substance p has been researched along with Polyarthritis in 66 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (21.21) | 18.7374 |
1990's | 34 (51.52) | 18.2507 |
2000's | 13 (19.70) | 29.6817 |
2010's | 5 (7.58) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Cai, GQ; Chen, XD; He, JY; Li, D; Li, Z; Shen, C; Wang, H; Zhang, X; Zheng, XF; Zhu, JF | 1 |
Gao, T; Hökfelt, T; Shi, T; Su, J; Svensson, CI; Wiesenfeld-Hallin, Z; Xiang, Q; Xu, X | 1 |
Matsuo, S; Murakami, K; Nakagawa, H; Nishimura, K | 1 |
Borbély, É; Helyes, Z; Kemény, Á; Markovics, A; McDougall, JJ; Pintér, E; Quinn, JP; Sándor, K; Szolcsányi, J | 1 |
Almarestani, L; Bennett, GJ; Krause, JE; Ribeiro-da-Silva, A; Waters, SM | 1 |
Câmara, PR; Casatti, CA; Cenac, N; Costa, SK; Denadai-Souza, A; Muscará, MN; Vergnolle, N; Yshii, LM | 1 |
Gentle, MJ; Lunam, CA | 1 |
Brain, SD; Keeble, JE | 1 |
Blake, DR; Haigh, R; Mapp, PI; McCabe, CS; Shenker, NG | 1 |
Cahill, CM; Henry, JL; Ménard, HA; Ribeiro-da-Silva, A; Sharif Naeini, R | 1 |
Castro, AR; Lima, D; Pinto, M; Tavares, I | 1 |
Forsgren, S; Grimsholm, O; Guo, Y; Ny, T; Rantapää-Dahlqvist, S | 1 |
Colpaert, FC; Donnerer, J; Lembeck, F | 1 |
Bervoets, K; Colpaert, FC | 1 |
Basbaum, AI; Clark, R; Devor, M; Helms, C; Levine, JD; Moskowitz, MA | 1 |
Locatelli, L; Mantegazza, P; Panerai, AE; Sacerdote, P | 1 |
Blake, DR; Chen, ST; Cruwys, SC; Garrett, N; Kidd, BL; Mapp, PI; Polak, JM; Terenghi, G; Walsh, DA | 1 |
Buma, P | 1 |
Locatelli, L; Panerai, AE; Sacerdote, P | 1 |
Bileviciute, I; Ekblom, A; Lundeberg, T; Theodorsson, E | 1 |
Alstergren, P; Appelgren, A; Appelgren, B; Kopp, S; Lundeberg, T; Theodorsson, E | 1 |
Aloe, L; Kollias, G; Micera, A; Probert, L; Tirassa, P | 1 |
Cruwys, SC; Garrett, NE; Kidd, BL; Tomlinson, DR | 1 |
Ferrell, WR; Lam, FY | 2 |
Fitzgerald, O; Veale, DJ | 1 |
Carraway, RE; Joyce, TJ; Yood, RA | 1 |
Betts, WH; Halliday, DA; McNeil, JD; Scicchitano, R | 1 |
Blake, DR; Cruwys, SC; Garrett, NE; Jolliffe, VA; Kidd, BL; Mapp, PI | 1 |
Gur Aryeh, I; Niv, D | 1 |
Neugebauer, V; Rumenapp, P; Schaible, HG | 1 |
Alstergren, P; Appelgren, A; Appelgren, B; Carleson, J; Kopp, S; Lundeberg, T; Theodorsson, E | 1 |
Appelgren, A; Appelgren, B; Kopp, S; Lundeberg, T; Theodorsson, E | 2 |
Heppelmann, B; Pawlak, M | 2 |
Hanesch, U; Heppelmann, B; Schmidt, RF | 1 |
Appelgren, A; Appelgren, B; Bileviciute, I; Carleson, J; Kogner, P; Kopp, S; Lundeberg, T; Theodorsson, E; Yousef, N | 1 |
Cerinic, MM; Cutolo, M; Generini, S; Konttinen, Y | 1 |
Beck, U; Geisslinger, G; Neugebauer, V; Schaible, HG | 1 |
Ferreira, SH; Tonussi, CR | 1 |
Binder, W; Carmody, J; Walker, J | 1 |
Buma, P; Elmans, L; Schrama, LH; Van Den Berg, WB | 1 |
Ebersberger, A; Malcangio, M; Mazario, J; Meyer-Tuve, A; Schaible, HG | 1 |
