Page last updated: 2024-08-23

substance p and Parkinson Disease

substance p has been researched along with Parkinson Disease in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199020 (33.90)18.7374
1990's18 (30.51)18.2507
2000's10 (16.95)29.6817
2010's7 (11.86)24.3611
2020's4 (6.78)2.80

Authors

AuthorsStudies
Greco, A; Lattanzi, R; Maftei, D; Mercuri, NB; Ralli, M; Schirinzi, T; Severini, C1
Greco, A; Mercuri, NB; Polimeni, A; Possenti, R; Ralli, M; Raspa, M; Schirinzi, T; Severini, C; Tirassa, P1
Bissacco, J; Bovenzi, R; Cerroni, R; Di Girolamo, S; Grillo, P; Lattanzi, R; Maftei, D; Magliulo, G; Mascioli, D; Maurizi, R; Mercuri, NB; Passali, FM; Ralli, M; Schirinzi, T; Severini, C; Simonetta, C; Stefani, A; Tirassa, P; Vincenzi, M; Zenuni, H1
Chen, H; Chen, L; Chen, XY; Xue, Y1
Ahn, S; Hong, S; Jang, J; Jeon, S; Jung, YR; Kim, J; Oh, JY; Park, HJ; Park, SU; Shin, HS; Song, MA; Song, TJ1
Doppler, K; Ebentheuer, J; Ebert, S; Sommer, C; Trenkwalder, C; Uçeyler, N; Volkmann, J1
Collier, TJ; Gebremedhin, KG; O'Malley, J; Paumier, KL; Rademacher, DJ; Sisson, KA; Sortwell, CE; Stancati, JA; Steece-Collier, K1
Jin, RR; Lin, Q; Lu, CT; Lv, CZ; Mao, KL; Tian, FR; Wáng, YX; Xiang, Q; Yang, W; Yu, WZ; Zhao, YZ1
Argandoña-Palacios, L; de la Rosa-Prieto, C; Garcia-Muñozguren, S; Martinez-Marcos, A; Saiz-Sanchez, D; Ubeda-Bañon, I1
Bagetta, V; Calabresi, P; Fusco, FR; Ghiglieri, V; Giampà, C; Marinucci, S; Pendolino, V; Picconi, B; Sgobio, C1
Dodiya, HB; Jakate, S; Keshavarzian, A; Kordower, JH; Shannon, KM1
Arai, H; Ebihara, S; Kanda, A; Nakajoh, M; Saito, H; Sasaki, H; Takahashi, H1
Damier, P; Drapier, S1
Alba, F; Banegas, I; Barrero, F; Durán, R; Luna, JD; Morales, B; Prieto, I; Ramírez, M; Vives, F1
Andren, PE; Chergui, K; Svenningsson, P; Zhang, X1
Bouras, C; Constantinidis, J; Richard, J1
Agid, Y; Cesselin, F; Javoy-Agid, F; Legrand, JC; Mauborgne, A1
Carenzi, A; Di Giulio, A; Longo, A; Panerai, AE; Passerini, D; Pezzoli, G1
Rinne, UK; Tenovuo, O; Viljanen, MK1
Beal, MF; Landis, DM; Marshall, PE; Martin, JB; Sagar, SM1
de Ceballos, ML; Fernandez, A; Jenner, P; Marsden, CD2
Caffarra, P; Chiodera, P; Coiro, V; Maestri, D; Saginario, A; Scaglioni, A; Vescovi, PP; Volpi, R; Vourna, S1
Joyce, JN; Rioux, L1
Goto, S; Hirano, A; Ito, H; Sakamoto, S2
Agid, Y; Faucheux, B; Herrero, MT; Hirsch, EC; Levy, R; Vila, M1
Dixon, AK; Freeman, TC; Gubitz, AK; Richardson, PJ1
De Ceballos, ML; López-Lozano, JJ1
Itoh, M; Iwaki, T; Kato, H; Matsuishi, T; Nagamitsu, S; Sakai, T; Shida, N; Shoji, H; Takashima, S; Yamashita, Y1
Aubert, I; Bloch, B; Ghorayeb, I; Normand, E1
Damier, P; Féger, J; Hirsch, EC; Tremblay, L1
Arai, H; Iwasaki, K; Sasaki, H; Satoh, K; Seki, H; Takeda, A; Wang, Q1
Dziewczapolski, G; Gershanik, O; Grandy, DK; Hirsch, E; Kelly, MA; Low, MJ; Murer, MG; Raisman-Vozari, R; Ruberg, M; Rubinstein, M; Salin, P; Tseng, KY; Vila, M1
Andren, PE; Gunne, L; Svenningsson, P1
Forni, C; Kerkerian-Le Goff, L; Manrique, C; Salin, P1
Yoshida, M1
Rinne, UK1
Gibb, WR1
Blessing, WW; Blumbergs, PC; Cotton, RG; Geffen, LB; Halliday, GM1
Goto, S; Hirano, A; Matsumoto, S1
Kolhinen, O; Laihinen, A; Rinne, UK; Tenovuo, O1
Cramer, H; Geiger, J; Jost, S; Milios, E; Mundinger, F; Reuner, C1
Sivam, SP1
Blessing, WW; Blumbergs, PC; Gai, WP; Geffen, LB; Halliday, GM1
Barker, R2
Bogerts, B; Zech, M1
Tan, MX1
Graybiel, AM1
Agid, Y; Cesselin, F; Epelbaum, J; Javoy-Agid, F; Taquet, H1
Halonen, T; Jolkkonen, J; Laakso, M; Laulumaa, V; Riekkinen, P; Soininen, H; Ylinen, A1
Cramer, H; Ernst, A; Kuntzmann, F; Schoenenberger, GA; Strubel, D1
Hunt, SP; Peck, R; Reynolds, GP; Rossor, M; Waters, CM1
Cramer, H; Kuntzmann, F; Rissler, K; Rösler, N; Schaudt, D; Strubel, D1
Brodin, E; Lindefors, N; Segovia, J; Tossman, U; Ungerstedt, U1
Beal, MF; Clevens, RA1
Eng, LF; Forno, LS; Grafe, MR1
Gillman, MA; Sandyk, R1

