succinic acid has been researched along with Anoxemia in 60 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study the authors examine the effects of acute hypoxia due to extracorporeal circulation (ECC) and the role played by L-carnitine treatment on some plasmatic metabolites linked to glycolytic cellular metabolism." | 9.07 | Metabolic aspects of acute tissue hypoxia during extracorporeal circulation and their modification induced by L-carnitine treatment. ( Cogliatti, A; Corbucci, GG; Menichetti, A; Nicoli, P; Ruvolo, C, 1992) |
| " It is well known that Puerarin and Tanshinone IIA (Pue-Tan) can significantly reduce interleukin-1β (IL-1β) levels and delay the atherosclerosis (AS) process clinically in China." | 8.31 | Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis. ( Cui, Y; Du, X; Gao, M; Hou, Y; Li, Z; Tian, Z; Wang, J; Xu, J, 2023) |
| "To establish cardiomyocyte hypoxia/reoxygenation injury model by culturing primary cardiomyocytes from suckling SD rats, in order to study the effect of succinic acid on LDH leakage rate cardiomyocyte ischemia/reperfusion injury." | 7.79 | [Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury]. ( Dong, W; Hou, JC; Li, L; Li, P; Liu, JX; Tang, XL; Zheng, YQ, 2013) |
| "Treatment of mice by a combination of succinic and glutamic acids prevented the metabolic disorders in the liver under conditions of normobaric hypoxia." | 7.75 | Effects of succinic and glutamic acid combination on energy metabolism in the liver of mice under conditions of hypoxia. ( Khazanov, VA; Kiselyova, AA; Vasilyev, KY, 2009) |
| "Prophylactic dietary intake of synthetic ubiquinone-10, succinic acid, or mixture of these substances prevented disturbances in aggregation and electrophoretic mobility of erythrocytes and inhibited lipid peroxidation in cells of rats with experimental epinephrine-induced toxemia." | 7.73 | Effect of ubiquinone-10 and succinic acid on functional characteristics of erythrocytes in rats with epinephrine toxemia. ( Deryugina, AV; Krylova, EV; Luk'yanova, LD, 2006) |
| "In experiments on rats with different resistance to hypoxia are investigated processes of mitochondrial respiration, oxidative phosphorylation and calcium capacity in liver under precursor nitric oxide L-arginine (600 mg/kg) and blockator nitric oxide synthase L-NNA (35 mg/kg) injections." | 7.71 | [State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine]. ( Kurhaliuk, NM, 2001) |
| "In this study the authors examine the effects of acute hypoxia due to extracorporeal circulation (ECC) and the role played by L-carnitine treatment on some plasmatic metabolites linked to glycolytic cellular metabolism." | 5.07 | Metabolic aspects of acute tissue hypoxia during extracorporeal circulation and their modification induced by L-carnitine treatment. ( Cogliatti, A; Corbucci, GG; Menichetti, A; Nicoli, P; Ruvolo, C, 1992) |