Hanesch, U; Heppelmann, B; Pawlak, M; Schmidt, RF | 1 |
Kopp, S | 1 |
Han, HC; Han, JS; Hong, SK; Hwang, JM; Kim, YI; Min, SS; Na, HS; Yoon, YW | 1 |
Ferrell, WR; Lam, FY; Scott, DT | 1 |
Chrousos, GP; Crofford, LJ; Goldmuntz, EA; Karalis, K; Sano, H; Webster, EL; Wilder, RL | 1 |
Halliday, DA; McNeil, JD; Scicchitano, R | 1 |
Blake, DR; Cruwys, SC; Garrett, NE; Kidd, BL; Mapp, PI | 1 |
Chiu, B; Inman, RD; Marshall, KW | 1 |
Bloch, JG; Bronner, C; Bueb, JL; Landry, Y; Mousli, M | 1 |
Kimball, ES | 1 |
Blancuzzi, VJ; Jeng, AY; O'Byrne, EM; Peppard, J; Simke, JP; Wilson, DE; Wong, M | 1 |
Cagnoni, M; Del Bianco, E; Geppetti, P; Marabini, S; Marchesoni, A; Matucci-Cerinic, M; Partsch, G; Tosi, S | 1 |
Basbaum, AI; Levine, JD; Moskowitz, MA | 1 |
Bernard, C; Chayvialle, JA; Chery-Croze, S; Kocher, L | 1 |
Pert, CB; Ruff, MR; Wahl, SM | 1 |
Oku, R; Satoh, M; Takagi, H | 1 |
Bianchi, M; Brini, A; Mantegazza, P; Panerai, AE; Sacerdote, P | 1 |
Kimball, ES; Persico, FJ; Vaught, JL | 1 |
Gramsch, C; Herz, A; Millan, MJ; Müller, S; Nohr, D; Stein, C; Weihe, E | 1 |
Cao, WH; Deng, Y; Dong, XT; Lu, ZS; Zhang, TJ | 1 |
Fontanet, A; Menkès, CJ | 1 |
de Castro Costa, M; Gybels, J; Schoenen, J; Van Hees, J; Vanderhaeghen, JJ | 1 |
7 review(s) available for substance p and Polyarthritis
Article | Year |
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A role for substance P in arthritis?
Topics: Animals; Arthralgia; Arthritis; Humans; Joints; Neurokinin-1 Receptor Antagonists; Posterior Horn Cells; Receptors, Neurokinin-1; Sensory Receptor Cells; Substance P; Synovial Membrane | 2004 |
Symmetry, T cells and neurogenic arthritis.
Topics: Arthritis; Arthropathy, Neurogenic; Calcitonin Gene-Related Peptide; Humans; Nerve Net; Peripheral Nervous System Diseases; Substance P; T-Lymphocytes | 2004 |
[Capsaicin for arthritic pain].
Topics: Analgesics; Animals; Arthritis; Arthritis, Experimental; Capsaicin; Humans; Pain; Substance P | 1996 |
Neuropeptides and steroid hormones in arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Female; Gonadal Steroid Hormones; Humans; Hypothalamo-Hypophyseal System; Male; Neuropeptides; Pain; Peripheral Nerves; Pituitary-Adrenal System; Pregnancy; Steroids; Substance P | 1998 |
Neuroendocrine, immune, and local responses related to temporomandibular disorders.
Topics: Arthritis; Calcitonin Gene-Related Peptide; Dinoprostone; Facial Pain; Fibromyalgia; Humans; Hyperalgesia; Inflammation Mediators; Interleukin-1; Leukotriene B4; Masseter Muscle; Neuroimmunomodulation; Neuropeptide Y; Neuropeptides; Neurosecretory Systems; Open Bite; Serotonin; Substance P; Synovial Fluid; Temporomandibular Joint Disorders; Tumor Necrosis Factor-alpha | 2001 |
Role of substance P in inflammatory arthritis.
