Page last updated: 2024-10-20

succinic acid and Anoxemia

succinic acid has been researched along with Anoxemia in 60 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

Research Excerpts

ExcerptRelevanceReference
"In this study the authors examine the effects of acute hypoxia due to extracorporeal circulation (ECC) and the role played by L-carnitine treatment on some plasmatic metabolites linked to glycolytic cellular metabolism."9.07Metabolic aspects of acute tissue hypoxia during extracorporeal circulation and their modification induced by L-carnitine treatment. ( Cogliatti, A; Corbucci, GG; Menichetti, A; Nicoli, P; Ruvolo, C, 1992)
" It is well known that Puerarin and Tanshinone IIA (Pue-Tan) can significantly reduce interleukin-1β (IL-1β) levels and delay the atherosclerosis (AS) process clinically in China."8.31Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis. ( Cui, Y; Du, X; Gao, M; Hou, Y; Li, Z; Tian, Z; Wang, J; Xu, J, 2023)
"To establish cardiomyocyte hypoxia/reoxygenation injury model by culturing primary cardiomyocytes from suckling SD rats, in order to study the effect of succinic acid on LDH leakage rate cardiomyocyte ischemia/reperfusion injury."7.79[Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury]. ( Dong, W; Hou, JC; Li, L; Li, P; Liu, JX; Tang, XL; Zheng, YQ, 2013)
"Treatment of mice by a combination of succinic and glutamic acids prevented the metabolic disorders in the liver under conditions of normobaric hypoxia."7.75Effects of succinic and glutamic acid combination on energy metabolism in the liver of mice under conditions of hypoxia. ( Khazanov, VA; Kiselyova, AA; Vasilyev, KY, 2009)
"Prophylactic dietary intake of synthetic ubiquinone-10, succinic acid, or mixture of these substances prevented disturbances in aggregation and electrophoretic mobility of erythrocytes and inhibited lipid peroxidation in cells of rats with experimental epinephrine-induced toxemia."7.73Effect of ubiquinone-10 and succinic acid on functional characteristics of erythrocytes in rats with epinephrine toxemia. ( Deryugina, AV; Krylova, EV; Luk'yanova, LD, 2006)
"In experiments on rats with different resistance to hypoxia are investigated processes of mitochondrial respiration, oxidative phosphorylation and calcium capacity in liver under precursor nitric oxide L-arginine (600 mg/kg) and blockator nitric oxide synthase L-NNA (35 mg/kg) injections."7.71[State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine]. ( Kurhaliuk, NM, 2001)
"In this study the authors examine the effects of acute hypoxia due to extracorporeal circulation (ECC) and the role played by L-carnitine treatment on some plasmatic metabolites linked to glycolytic cellular metabolism."5.07Metabolic aspects of acute tissue hypoxia during extracorporeal circulation and their modification induced by L-carnitine treatment. ( Cogliatti, A; Corbucci, GG; Menichetti, A; Nicoli, P; Ruvolo, C, 1992)
" It is well known that Puerarin and Tanshinone IIA (Pue-Tan) can significantly reduce interleukin-1β (IL-1β) levels and delay the atherosclerosis (AS) process clinically in China."4.31Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis. ( Cui, Y; Du, X; Gao, M; Hou, Y; Li, Z; Tian, Z; Wang, J; Xu, J, 2023)
"To establish cardiomyocyte hypoxia/reoxygenation injury model by culturing primary cardiomyocytes from suckling SD rats, in order to study the effect of succinic acid on LDH leakage rate cardiomyocyte ischemia/reperfusion injury."3.79[Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury]. ( Dong, W; Hou, JC; Li, L; Li, P; Liu, JX; Tang, XL; Zheng, YQ, 2013)
"Pronounced antihypoxic and antioxidant effects of preventive injection of succinic acid, aminothiol antihypoxants gutimine and amtizol, and succinate-containing aminothiol antihypoxants gutimine succinate and amtizol succinate to Wistar rats with acute hypoxic hypoxia have been demonstrated."3.78Antihypoxic and antioxidant effects of exogenous succinic acid and aminothiol succinate-containing antihypoxants. ( Lukk, MV; Shabanov, PD; Zarubina, IV, 2012)
