substance p has been researched along with Substance Withdrawal Syndrome in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 19 (39.58) | 18.7374 |
1990's | 15 (31.25) | 18.2507 |
2000's | 12 (25.00) | 29.6817 |
2010's | 1 (2.08) | 24.3611 |
2020's | 1 (2.08) | 2.80 |
Authors | Studies |
---|---|
Hnasko, TS; Khom, S; Roberto, M; Steinkellner, T | 1 |
Dani, JA; Dao, DQ; De Biasi, M; Perez, EE; Teng, Y | 1 |
Botros, M; Carlsson, A; Fransson, R; Gordh, T; Hallberg, M; Nyberg, F; Sandström, A; Zhou, Q | 1 |
Clark, JD; Li, X | 1 |
Frändberg, PA; Kindlundh, AM; Le Grevès, P; Nyberg, F; Zhou, Q | 1 |
Hallberg, M; Kindlundh, AM; Nyberg, F; Zhou, Q | 1 |
Kendig, JJ; Peters, MC; Sweitzer, SM; Wong, SME | 1 |
Ben Smail, D; Bussel, B; Denys, P; Hugeron, C | 1 |
Gu, G; Hua, XY; Kondo, I; Yaksh, TL | 1 |
Douglas, SD; Ho, WZ; Peng, JS; Wan, Q; Wang, X; Zhou, DJ | 1 |
Collier, HO; Tucker, JF | 1 |
Chahl, LA | 4 |
Carlson, HE; Damassa, DA; Gordon, J; Hershman, JM; Lamers, CB; Morley, JE; Shulkes, A; Walsh, JH; Wong, H; Yamada, T | 1 |
Louie, G; Tsou, K; Way, EL | 1 |
Bot, G; Chahl, LA | 1 |
Kreeger, JS; Larson, AA | 2 |
Girdlestone, D; Maldonado, R; Roques, BP | 1 |
Chahl, LA; Johnston, PA | 3 |
Chahl, LA; Kavanagh, CA | 1 |
Farzin, D; Zarrindast, MR | 1 |
Huang, W; Karlsson, K; Liu, Z; Nyberg, F; Ray, A; Zhou, Q | 1 |
Cappendijk, SL; Hurd, YL; Nylander, I; Terenius, L; van Ree, JM | 1 |
Arroyo, M; Baker, WA; Everitt, BJ | 1 |
Johansson, P; Karlsson, K; Kiuru, A; Le Grevés, M; Liu, Z; Nyberg, F; Zhou, Q | 1 |
Nyberg, F; Zhou, Q | 1 |
Jhamandas, K; Quirion, R; Sutak, M; Trang, T | 1 |
Gaytten, D; James, TA; Starr, MS | 1 |
Olley, JE; Pierce, TL; Tiong, GK | 1 |
Hutchison, WD; Morton, CR | 1 |
Hendry, IA; Hutchison, WD; Morton, CR | 1 |
Lu, YA; Tsou, K; Way, EL; Wu, SX | 1 |
Hendry, JS; Hong, JS; Rosecrans, JA | 1 |
Aronowski, J; Gumulka, SW; Konopinska, D; Luczak, M; Wleklik, M | 1 |
Bell, JA; Jaffe, JH | 1 |
Jaffe, JH; Sharpe, LG | 2 |
Chahl, LA; Thornton, CA | 1 |
Satoh, M; Takagi, H; Tamura, S; Ueda, H | 1 |
Tsou, K; Wang, FS | 1 |
Donnerer, J | 1 |
Stern, M; Stern, P | 1 |
Hadzović, J; Stern, P | 1 |
1 review(s) available for substance p and Substance Withdrawal Syndrome
Article | Year |
---|---|
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Morphine; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Pertussis Vaccine; Scopolamine; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Yohimbine | 1984 |
47 other study(ies) available for substance p and Substance Withdrawal Syndrome
Article | Year |
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Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala.
Topics: Adaptation, Physiological; Alcoholism; Animals; Central Amygdaloid Nucleus; Disease Models, Animal; Disease Susceptibility; gamma-Aminobutyric Acid; Gene Expression; Immunohistochemistry; Male; Rats; Receptors, Neurokinin-1; Signal Transduction; Substance P; Substance Withdrawal Syndrome | 2020 |
Nicotine enhances excitability of medial habenular neurons via facilitation of neurokinin signaling.
Topics: Action Potentials; Animals; Female; Habenula; Male; Mice; Mice, Inbred C57BL; Neurokinin B; Neurokinin-1 Receptor Antagonists; Neurons; Nicotine; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Receptors, Nicotinic; Signal Transduction; Substance P; Substance Withdrawal Syndrome | 2014 |
The C-terminal amidated analogue of the substance P (SP) fragment SP(1-7) attenuates the expression of naloxone-precipitated withdrawal in morphine dependent rats.