Topics: Animals; Arthritis; Humans; Joints; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Synovial Fluid | 1992 |
Substance P, cytokines, and arthritis.
Topics: Animals; Arthritis; Biological Factors; Bradykinin; Cytokines; Histamine; Humans; Interleukin-1; Interleukin-6; Substance P; Tumor Necrosis Factor-alpha | 1990 |
59 other study(ies) available for substance p and Polyarthritis
Article | Year |
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Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip.
Topics: Adult; Arthritis; Calcitonin Gene-Related Peptide; Disease Progression; Female; Gene Expression Regulation; Hip Dislocation, Congenital; Humans; Male; Middle Aged; Substance P; Synovial Fluid; Synovial Membrane; Young Adult | 2015 |
Phenotypic changes in dorsal root ganglion and spinal cord in the collagen antibody-induced arthritis mouse model.
Topics: Activating Transcription Factor 3; Animals; Antibodies; Arthritis; Calcium Channels; Collagen; Disease Models, Animal; Galanin; Ganglia, Spinal; Hyperalgesia; Lectins; Lipopolysaccharides; Male; Mice; Mice, Inbred CBA; Nerve Tissue Proteins; Neuropeptide Y; Spinal Cord; Substance P; Time Factors | 2015 |
Changes in peptidergic fiber density in the synovium of mice with collagenase-induced acute arthritis.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Collagenases; Knee Joint; Male; Mice; Mice, Inbred C57BL; Nerve Fibers; Osteoarthritis; Substance P; Synovial Membrane | 2015 |
Role of capsaicin-sensitive nerves and tachykinins in mast cell tryptase-induced inflammation of murine knees.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Edema; Hyperalgesia; Knee Joint; Male; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Pain; Protein Precursors; Receptor, PAR-2; Receptors, Neurokinin-1; Substance P; Tachykinins; Touch; TRPV Cation Channels; Tryptases | 2016 |
De novo expression of the neurokinin 1 receptor in spinal lamina I pyramidal neurons in polyarthritis.
Topics: Adjuvants, Immunologic; Analysis of Variance; Animals; Arthritis; Cholera Toxin; Freund's Adjuvant; Gene Expression; Immunohistochemistry; Male; Neurons; Photomicrography; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P | 2009 |
PAR(2) and temporomandibular joint inflammation in the rat.
Topics: Animals; Arthritis; Arthropathy, Neurogenic; Immunity, Innate; Injections, Intra-Articular; Male; Nerve Fibers; Neuroimmunomodulation; Neurokinin-1 Receptor Antagonists; Neurons; Neutrophil Infiltration; Neutrophils; Oligopeptides; Pain Measurement; Piperidines; Plasma; Quinuclidines; Rats; Rats, Wistar; Receptor, PAR-2; Sensory Receptor Cells; Substance P; Temporomandibular Joint; Temporomandibular Joint Disorders; Trigeminal Ganglion; Trypsin; Ubiquitin Thiolesterase | 2010 |
Substance P immunoreactive nerve fibres in the domestic chick ankle joint before and after acute urate arthritis.
Topics: Animals; Arthralgia; Arthritis; Chickens; Disease Models, Animal; Down-Regulation; Female; Gout; Immunohistochemistry; Male; Nerve Fibers; Nociceptors; Sensory Receptor Cells; Substance P; Synovial Membrane; Tarsal Joints; Uric Acid | 2004 |
Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ankle; Arthritis; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Agonists; Freund's Adjuvant; Functional Laterality; Immunohistochemistry; Iontophoresis; Male; Microscopy, Immunoelectron; N-Methylaspartate; Neuronal Plasticity; Neurons; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Spinal Cord; Substance P; Time Factors | 2005 |
Secondary hyperalgesia in the monoarthritic rat is mediated by GABAB and NK1 receptors of spinal dorsal horn neurons: a behavior and c-fos study.