"Treatment of mice by a combination of succinic and glutamic acids prevented the metabolic disorders in the liver under conditions of normobaric hypoxia."3.75Effects of succinic and glutamic acid combination on energy metabolism in the liver of mice under conditions of hypoxia. ( Khazanov, VA; Kiselyova, AA; Vasilyev, KY, 2009)
"Prophylactic dietary intake of synthetic ubiquinone-10, succinic acid, or mixture of these substances prevented disturbances in aggregation and electrophoretic mobility of erythrocytes and inhibited lipid peroxidation in cells of rats with experimental epinephrine-induced toxemia."3.73Effect of ubiquinone-10 and succinic acid on functional characteristics of erythrocytes in rats with epinephrine toxemia. ( Deryugina, AV; Krylova, EV; Luk'yanova, LD, 2006)
"In experiments on rats with different resistance to hypoxia are investigated processes of mitochondrial respiration, oxidative phosphorylation and calcium capacity in liver under precursor nitric oxide L-arginine (600 mg/kg) and blockator nitric oxide synthase L-NNA (35 mg/kg) injections."3.71[State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine]. ( Kurhaliuk, NM, 2001)
"Evidence now suggests that, in anoxia-tolerant brains, mitochondria initiate responses aimed at suppressing electrical activity and energy use."1.91Two decades of research on anoxia tolerance - mitochondria, -omics and physiological diversity. ( Lefevre, S; Nilsson, GE, 2023)
"Extremely anoxia-tolerant animals, such as freshwater turtles, survive anoxia and reoxygenation without sustaining tissue damage to their hearts."1.91Low production of mitochondrial reactive oxygen species after anoxia and reoxygenation in turtle hearts. ( Bundgaard, A; Fago, A; Galli, GLJ; Gruszczyk, AV; James, AM; McIntyre, A; Murphy, MP; Prag, HA; Ruhr, IM; Williams, C, 2023)
"Hypoxia from lung injury is mainly regulated by hypoxia-inducible factor 1α (HIF-1α)."1.91Role of succinate in airway epithelial cell regulation following traumatic lung injury. ( Aktay, S; Arnipalli, MS; Pennathur, S; Raghavendran, K; Sathyarajan, DT; Solanki, S; Suresh, MV; Yalamanchili, G, 2023)
"Upon reoxygenation after anoxia the succinate that had accumulated during anoxia was rapidly oxidized in association with extensive mitochondrial superoxide/hydrogen peroxide production and cell injury, mimicking reperfusion injury."1.72Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury. ( Allen, FM; Bates, GR; Burger, N; Casey, AM; Gruszczyk, AV; Hall, AR; James, AM; Krieg, T; Murphy, MP; Prag, HA; Saeb-Parsy, K, 2022)
"We assessed the anoxia tolerance of A."1.34Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis. ( Fan, TW; Higashi, R; Lopez, JP; Podrabsky, JE; Somero, GN, 2007)
"Exposure to anoxia caused an increase in the levels of succinate (6 and 18 h) and acetate and propionate (18 h) with respect to control specimens."1.31Metabolic responses of the limpet Patella caerulea (L.) to anoxia and dehydration. ( Bruschini, C; Chelazzi, G; Moneti, G; Pazzagli, L; Pieraccini, G; Santini, G, 2001)
"Glycogen was sometimes only barely detectable due to the low natural abundance level of 13C."1.28In vivo 13C-NMR studies on the metabolism of the lugworm Arenicola marina. ( Juretschke, HP; Kamp, G, 1990)
"During anoxia, hyperglycemic cats showed higher brain lactate levels (26 versus 20 mumol/g), but similar ATP and phosphocreatine concentrations, compared with normoglycemic cats."1.28Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates. ( Kleinholz, M; Myers, RE; Wagner, KR, 1989)
"At the end of anoxia, hyperglycemic cats exhibited significantly higher cortical lactate and glucose levels but similarly reduced high-energy phosphate concentrations compared to normoglycemic cats."1.27Hyperglycemia preserves brain mitochondrial respiration during anoxia. ( Myers, RE; Wagner, KR, 1986)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19906 (10.00)18.7374
1990's4 (6.67)18.2507
2000's20 (33.33)29.6817
2010's15 (25.00)24.3611
2020's15 (25.00)2.80