| " It is well known that Puerarin and Tanshinone IIA (Pue-Tan) can significantly reduce interleukin-1β (IL-1β) levels and delay the atherosclerosis (AS) process clinically in China." | 4.31 | Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis. ( Cui, Y; Du, X; Gao, M; Hou, Y; Li, Z; Tian, Z; Wang, J; Xu, J, 2023) |
| "To establish cardiomyocyte hypoxia/reoxygenation injury model by culturing primary cardiomyocytes from suckling SD rats, in order to study the effect of succinic acid on LDH leakage rate cardiomyocyte ischemia/reperfusion injury." | 3.79 | [Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury]. ( Dong, W; Hou, JC; Li, L; Li, P; Liu, JX; Tang, XL; Zheng, YQ, 2013) |
| "Pronounced antihypoxic and antioxidant effects of preventive injection of succinic acid, aminothiol antihypoxants gutimine and amtizol, and succinate-containing aminothiol antihypoxants gutimine succinate and amtizol succinate to Wistar rats with acute hypoxic hypoxia have been demonstrated." | 3.78 | Antihypoxic and antioxidant effects of exogenous succinic acid and aminothiol succinate-containing antihypoxants. ( Lukk, MV; Shabanov, PD; Zarubina, IV, 2012) |
| "Treatment of mice by a combination of succinic and glutamic acids prevented the metabolic disorders in the liver under conditions of normobaric hypoxia." | 3.75 | Effects of succinic and glutamic acid combination on energy metabolism in the liver of mice under conditions of hypoxia. ( Khazanov, VA; Kiselyova, AA; Vasilyev, KY, 2009) |
| "Prophylactic dietary intake of synthetic ubiquinone-10, succinic acid, or mixture of these substances prevented disturbances in aggregation and electrophoretic mobility of erythrocytes and inhibited lipid peroxidation in cells of rats with experimental epinephrine-induced toxemia." | 3.73 | Effect of ubiquinone-10 and succinic acid on functional characteristics of erythrocytes in rats with epinephrine toxemia. ( Deryugina, AV; Krylova, EV; Luk'yanova, LD, 2006) |
| "In experiments on rats with different resistance to hypoxia are investigated processes of mitochondrial respiration, oxidative phosphorylation and calcium capacity in liver under precursor nitric oxide L-arginine (600 mg/kg) and blockator nitric oxide synthase L-NNA (35 mg/kg) injections." | 3.71 | [State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine]. ( Kurhaliuk, NM, 2001) |
| "Evidence now suggests that, in anoxia-tolerant brains, mitochondria initiate responses aimed at suppressing electrical activity and energy use." | 1.91 | Two decades of research on anoxia tolerance - mitochondria, -omics and physiological diversity. ( Lefevre, S; Nilsson, GE, 2023) |
| "Extremely anoxia-tolerant animals, such as freshwater turtles, survive anoxia and reoxygenation without sustaining tissue damage to their hearts." | 1.91 | Low production of mitochondrial reactive oxygen species after anoxia and reoxygenation in turtle hearts. ( Bundgaard, A; Fago, A; Galli, GLJ; Gruszczyk, AV; James, AM; McIntyre, A; Murphy, MP; Prag, HA; Ruhr, IM; Williams, C, 2023) |