Topics: Animals; Antipsychotic Agents; Brain; Male; Morphine Dependence; Naloxone; Peptide Fragments; Phenazocine; Rats; Rats, Wistar; Substance P; Substance Withdrawal Syndrome | 2009 |
Hyperalgesia during opioid abstinence: mediation by glutamate and substance p.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Gene Expression; Genes, fos; Glutamic Acid; Histocytochemistry; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Morphine; Neurotransmitter Agents; Pain Measurement; Posterior Horn Cells; Reaction Time; Substance P; Substance Withdrawal Syndrome | 2002 |
Substance P(1-7) affects the expression of dopamine D2 receptor mRNA in male rat brain during morphine withdrawal.
Topics: Animals; Brain; Gene Expression Regulation; Male; Morphine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA, Messenger; Substance P; Substance Withdrawal Syndrome | 2003 |
The substance P (SP) heptapeptide fragment SP1-7 alters the density of dopamine receptors in rat brain mesocorticolimbic structures during morphine withdrawal.
Topics: Animals; Autoradiography; Brain; Male; Morphine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Substance P; Substance Withdrawal Syndrome | 2004 |
Hyperresponsiveness on washout of volatile anesthetics from isolated spinal cord compared to withdrawal from ethanol.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Electric Stimulation; Enzyme Inhibitors; Ethanol; Excitatory Postsynaptic Potentials; Glutamic Acid; Indoles; Maleimides; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Substance Withdrawal Syndrome | 2005 |
Pruritus after intrathecal baclofen withdrawal: A retrospective study.
Topics: Baclofen; GABA Agonists; Humans; Incidence; Infusion Pumps, Implantable; Injections, Spinal; Muscle Spasticity; Pruritus; Retrospective Studies; Substance P; Substance Withdrawal Syndrome | 2005 |
Resting and evoked spinal substance P release during chronic intrathecal morphine infusion: parallels with tolerance and dependence.
Topics: Animals; Cyclic AMP; Drug Tolerance; Injections, Spinal; Male; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Substance Withdrawal Syndrome | 2005 |
An in vitro model of morphine withdrawal manifests the enhancing effect on human immunodeficiency virus infection of human T lymphocytes through the induction of substance P.
Topics: Biphenyl Compounds; Gene Expression Regulation; HIV; HIV Infections; HIV Long Terminal Repeat; Humans; Jurkat Cells; Morphine; RNA, Messenger; Substance P; Substance Withdrawal Syndrome; T-Lymphocytes; Virus Replication | 2006 |
Contracture of guinea-pig ileum on withdrawal of methionine5-enkephalin is mediated by substance P.
Topics: Animals; Enkephalin, Methionine; Feedback; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Naloxone; Substance P; Substance Withdrawal Syndrome | 1983 |
Morphine addiction and withdrawal alters brain peptide concentrations.
Topics: Animals; Brain Chemistry; Hormones; Humans; Male; Morphine Dependence; Neurotensin; Peptides; Rats; Substance P; Substance Withdrawal Syndrome | 1980 |
Manifestations of gut opiate withdrawal contracture and its blockade by capsaicin.
Topics: Animals; Capsaicin; Digestive System; Electric Stimulation; Fatty Acids, Unsaturated; Guinea Pigs; Humans; Male; Muscle Contraction; Myenteric Plexus; Naloxone; Scopolamine; Serotonin; Serotonin Antagonists; Substance P; Substance Withdrawal Syndrome | 1982 |
Effects of pertussis toxin on behavioural responses of guinea-pigs to centrally administered substance P, quinpirole, carbachol, U-50,488H, morphine and morphine withdrawal.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Carbachol; Dopamine Agents; Ergolines; Female; Guinea Pigs; Injections, Intraventricular; Male; Morphine; Motor Activity; Naloxone; Pertussis Toxin; Pyrrolidines; Quinpirole; Receptors, Opioid, kappa; Substance P; Substance Withdrawal Syndrome; Virulence Factors, Bordetella | 1993 |
Substance P-(1-7), a substance P metabolite, inhibits withdrawal jumping in morphine-dependent mice.
Topics: Animals; Drug Interactions; Injections, Spinal; Male; Mice; Morphine; Morphine Dependence; Naloxone; Peptide Fragments; Substance P; Substance Withdrawal Syndrome | 1993 |
RP 67580, a selective antagonist of neurokinin-1 receptors, modifies some of the naloxone-precipitated morphine withdrawal signs in rats.
Topics: Analgesics; Animals; Cerebral Ventricles; Indoles; Injections, Intraventricular; Isoindoles; Male; Morphine; Motor Activity; Naloxone; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Reference Values; Stereotyped Behavior; Substance P; Substance Withdrawal Syndrome | 1993 |
Neurokinin-1, -2 and -3 receptors are candidates for a role in the opiate withdrawal response in guinea-pigs.
