Page last updated: 2024-08-23

substance p and Tendinopathy

substance p has been researched along with Tendinopathy in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.76)18.2507
2000's6 (28.57)29.6817
2010's12 (57.14)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
An, HJ; Baek, M; Choi, J; Choi, S; Han, SH; Jeong, Y; Kim, IS; Ko, KR; Kwak, EB; Lee, J; Lee, S1
Ahn, W; Baek, M; Han, SH; Jeong, Y; Kim, DK; Kim, H; Lee, HH; Lee, S; Oh, SY1
Ahn, H; Ahn, T; Baik, L; Byun, SE; Choi, W; Choi, Y; Ding, C; Han, SH; Kim, J; Lee, S; Song, J; Ting, K; Ward, S1
Backman, LJ; Chen, J; El-Habta, R; Pingel, J1
Rees, JD; Scott, A; Stride, M1
Tang, K; Zhou, B; Zhou, Y2
Alfredson, H; Andersson, G; Christensen, J1
Danielson, P1
Amin, M; Amin, S; Barbe, MF; Barr, AE; Fedorczyk, JM; Gao, HG; Litvin, J; Rani, S1
Chan, KM; Chan, LS; Fu, SC; Lui, PP1
Andersson, G; Backman, LJ; Danielson, P; Forsgren, S; Lorentzon, R; Scott, A1
Andersson, G; Backman, LJ; Danielson, P; Forsgren, S; Wennstig, G1
Ackermann, PW; Bahr, R; Frihagen, F; Lian, O; Schizas, N; Weiss, R1
Backman, LJ; Danielson, P; Fong, G; Hart, DA; McCormack, B; Scott, A1
Riley, G1
Hofstädter, F; Lerch, K; Schubert, TE; Straub, RH; Weidler, C1
Ackermann, PW; Bahr, R; Dahl, J; Engebretsen, L; Frihagen, F; Lian, Ø1
Alfredson, H; Andersson, G; Danielson, P; Forsgren, S2
Hart, DA; Kydd, A; Reno, C1

Reviews

2 review(s) available for substance p and Tendinopathy

ArticleYear
Tendons--time to revisit inflammation.
    British journal of sports medicine, 2014, Volume: 48, Issue:21

    Topics: Anti-Inflammatory Agents; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Humans; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Musculoskeletal Pain; Neovascularization, Pathologic; Substance P; Tendinopathy; Tendons; Tumor Necrosis Factor-alpha

2014
Chronic tendon pathology: molecular basis and therapeutic implications.
    Expert reviews in molecular medicine, 2005, Mar-24, Volume: 7, Issue:5

    Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Collagen; Cumulative Trauma Disorders; Extracellular Matrix; Glycoproteins; Humans; Matrix Metalloproteinases; Middle Aged; Neuropeptides; Proteoglycans; Rupture; Substance P; Tendinopathy; Tendon Injuries; Tendons

2005

Other Studies

19 other study(ies) available for substance p and Tendinopathy

ArticleYear
Substance P Inhibitor Promotes Tendon Healing in a Collagenase-Induced Rat Model of Tendinopathy.
    The American journal of sports medicine, 2022, Volume: 50, Issue:13

    Topics: Achilles Tendon; Alcian Blue; Animals; Collagenases; Humans; Interleukin-6; Rats; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tendinopathy

2022
Sustained Exposure of Substance P Causes Tendinopathy.
    International journal of molecular sciences, 2020, Nov-16, Volume: 21, Issue:22

    Topics: Achilles Tendon; Animals; Cells, Cultured; Humans; Rats; Rats, Sprague-Dawley; Substance P; Tendinopathy

2020
The Implication of Substance P in the Development of Tendinopathy: A Case Control Study.
    International journal of molecular sciences, 2017, Jun-09, Volume: 18, Issue:6

    Topics: Biomarkers; Cell Proliferation; Cell Survival; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation; Humans; RNA, Messenger; Substance P; Tendinopathy; Tendons

2017
Tendinosis-like changes in denervated rat Achilles tendon.
    BMC musculoskeletal disorders, 2018, Nov-30, Volume: 19, Issue:1

    Topics: Achilles Tendon; Animals; Biopsy; Denervation; Disease Models, Animal; Female; Humans; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sciatic Nerve; Substance P; Tendinopathy

2018
The effects of substance P on pluripotent tendon cells: an in vitro and in vivo study.
    Journal of musculoskeletal & neuronal interactions, 2014, Volume: 14, Issue:3

    Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Hindlimb; In Vitro Techniques; Male; Neurotransmitter Agents; Pluripotent Stem Cells; Rats; Rats, Sprague-Dawley; Substance P; Tendinopathy; Tendons

2014
Protease-activated receptors in the Achilles tendon-a potential explanation for the excessive pain signalling in tendinopathy.
    Molecular pain, 2015, Mar-17, Volume: 11

    Topics: Achilles Tendon; Adult; Aged; Female; Humans; Immunohistochemistry; Male; Middle Aged; Pain; Receptors, Proteinase-Activated; Substance P; Tendinopathy

2015
The effects of substance p on tendinopathy are dose-dependent: an in vitro and in vivo model study.
    The journal of nutrition, health & aging, 2015, Volume: 19, Issue:5

    Topics: Animals; Cell Differentiation; Cell Proliferation; Collagen Type II; Disease Models, Animal; In Vitro Techniques; Male; Patellar Ligament; PPAR gamma; Rats; Rats, Sprague-Dawley; Stem Cells; Substance P; Tendinopathy; Tendons