Topics: Animals; Arthritis; Baclofen; Behavior, Animal; Drug Interactions; Freund's Adjuvant; GABA Agonists; Gene Expression; Hyperalgesia; Immunohistochemistry; Male; Pain Measurement; Pain Threshold; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Substance P | 2006 |
Are neuropeptides important in arthritis? Studies on the importance of bombesin/GRP and substance P in a murine arthritis model.
Topics: Animals; Arthritis; Bombesin; Disease Models, Animal; Gastrin-Releasing Peptide; Male; Mice; Neuropeptides; Substance P | 2007 |
Effects of capsaicin on inflammation and on the substance P content of nervous tissues in rats with adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Capsaicin; Fatty Acids, Unsaturated; Inflammation; Kinetics; Male; Mycobacterium; Nervous System; Rats; Rats, Inbred Strains; Substance P | 1983 |
Respiratory effects of intrathecal capsaicin in arthritic and non-arthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Body Weight; Capsaicin; Injections, Spinal; Male; Pain; Rats; Rats, Inbred Strains; Respiration; Substance P | 1984 |
Intraneuronal substance P contributes to the severity of experimental arthritis.
Topics: Animals; Arthritis; Double-Blind Method; Hindlimb; Joints; Neurons, Afferent; Rats; Substance P | 1984 |
Effect of ibuprofen and diclofenac on the chemotaxis induced by substance P and transforming growth factor-beta on human monocytes and polymorphonuclear cells.
Topics: Arthritis; Chemotaxis; Diclofenac; Humans; Ibuprofen; In Vitro Techniques; Monocytes; Neutrophils; Substance P; Synovial Fluid; Transforming Growth Factor beta | 1993 |
Monoarthritis in the rat knee induces bilateral and time-dependent changes in substance P and calcitonin gene-related peptide immunoreactivity in the spinal cord.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Ganglia, Spinal; Immunohistochemistry; Knee Joint; Male; Neurons; Rats; Rats, Wistar; Spinal Cord; Substance P; Time Factors; Tissue Distribution | 1993 |
Innervation of the patella. An immunohistochemical study in mice.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Edetic Acid; GAP-43 Protein; Immunohistochemistry; Knee Joint; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurofilament Proteins; Substance P | 1994 |
Inhibitory effect of NSAIDs on the chemotaxis induced by substance P on human monocytes and polymorphonuclear cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Chemotaxis, Leukocyte; Diclofenac; Humans; Ibuprofen; Indomethacin; Leukocytes; Monocytes; Neutrophils; Piroxicam; Substance P | 1993 |
Substance P-, neurokinin A-, calcitonin gene-related peptide- and neuropeptide Y-like immunoreactivity (-LI) in rat knee joint synovial fluid during acute monoarthritis is not correlated with concentrations of neuropeptide-LI in cerebrospinal fluid and pl
Topics: Acute Disease; Animals; Arthritis; Calcitonin Gene-Related Peptide; Knee Joint; Male; Neurokinin A; Neuropeptide Y; Neuropeptides; Osmolar Concentration; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Substance P; Synovial Fluid | 1994 |
Co-variation of neuropeptide Y, calcitonin gene-related peptide, substance P and neurokinin A in joint fluid from patients with temporomandibular joint arthritis.
Topics: Adult; Aged; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Male; Middle Aged; Neurokinin A; Neuropeptide Y; Osteoarthritis; Regression Analysis; Spondylitis, Ankylosing; Substance P; Synovial Fluid; Temporomandibular Joint Disorders | 1995 |
Effect of NGF antibodies on mast cell distribution, histamine and substance P levels in the knee joint of TNF-arthritic transgenic mice.
Topics: Animals; Antibodies; Arthritis; Histamine; Knee Joint; Mast Cells; Mice; Mice, Transgenic; Nerve Growth Factors; Substance P | 1995 |
Streptozotocin-induced diabetes decreases substance P levels in experimental arthritis in the rat knee.