Reviews

12 review(s) available for substance p and Parkinson Disease

ArticleYear
What substance P might tell us about the prognosis and mechanism of Parkinson's disease?
    Neuroscience and biobehavioral reviews, 2021, Volume: 131

    Topics: alpha-Synuclein; Animals; Brain; Gastrointestinal Tract; Humans; Parkinson Disease; Prognosis; Substance P

2021
The globus pallidus as a target for neuropeptides and endocannabinoids participating in central activities.
    Peptides, 2020, Volume: 124

    Topics: Animals; Endocannabinoids; Enkephalins; Globus Pallidus; Humans; Huntington Disease; Neuropeptides; Parkinson Disease; Substance P

2020
[Continuous subthalamic neurostimulation in Parkinson's disease. Indications and modalities].
    Presse medicale (Paris, France : 1983), 2003, Sep-06, Volume: 32, Issue:28

    Topics: Dopamine; Electric Stimulation Therapy; Electrodes, Implanted; Enkephalins; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Imaging; Parkinson Disease; Patient Selection; Perioperative Care; Referral and Consultation; Risk Factors; Severity of Illness Index; Stereotaxic Techniques; Substance P; Subthalamic Nucleus; Treatment Outcome

2003
Putative peptide neurotransmitters in human neuropathology: a review of topography and clinical implications.
    Clinical neuropathology, 1983, Volume: 2, Issue:2

    Topics: Alzheimer Disease; Brain Mapping; Central Nervous System Diseases; Cholecystokinin; Enkephalins; Humans; Huntington Disease; Limbic System; Nerve Tissue Proteins; Neurotransmitter Agents; Parkinson Disease; Schizophrenia; Substance P; Substance-Related Disorders