| "Hypoxia from lung injury is mainly regulated by hypoxia-inducible factor 1α (HIF-1α)." | 1.91 | Role of succinate in airway epithelial cell regulation following traumatic lung injury. ( Aktay, S; Arnipalli, MS; Pennathur, S; Raghavendran, K; Sathyarajan, DT; Solanki, S; Suresh, MV; Yalamanchili, G, 2023) |
| "Upon reoxygenation after anoxia the succinate that had accumulated during anoxia was rapidly oxidized in association with extensive mitochondrial superoxide/hydrogen peroxide production and cell injury, mimicking reperfusion injury." | 1.72 | Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury. ( Allen, FM; Bates, GR; Burger, N; Casey, AM; Gruszczyk, AV; Hall, AR; James, AM; Krieg, T; Murphy, MP; Prag, HA; Saeb-Parsy, K, 2022) |
| "We assessed the anoxia tolerance of A." | 1.34 | Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis. ( Fan, TW; Higashi, R; Lopez, JP; Podrabsky, JE; Somero, GN, 2007) |
| "Exposure to anoxia caused an increase in the levels of succinate (6 and 18 h) and acetate and propionate (18 h) with respect to control specimens." | 1.31 | Metabolic responses of the limpet Patella caerulea (L.) to anoxia and dehydration. ( Bruschini, C; Chelazzi, G; Moneti, G; Pazzagli, L; Pieraccini, G; Santini, G, 2001) |
| "Glycogen was sometimes only barely detectable due to the low natural abundance level of 13C." | 1.28 | In vivo 13C-NMR studies on the metabolism of the lugworm Arenicola marina. ( Juretschke, HP; Kamp, G, 1990) |
| "During anoxia, hyperglycemic cats showed higher brain lactate levels (26 versus 20 mumol/g), but similar ATP and phosphocreatine concentrations, compared with normoglycemic cats." | 1.28 | Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates. ( Kleinholz, M; Myers, RE; Wagner, KR, 1989) |
| "At the end of anoxia, hyperglycemic cats exhibited significantly higher cortical lactate and glucose levels but similarly reduced high-energy phosphate concentrations compared to normoglycemic cats." | 1.27 | Hyperglycemia preserves brain mitochondrial respiration during anoxia. ( Myers, RE; Wagner, KR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (10.00) | 18.7374 |
| 1990's | 4 (6.67) | 18.2507 |
| 2000's | 20 (33.33) | 29.6817 |
| 2010's | 15 (25.00) | 24.3611 |
| 2020's | 15 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, X | 1 |
| Liu, DH | 1 |
| Chen, T | 1 |
| Zhang, J | 2 |
| Wang, CL | 1 |
| Gruszczyk, AV | 3 |
| Casey, AM | 1 |
| James, AM | 4 |
| Prag, HA | 2 |
| Burger, N | 1 |
| Bates, GR | 1 |
| Hall, AR | 1 |
| Allen, FM | 1 |
| Krieg, T | 1 |
| Saeb-Parsy, K | 1 |
| Murphy, MP | 4 |
| Sanchez, M | 1 |
| Hamel, D | 2 |
| Bajon, E | 1 |
| Duhamel, F | 1 |
| Bhosle, VK | 1 |
| Zhu, T | 1 |
| Rivera, JC | 1 |
| Dabouz, R | 1 |
| Nadeau-Vallée, M | 1 |
| Sitaras, N | 1 |
| Tremblay, DÉ | 1 |
| Omri, S | 1 |
| Habelrih, T | 1 |
| Rouget, R | 1 |
| Hou, X | 1 |
| Gobeil, F | 1 |
| Joyal, JS | 2 |
| Sapieha, P | 2 |
| Mitchell, G | 1 |
| Ribeiro-Da-Silva, A | 1 |
| Mohammad Nezhady, MA | 1 |
| Chemtob, S | 2 |
| Orlov, YP | 1 |
| Butrov, AV | 1 |