Authors

AuthorsStudies
Liu, X1
Liu, DH1
Chen, T1
Zhang, J2
Wang, CL1
Gruszczyk, AV3
Casey, AM1
James, AM4
Prag, HA2
Burger, N1
Bates, GR1
Hall, AR1
Allen, FM1
Krieg, T1
Saeb-Parsy, K1
Murphy, MP4
Sanchez, M1
Hamel, D2
Bajon, E1
Duhamel, F1
Bhosle, VK1
Zhu, T1
Rivera, JC1
Dabouz, R1
Nadeau-Vallée, M1
Sitaras, N1
Tremblay, DÉ1
Omri, S1
Habelrih, T1
Rouget, R1
Hou, X1
Gobeil, F1
Joyal, JS2
Sapieha, P2
Mitchell, G1
Ribeiro-Da-Silva, A1
Mohammad Nezhady, MA1
Chemtob, S2
Orlov, YP1
Butrov, AV1
Sviridov, SV1
Afanasyev, VV1
Germanova, E3
Khmil, N3
Pavlik, L3
Mikheeva, I3
Mironova, G3
Lukyanova, L3
Lefevre, S1
Nilsson, GE1
Bundgaard, A3
Williams, C1
McIntyre, A1
Ruhr, IM1
Galli, GLJ1
Fago, A3
Xu, J1
Tian, Z1
Li, Z1
Du, X1
Cui, Y1
Wang, J1
Gao, M1
Hou, Y1
Abdullah, S1
Ghio, M1
Cotton-Betteridge, A1
Vinjamuri, A1
Drury, R1
Packer, J1
Aras, O1
Friedman, J1
Karim, M1
Engelhardt, D1
Kosowski, E1
Duong, K1
Shaheen, F1
McGrew, PR1
Harris, CT1
Reily, R1
Sammarco, M1
Chandra, PK1
Pociask, D1
Kolls, J1
Katakam, PV1
Smith, A1
Taghavi, S1
Duchesne, J1
Jackson-Weaver, O1
Suresh, MV1
Aktay, S1
Yalamanchili, G1
Solanki, S1
Sathyarajan, DT1
Arnipalli, MS1
Pennathur, S1
Raghavendran, K1
Devaux, JBL1
Hickey, AJR1
Renshaw, GMC1
Vorobieva, VV1
Shabanov, PD2
Haider, F1
Falfushynska, HI1
Timm, S1
Sokolova, IM1
Jin, Z1
Zhang, Q1
Wondimu, E1
Verma, R1
Fu, M1
Shuang, T1
Arif, HM1
Wu, L1
Wang, R1
Prikhodko, VA2
Selizarova, NO2
Okovityi, SV2
Sahni, PV1
Sosunov, S1
Galkin, A1
Niatsetskaya, Z1
Starkov, A1
Brookes, PS1
Ten, VS1
Joyce, W1
Martin, J1
Boruczkowski, D1
Pujal, JM1
Zdolińska-Malinowska, I1
Tang, XL1
Liu, JX1
Li, P1
Dong, W1
Li, L1
Zheng, YQ1
Hou, JC1
Melnytchuk, SD1
Khyzhnyak, SV1
Morozova, VS1
Stepanova, LI1
Umanskaya, AA1
Voitsitsky, VM1
Tretter, L1
Patocs, A1
Chinopoulos, C1
Jones, R1
McDonald, KE1
Willson, JA1
Ghesquière, B1
Sammut, D1
Daniel, E1
Harris, AJ1
Lewis, A1
