succimer and Trypanosomiasis--African

succimer has been researched along with Trypanosomiasis--African* in 1 studies

Other Studies

1 other study(ies) available for succimer and Trypanosomiasis--African

Article	Year
Chemotherapy of trypanosomiasis: the potentiation of antimonial compounds by difluoromethylornithine (DFMO). Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:2 The currently available anti-leishmanial antimonial drugs, together with other antimony compounds were individually tested, in combination with difluoromethylornithine (DFMO), against experimental murine trypanosomiasis with central nervous system involvement. Satisfactory cure rates could be achieved using a combination treatment of DFMO with most of these anti-leishmanial drugs, but in general, only when they were administered at least twice daily. Of the compounds tested, the most effective was antimony dimercaptosuccinate (Astiban). Topics: Animals; Antimony; Antimony Sodium Gluconate; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Meglumine; Meglumine Antimoniate; Mice; Organometallic Compounds; Succimer; Tartrates; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1991

Article

Year

Chemotherapy of trypanosomiasis: the potentiation of antimonial compounds by difluoromethylornithine (DFMO).

Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:2

The currently available anti-leishmanial antimonial drugs, together with other antimony compounds were individually tested, in combination with difluoromethylornithine (DFMO), against experimental murine trypanosomiasis with central nervous system involvement. Satisfactory cure rates could be achieved using a combination treatment of DFMO with most of these anti-leishmanial drugs, but in general, only when they were administered at least twice daily. Of the compounds tested, the most effective was antimony dimercaptosuccinate (Astiban).

Topics: Animals; Antimony; Antimony Sodium Gluconate; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Meglumine; Meglumine Antimoniate; Mice; Organometallic Compounds; Succimer; Tartrates; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1991