succinic acid has been researched along with Brain Edema in 1 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuroprotective properties of ketosis may be related to the upregulation of hypoxia inducible factor (HIF)-1alpha, a primary constituent associated with hypoxic angiogenesis and a regulator of neuroprotective responses." | 1.35 | Neuroprotection in diet-induced ketotic rat brain after focal ischemia. ( Emancipator, DS; LaManna, JC; Lust, WD; Puchowicz, MA; Pundik, S; Valerio, J; Xu, K; Zechel, JL, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Puchowicz, MA | 1 |
| Zechel, JL | 1 |
| Valerio, J | 1 |
| Emancipator, DS | 1 |
| Xu, K | 1 |
| Pundik, S | 1 |
| LaManna, JC | 1 |
| Lust, WD | 1 |
1 other study available for succinic acid and Brain Edema
| Article | Year |
|---|---|
Neuroprotection in diet-induced ketotic rat brain after focal ischemia.
Topics: Animals; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Diet, Ketogenic; Disease Models, Anim | 2008 |