Thompson, AA1
Dickinson, RS1
Plant, T1
Murphy, F1
Sadiku, P1
Keevil, BG1
Carmeliet, P1
Whyte, MK1
Newell-Price, J1
Walmsley, SR1
Vasilyev, KY2
Khazanov, VA2
Tissot van Patot, MC1
Serkova, NJ1
Haschke, M1
Kominsky, DJ1
Roach, RC1
Christians, U1
Henthorn, TK1
Honigman, B1
Zaniolo, K1
Kiselyova, AA1
Rocha, M1
Licausi, F1
Araújo, WL1
Nunes-Nesi, A1
Sodek, L1
Fernie, AR1
van Dongen, JT1
Hawkins, BJ1
Levin, MD1
Doonan, PJ1
Petrenko, NB1
Davis, CW1
Patel, VV1
Madesh, M1
Kawamura, A1
Loenarz, C1
Schofield, CJ1
Strahl, J1
Brey, T1
Philipp, EE1
Thorarinsdóttir, G1
Fischer, N1
Wessels, W1
Abele, D1
Frizzell, N1
Thomas, SA1
Carson, JA1
Baynes, JW1
Zarubina, IV1
Lukk, MV1
Holt, SJ1
Riddle, DL1
D'Angelo, G1
Duplan, E1
Boyer, N1
Vigne, P1
Frelin, C1
Kurhaliuk, NM3
Serebrovs'ka, TV1
DIAMANT, B1
CASTEX, MR1
CAMPONOVO, LE1
LABOURT, FE1
FIRMAT, J1
Okino, S1
Inui, M1
Yukawa, H1
Yen, DH1
Chan, JY1
Huang, CI1
Lee, CH1
Chan, SH1
Chang, AY1
Kotsiuruba, AV1
Sahach, VF1
Deryugina, AV1
Krylova, EV1
Luk'yanova, LD1
Le Moullac, G1
Bacca, H1
Huvet, A1
Moal, J1
Pouvreau, S1
Van Wormhoudt, A1
Hines, A1
Oladiran, GS1
Bignell, JP1
Stentiford, GD1
Viant, MR1
Podrabsky, JE1
Lopez, JP1
Fan, TW1
Higashi, R1
Somero, GN1
Nickols, NG1
Jacobs, CS1
Farkas, ME1
Dervan, PB1
Kostenko, VO1
Du, G1
Mouithys-Mickalad, A1
Sluse, FE1
Boutilier, RG1
West, TG1
Webber, DM1
Pogson, GH1
Mesa, KA1
Wells, J1
Wells, MJ1
Leach, RM1
Hill, HM1
Snetkov, VA1
Robertson, TP1
Ward, JP1
Santini, G1
Bruschini, C1
Pazzagli, L1
Pieraccini, G1
Moneti, G1
Chelazzi, G1
Van Cappellen Van Walsum, AM1
Jongsma, HW1
Wevers, RA1
Nijhuis, JG1
Crevels, J1
Engelke, UF1
De Abreu, RA1
Moolenaar, SH1
Oeseburg, B1
Nijland, R1
Corbucci, GG1
Menichetti, A1
Cogliatti, A1
Nicoli, P1
Ruvolo, C1
Juretschke, HP1
Kamp, G1
Wagner, KR2
Kleinholz, M1
Myers, RE2
Hohl, C1
Oestreich, R1
Rösen, P1
Wiesner, R1
Grieshaber, M1
Bonventre, JV1
Cheung, JY1