| Sviridov, SV | 1 |
| Afanasyev, VV | 1 |
| Germanova, E | 3 |
| Khmil, N | 3 |
| Pavlik, L | 3 |
| Mikheeva, I | 3 |
| Mironova, G | 3 |
| Lukyanova, L | 3 |
| Lefevre, S | 1 |
| Nilsson, GE | 1 |
| Bundgaard, A | 3 |
| Williams, C | 1 |
| McIntyre, A | 1 |
| Ruhr, IM | 1 |
| Galli, GLJ | 1 |
| Fago, A | 3 |
| Xu, J | 1 |
| Tian, Z | 1 |
| Li, Z | 1 |
| Du, X | 1 |
| Cui, Y | 1 |
| Wang, J | 1 |
| Gao, M | 1 |
| Hou, Y | 1 |
| Abdullah, S | 1 |
| Ghio, M | 1 |
| Cotton-Betteridge, A | 1 |
| Vinjamuri, A | 1 |
| Drury, R | 1 |
| Packer, J | 1 |
| Aras, O | 1 |
| Friedman, J | 1 |
| Karim, M | 1 |
| Engelhardt, D | 1 |
| Kosowski, E | 1 |
| Duong, K | 1 |
| Shaheen, F | 1 |
| McGrew, PR | 1 |
| Harris, CT | 1 |
| Reily, R | 1 |
| Sammarco, M | 1 |
| Chandra, PK | 1 |
| Pociask, D | 1 |
| Kolls, J | 1 |
| Katakam, PV | 1 |
| Smith, A | 1 |
| Taghavi, S | 1 |
| Duchesne, J | 1 |
| Jackson-Weaver, O | 1 |
| Suresh, MV | 1 |
| Aktay, S | 1 |
| Yalamanchili, G | 1 |
| Solanki, S | 1 |
| Sathyarajan, DT | 1 |
| Arnipalli, MS | 1 |
| Pennathur, S | 1 |
| Raghavendran, K | 1 |
| Devaux, JBL | 1 |
| Hickey, AJR | 1 |
| Renshaw, GMC | 1 |
| Vorobieva, VV | 1 |
| Shabanov, PD | 2 |
| Haider, F | 1 |
| Falfushynska, HI | 1 |
| Timm, S | 1 |
| Sokolova, IM | 1 |
| Jin, Z | 1 |
| Zhang, Q | 1 |
| Wondimu, E | 1 |
| Verma, R | 1 |
| Fu, M | 1 |
| Shuang, T | 1 |
| Arif, HM | 1 |
| Wu, L | 1 |
| Wang, R | 1 |
| Prikhodko, VA | 2 |
| Selizarova, NO | 2 |
| Okovityi, SV | 2 |
| Sahni, PV | 1 |
| Sosunov, S | 1 |
| Galkin, A | 1 |
| Niatsetskaya, Z | 1 |
| Starkov, A | 1 |
| Brookes, PS | 1 |
| Ten, VS | 1 |
| Joyce, W | 1 |
| Martin, J | 1 |
| Boruczkowski, D | 1 |
| Pujal, JM | 1 |
| Zdolińska-Malinowska, I | 1 |
| Tang, XL | 1 |
| Liu, JX | 1 |
| Li, P | 1 |
| Dong, W | 1 |
| Li, L | 1 |
| Zheng, YQ | 1 |
| Hou, JC | 1 |
| Melnytchuk, SD | 1 |
| Khyzhnyak, SV | 1 |
| Morozova, VS | 1 |
| Stepanova, LI | 1 |
| Umanskaya, AA | 1 |
| Voitsitsky, VM | 1 |
| Tretter, L | 1 |
| Patocs, A | 1 |
| Chinopoulos, C | 1 |
| Jones, R | 1 |
| McDonald, KE | 1 |
| Willson, JA | 1 |
| Ghesquière, B | 1 |
| Sammut, D | 1 |
| Daniel, E | 1 |
| Harris, AJ | 1 |
| Lewis, A | 1 |
| Thompson, AA | 1 |
| Dickinson, RS | 1 |
| Plant, T | 1 |
| Murphy, F | 1 |
| Sadiku, P | 1 |
| Keevil, BG | 1 |
| Carmeliet, P | 1 |
| Whyte, MK | 1 |
| Newell-Price, J | 1 |
| Walmsley, SR | 1 |
| Vasilyev, KY | 2 |
| Khazanov, VA | 2 |
| Tissot van Patot, MC | 1 |
| Serkova, NJ | 1 |
| Haschke, M | 1 |
| Kominsky, DJ | 1 |
| Roach, RC | 1 |
| Christians, U | 1 |
| Henthorn, TK | 1 |
| Honigman, B | 1 |
| Zaniolo, K | 1 |
| Kiselyova, AA | 1 |
| Rocha, M | 1 |
| Licausi, F | 1 |
| Araújo, WL | 1 |
| Nunes-Nesi, A | 1 |
| Sodek, L | 1 |
| Fernie, AR | 1 |
| van Dongen, JT | 1 |
| Hawkins, BJ | 1 |
| Levin, MD | 1 |
| Doonan, PJ | 1 |
| Petrenko, NB | 1 |
| Davis, CW | 1 |
| Patel, VV | 1 |
| Madesh, M | 1 |
| Kawamura, A | 1 |
| Loenarz, C | 1 |
| Schofield, CJ | 1 |
| Strahl, J | 1 |
| Brey, T | 1 |