Topics: Animals; Arthritis; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Ganglia, Spinal; Immunohistochemistry; Knee Joint; Rats; Substance P; Time Factors | 1995 |
Acute inflammation in the rat knee joint attenuates sympathetic vasoconstriction but enhances neuropeptide-mediated vasodilatation assessed by laser Doppler perfusion imaging.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Carrageenan; Electric Stimulation; Knee Joint; Lasers; Male; Neuropeptides; Rats; Rats, Wistar; Substance P; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 1993 |
Sympathetic nervous system in chronic joint pain.
Topics: Arthritis; Humans; Substance P; Sympathetic Nervous System; Synovial Membrane | 1993 |
Quantitation of substance-P and its metabolites in plasma and synovial fluid from patients with arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis; Chromatography, High Pressure Liquid; Drug Stability; Endopeptidases; False Positive Reactions; Female; Humans; Indicators and Reagents; Male; Middle Aged; Peptide Fragments; Protease Inhibitors; Radioimmunoassay; Reference Values; Substance P; Synovial Fluid | 1993 |
A role for the C-terminal fragment of substance P,SP7-11 in the pathogenesis of arthritis.
Topics: Amino Acid Sequence; Animals; Arthritis; Cartilage, Articular; Cattle; Collagenases; Dinoprostone; Kinetics; Molecular Sequence Data; Neurokinin A; Neurokinin B; Peptide Fragments; Substance P | 1993 |
Neurogenic influences on contralateral responses during experimental rat monoarthritis.
Topics: Analysis of Variance; Animals; Arthritis; Arthropathy, Neurogenic; Capsaicin; Cell Count; Ganglia, Spinal; Male; Microspheres; Rats; Rats, Wistar; Substance P; Vasomotor System | 1995 |
The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arthritis; Benzamides; Carrageenan; Hyperalgesia; Iontophoresis; Kaolin; Knee Joint; Male; Neurokinin A; Nociceptors; Pain; Piperidines; Pressure; Rats; Rats, Wistar; Receptors, Neurokinin-2; Spinal Cord; Substance P | 1996 |
A model for the study of experimentally induced temporomandibular arthritis in rats: the effect of human recombinant interleukin-1 alpha on neuropeptide-like immunoreactivity.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Humans; Interleukin-1; Male; Neuroimmunomodulation; Neurokinin A; Neuropeptide Y; Neuropeptides; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Substance P; Synovial Fluid; Temporomandibular Joint; Temporomandibular Joint Disorders | 1996 |
Neuropeptides in the arthritic TMJ and symptoms and signs from the stomatognathic system with special consideration to rheumatoid arthritis.
Topics: Adult; Arthritis; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Inflammation Mediators; Male; Middle Aged; Neuroimmunomodulation; Neurokinin A; Neuropeptide Y; Neuropeptides; Pain; Pain Measurement; Range of Motion, Articular; Statistics, Nonparametric; Substance P; Synovial Fluid; Temporomandibular Joint Disorders | 1995 |
Sensitisation of articular afferents in normal and inflamed knee joints by substance P in the rat.
Topics: Animals; Arthritis; Knee Joint; Male; Neurons, Afferent; Pain; Rats; Rats, Wistar; Reference Values; Rotation; Substance P | 1997 |
Quantification of cat's articular afferents containing calcitonin gene-related peptide or substance P innervating normal and acutely inflamed knee joints.
Topics: Acute Disease; Afferent Pathways; Animals; Arthritis; Calcitonin Gene-Related Peptide; Case-Control Studies; Cats; Female; Knee Joint; Male; Reference Values; Substance P | 1997 |
Effects of capsaicin in temporomandibular joint arthritis in rats.
Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Capsaicin; Chromatography, High Pressure Liquid; Denervation; Disease Models, Animal; Female; Mandibular Nerve; Neurons, Afferent; Neuropeptide Y; Neurotoxins; Nontuberculous Mycobacteria; Radioimmunoassay; Rats; Rats, Inbred Lew; Substance P; Sympathetic Nervous System; Temporomandibular Joint; Temporomandibular Joint Disorders; Trigeminal Ganglion | 1997 |
Inhibitory effect of somatostatin on the mechanosensitivity of articular afferents in normal and inflamed knee joints of the rat.
