Topics: Adenosine Triphosphatases; Animals; Blotting, Western; Cardiomegaly; Cytochromes; Disease Models, An | 2003 |