| Philipp, EE | 1 |
| Thorarinsdóttir, G | 1 |
| Fischer, N | 1 |
| Wessels, W | 1 |
| Abele, D | 1 |
| Frizzell, N | 1 |
| Thomas, SA | 1 |
| Carson, JA | 1 |
| Baynes, JW | 1 |
| Zarubina, IV | 1 |
| Lukk, MV | 1 |
| Holt, SJ | 1 |
| Riddle, DL | 1 |
| D'Angelo, G | 1 |
| Duplan, E | 1 |
| Boyer, N | 1 |
| Vigne, P | 1 |
| Frelin, C | 1 |
| Kurhaliuk, NM | 3 |
| Serebrovs'ka, TV | 1 |
| DIAMANT, B | 1 |
| CASTEX, MR | 1 |
| CAMPONOVO, LE | 1 |
| LABOURT, FE | 1 |
| FIRMAT, J | 1 |
| Okino, S | 1 |
| Inui, M | 1 |
| Yukawa, H | 1 |
| Yen, DH | 1 |
| Chan, JY | 1 |
| Huang, CI | 1 |
| Lee, CH | 1 |
| Chan, SH | 1 |
| Chang, AY | 1 |
| Kotsiuruba, AV | 1 |
| Sahach, VF | 1 |
| Deryugina, AV | 1 |
| Krylova, EV | 1 |
| Luk'yanova, LD | 1 |
| Le Moullac, G | 1 |
| Bacca, H | 1 |
| Huvet, A | 1 |
| Moal, J | 1 |
| Pouvreau, S | 1 |
| Van Wormhoudt, A | 1 |
| Hines, A | 1 |
| Oladiran, GS | 1 |
| Bignell, JP | 1 |
| Stentiford, GD | 1 |
| Viant, MR | 1 |
| Podrabsky, JE | 1 |
| Lopez, JP | 1 |
| Fan, TW | 1 |
| Higashi, R | 1 |
| Somero, GN | 1 |
| Nickols, NG | 1 |
| Jacobs, CS | 1 |
| Farkas, ME | 1 |
| Dervan, PB | 1 |
| Kostenko, VO | 1 |
| Du, G | 1 |
| Mouithys-Mickalad, A | 1 |
| Sluse, FE | 1 |
| Boutilier, RG | 1 |
| West, TG | 1 |
| Webber, DM | 1 |
| Pogson, GH | 1 |
| Mesa, KA | 1 |
| Wells, J | 1 |
| Wells, MJ | 1 |
| Leach, RM | 1 |
| Hill, HM | 1 |
| Snetkov, VA | 1 |
| Robertson, TP | 1 |
| Ward, JP | 1 |
| Santini, G | 1 |
| Bruschini, C | 1 |
| Pazzagli, L | 1 |
| Pieraccini, G | 1 |
| Moneti, G | 1 |
| Chelazzi, G | 1 |
| Van Cappellen Van Walsum, AM | 1 |
| Jongsma, HW | 1 |
| Wevers, RA | 1 |
| Nijhuis, JG | 1 |
| Crevels, J | 1 |
| Engelke, UF | 1 |
| De Abreu, RA | 1 |
| Moolenaar, SH | 1 |
| Oeseburg, B | 1 |
| Nijland, R | 1 |
| Corbucci, GG | 1 |
| Menichetti, A | 1 |
| Cogliatti, A | 1 |
| Nicoli, P | 1 |
| Ruvolo, C | 1 |
| Juretschke, HP | 1 |
| Kamp, G | 1 |
| Wagner, KR | 2 |
| Kleinholz, M | 1 |
| Myers, RE | 2 |
| Hohl, C | 1 |
| Oestreich, R | 1 |
| Rösen, P | 1 |
| Wiesner, R | 1 |
| Grieshaber, M | 1 |
| Bonventre, JV | 1 |
| Cheung, JY | 1 |
4 reviews available for succinic acid and Anoxemia
| Article | Year |
|---|---|
[Molecular mechanisms for hypoxia development and adaptation to it. Part I].
Topics: Humans; Hypoxia; Signal Transduction; Succinic Acid | 2021 |
[Molecular mechanisms of hypoxia and adaptation to it. Part II].
Topics: Humans; Hypoxia; Succinates; Succinic Acid | 2021 |
Autologous cord blood in children with cerebral palsy: a review.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Brain Diseases; Brain Injuries; Carnitine; Cerebral Pal | 2019 |
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
Topics: Carcinogenesis; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, | 2016 |
1 trial available for succinic acid and Anoxemia
| Article | Year |
|---|---|
Metabolic aspects of acute tissue hypoxia during extracorporeal circulation and their modification induced by L-carnitine treatment.