Topics: Animals; Cerebral Ventricles; Guinea Pigs; Injections, Intraventricular; Motor Activity; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Substance Withdrawal Syndrome | 1993 |
Effect of the nonpeptide NK-1 receptor antagonist CP-96,345 on the morphine withdrawal response of guinea-pigs.
Topics: Animals; Biphenyl Compounds; Cerebral Ventricles; Guinea Pigs; Hypnotics and Sedatives; Injections, Intraventricular; Morphine; Motor Activity; Naloxone; Neurokinin-1 Receptor Antagonists; Stereotyped Behavior; Substance P; Substance Withdrawal Syndrome | 1993 |
Effect of CP-96,345 on the [Met5]enkephalin washout withdrawal response of the guinea-pig isolated ileum.
Topics: Acetylcholine; Animals; Biphenyl Compounds; Enkephalin, Methionine; Female; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Substance P; Substance Withdrawal Syndrome | 1993 |
Nicotine attenuates naloxone-induced jumping behaviour in morphine-dependent mice.
Topics: Animals; Atropine; Behavior, Animal; Benzazepines; Hexamethonium; Male; Mecamylamine; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Nicotine; Phenoxybenzamine; Propranolol; Substance P; Substance Withdrawal Syndrome; Sulpiride | 1996 |
The substance P amino-terminal metabolite substance P(1-7), administered peripherally, prevents the development of acute morphine tolerance and attenuates the expression of withdrawal in mice.
Topics: Animals; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Male; Mice; Morphine Dependence; Naloxone; Peptide Fragments; Stereoisomerism; Substance P; Substance Withdrawal Syndrome | 1996 |
Alteration in the brain content of substance P (1-7) during withdrawal in morphine-dependent rats.
Topics: Animals; Brain; Male; Mice; Morphine; Morphine Dependence; Naloxone; Organ Specificity; Peptide Fragments; Pituitary Gland; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Substance Withdrawal Syndrome | 1998 |
A heroin-, but not a cocaine-expecting, self-administration state preferentially alters endogenous brain peptides.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Dynorphins; Enkephalins; Heroin; Injections, Intravenous; Male; Neuropeptides; Radioimmunoassay; Rats; Rats, Wistar; Self Administration; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1999 |
Cocaine self-administration in rats differentially alters mRNA levels of the monoamine transporters and striatal neuropeptides.
Topics: Animals; Brain Chemistry; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Enkephalins; Gene Expression; Injections, Intravenous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Rats; Rats, Inbred Strains; RNA, Messenger; Self Administration; Serotonin Plasma Membrane Transport Proteins; Substance P; Substance Withdrawal Syndrome; Symporters | 2000 |
Substance P endopeptidase-like activity is altered in various regions of the rat central nervous system during morphine tolerance and withdrawal.
Topics: Animals; Central Nervous System; Drug Tolerance; Male; Metalloendopeptidases; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Peptide Fragments; Rats; Rats, Sprague-Dawley; Substance P; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2001 |
Injection of substance P (SP) N-terminal fragment SP(1-7) into the ventral tegmental area modulates the levels of nucleus accumbens dopamine and dihydroxyphenylacetic acid in male rats during morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Extracellular Space; Male; Microdialysis; Morphine Dependence; Naloxone; Narcotic Antagonists; Neural Pathways; Nucleus Accumbens; Peptide Fragments; Presynaptic Terminals; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Substance P; Substance Withdrawal Syndrome; Up-Regulation; Ventral Tegmental Area | 2002 |
The role of spinal neuropeptides and prostaglandins in opioid physical dependence.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Injections, Spinal; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Neuropeptides; Pain Measurement; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Substance Withdrawal Syndrome | 2002 |
Behavioural depressant and antinociceptive properties of substance P in the mouse: possible implication of brain monoamines.
Topics: Analgesics; Animals; Behavior, Animal; Biogenic Amines; Brain; Corpus Striatum; Exploratory Behavior; Humans; In Vitro Techniques; Male; Mice; Morphine; Motor Activity; Substance P; Substance Withdrawal Syndrome | 1978 |
Sub-chronic exposure to opiates in the rat: effects on brain levels of substance P and calcitonin gene-related peptide during dependence and withdrawal.
Topics: Animals; Brain Chemistry; Calcitonin Gene-Related Peptide; Female; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Radioimmunoassay; Rats; Substance P; Substance Withdrawal Syndrome | 1992 |
Release of sensory neuropeptides in the cat spinal cord during morphine withdrawal.
Topics: Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Cats; Morphine; Naloxone; Neuropeptides; Nociceptors; Spinal Cord; Substance P; Substance Withdrawal Syndrome | 1990 |
Morphine produces release of substance P-like immunoreactivity from guinea-pig central nervous system.