1983
Implications of neuropeptides in neurological diseases.
    Peptides, 1984, Volume: 5 Suppl 1

    Topics: Alzheimer Disease; Animals; Brain; Cholecystokinin; Choline O-Acetyltransferase; Endorphins; Epilepsy; Forecasting; Histocytochemistry; Humans; Huntington Disease; Migraine Disorders; Nerve Tissue Proteins; Nervous System Diseases; Pain; Parkinson Disease; Radioimmunoassay; Somatostatin; Substance P; Thyrotropin-Releasing Hormone; Tissue Distribution; Vasopressins

1984
Adenosine receptor antagonists and Parkinson's disease: actions of the A2A receptor in the striatum.
    Advances in neurology, 1999, Volume: 80

    Topics: Acetylcholine; Animals; Behavior, Animal; Corpus Striatum; Enkephalins; gamma-Aminobutyric Acid; Gene Expression; Humans; Neurotransmitter Agents; Parkinson Disease; Protein Precursors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Substance P

1999
[Development of dyskinesias induced by treatment for Parkinson's disease: potential role of first exposure to L-DOPA (or phenomenon of priming)].
    Revue neurologique, 2000, Volume: 156, Issue:3

    Topics: Animals; Antiparkinson Agents; Biological Transport, Active; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Enkephalins; Haplorhini; Humans; Levodopa; Neural Pathways; Neuronal Plasticity; Neurons, Efferent; Parkinson Disease; Receptors, Dopamine D2; Substance P; Time Factors

2000
Recent advances in research on Parkinsonism.
    Acta neurologica Scandinavica. Supplementum, 1978, Volume: 67

    Topics: Acetylcholinesterase; Adult; Apomorphine; Benserazide; Brain; Bromocriptine; Carbidopa; Dopa Decarboxylase; Dopamine; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans; Levodopa; Norepinephrine; Parkinson Disease; Selegiline; Serotonin; Substance P; Tyrosine 3-Monooxygenase

1978
Substance P and neurodegenerative disorders. A speculative review.
    Neuropeptides, 1991, Volume: 20, Issue:2

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Autoimmunity; Central Nervous System Diseases; Humans; Parkinson Disease; Substance P

1991
[Peptide neurotransmitters and extrapyramidal disorders].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1985, Volume: 18, Issue:4

    Topics: Animals; Basal Ganglia Diseases; Enkephalins; Humans; Huntington Disease; MSH Release-Inhibiting Hormone; Parkinson Disease; Substance P

1985
Neuropeptides in the basal ganglia.
    Research publications - Association for Research in Nervous and Mental Disease, 1986, Volume: 64

    Topics: Animals; Basal Ganglia; Cats; Cattle; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Dopamine; Enkephalin, Methionine; Epidermal Growth Factor; gamma-Aminobutyric Acid; Globus Pallidus; Haplorhini; Humans; Interneurons; Limbic System; Mice; Nerve Tissue Proteins; Neural Pathways; Neurotransmitter Agents; Parkinson Disease; Rats; Substance P; Substantia Nigra; Thalamic Nuclei

1986
Neuropeptides and Parkinson's disease.
    Progress in brain research, 1986, Volume: 66

    Topics: Animals; Brain; Enkephalin, Leucine; Enkephalin, Methionine; Hormones; Humans; Neuropeptides; Parkinson Disease; Somatostatin; Substance P

1986

Other Studies

47 other study(ies) available for substance p and Parkinson Disease

ArticleYear
Serum Substance P Is Increased in Parkinson's Disease and Correlates with Motor Impairment.
    Movement disorders : official journal of the Movement Disorder Society, 2022, Volume: 37, Issue:1

    Topics: Humans; Motor Disorders; Neuropsychological Tests; Parkinson Disease; Substance P

