Page last updated: 2024-10-20

succinic acid and Acute Lung Injury

succinic acid has been researched along with Acute Lung Injury in 3 studies

Succinic Acid: A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
succinic acid : An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.

Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of dehydroandrographolide succinate (DAS) on oxidative stress and induced nitric oxide synthase (iNOS) expression in a mouse model of lipopolysaccharide (LPS)-induced acute lung injury."7.78[Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS]. ( Guan, X; Wang, D; Zhang, W; Zhu, T, 2012)
"To investigate the effect of dehydroandrographolide succinate (DAS) on oxidative stress and induced nitric oxide synthase (iNOS) expression in a mouse model of lipopolysaccharide (LPS)-induced acute lung injury."3.78[Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS]. ( Guan, X; Wang, D; Zhang, W; Zhu, T, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Wang, YH1
Yan, ZZ1
Luo, SD1
Hu, JJ1
Wu, M1
Zhao, J1
Liu, WF1
Li, C1
Liu, KX1
Bongers, KS1
Stringer, KA1
Dickson, RP1
Zhu, T1
Guan, X1
Zhang, W1
Wang, D1

Other Studies

3 other studies available for succinic acid and Acute Lung Injury

ArticleYear
Gut microbiota-derived succinate aggravates acute lung injury after intestinal ischaemia/reperfusion in mice.
    The European respiratory journal, 2023, Volume: 61, Issue:2

    Topics: Acute Lung Injury; Animals; Gastrointestinal Microbiome; Ischemia; Mice; Mice, Inbred C57BL; Phospha

2023
The gut microbiome in ARDS: from the "whether" and "what" to the "how".
    The European respiratory journal, 2023, Volume: 61, Issue:2

    Topics: Acute Lung Injury; Animals; Gastrointestinal Microbiome; Ischemia; Mice; Respiratory Distress Syndro

2023
[Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:9

    Topics: Acute Lung Injury; Animals; Diterpenes; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Nitric

2012