succinic acid has been researched along with Arthritis, Rheumatoid in 7 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cinnamaldehyde (CA) is an essential component of cinnamon (Cinnamomum cassia Presland), which is often used as a flavoring condiment in beverages, pastries, perfumes, etc." | 5.56 | Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats. ( Chen, H; Fu, Y; Huang, JH; Liu, P; Pan, T; Wang, F; Wang, J; Wen, W; Xu, S, 2020) |
| "Cinnamaldehyde (CA) is an essential component of cinnamon (Cinnamomum cassia Presland), which is often used as a flavoring condiment in beverages, pastries, perfumes, etc." | 1.56 | Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats. ( Chen, H; Fu, Y; Huang, JH; Liu, P; Pan, T; Wang, F; Wang, J; Wen, W; Xu, S, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Souto-Carneiro, M | 1 |
| Tóth, L | 1 |
| Behnisch, R | 1 |
| Urbach, K | 1 |
| Klika, KD | 1 |
| Carvalho, RA | 1 |
| Lorenz, HM | 1 |
| Liu, P | 1 |
| Wang, J | 1 |
| Wen, W | 1 |
| Pan, T | 1 |
| Chen, H | 1 |
| Fu, Y | 1 |
| Wang, F | 1 |
| Huang, JH | 1 |
| Xu, S | 1 |
| Li, Y | 1 |
| Liu, Y | 1 |
| Wang, C | 1 |
| Xia, WR | 1 |
| Zheng, JY | 1 |
| Yang, J | 1 |
| Liu, B | 1 |
| Liu, JQ | 1 |
| Liu, LF | 1 |
| Littlewood-Evans, A | 1 |
| Sarret, S | 1 |
| Apfel, V | 1 |
| Loesle, P | 1 |
| Dawson, J | 1 |
| Zhang, J | 1 |
| Muller, A | 1 |
| Tigani, B | 1 |
| Kneuer, R | 1 |
| Patel, S | 1 |
| Valeaux, S | 1 |
| Gommermann, N | 1 |
| Rubic-Schneider, T | 1 |
| Junt, T | 1 |
| Carballido, JM | 1 |
| GILPIN, WA | 1 |
| CRAIN, DC | 1 |
| CANDELA, JL | 1 |
| GOMEZ ORBANEJA, J | 1 |
| LOPEZ de LETONA, A | 1 |
7 other studies available for succinic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Differences in the serum metabolome and lipidome identify potential biomarkers for seronegative rheumatoid arthritis versus psoriatic arthritis.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Arthritis, Psoriatic; Arthritis, Rhe | 2020 |
Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats.
Topics: Acrolein; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Hypoxia-Inducible Factor 1, alph | 2020 |
Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Humans; Hypoxia-Ind | 2018 |
GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Female; Humans; Interleukin-1beta; Lipopolysaccharides; Macrophages; | 2016 |
Treatment of rheumatoid arthritis and osteoarthritis with succinate-salicylate.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Humans; Osteoarthritis; Salicylates; Succinates; Succinic | 1955 |
Calcium succinate with aspirin as an anti-rheumatic agent.
Topics: Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Calcium; Humans; Osteoarthritis; Su | 1951 |
[Therapeutic effect of succinic acid in the treatment of rheumatoid arthritis and disseminated lupus erythematosus; preliminary note].
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Lupus Erythematosus, Systemic; Succinic Acid | 1951 |