2022
Olfactory Neuron Substance P is Overexpressed in Parkinson's Disease Reflecting Gut Dysfunction.
    Movement disorders : official journal of the Movement Disorder Society, 2023, Volume: 38, Issue:7

    Topics: Humans; Neurons; Olfaction Disorders; Parkinson Disease; Substance P

2023
Effects of a combination treatment of KD5040 and
    BMC complementary and alternative medicine, 2017, Apr-19, Volume: 17, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dyskinesia, Drug-Induced; Enkephalins; Extracellular Signal-Regulated MAP Kinases; Levodopa; Magnoliopsida; Male; Mice, Inbred C57BL; Movement; Parkinson Disease; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-fos; Substance P

2017
Cutaneous neuropathy in Parkinson's disease: a window into brain pathology.
    Acta neuropathologica, 2014, Volume: 128, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Autonomic Pathways; Back; Brain; Female; Fingers; Humans; Leg; Male; Middle Aged; Nerve Degeneration; Neural Conduction; Parkinson Disease; Peripheral Nervous System Diseases; Phosphorylation; Skin; Substance P; Vitamins

2014
Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integration.
    Neurobiology of disease, 2015, Volume: 77

    Topics: Aging; Amphetamine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopaminergic Neurons; Dyskinesia, Drug-Induced; Embryo, Mammalian; Functional Laterality; Levodopa; Neurites; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Recovery of Function; Stem Cell Transplantation; Substance P

2015
Using Gelatin Nanoparticle Mediated Intranasal Delivery of Neuropeptide Substance P to Enhance Neuro-Recovery in Hemiparkinsonian Rats.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; Behavior, Animal; Biomarkers; Caspase 3; Cell Line; Disease Models, Animal; Dopaminergic Neurons; Gelatin; Male; Nanoparticles; Neurotransmitter Agents; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-jun; Rats; Substance P; Tyrosine 3-Monooxygenase

2016
alpha-Synucleinopathy in the human olfactory system in Parkinson's disease: involvement of calcium-binding protein- and substance P-positive cells.
    Acta neuropathologica, 2010, Volume: 119, Issue:6

    Topics: Aged; Aged, 80 and over; alpha-Synuclein; Calcium-Binding Proteins; Case-Control Studies; Cell Count; Cerebral Cortex; Female; Humans; Lewy Bodies; Male; Middle Aged; Neurites; Olfactory Bulb; Olfactory Pathways; Parkinson Disease; Substance P

2010
Dopamine-dependent long-term depression is expressed in striatal spiny neurons of both direct and indirect pathways: implications for Parkinson's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Aug-31, Volume: 31, Issue:35

    Topics: Analysis of Variance; Animals; Avoidance Learning; Biophysical Phenomena; Corpus Striatum; Disease Models, Animal; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Green Fluorescent Proteins; Long-Term Synaptic Depression; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance P

2011
Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases.
    Movement disorders : official journal of the Movement Disorder Society, 2012, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; alpha-Synuclein; Biomarkers; Colon; Female; Humans; Male; Middle Aged; Neurites; Parkinson Disease; Substance P

2012
Impaired efficacy of cough in patients with Parkinson disease.
    Chest, 2003, Volume: 124, Issue:3

    Topics: Aged; Cough; Disease Progression; Female; Humans; Middle Aged; Motor Neurons; Parkinson Disease; Peak Expiratory Flow Rate; Pneumonia, Aspiration; Reflex, Abnormal; Sensory Receptor Cells; Spirometry; Sputum; Substance P

2003
Plasma aminopeptidase activities in Parkinson's disease.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2006, Volume: 38, Issue:11

    Topics: Aged; Aminopeptidases; Angiotensins; Cholecystokinin; Dopamine; Enkephalins; Female; Humans; Male; Middle Aged; Neurotensin; Parkinson Disease; Substance P; Vasopressins

2006
Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease.
    Neuropharmacology, 2008, Volume: 54, Issue:7