Topics: Bicarbonates; Carnitine; Double-Blind Method; Extracorporeal Circulation; Female; Fumarates; Humans; | 1992 |
55 other studies available for succinic acid and Anoxemia
| Article | Year |
|---|---|
Watercore Pear Fruit Respiration Changed and Accumulated γ-Aminobutyric Acid (GABA) in Response to Inner Hypoxia Stress.
Topics: Fruit; gamma-Aminobutyric Acid; Hypoxia; Pyrus; Respiration; Succinic Acid | 2022 |
Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; Energy Metabolism; Hypoxia; Ischemia; Lactates; Mice; Myocytes, Car | 2022 |
The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions.
Topics: Animals; Cell Membrane; Endoplasmic Reticulum; Hypoxia; Mice; Receptors, G-Protein-Coupled; Succinat | 2022 |
[Succinate salts in solving the «oxygen paradox» of reperfusion].
Topics: Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Oxygen; Reactive Oxygen Species; Reperfu | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula | 2022 |
Two decades of research on anoxia tolerance - mitochondria, -omics and physiological diversity.
Topics: Animals; Brain; Hypoxia; Mitochondria; Reactive Oxygen Species; Succinates; Succinic Acid; Vertebrat | 2023 |
Low production of mitochondrial reactive oxygen species after anoxia and reoxygenation in turtle hearts.
Topics: Animals; Hydrogen Peroxide; Hypoxia; Mammals; Mitochondria, Heart; Reactive Oxygen Species; Succinat | 2023 |
Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis.
Topics: Animals; Atherosclerosis; Hypoxia; Interleukin-1beta; Mice; Molecular Docking Simulation; Plaque, At | 2023 |
Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage.
Topics: Animals; Endothelial Cells; Hemorrhage; Hypoxia; Lipid Metabolism; Rats; Succinates; Succinic Acid | 2023 |
Role of succinate in airway epithelial cell regulation following traumatic lung injury.
Topics: Animals; Epithelial Cells; Humans; Hypoxia; Inflammation; Lung; Lung Injury; Mice; Respiratory Distr | 2023 |
Succinate-mediated reactive oxygen species production in the anoxia-tolerant epaulette (
Topics: Animals; Floors and Floorcoverings; Hypoxia; Oxygen; Reactive Oxygen Species; Sharks; Succinic Acid | 2023 |
Tissue-Specific Peculiarities of Vibration-Induced Hypoxia in Rabbit Liver and Kidney.
Topics: 2,4-Dinitrophenol; Animals; Electron Transport; Flavin-Adenine Dinucleotide; Hypoxia; Kidney; Liver; | 2019 |
Effects of hypoxia and reoxygenation on intermediary metabolite homeostasis of marine bivalves Mytilus edulis and Crassostrea gigas.
Topics: Aerobiosis; Amino Acids; Animals; Crassostrea; Energy Metabolism; gamma-Aminobutyric Acid; Homeostas | 2020 |
H
Topics: Adenosine Triphosphate; Animals; Chickens; Electron Transport; Energy Metabolism; Erythrocytes; Fema | 2020 |
Krebs cycle metabolites and preferential succinate oxidation following neonatal hypoxic-ischemic brain injury in mice.
Topics: Animals; Animals, Newborn; Chromatography, High Pressure Liquid; Citric Acid Cycle; Electrons; Hydro | 2018 |
Suppression of reactive oxygen species generation in heart mitochondria from anoxic turtles: the role of complex I
Topics: Adaptation, Physiological; Animals; Electron Transport Complex I; Glucosides; Hypoxia; Mitochondria, | 2018 |
Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury.
Topics: Animals; Heart; Hypoxia; Myocardium; Reactive Oxygen Species; Reperfusion Injury; Succinic Acid; Tur | 2019 |
[Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury].