Reviews

4 reviews available for succinic acid and Anoxemia

ArticleYear
[Molecular mechanisms for hypoxia development and adaptation to it. Part I].
    Arkhiv patologii, 2021, Volume: 83, Issue:3

    Topics: Humans; Hypoxia; Signal Transduction; Succinic Acid

2021
[Molecular mechanisms of hypoxia and adaptation to it. Part II].
    Arkhiv patologii, 2021, Volume: 83, Issue:3

    Topics: Humans; Hypoxia; Succinates; Succinic Acid

2021
Autologous cord blood in children with cerebral palsy: a review.
    International journal of molecular sciences, 2019, May-16, Volume: 20, Issue:10

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Brain Diseases; Brain Injuries; Carnitine; Cerebral Pal

2019
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis.
    Biochimica et biophysica acta, 2016, Volume: 1857, Issue:8

    Topics: Carcinogenesis; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1,

2016

Trials

1 trial available for succinic acid and Anoxemia

ArticleYear
Metabolic aspects of acute tissue hypoxia during extracorporeal circulation and their modification induced by L-carnitine treatment.
    International journal of clinical pharmacology research, 1992, Volume: 12, Issue:3

    Topics: Bicarbonates; Carnitine; Double-Blind Method; Extracorporeal Circulation; Female; Fumarates; Humans;

1992

Other Studies

55 other studies available for succinic acid and Anoxemia

ArticleYear
Watercore Pear Fruit Respiration Changed and Accumulated γ-Aminobutyric Acid (GABA) in Response to Inner Hypoxia Stress.
    Genes, 2022, 05-30, Volume: 13, Issue:6

    Topics: Fruit; gamma-Aminobutyric Acid; Hypoxia; Pyrus; Respiration; Succinic Acid

2022
Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury.
    Redox biology, 2022, Volume: 54

    Topics: Animals; Disease Models, Animal; Energy Metabolism; Hypoxia; Ischemia; Lactates; Mice; Myocytes, Car

2022
The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions.
    Cells, 2022, 07-13, Volume: 11, Issue:14

    Topics: Animals; Cell Membrane; Endoplasmic Reticulum; Hypoxia; Mice; Receptors, G-Protein-Coupled; Succinat

2022
[Succinate salts in solving the «oxygen paradox» of reperfusion].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:9

    Topics: Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Oxygen; Reactive Oxygen Species; Reperfu

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
The Role of Mitochondrial Enzymes, Succinate-Coupled Signaling Pathways and Mitochondrial Ultrastructure in the Formation of Urgent Adaptation to Acute Hypoxia in the Myocardium.
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Animals; Hypoxia; Mitochondria, Heart; Myocardium; Rats; Signal Transduction; Succinic Acid; Vascula

2022
Two decades of research on anoxia tolerance - mitochondria, -omics and physiological diversity.
    The Journal of experimental biology, 2023, 04-01, Volume: 226, Issue:7

    Topics: Animals; Brain; Hypoxia; Mitochondria; Reactive Oxygen Species; Succinates; Succinic Acid; Vertebrat

2023
Low production of mitochondrial reactive oxygen species after anoxia and reoxygenation in turtle hearts.
    The Journal of experimental biology, 2023, 05-01, Volume: 226, Issue:9

    Topics: Animals; Hydrogen Peroxide; Hypoxia; Mammals; Mitochondria, Heart; Reactive Oxygen Species; Succinat

2023
Puerarin-Tanshinone IIA Suppresses atherosclerosis inflammatory plaque via targeting succinate/HIF-1α/IL-1β axis.
    Journal of ethnopharmacology, 2023, Dec-05, Volume: 317

    Topics: Animals; Atherosclerosis; Hypoxia; Interleukin-1beta; Mice; Molecular Docking Simulation; Plaque, At

2023
Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage.
    Science advances, 2023, 06-16, Volume: 9, Issue:24

    Topics: Animals; Endothelial Cells; Hemorrhage; Hypoxia; Lipid Metabolism; Rats; Succinates; Succinic Acid

2023
Role of succinate in airway epithelial cell regulation following traumatic lung injury.
    JCI insight, 2023, 09-22, Volume: 8, Issue:18

    Topics: Animals; Epithelial Cells; Humans; Hypoxia; Inflammation; Lung; Lung Injury; Mice; Respiratory Distr

2023
Succinate-mediated reactive oxygen species production in the anoxia-tolerant epaulette (
    Biology letters, 2023, Volume: 19, Issue:10

    Topics: Animals; Floors and Floorcoverings; Hypoxia; Oxygen; Reactive Oxygen Species; Sharks; Succinic Acid

2023
Tissue-Specific Peculiarities of Vibration-Induced Hypoxia in Rabbit Liver and Kidney.
    Bulletin of experimental biology and medicine, 2019, Volume: 167, Issue:5