    Topics: Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Disease Models, Animal; Dopamine; Feedback; Functional Laterality; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinson Disease; Peptide Fragments; Quinolines; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Serine; Substance P; Sympatholytics; Tyrosine 3-Monooxygenase

2008
Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brains.
    Brain research, 1983, May-23, Volume: 268, Issue:1

    Topics: Aged; Basal Ganglia; Globus Pallidus; Humans; Parkinson Disease; Substance P; Substantia Nigra

1983
Methionine-enkephalin, substance P, and homovanillic acid in the CSF of parkinsonian patients.
    Neurology, 1984, Volume: 34, Issue:4

    Topics: Adult; Aged; Dopamine; Enkephalin, Methionine; Female; Homovanillic Acid; Humans; Male; Middle Aged; Parkinson Disease; Phenylacetates; Substance P

1984
Substance P immunoreactivity in the post-mortem parkinsonian brain.
    Brain research, 1984, Jun-11, Volume: 303, Issue:1

    Topics: Aged; Antipsychotic Agents; Brain Chemistry; Female; Humans; Levodopa; Male; Parkinson Disease; Putamen; Radioimmunoassay; Substance P; Substantia Nigra

1984
Parallel alterations in Met-enkephalin and substance P levels in medial globus pallidus in Parkinson's disease patients.
    Neuroscience letters, 1993, Oct-01, Volume: 160, Issue:2

    Topics: Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Dopamine; Enkephalin, Methionine; Female; Globus Pallidus; Humans; Male; Middle Aged; Parkinson Disease; Radioimmunoassay; Reference Values; Substance P

1993
Lack of ACTH/cortisol and GH responses to intravenously-infused substance P in Parkinson's disease.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:2

    Topics: Adrenocorticotropic Hormone; Blood Pressure; Dose-Response Relationship, Drug; Growth Hormone; Heart Rate; Humans; Hydrocortisone; Infusions, Intravenous; Male; Middle Aged; Parkinson Disease; Prolactin; Radioimmunoassay; Substance P; Thyrotropin

1993
Substance P receptors are differentially affected in Parkinson's and Alzheimer's disease.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Basal Ganglia; Female; Globus Pallidus; Humans; Iodine Radioisotopes; Male; Middle Aged; Neostriatum; Parkinson Disease; Receptors, Neurokinin-1; Substance P; Succinimides

1993
Striosomal arrangement of met-enkephalin and substance P expression in parkinsonism-dementia complex on Guam.
    Acta neuropathologica, 1993, Volume: 85, Issue:4

    Topics: Corpus Striatum; Dementia; Enkephalin, Methionine; Guam; Humans; Immunohistochemistry; Parkinson Disease; Substance P

1993
Striatal expression of substance P and methionin-enkephalin in genes in patients with Parkinson's disease.
    Neuroscience letters, 1995, Oct-27, Volume: 199, Issue:3

    Topics: Aged; Caudate Nucleus; Corpus Striatum; Enkephalin, Methionine; Humans; In Situ Hybridization; Parkinson Disease; Putamen; RNA, Messenger; Substance P

1995
Subgroups of parkinsonian patients differentiated by peptidergic immunostaining of caudate nucleus biopsies.
    Peptides, 1999, Volume: 20, Issue:2

    Topics: Aged; Analysis of Variance; Biopsy; Caudate Nucleus; Enkephalin, Methionine; Female; Humans; Immunohistochemistry; Male; Middle Aged; Motor Skills; Parkinson Disease; Statistics, Nonparametric; Substance P; Tyrosine 3-Monooxygenase

1999
Increased cerebrospinal fluid levels of substance P in patients with amyotrophic lateral sclerosis. Short communication.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:9-10

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Female; Humans; Male; Middle Aged; Parkinson Disease; Peripheral Nervous System Diseases; Substance P

1999
Phenotypical characterization of the neurons expressing the D1 and D2 dopamine receptors in the monkey striatum.
    The Journal of comparative neurology, 2000, Feb-28, Volume: 418, Issue:1