Topics: Animals; Central Nervous System; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naloxone; Radioimmunoassay; Receptors, Opioid; Substance P; Substance Withdrawal Syndrome | 1990 |
Tachykinin antagonists inhibit the morphine withdrawal response in guinea-pigs.
Topics: Analgesics; Animals; Behavior, Animal; Female; Guinea Pigs; Injections, Intraventricular; Locomotion; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Peptide Fragments; Substance P; Substance Withdrawal Syndrome; Tachykinins | 1991 |
Intraspinal release of substance P and calcitonin gene-related peptide during opiate dependence and withdrawal.
Topics: Animals; Calcitonin Gene-Related Peptide; Cats; Immunologic Techniques; Morphine; Naloxone; Neurons; Reference Values; Spinal Cord; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders | 1991 |
Block of the hyoscine-resistant opiate withdrawal contracture of ileum by a new substance P antagonist [D-Arg1,D-Phe5,D- Trp7,9,Leu 11]substance P.
Topics: Animals; Drug Resistance; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Narcotics; Scopolamine; Substance P; Substance Withdrawal Syndrome | 1985 |
The properties of the clonidine withdrawal response of guinea-pig isolated ileum.
Topics: Animals; Atropine; Clonidine; Drug Interactions; Enkephalin, Methionine; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Muscle Contraction; Norepinephrine; Phentolamine; Substance P; Substance Withdrawal Syndrome; Yohimbine | 1985 |
Biphasic effects of chronic nicotine treatment on hypothalamic immunoreactive beta-endorphin in the mouse.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Methionine; Humans; Hypothalamus; Male; Mice; Mice, Inbred ICR; Neurotensin; Nicotine; Pituitary Gland; Substance P; Substance Withdrawal Syndrome | 1985 |
Modification of morphine withdrawal: effect of tuftsin, [Lys4]-tuftsinyltuftsin, tetrapeptide fragment (1-4) of substance P and its amide.
Topics: Adjuvants, Immunologic; Animals; Male; Morphine; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Substance Withdrawal Syndrome; Tuftsin | 1985 |
Electrophysiological evidence for a presynaptic mechanism of morphine withdrawal in the neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Capsaicin; In Vitro Techniques; Membrane Potentials; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Substance Withdrawal Syndrome; Synapses | 1986 |
Withdrawal responses of guinea-pig isolated ileum following brief exposure to opiates and opioid peptides.
Topics: Animals; Benzomorphans; Buprenorphine; Cyclazocine; Endorphins; Ethylketocyclazocine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Narcotics; Substance P; Substance Withdrawal Syndrome | 1986 |
Neonatal capsaicin modifies morphine withdrawal signs in the rat.
Topics: Animals; Animals, Newborn; Capsaicin; Female; Male; Morphine; Naloxone; Nasal Mucosa; Rats; Rats, Inbred Strains; Salivation; Substance P; Substance Withdrawal Syndrome; Tears | 1986 |
Locomotor activity and contracture of isolated ileum precipitated by naloxone following treatment of guinea-pigs with a single dose of morphine.
Topics: Animals; Atropine; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Motor Activity; Naloxone; Substance P; Substance Withdrawal Syndrome | 1987 |
Excess release of substance P from the spinal cord of mice during morphine withdrawal and involvement of the enhancement of presynaptic Ca2+ entry.
Topics: Animals; Calcium; Male; Mice; Morphine; Spinal Cord; Substance P; Substance Withdrawal Syndrome; Synapses | 1987 |
Substance P and [leucine]enkephalin release in guinea pig ileum during naloxone-precipitated morphine withdrawal.
Topics: Animals; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Morphine Dependence; Myenteric Plexus; Naloxone; Substance P; Substance Withdrawal Syndrome | 1989 |
Primary sensory neurones and naloxone-precipitated morphine withdrawal.
Topics: Animals; Blood Pressure; Capsaicin; Female; Male; Morphine Dependence; Naloxone; Nerve Fibers; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Substance P; Substance Withdrawal Syndrome; Time Factors | 1989 |
Captopril and capsaicin modify opioid withdrawal in the morphine-dependent rat.
Topics: Animals; Capsaicin; Captopril; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance P; Substance Withdrawal Syndrome | 1989 |
[Effect of glycine on chronic morphinism].
Topics: Aggression; Animals; Disease Models, Animal; Drug Synergism; Glycine; Humans; Mice; Morphine Dependence; Nalorphine; Substance P; Substance Withdrawal Syndrome | 1974 |
Pharmacological analysis of central actions of synthetic substance P.
Topics: Aggression; Animals; Blood-Brain Barrier; Desipramine; Humans; Male; Mice; Morphine; Strychnine; Substance P; Substance Withdrawal Syndrome; Time Factors | 1973 |