    Topics: 2,4-Dinitrophenol; Animals; Electron Transport; Flavin-Adenine Dinucleotide; Hypoxia; Kidney; Liver;

2019
Effects of hypoxia and reoxygenation on intermediary metabolite homeostasis of marine bivalves Mytilus edulis and Crassostrea gigas.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2020, Volume: 242

    Topics: Aerobiosis; Amino Acids; Animals; Crassostrea; Energy Metabolism; gamma-Aminobutyric Acid; Homeostas

2020
H
    American journal of physiology. Regulatory, integrative and comparative physiology, 2020, 07-01, Volume: 319, Issue:1

    Topics: Adenosine Triphosphate; Animals; Chickens; Electron Transport; Energy Metabolism; Erythrocytes; Fema

2020
Krebs cycle metabolites and preferential succinate oxidation following neonatal hypoxic-ischemic brain injury in mice.
    Pediatric research, 2018, Volume: 83, Issue:2

    Topics: Animals; Animals, Newborn; Chromatography, High Pressure Liquid; Citric Acid Cycle; Electrons; Hydro

2018
Suppression of reactive oxygen species generation in heart mitochondria from anoxic turtles: the role of complex I
    The Journal of experimental biology, 2018, 04-25, Volume: 221, Issue:Pt 8

    Topics: Adaptation, Physiological; Animals; Electron Transport Complex I; Glucosides; Hypoxia; Mitochondria,

2018
Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury.
    Scientific reports, 2019, 02-26, Volume: 9, Issue:1

    Topics: Animals; Heart; Hypoxia; Myocardium; Reactive Oxygen Species; Reperfusion Injury; Succinic Acid; Tur

2019
[Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:21

    Topics: Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cell Survival; Cells, Cultured; Female; Humans; Hypoxia

2013
[THE ENERGY FUNCTION OF RAT CARDIAC MITOCHONDRIA UNDER ARTIFICIAL HYPOBIOSIS].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2015, Volume: 61, Issue:2

    Topics: Animals; Animals, Outbred Strains; Body Temperature; Carbon Dioxide; Cell Fractionation; Electron Tr

2015
Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression.
    Blood, 2016, 05-26, Volume: 127, Issue:21

    Topics: Cell Survival; Gene Expression Regulation; Germ-Line Mutation; Humans; Hypoxia; Hypoxia-Inducible Fa

2016
Effect of cerebronorm on energy metabolism and lipid peroxidation in rat brain during hypoxia.
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:5

    Topics: Animals; Brain; Energy Metabolism; Hypoxia; Inosine Diphosphate; Lipid Peroxidation; Male; Mitochond

2007
Enhanced leukocyte HIF-1alpha and HIF-1 DNA binding in humans after rapid ascent to 4300 m.
    Free radical biology & medicine, 2009, Jun-01, Volume: 46, Issue:11

    Topics: Adult; Altitude; Biomarkers; Dinoprost; DNA; Female; Free Radicals; Glutathione; Heart Rate; Humans;

2009
[Supply and demand: the influence of energy metabolism on angiogenesis].
    Medecine sciences : M/S, 2009, Volume: 25, Issue:4

    Topics: Animals; Diabetic Retinopathy; Energy Metabolism; Humans; Hypoxia; Infant, Newborn; Injections; Isch

2009
Effects of succinic and glutamic acid combination on energy metabolism in the liver of mice under conditions of hypoxia.
    Bulletin of experimental biology and medicine, 2009, Volume: 147, Issue:3

    Topics: Animals; Drug Combinations; Energy Metabolism; Glutamic Acid; Hypoxia; Lipid Peroxidation; Liver; Ma

2009
Glycolysis and the tricarboxylic acid cycle are linked by alanine aminotransferase during hypoxia induced by waterlogging of Lotus japonicus.
    Plant physiology, 2010, Volume: 152, Issue:3

    Topics: Adenosine Triphosphate; Alanine; Alanine Transaminase; Citric Acid Cycle; Fermentation; Gene Express

