Page last updated: 2024-08-23

substance p and Schizophrenia

substance p has been researched along with Schizophrenia in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199015 (53.57)18.7374
1990's7 (25.00)18.2507
2000's3 (10.71)29.6817
2010's2 (7.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Hattori, K; Hidese, S; Ishida, I; Kunugi, H; Matsuo, J; Yoshida, F1
Ballard, TM; Hernandez, MC; Hoffmann, T; Knoflach, F; Malherbe, P; Porter, RH; Schnider, P; Spooren, W; Steward, L; Wettstein, JG1
Ishida, T; Kashima, H; Nakajima, S; Suzuki, T; Uchida, H; Watanabe, K1
Caberlotto, L; Carletti, R; Corsi, M; Melotto, S1
Toru, M1
Ichikawa, H; Toru, M1
Adachi, S; Kaiya, H; Moriuchi, I; Namba, M; Tamura, Y; Tanaka, M; Yanaihara, C; Yanaihara, N; Yoshida, H1
Bouras, C; Constantinidis, J; Richard, J1
Shibuya, H1
Bacarese-Hamilton, AJ; Crow, TJ; Ferrier, IN; Johnstone, EC; Lee, Y; McGregor, G; O'Shaughnessey, D; Owens, DG; Polak, JM; Roberts, GW1
Heikkilä, L; Le Grevés, P; Nyberg, F; Rimón, R; Salmela, L; Terenius, L1
Augood, SJ; Emson, PC; Faull, RL; Harrington, KA; McKenna, PJ1
Arinami, T; Hamaguchi, H; Itokawa, M; Li, L; Mitsushio, H; Toru, M1
Benzer, A; Fischer-Colbrie, R; Fleischhacker, WW; Kirchmair, R; Miller, C; Saria, A; Troger, J; Winkler, H1
Aloe, L; Angelucci, F; Fiore, M; Koch, T; Korf, J; Talamini, L1
Chahl, LA; Crawter, VC; Tooney, PA1
Omenn, GS1
Wetterberg, L1
Heikkilä, L; Rimón, R; Terenius, L1
Iadarola, MJ; Kleinman, JE; Ofri, D1
Satoh, K1
Bogerts, B; Zech, M1
Kalivas, PW1
Bracha, HS; Kleinman, JE1
Kaiya, H; Morikiyo, M; Ofuji, M; Takeuchi, K; Uematsu, M1
Wu, YS1
Gillin, CJ; Govoni, S; Hong, J; Iadarola, M; Kleinman, JE1

Reviews

9 review(s) available for substance p and Schizophrenia

ArticleYear
[Brain of patients with chronic schizophrenia and neurotransmitters].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:10

    Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chronic Disease; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Humans; Neurotransmitter Agents; Receptors, Dopamine D2; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Substance P; Tyrosine 3-Monooxygenase

2005
[Neurotransmitters and neuropeptides in schizophrenia].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1984, Volume: 29, Issue:14

    Topics: Acetylcholine; Brain Chemistry; Endorphins; Enkephalins; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Nerve Tissue Proteins; Neurotransmitter Agents; Norepinephrine; Schizophrenia; Serotonin; Substance P; Vasoactive Intestinal Peptide

1984
Putative peptide neurotransmitters in human neuropathology: a review of topography and clinical implications.
    Clinical neuropathology, 1983, Volume: 2, Issue:2

    Topics: Alzheimer Disease; Brain Mapping; Central Nervous System Diseases; Cholecystokinin; Enkephalins; Humans; Huntington Disease; Limbic System; Nerve Tissue Proteins; Neurotransmitter Agents; Parkinson Disease; Schizophrenia; Substance P; Substance-Related Disorders

1983
[Neuropeptides and mental disorders].
    Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:5

    Topics: Aged; Alzheimer Disease; Animals; Brain; Cholecystokinin; Depressive Disorder; Endorphins; Female; Humans; Male; Mental Disorders; Middle Aged; Nerve Tissue Proteins; Neurotransmitter Agents; Schizophrenia; Substance P; Vasopressins

1983
Neurochemistry and behavior in man.
    The Western journal of medicine, 1976, Volume: 125, Issue:6

    Topics: Affective Symptoms; Behavior; Biogenic Amines; Brain Chemistry; Cyclic AMP; Cyclic GMP; Deficiency Diseases; Humans; Neurochemistry; Neurons; Neurotransmitter Agents; Pain; Peptides; Prostaglandins; Proteins; Receptors, Drug; Schizophrenia; Substance P; Substance-Related Disorders; Synaptic Transmission

1976
[Developing lines in psychoendocrinology].
    Lakartidningen, 1977, Feb-16, Volume: 74, Issue:7