Topics: Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cell Survival; Cells, Cultured; Female; Humans; Hypoxia | 2013 |
[THE ENERGY FUNCTION OF RAT CARDIAC MITOCHONDRIA UNDER ARTIFICIAL HYPOBIOSIS].
Topics: Animals; Animals, Outbred Strains; Body Temperature; Carbon Dioxide; Cell Fractionation; Electron Tr | 2015 |
Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression.
Topics: Cell Survival; Gene Expression Regulation; Germ-Line Mutation; Humans; Hypoxia; Hypoxia-Inducible Fa | 2016 |
Effect of cerebronorm on energy metabolism and lipid peroxidation in rat brain during hypoxia.
Topics: Animals; Brain; Energy Metabolism; Hypoxia; Inosine Diphosphate; Lipid Peroxidation; Male; Mitochond | 2007 |
Enhanced leukocyte HIF-1alpha and HIF-1 DNA binding in humans after rapid ascent to 4300 m.
Topics: Adult; Altitude; Biomarkers; Dinoprost; DNA; Female; Free Radicals; Glutathione; Heart Rate; Humans; | 2009 |
[Supply and demand: the influence of energy metabolism on angiogenesis].
Topics: Animals; Diabetic Retinopathy; Energy Metabolism; Humans; Hypoxia; Infant, Newborn; Injections; Isch | 2009 |
Effects of succinic and glutamic acid combination on energy metabolism in the liver of mice under conditions of hypoxia.
Topics: Animals; Drug Combinations; Energy Metabolism; Glutamic Acid; Hypoxia; Lipid Peroxidation; Liver; Ma | 2009 |
Glycolysis and the tricarboxylic acid cycle are linked by alanine aminotransferase during hypoxia induced by waterlogging of Lotus japonicus.
Topics: Adenosine Triphosphate; Alanine; Alanine Transaminase; Citric Acid Cycle; Fermentation; Gene Express | 2010 |
Mitochondrial complex II prevents hypoxic but not calcium- and proapoptotic Bcl-2 protein-induced mitochondrial membrane potential loss.
Topics: Adenosine Triphosphate; Animals; Calcium; Electron Transport Complex II; Humans; Hypoxia; Membrane P | 2010 |
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry.
Topics: Citric Acid Cycle; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regul | 2011 |
Physiological responses to self-induced burrowing and metabolic rate depression in the ocean quahog Arctica islandica.
Topics: Animals; Antioxidants; Basal Metabolism; Bivalvia; Catalase; Gills; Hypoxia; Oxidative Stress; Oxyge | 2011 |
Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity.
Topics: 3T3 Cells; Adipocytes; Animals; Blotting, Western; Cell Survival; Citric Acid Cycle; Electrophoresis | 2012 |
Antihypoxic and antioxidant effects of exogenous succinic acid and aminothiol succinate-containing antihypoxants.
Topics: Animals; Antioxidants; Guanylthiourea; Hypoxia; Lipid Peroxidation; Male; Rats; Rats, Wistar; Succin | 2012 |
SAGE surveys C. elegans carbohydrate metabolism: evidence for an anaerobic shift in the long-lived dauer larva.
Topics: Alcohols; Anaerobiosis; Animals; Base Sequence; Caenorhabditis elegans; Carbohydrate Metabolism; Cit | 2003 |
Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
Topics: Animals; Blotting, Northern; Blotting, Western; DNA-Binding Proteins; Down-Regulation; Feedback, Phy | 2003 |
[Tricarboxylic acid cycle in energy metabolism and antioxidant cell defense in acute hypoxia].
Topics: Acute Disease; Animals; Antioxidants; Catalase; Cholinergic Antagonists; Citric Acid Cycle; Disease | 2003 |
Comparison between the effects of glucose and sodium succinate on the in vitro release of histamine from guinea-pig and rat lung tissue.
Topics: Anaphylaxis; Animals; Glucose; Guinea Pigs; Histamine; Histamine Release; Hypoxia; In Vitro Techniqu | 1962 |
[Succinic acid and anoxia].