    Topics: Animals; Corpus Striatum; Enkephalins; Glutamate Decarboxylase; Isoenzymes; Macaca fascicularis; Neurons; Parkinson Disease; Phenotype; Protein Precursors; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Substance P

2000
The effects of the traditional chinese medicine, "Banxia Houpo Tang (Hange-Koboku To)" on the swallowing reflex in Parkinson's disease.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2000, Volume: 7, Issue:4

    Topics: Aged; Case-Control Studies; Deglutition; Deglutition Disorders; Drugs, Chinese Herbal; Female; Humans; Male; Parkinson Disease; Plants, Medicinal; Saliva; Substance P

2000
The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice.
    Neuroscience, 2000, Volume: 99, Issue:4

    Topics: Animals; Electron Transport Complex IV; Female; Gene Expression; Globus Pallidus; Glutamate Decarboxylase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neostriatum; Neural Pathways; Neurons; Parkinson Disease; Phenotype; Receptors, Dopamine D2; RNA, Messenger; Substance P; Substantia Nigra; Subthalamic Nucleus

2000
L-DOPA produces strong induction of c-fos messenger RNA in dopamine-denervated cortical and striatal areas of the common marmoset.
    Neuroscience, 2000, Volume: 99, Issue:3

    Topics: Animals; Benzazepines; Blotting, Western; Callithrix; Cerebral Cortex; Corpus Striatum; Denervation; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Antagonists; Enkephalins; Gene Expression; Genes, Immediate-Early; Levodopa; Nerve Degeneration; Oxidopamine; Parkinson Disease; Protein Precursors; Proto-Oncogene Proteins c-fos; Raclopride; Radioligand Assay; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Substance P; Substantia Nigra; Sympatholytics; Tritium

2000
High-frequency stimulation of the subthalamic nucleus selectively reverses dopamine denervation-induced cellular defects in the output structures of the basal ganglia in the rat.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Jun-15, Volume: 22, Issue:12

    Topics: Animals; Basal Ganglia; Behavior, Animal; Corpus Striatum; Dopamine; Electric Stimulation; Electron Transport Complex IV; Enkephalins; Entopeduncular Nucleus; Globus Pallidus; Glutamate Decarboxylase; Isoenzymes; Male; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger; Substance P; Substantia Nigra; Subthalamic Nucleus

2002
[Basal ganglia lesions and neurotransmitters].
    Nihon rinsho. Japanese journal of clinical medicine, 1978, Volume: 36, Issue:1

    Topics: Acetylcholine; Animals; Basal Ganglia; Dopamine; gamma-Aminobutyric Acid; Humans; Huntington Disease; Neurotransmitter Agents; Parkinson Disease; Rabbits; Rats; Substance P; Substantia Nigra

1978
Striatal neuropeptide levels in Parkinson's disease patients.
    Neuroscience letters, 1992, Oct-12, Volume: 145, Issue:2

    Topics: Aged; Cholecystokinin; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Enkephalin, Methionine; Female; Humans; Male; Neuropeptides; Parkinson Disease; Radioimmunoassay; Substance P

1992
Striosomal organization of substance P-like immunoreactivity in parkinsonian patients.
    Neurology, 1992, Volume: 42, Issue:5

    Topics: Aged; Aged, 80 and over; Corpus Striatum; Globus Pallidus; Humans; Immunoenzyme Techniques; Middle Aged; Parkinson Disease; Substance P

1992
Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease.
    Brain research, 1992, May-29, Volume: 581, Issue:2

    Topics: Aged; Aged, 80 and over; Axonal Transport; Calbindin 1; Calbindins; Corpus Striatum; Disease Susceptibility; Female; Humans; Male; Melanins; Mesencephalon; Middle Aged; Neurons; Parkinson Disease; S100 Calcium Binding Protein G; Substance P; Substantia Nigra; Tyrosine 3-Monooxygenase

1992
Loss of brainstem serotonin- and substance P-containing neurons in Parkinson's disease.
    Brain research, 1990, Feb-26, Volume: 510, Issue:1