    Topics: Adrenocorticotropic Hormone; Animals; Cortisone; Electroconvulsive Therapy; Endocrine System Diseases; Hormones; Humans; Learning; Memory; Mental Disorders; MSH Release-Inhibiting Hormone; Nerve Tissue Proteins; Peptides; Psychoses, Substance-Induced; Psychotropic Drugs; Schizophrenia; Somatomedins; Somatostatin; Steroids; Substance P; Thyrotropin; Vasopressins

1977
Interactions between neuropeptides and dopamine neurons in the ventromedial mesencephalon.
    Neuroscience and biobehavioral reviews, 1985,Winter, Volume: 9, Issue:4

    Topics: Animals; Behavior, Animal; Cats; Cholecystokinin; Dopamine; Enkephalins; Haplorhini; Humans; Limbic System; Mesencephalon; Nerve Tissue Proteins; Neurokinin A; Neurotensin; Rats; Schizophrenia; Substance P; Swine

1985
Postmortem neurochemistry in schizophrenia.
    The Psychiatric clinics of North America, 1986, Volume: 9, Issue:1

    Topics: Acetylcholine; Brain; Brain Chemistry; Cholecystokinin; Dopamine; Endorphins; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Neurotensin; Neurotransmitter Agents; Norepinephrine; Peptides; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Dopamine D2; Schizophrenia; Serotonin; Substance P

1986
Substance P involved in mental disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12 Suppl

    Topics: Animals; Antipsychotic Agents; Brain; Humans; Mental Disorders; Schizophrenia; Substance P

1988

Trials

2 trial(s) available for substance p and Schizophrenia

ArticleYear
Plasma substance P level in patients with schizophrenia: a cross-sectional study.
    Psychiatry and clinical neurosciences, 2011, Volume: 65, Issue:5

    Topics: Aged; Antipsychotic Agents; Biomarkers; Cross-Sectional Studies; Dose-Response Relationship, Drug; Humans; Pneumonia, Aspiration; Schizophrenia; Smoking; Substance P

2011
CSF of neuroleptic-naive first-episode schizophrenic patients: levels of biogenic amines, substance P, and peptides derived from chromogranin A (GE-25) and secretogranin II (secretoneurin).
    Biological psychiatry, 1996, Jun-01, Volume: 39, Issue:11

    Topics: Adult; Biogenic Amines; Chromatography, High Pressure Liquid; Chromogranin A; Chromogranins; Female; Humans; Male; Neuropeptides; Psychiatric Status Rating Scales; Radioimmunoassay; Schizophrenia; Secretogranin II; Substance P

1996

Other Studies

17 other study(ies) available for substance p and Schizophrenia

ArticleYear
Plasma neuropeptide levels in patients with schizophrenia, bipolar disorder, or major depressive disorder and healthy controls: A multiplex immunoassay study.
    Neuropsychopharmacology reports, 2023, Volume: 43, Issue:1

    Topics: alpha-MSH; beta-Endorphin; Bipolar Disorder; Depressive Disorder, Major; Humans; Immunoassay; Neurotensin; Oxytocin; Schizophrenia; Substance P

2023
Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK₁ and NK₃ receptors.
    British journal of pharmacology, 2011, Volume: 162, Issue:4

    Topics: Action Potentials; Amides; Aminopyridines; Animals; Antipsychotic Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Female; Gerbillinae; Guinea Pigs; HEK293 Cells; Humans; In Vitro Techniques; Inositol; Ligands; Macaca fascicularis; Male; Mesencephalon; Mice; Neurokinin-1 Receptor Antagonists; Neurons; Phosphorylation; Pyridines; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Schizophrenia; Substance P; Substantia Nigra

2011
Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia.
    The European journal of neuroscience, 2005, Volume: 21, Issue:6

    Topics: Adult; Aged; Amygdala; Binding Sites; Down-Regulation; Female; Humans; Male; Middle Aged; Mood Disorders; Protein Precursors; RNA, Messenger; Schizophrenia; Substance P; Tachykinins; Tritium

2005
Substance P-like immunoreactivity in plasma of psychotic patients and effects of neuroleptics and electroconvulsive therapy.
    Psychiatry research, 1981, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Chlorpromazine; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Neurocognitive Disorders; Neurotic Disorders; Psychotic Disorders; Schizophrenia; Substance P

1981
Peptides, the limbic lobe and schizophrenia.
    Brain research, 1983, Dec-12, Volume: 288, Issue:1-2

    Topics: Brain; Brain Chemistry; Cholecystokinin; Hormones; Humans; Limbic System; Neurotensin; Schizophrenia; Somatostatin; Substance P; Tissue Distribution; Vasoactive Intestinal Peptide