Topics: Afferent Pathways; Animals; Arthritis; Bradykinin; Knee Joint; Male; Rats; Rats, Wistar; Reference Values; Somatostatin; Stress, Mechanical; Substance P | 1997 |
Substance P-associated increase of intra-articular temperature and pain threshold in the arthritic TMJ.
Topics: Adult; Arthritis; Body Temperature; Facial Pain; Female; Glucocorticoids; Humans; Immunohistochemistry; Microcirculation; Neuroimmunomodulation; Pain Measurement; Pain Threshold; Paracentesis; Statistics, Nonparametric; Substance P; Synovial Fluid; Temporomandibular Joint; Temporomandibular Joint Disorders | 1998 |
The effects of S- and R-flurbiprofen on the inflammation-evoked intraspinal release of immunoreactive substance P--a study with antibody microprobes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Flurbiprofen; Immunologic Techniques; Knee Joint; Male; Rats; Rats, Wistar; Spinal Cord; Stereoisomerism; Substance P | 1998 |
Tumour necrosis factor-alpha mediates carrageenin-induced knee-joint incapacitation and also triggers overt nociception in previously inflamed rat knee-joints.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bradykinin; Bradykinin Receptor Antagonists; Carrageenan; Dinoprostone; Inflammation Mediators; Injections, Intra-Articular; Knee Joint; Male; Pain; Rats; Rats, Wistar; Stimulation, Chemical; Substance P; Tumor Necrosis Factor-alpha | 1999 |
Effect of gender on anti-inflammatory and analgesic actions of two kappa-opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetamides; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Arthritis; Arthritis, Experimental; Female; Hot Temperature; Male; Narcotics; Pain Measurement; Physical Stimulation; Pyrrolidines; Rats; Sex Characteristics; Substance P; Time Factors | 2000 |
Neurovascular plasticity in the knee joint of an arthritic mouse model.
Topics: Animals; Arthritis; Blood Vessels; Calcitonin Gene-Related Peptide; Knee Joint; Male; Mice; Mice, Inbred C57BL; Nerve Fibers; Nerve Tissue; Neuronal Plasticity; Reference Values; Serum Albumin, Bovine; Substance P; Synovial Membrane; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 2000 |
Effect of brain-derived neurotrophic factor on the release of substance P from rat spinal cord.
Topics: Animals; Arthritis; Brain-Derived Neurotrophic Factor; Electric Stimulation; Hyperalgesia; Knee Joint; Male; Posterior Horn Cells; Rats; Rats, Wistar; Spinal Cord; Substance P; Touch | 2001 |
The neurokinin-1 receptor antagonist RP 67580 reduces the sensitization of primary afferents by substance P in the rat.
Topics: Acute Disease; Animals; Arthritis; Dose-Response Relationship, Drug; Indoles; Isoindoles; Knee Joint; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Rats; Rats, Wistar; Substance P | 2001 |
Local neurokinin-1 receptor in the knee joint contributes to the induction, but not maintenance, of arthritic pain in the rat.
Topics: Animals; Arthritis; Carrageenan; Dose-Response Relationship, Drug; Knee Joint; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nociceptors; Pain; Peripheral Nerves; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Weight-Bearing | 2002 |
Acute inflammation enhances substance P-induced plasma protein extravasation in the rat knee joint.
Topics: Animals; Arthritis; Blood Proteins; Carrageenan; Injections, Intra-Articular; Knee Joint; Male; Rats; Rats, Inbred Strains; Substance P; Synovial Fluid | 1992 |
Local secretion of corticotropin-releasing hormone in the joints of Lewis rats with inflammatory arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Corticotropin-Releasing Hormone; Dexamethasone; Gene Expression; Inflammation; Joints; Male; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Nude; RNA, Messenger; Substance P; Synovial Membrane | 1992 |
Failure of tachykinins including substance P and its fragments to influence proteoglycan and protein synthesis in bovine chondrocytes in vitro.
Topics: Amino Acid Sequence; Animals; Arthritis; Cartilage, Articular; Cattle; Cells, Cultured; Chromatography, Gel; Interleukin-1; Molecular Sequence Data; Peptide Fragments; Protein Biosynthesis; Proteoglycans; Substance P; Tachykinins | 1992 |
Substance P and arthritis: analysis of plasma and synovial fluid levels.
Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Humans; Joints; Osteoarthritis; Substance P; Synovial Fluid; Wounds and Injuries | 1990 |
[Neuropeptides and inflammation: presumed mechanisms in neurogenic inflammation].
Topics: Arthritis; Humans; Inflammation; Mast Cells; Membrane Proteins; Neuropeptides; Substance P | 1990 |
Increased intra-articular substance P and prostaglandin E2 following injection of interleukin-1 in rabbits.
Topics: Animals; Arthritis; Dinoprostone; Interleukin-1; Joints; Rabbits; Substance P; Therapeutic Irrigation | 1990 |
Substance P and somatostatin levels in rheumatoid arthritis, osteoarthritis, and psoriatic arthritis synovial fluid.
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Osteoarthritis; Psoriasis; Somatostatin; Substance P; Synovial Fluid | 1991 |
The contribution of neurogenic inflammation in experimental arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Arthritis, Rheumatoid; Brain Stem; Humans; Inflammation; Nociceptors; Pain; Rats; Spinal Cord; Substance P; Sympathetic Nervous System | 1985 |
Substance P-, somatostatin-, vasoactive intestinal peptide- and cholecystokinin-like levels in the spinal cord of polyarthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Cholecystokinin; Peptides; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord; Substance P; Vasoactive Intestinal Peptide | 1985 |
Substance P receptor-mediated chemotaxis of human monocytes.
Topics: Arthritis; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Monocytes; Oligopeptides; Peptide Fragments; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P | 1985 |
Release of substance P from the spinal dorsal horn is enhanced in polyarthritic rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Decerebrate State; Male; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Synaptic Transmission | 1987 |
Brain and spinal cord neuropeptides in adjuvant induced arthritis in rats.
Topics: Animals; Arthritis; Arthritis, Experimental; beta-Endorphin; Brain; Dynorphins; Endorphins; Enkephalin, Methionine; Male; Neuropeptides; Rats; Rats, Inbred Strains; Spinal Cord; Substance P; Time Factors; Tissue Distribution | 1987 |
Substance P, neurokinin A, and neurokinin B induce generation of IL-1-like activity in P388D1 cells. Possible relevance to arthritic disease.
Topics: Amino Acid Sequence; Animals; Arthritis; Cell Line; Cell-Free System; Interleukin-1; Leukemia P388; Leukemia, Experimental; Macrophages; Mice; Molecular Sequence Data; Neurokinin A; Peptide Fragments; Substance P | 1988 |
Peptide neuroanatomy of adjuvant-induced arthritic inflammation in rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Enkephalins; Ganglia, Spinal; Immunohistochemistry; Nerve Fibers; Neuropeptides; Protein Precursors; Rats; Rats, Inbred Strains; Skin; Spinal Cord; Substance P | 1988 |
Relation between the therapeutic effect of moxibustion in treating arthralgia and SP and enkephalin in nervous tissues.
Topics: Animals; Arthritis; Arthritis, Experimental; Enkephalin, Leucine; Male; Moxibustion; Pain; Rats; Rats, Inbred Strains; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Substance P | 1989 |
[Hemiplegia and contralateral multiple joint disease caused by chondrocalcinosis].
Topics: Aged; Aged, 80 and over; Arthritis; Chondrocalcinosis; Female; Hemiplegia; Humans; Substance P | 1989 |
Capsaicin suppresses substance P-induced joint inflammation in the rat.
Topics: Animals; Arthritis; Capsaicin; Denervation; Injections, Intra-Articular; Knee Joint; Male; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Substance P; Synovial Membrane | 1989 |
Histochemical changes of substance P, FRAP, serotonin and succinic dehydrogenase in the spinal cord of rats with adjuvant arthritis.
Topics: Acid Phosphatase; Animals; Arthritis; Arthritis, Experimental; Behavior, Animal; Fluorides; Histocytochemistry; Isoenzymes; Male; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Substance P; Succinate Dehydrogenase; Time Factors | 1985 |