2010
Mitochondrial complex II prevents hypoxic but not calcium- and proapoptotic Bcl-2 protein-induced mitochondrial membrane potential loss.
    The Journal of biological chemistry, 2010, Aug-20, Volume: 285, Issue:34

    Topics: Adenosine Triphosphate; Animals; Calcium; Electron Transport Complex II; Humans; Hypoxia; Membrane P

2010
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry.
    Cell cycle (Georgetown, Tex.), 2011, Sep-01, Volume: 10, Issue:17

    Topics: Citric Acid Cycle; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regul

2011
Physiological responses to self-induced burrowing and metabolic rate depression in the ocean quahog Arctica islandica.
    The Journal of experimental biology, 2011, Dec-15, Volume: 214, Issue:Pt 24

    Topics: Animals; Antioxidants; Basal Metabolism; Bivalvia; Catalase; Gills; Hypoxia; Oxidative Stress; Oxyge

2011
Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity.
    The Biochemical journal, 2012, Jul-15, Volume: 445, Issue:2

    Topics: 3T3 Cells; Adipocytes; Animals; Blotting, Western; Cell Survival; Citric Acid Cycle; Electrophoresis

2012
Antihypoxic and antioxidant effects of exogenous succinic acid and aminothiol succinate-containing antihypoxants.
    Bulletin of experimental biology and medicine, 2012, Volume: 153, Issue:3

    Topics: Animals; Antioxidants; Guanylthiourea; Hypoxia; Lipid Peroxidation; Male; Rats; Rats, Wistar; Succin

2012
SAGE surveys C. elegans carbohydrate metabolism: evidence for an anaerobic shift in the long-lived dauer larva.
    Mechanisms of ageing and development, 2003, Volume: 124, Issue:7

    Topics: Alcohols; Anaerobiosis; Animals; Base Sequence; Caenorhabditis elegans; Carbohydrate Metabolism; Cit

2003
Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: Animals; Blotting, Northern; Blotting, Western; DNA-Binding Proteins; Down-Regulation; Feedback, Phy

2003
[Tricarboxylic acid cycle in energy metabolism and antioxidant cell defense in acute hypoxia].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2003, Volume: 49, Issue:3

    Topics: Acute Disease; Animals; Antioxidants; Catalase; Cholinergic Antagonists; Citric Acid Cycle; Disease

2003
Comparison between the effects of glucose and sodium succinate on the in vitro release of histamine from guinea-pig and rat lung tissue.
    Acta physiologica Scandinavica, 1962, Volume: 56

    Topics: Anaphylaxis; Animals; Glucose; Guinea Pigs; Histamine; Histamine Release; Hypoxia; In Vitro Techniqu

1962
[Succinic acid and anoxia].
    Prensa medica argentina, 1952, Jun-06, Volume: 39, Issue:23

    Topics: Hypoxia; Succinates; Succinic Acid

1952
Production of organic acids by Corynebacterium glutamicum under oxygen deprivation.
    Applied microbiology and biotechnology, 2005, Volume: 68, Issue:4

    Topics: Corynebacterium glutamicum; Hypoxia; Lactic Acid; Succinic Acid

2005
Coenzyme q10 confers cardiovascular protection against acute mevinphos intoxication by ameliorating bioenergetic failure and hypoxia in the rostral ventrolateral medulla of the rat.
    Shock (Augusta, Ga.), 2005, Volume: 23, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Cardiovascular System; Coenzymes; Electron Transport

2005
[The modification of nitric oxide production by exogenous substrates of Krebs cycle during acute hypoxia].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2005, Volume: 51, Issue:4

    Topics: Acute Disease; Animals; Biogenic Polyamines; Citric Acid Cycle; Erythrocytes; Hypoxia; Ketoglutaric

2005
Effect of ubiquinone-10 and succinic acid on functional characteristics of erythrocytes in rats with epinephrine toxemia.
    Bulletin of experimental biology and medicine, 2006, Volume: 141, Issue:4

    Topics: Animals; Epinephrine; Erythrocyte Aggregation; Erythrocytes; Female; Hypoxia; Lipid Peroxidation; Mo