1983
Elevation of substance P-like peptides in the CSF of psychiatric patients.
    Biological psychiatry, 1984, Volume: 19, Issue:4

    Topics: Adult; Depressive Disorder; Female; Humans; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Peptide Fragments; Peptides; Radioimmunoassay; Schizophrenia; Substance P

1984
Dopamine D1 receptor, D2 receptor, proenkephalin A and substance P gene expression in the caudate nucleus of control and schizophrenic tissue: a quantitative cellular in situ hybridisation study.
    Brain research. Molecular brain research, 1995, Volume: 33, Issue:2

    Topics: Aged; Autoradiography; Caudate Nucleus; Enkephalins; Female; Gene Expression; Humans; In Situ Hybridization; Male; Middle Aged; Oligonucleotide Probes; Organ Specificity; Phosphorus Radioisotopes; Protein Precursors; Putamen; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; Schizophrenia; Substance P

1995
An insertion/deletion polymorphism in the angiotensin converting enzyme gene is associated with both brain substance P contents and affective disorders.
    Biological psychiatry, 1996, Dec-01, Volume: 40, Issue:11

    Topics: Adult; Aged; Alleles; Brain Chemistry; DNA Transposable Elements; Female; Genotype; Humans; Male; Middle Aged; Mood Disorders; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Schizophrenia; Sequence Deletion; Substance P

1996
Prenatal methylazoxymethanol acetate alters behavior and brain NGF levels in young rats: a possible correlation with the development of schizophrenia-like deficits.
    Neuropharmacology, 1999, Volume: 38, Issue:6

    Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Brain; Disease Models, Animal; Exploratory Behavior; Female; Methylazoxymethanol Acetate; Nerve Growth Factors; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Schizophrenia; Social Behavior; Substance P

1999
Increased tachykinin NK(1) receptor immunoreactivity in the prefrontal cortex in schizophrenia.
    Biological psychiatry, 2001, Mar-15, Volume: 49, Issue:6

    Topics: Adult; Aged; Female; Humans; Immunohistochemistry; Killer Cells, Natural; Male; Middle Aged; Prefrontal Cortex; Schizophrenia; Substance P; Tachykinins

2001
Dynorphin A and substance P in the cerebrospinal fluid of schizophrenic patients.
    Psychiatry research, 1990, Volume: 34, Issue:3

    Topics: Adult; Clopenthixol; Dose-Response Relationship, Drug; Drug Administration Schedule; Dynorphins; Female; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Substance P

1990
Enkephalin, dynorphin and substance P in postmortem substantia nigra from normals and schizophrenic patients.
    Life sciences, 1991, Volume: 48, Issue:20

    Topics: Adult; Chromatography, High Pressure Liquid; Dynorphins; Enkephalin, Methionine; Female; Humans; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Schizophrenia; Substance P; Substantia Nigra

1991
Mesocortical neurotensin/dopamine system: is it involved in the pathogenesis of schizophrenia?
    The Japanese journal of psychiatry and neurology, 1991, Volume: 45, Issue:2

    Topics: Animals; Brain Mapping; Cerebral Cortex; Dopamine; Enkephalin, Leucine; Frontal Lobe; Growth Hormone; Humans; Macaca; Male; Neurotensin; Schizophrenia; Schizophrenic Psychology; Substance P; Synaptic Transmission; Tyrosine 3-Monooxygenase

1991
Methionine-enkephalin and substance P in the basal ganglia of normals, Parkinson patients, Huntington patients, and schizophrenics. A qualitative immunohistochemical study.
    Acta neuropathologica, 1985, Volume: 68, Issue:1

    Topics: Adult; Aged; Basal Ganglia; Enkephalin, Methionine; Female; Humans; Huntington Disease; Immunoenzyme Techniques; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Postencephalitic; Schizophrenia; Substance P

1985
[The neurochemistry of schizophrenia].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1989, Volume: 91, Issue:8

    Topics: Adult; Aged; Brain; Choline O-Acetyltransferase; Enkephalin, Methionine; Female; Glutamates; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia; Substance P; Tyrosine 3-Monooxygenase

1989
[Observations on substance P in the brain and spinal cord in schizophrenia].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1989, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Brain Chemistry; Humans; Immunohistochemistry; Middle Aged; Schizophrenia; Spinal Cord; Substance P

1989
Neuropeptides in human brain--postmortem studies.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:1

    Topics: Adult; Aged; Alcoholism; Brain Chemistry; Cholecystokinin; Enkephalin, Methionine; Heroin Dependence; Humans; Mental Disorders; Middle Aged; Nerve Tissue Proteins; Neurotensin; Psychotic Disorders; Schizophrenia; Substance P; Suicide

1985