2015
Reviving the "biochemical" hypothesis for tendinopathy: new findings suggest the involvement of locally produced signal substances.
    British journal of sports medicine, 2009, Volume: 43, Issue:4

    Topics: Acetylcholine; Catecholamines; Humans; Signal Transduction; Substance P; Tendinopathy

2009
Exposure-dependent increases in IL-1beta, substance P, CTGF, and tendinosis in flexor digitorum tendons with upper extremity repetitive strain injury.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:3

    Topics: Animals; Connective Tissue Growth Factor; Cumulative Trauma Disorders; Disease Progression; Female; Fibroblasts; Forelimb; Hand Strength; Immunohistochemistry; Interleukin-1beta; Macrophages; Rats; Rats, Sprague-Dawley; Substance P; Tendinopathy; Tendons; Time Factors

2010
Expression of sensory neuropeptides in tendon is associated with failed healing and activity-related tendon pain in collagenase-induced tendon injury.
    The American journal of sports medicine, 2010, Volume: 38, Issue:4

    Topics: Animals; Calcinosis; Calcitonin Gene-Related Peptide; Chondrocytes; Collagenases; Gait; Male; Pain; Patellar Ligament; Rats; Rats, Sprague-Dawley; Substance P; Tendinopathy; Wound Healing

2010
Substance P accelerates hypercellularity and angiogenesis in tendon tissue and enhances paratendinitis in response to Achilles tendon overuse in a tendinopathy model.
    British journal of sports medicine, 2011, Volume: 45, Issue:13

    Topics: Achilles Tendon; Administration, Cutaneous; Animals; Cell Proliferation; Cumulative Trauma Disorders; Female; Neovascularization, Pathologic; Neurotransmitter Agents; Physical Conditioning, Animal; Rabbits; Random Allocation; Receptors, Neurokinin-1; Substance P; Tendinopathy

2011
Endogenous substance P production in the Achilles tendon increases with loading in an in vivo model of tendinopathy-peptidergic elevation preceding tendinosis-like tissue changes.
    Journal of musculoskeletal & neuronal interactions, 2011, Volume: 11, Issue:2

    Topics: Achilles Tendon; Animals; Disease Models, Animal; Female; Neuropeptides; Rabbits; Stress, Mechanical; Substance P; Tendinopathy; Up-Regulation; Weight-Bearing

2011
Glutamate receptors in tendinopathic patients.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2012, Volume: 30, Issue:9

    Topics: Adult; Female; Humans; Male; Nerve Tissue Proteins; Patellar Ligament; Phosphorylation; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance P; Tendinopathy; Young Adult

2012
Substance P enhances collagen remodeling and MMP-3 expression by human tenocytes.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2013, Volume: 31, Issue:1

    Topics: Achilles Tendon; Actins; Biopsy; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Fibroblasts; Gene Expression; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 3; Neurotransmitter Agents; Primary Cell Culture; Receptors, Neurokinin-1; Substance P; Tendinopathy; Tissue Inhibitor of Metalloproteinase-1; Weight-Bearing

2013
Achilles tendinosis is associated with sprouting of substance P positive nerve fibres.
    Annals of the rheumatic diseases, 2005, Volume: 64, Issue:7

    Topics: Achilles Tendon; Case-Control Studies; Female; Granulation Tissue; Hemosiderosis; Humans; Immunohistochemistry; Male; Middle Aged; Nerve Fibers; Neuralgia; Neurons, Afferent; Rupture, Spontaneous; Substance P; Tendinopathy

2005
Pronociceptive and antinociceptive neuromediators in patellar tendinopathy.
    The American journal of sports medicine, 2006, Volume: 34, Issue:11

    Topics: Adult; Biopsy; Case-Control Studies; Humans; Immunohistochemistry; Nerve Fibers; Patellar Ligament; Substance P; Tendinopathy; Tyrosine 3-Monooxygenase

2006
Nerve-related characteristics of ventral paratendinous tissue in chronic Achilles tendinosis.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2007, Volume: 15, Issue:10

    Topics: Achilles Tendon; Adult; Aged; Antibodies; Biopsy; Calcitonin Gene-Related Peptide; Chronic Disease; Female; Humans; Male; Middle Aged; Nerve Fibers; Receptors, Adrenergic, alpha-1; Receptors, Neurokinin-1; Substance P; Tendinopathy; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase

2007
Presence of substance P and the neurokinin-1 receptor in tenocytes of the human Achilles tendon.
    Regulatory peptides, 2008, Oct-09, Volume: 150, Issue:1-3

    Topics: Achilles Tendon; Adult; Aged; Case-Control Studies; Female; Humans; Immunohistochemistry; In Situ Hybridization; Male; Middle Aged; Neurotransmitter Agents; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tendinopathy

2008
Gender and pregnancy affect neuropeptide responses of the rabbit Achilles tendon.
    Clinical orthopaedics and related research, 1999, Issue:365

    Topics: Achilles Tendon; Animals; Calcitonin Gene-Related Peptide; Cumulative Trauma Disorders; Cyclooxygenase Inhibitors; Endopeptidases; Female; Growth Substances; Inflammation Mediators; Interleukin-1; Male; Muscular Diseases; Nitric Oxide Synthase; Pregnancy; Pregnancy, Animal; Protease Inhibitors; Rabbits; RNA, Messenger; Sex Factors; Substance P; Tendinopathy; Transcription, Genetic

1999