succinic acid has been researched along with Blood Poisoning in 9 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis is a life-threatening disease characterized by a defensive response to damage." | 6.82 | Role of succinic acid in the regulation of sepsis. ( Chen, Q; Liu, H; Xia, L; Zhang, H; Zhang, X, 2022) |
| "The development and reversal of the adult respiratory distress syndrome (ARDS) was followed and resulted in data on 304 of the 382 randomized patients." | 6.66 | Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome. ( Bone, RC; Clemmer, TP; Fisher, CJ; Metz, CA; Slotman, GJ, 1987) |
| "Sepsis is a life-threatening disease characterized by a defensive response to damage." | 2.82 | Role of succinic acid in the regulation of sepsis. ( Chen, Q; Liu, H; Xia, L; Zhang, H; Zhang, X, 2022) |
| "The development and reversal of the adult respiratory distress syndrome (ARDS) was followed and resulted in data on 304 of the 382 randomized patients." | 2.66 | Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome. ( Bone, RC; Clemmer, TP; Fisher, CJ; Metz, CA; Slotman, GJ, 1987) |
| "Sepsis is a syndrome of physiological, pathological, and biochemical disorders with several processes co-occurring; reactive oxygen species (ROS) production and apoptosis are 2 of them." | 1.72 | Parenteral succinate reduces levels of reactive oxygen species without changing serum caspase-3 levels in septic rats. ( Alberto Stella, C; Alonso, M; Barrea, L; Burgos, H; Chapela, S; Frias-Toral, E; Muryan, A; Muscogiuri, G; Ricart, M; Schiel, A, 2022) |
| " In heart fibers a dosage of 100 microg LPS." | 1.31 | Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function. ( Gellerich, FN; Neuhof, C; Opalka, JR; Trumbeckaite, S; Zierz, S, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Zhang, H | 1 |
| Zhang, X | 1 |
| Chen, Q | 1 |
| Xia, L | 1 |
| Feng, K | 1 |
| Dai, W | 1 |
| Liu, L | 1 |
| Li, S | 1 |
| Gou, Y | 1 |
| Chen, Z | 1 |
| Chen, G | 1 |
| Fu, X | 1 |
| Chapela, S | 1 |
| Muscogiuri, G | 1 |
| Barrea, L | 1 |
| Frias-Toral, E | 1 |
| Burgos, H | 1 |
| Ricart, M | 1 |
| Muryan, A | 2 |
| Schiel, A | 1 |
| Alonso, M | 2 |
| Alberto Stella, C | 1 |
| Chapela, SP | 1 |
| Burgos, I | 1 |
| Congost, C | 1 |
| Canzonieri, R | 1 |
| Stella, CA | 1 |
| Fry, DE | 1 |
| Kaelin, CR | 1 |
| Giammara, BL | 1 |
| Rink, RD | 1 |
| Taylor, DE | 1 |
| Ghio, AJ | 1 |
| Piantadosi, CA | 1 |
| Ferreira, FL | 1 |
| Ladrière, L | 1 |
| Vincent, JL | 1 |
| Malaisse, WJ | 1 |
| Trumbeckaite, S | 1 |
| Opalka, JR | 1 |
| Neuhof, C | 1 |
| Zierz, S | 1 |
| Gellerich, FN | 1 |
| Bone, RC | 1 |
| Fisher, CJ | 1 |
| Clemmer, TP | 1 |
| Slotman, GJ | 1 |
| Metz, CA | 1 |
1 review available for succinic acid and Blood Poisoning
| Article | Year |
|---|---|
Role of succinic acid in the regulation of sepsis.
Topics: Epigenesis, Genetic; Humans; Protein Processing, Post-Translational; Sepsis; Succinic Acid | 2022 |
1 trial available for succinic acid and Blood Poisoning
| Article | Year |
|---|---|
Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Methyl | 1987 |
7 other studies available for succinic acid and Blood Poisoning
| Article | Year |
|---|---|
Identification of biomarkers and the mechanisms of multiple trauma complicated with sepsis using metabolomics.
Topics: Biomarkers; Humans; Multiple Trauma; Sepsis; Succinic Acid; Uracil; Uridine | 2022 |
Parenteral succinate reduces levels of reactive oxygen species without changing serum caspase-3 levels in septic rats.
Topics: Animals; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sepsis; Succinates; Succinic Acid | 2022 |
Parenteral Succinate Reduces Systemic ROS Production in Septic Rats, but It Does Not Reduce Creatinine Levels.
Topics: Animals; Cecum; Creatinine; Ligation; Male; Oxidation-Reduction; Parenteral Nutrition; Rats; Rats, S | 2018 |
Alterations of oxygen metabolism in experimental bacteremia.
Topics: Animals; Blood Glucose; Carbon Dioxide; Escherichia coli Infections; Glutamates; Glutamic Acid; Hydr | 1981 |
Reactive oxygen species produced by liver mitochondria of rats in sepsis.
Topics: Animals; Cell-Free System; Cyanides; Electron Transport; Hydrogen Peroxide; Hydroxybenzoates; Hydrox | 1995 |
Prolongation of survival time by infusion of succinic acid dimethyl ester in a caecal ligation and perforation model of sepsis.
Topics: Animals; Cecum; Disease Models, Animal; Female; Ligation; Peritonitis; Punctures; Rats; Rats, Wistar | 2000 |
Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function.
Topics: Animals; Carnitine; Cell Respiration; Electron Transport; Female; Heart; In Vitro Techniques; Lipopo | 2001 |