Topics: Hypoxia; Succinates; Succinic Acid | 1952 |
Production of organic acids by Corynebacterium glutamicum under oxygen deprivation.
Topics: Corynebacterium glutamicum; Hypoxia; Lactic Acid; Succinic Acid | 2005 |
Coenzyme q10 confers cardiovascular protection against acute mevinphos intoxication by ameliorating bioenergetic failure and hypoxia in the rostral ventrolateral medulla of the rat.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Cardiovascular System; Coenzymes; Electron Transport | 2005 |
[The modification of nitric oxide production by exogenous substrates of Krebs cycle during acute hypoxia].
Topics: Acute Disease; Animals; Biogenic Polyamines; Citric Acid Cycle; Erythrocytes; Hypoxia; Ketoglutaric | 2005 |
Effect of ubiquinone-10 and succinic acid on functional characteristics of erythrocytes in rats with epinephrine toxemia.
Topics: Animals; Epinephrine; Erythrocyte Aggregation; Erythrocytes; Female; Hypoxia; Lipid Peroxidation; Mo | 2006 |
Transcriptional regulation of pyruvate kinase and phosphoenolpyruvate carboxykinase in the adductor muscle of the oyster Crassostrea gigas during prolonged hypoxia.
Topics: Amino Acid Sequence; Animals; Base Sequence; Crassostrea; Digestive System; DNA Primers; Gene Expres | 2007 |
Direct sampling of organisms from the field and knowledge of their phenotype: key recommendations for environmental metabolomics.
Topics: Acetoacetates; Amino Acids; Animals; Betaine; Female; Hypoxia; Male; Muscles; Mytilus; Phenotype; Pi | 2007 |
Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis.
Topics: Amino Acids; Animals; Embryo, Nonmammalian; gamma-Aminobutyric Acid; Hypoxia; Killifishes; Lactic Ac | 2007 |
Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface.
Topics: Base Sequence; Cell Death; DNA; Hypoxia; Hypoxia-Inducible Factor 1; Models, Molecular; Nucleic Acid | 2007 |
[Mitochondrial respiration and oxidative phosphorylation in the kidneys of white rats under conditions of hemic hypoxia and the use of different suture materials].
Topics: Animals; Female; Hypoxia; Kidney; Male; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation | 1998 |
Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation in vitro.
Topics: Adenosine Diphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Respiration | 1998 |
The protective effects of hypoxia-induced hypometabolism in the Nautilus.
Topics: Acid-Base Equilibrium; Adaptation, Physiological; Animals; Arginine; Basal Metabolism; Carbon Dioxid | 2000 |
[State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine].
Topics: Adenosine Diphosphate; Animals; Arginine; Calcium; Enzyme Inhibitors; Hypoxia; Ketoglutaric Acids; M | 2001 |
Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor.
Topics: Animals; Antimetabolites; Cyanides; Deoxyglucose; Electron Transport; Electron Transport Complex III | 2001 |
Metabolic responses of the limpet Patella caerulea (L.) to anoxia and dehydration.
Topics: Acetates; Adaptation, Physiological; Alanine; Animals; Aspartic Acid; Dehydration; Hypoxia; Mollusca | 2001 |
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Femal | 2002 |
In vivo 13C-NMR studies on the metabolism of the lugworm Arenicola marina.
Topics: Alanine; Animals; Carbon; Glucose; Glycogen; Hydrogen-Ion Concentration; Hypoxia; Magnetic Resonance | 1990 |
Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Brain; Carbon Dioxide; Cats; | 1989 |
Hyperglycemia preserves brain mitochondrial respiration during anoxia.
Topics: Animals; Brain; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cats; Glutamates; Glutamic Acid; | 1986 |
Evidence for succinate production by reduction of fumarate during hypoxia in isolated adult rat heart cells.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Chromatography, High Pressure Liquid; Deoxyglucose; | 1987 |
Effects of metabolic acidosis on viability of cells exposed to anoxia.
Topics: Acidosis; Adenine Nucleotides; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Cytosol; Fem | 1985 |