2006
Transcriptional regulation of pyruvate kinase and phosphoenolpyruvate carboxykinase in the adductor muscle of the oyster Crassostrea gigas during prolonged hypoxia.
    Journal of experimental zoology. Part A, Ecological genetics and physiology, 2007, Jul-01, Volume: 307, Issue:7

    Topics: Amino Acid Sequence; Animals; Base Sequence; Crassostrea; Digestive System; DNA Primers; Gene Expres

2007
Direct sampling of organisms from the field and knowledge of their phenotype: key recommendations for environmental metabolomics.
    Environmental science & technology, 2007, May-01, Volume: 41, Issue:9

    Topics: Acetoacetates; Amino Acids; Animals; Betaine; Female; Hypoxia; Male; Muscles; Mytilus; Phenotype; Pi

2007
Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis.
    The Journal of experimental biology, 2007, Volume: 210, Issue:Pt 13

    Topics: Amino Acids; Animals; Embryo, Nonmammalian; gamma-Aminobutyric Acid; Hypoxia; Killifishes; Lactic Ac

2007
Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface.
    ACS chemical biology, 2007, Aug-17, Volume: 2, Issue:8

    Topics: Base Sequence; Cell Death; DNA; Hypoxia; Hypoxia-Inducible Factor 1; Models, Molecular; Nucleic Acid

2007
[Mitochondrial respiration and oxidative phosphorylation in the kidneys of white rats under conditions of hemic hypoxia and the use of different suture materials].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 1998, Volume: 44, Issue:1-2

    Topics: Animals; Female; Hypoxia; Kidney; Male; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation

1998
Generation of superoxide anion by mitochondria and impairment of their functions during anoxia and reoxygenation in vitro.
    Free radical biology & medicine, 1998, Volume: 25, Issue:9

    Topics: Adenosine Diphosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Respiration

1998
The protective effects of hypoxia-induced hypometabolism in the Nautilus.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2000, Volume: 170, Issue:4

    Topics: Acid-Base Equilibrium; Adaptation, Physiological; Animals; Arginine; Basal Metabolism; Carbon Dioxid

2000
[State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2001, Volume: 47, Issue:3

    Topics: Adenosine Diphosphate; Animals; Arginine; Calcium; Enzyme Inhibitors; Hypoxia; Ketoglutaric Acids; M

2001
Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor.
    The Journal of physiology, 2001, Oct-01, Volume: 536, Issue:Pt 1

    Topics: Animals; Antimetabolites; Cyanides; Deoxyglucose; Electron Transport; Electron Transport Complex III

2001
Metabolic responses of the limpet Patella caerulea (L.) to anoxia and dehydration.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2001, Volume: 130, Issue:1

    Topics: Acetates; Adaptation, Physiological; Alanine; Animals; Aspartic Acid; Dehydration; Hypoxia; Mollusca

2001
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
    Pediatric research, 2002, Volume: 52, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Femal

2002
In vivo 13C-NMR studies on the metabolism of the lugworm Arenicola marina.
    European journal of biochemistry, 1990, Oct-05, Volume: 193, Issue:1

    Topics: Alanine; Animals; Carbon; Glucose; Glycogen; Hydrogen-Ion Concentration; Hypoxia; Magnetic Resonance

1990
Delayed neurologic deterioration following anoxia: brain mitochondrial and metabolic correlates.
    Journal of neurochemistry, 1989, Volume: 52, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Glucose; Brain; Carbon Dioxide; Cats;

1989
Hyperglycemia preserves brain mitochondrial respiration during anoxia.
    Journal of neurochemistry, 1986, Volume: 47, Issue:5

    Topics: Animals; Brain; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cats; Glutamates; Glutamic Acid;

1986
Evidence for succinate production by reduction of fumarate during hypoxia in isolated adult rat heart cells.
    Archives of biochemistry and biophysics, 1987, Volume: 259, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Chromatography, High Pressure Liquid; Deoxyglucose;

1987
Effects of metabolic acidosis on viability of cells exposed to anoxia.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 1

    Topics: Acidosis; Adenine Nucleotides; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Cytosol; Fem

1985