succinic acid has been researched along with Alzheimer Disease in 2 studies
Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Tapias, V | 1 |
| Acosta, D | 1 |
| Xu, H | 1 |
| Chen, H | 1 |
| Bhawal, R | 1 |
| Anderson, ET | 1 |
| Ivanova, E | 1 |
| Lin, H | 1 |
| Sagdullaev, BT | 1 |
| Chen, J | 1 |
| Klein, WL | 1 |
| Viola, KL | 1 |
| Gandy, S | 1 |
| Haroutunian, V | 1 |
| Beal, MF | 1 |
| Eliezer, D | 1 |
| Zhang, S | 1 |
| Gibson, GE | 1 |
| Redjems-Bennani, N | 1 |
| Jeandel, C | 1 |
| Lefebvre, E | 1 |
| Blain, H | 1 |
| Vidailhet, M | 1 |
| Guéant, JL | 1 |
2 other studies available for succinic acid and Alzheimer Disease
| Article | Year |
|---|---|
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Autopsy; Brain; Cas | 2022 |
Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from Alzheimer patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrospinal Fluid; Citric Acid Cycle; Female; Fumarate | 1998 |