    Topics: Antibodies, Monoclonal; Brain Stem; Humans; Immunohistochemistry; Parkinson Disease; Raphe Nuclei; Serotonin; Substance P; Vagus Nerve

1990
Immunohistochemical study of the striatal efferents and nigral dopaminergic neurons in parkinsonism-dementia complex on Guam in comparison with those in Parkinson's and Alzheimer's diseases.
    Annals of neurology, 1990, Volume: 27, Issue:5

    Topics: Alzheimer Disease; Calcineurin; Calmodulin-Binding Proteins; Corpus Striatum; Dementia; Dopamine; Enkephalin, Methionine; Guam; Humans; Immunohistochemistry; Neuropeptides; Parkinson Disease; Phosphoprotein Phosphatases; Substance P; Substantia Nigra; Tyrosine 3-Monooxygenase

1990
Brain substance P receptors in Parkinson's disease.
    Advances in neurology, 1990, Volume: 53

    Topics: Aged; Brain; Brain Mapping; Corpus Striatum; Humans; Parkinson Disease; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Substantia Innominata

1990
Ventricular fluid neuropeptides in Parkinson's disease. II. Levels of substance P-like immunoreactivity.
    Neuropeptides, 1991, Volume: 18, Issue:2

    Topics: Adult; Analysis of Variance; Cerebrospinal Fluid Proteins; Chromatography, High Pressure Liquid; Female; Humans; Immunoassay; Male; Middle Aged; Nervous System Diseases; Parkinson Disease; Reference Values; Substance P

1991
Dopamine dependent decrease in enkephalin and substance P levels in basal ganglia regions of postmortem parkinsonian brains.
    Neuropeptides, 1991, Volume: 18, Issue:4

    Topics: Aged; Aged, 80 and over; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Dopamine; Dynorphins; Enkephalins; Frontal Lobe; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Radioimmunoassay; Rats; Serotonin; Substance P

1991
Substance P-containing neurons in the mesopontine tegmentum are severely affected in Parkinson's disease.
    Brain : a journal of neurology, 1991, Volume: 114 ( Pt 5)

    Topics: Aged; Female; Humans; Male; Middle Aged; Neurons; Parkinson Disease; Pons; Substance P; Tegmentum Mesencephali

1991
Methionine-enkephalin and substance P in the basal ganglia of normals, Parkinson patients, Huntington patients, and schizophrenics. A qualitative immunohistochemical study.
    Acta neuropathologica, 1985, Volume: 68, Issue:1

    Topics: Adult; Aged; Basal Ganglia; Enkephalin, Methionine; Female; Humans; Huntington Disease; Immunoenzyme Techniques; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Postencephalitic; Schizophrenia; Substance P

1985
Substance P and Parkinson's disease: a causal relationship?
    Journal of theoretical biology, 1986, Jun-07, Volume: 120, Issue:3

    Topics: Animals; Brain; Humans; Neurons; Parkinson Disease; Peptides; Protein Precursors; Rats; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Substance P; Tachykinins

1986
Somatostatin-like immunoreactivity in the cerebrospinal fluid of patients with Parkinson's disease and its relation to dementia.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:12

    Topics: Acetylcholinesterase; Adult; Aged; Aged, 80 and over; Dementia; Female; Homovanillic Acid; Humans; Male; Middle Aged; Parkinson Disease; Peptides; Substance P

1986
Comparison of DSIP- (delta sleep-inducing peptide) and P-DSIP-like (phosphorylated) immunoreactivity in cerebrospinal fluid of patients with senile dementia of Alzheimer type, multi-infarct syndrome, communicating hydrocephalus and Parkinson's disease.
    Journal of neurology, 1987, Volume: 235, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Delta Sleep-Inducing Peptide; Dementia; Female; Humans; Hydrocephalus; Male; Middle Aged; Parkinson Disease; Peptides; Phosphoproteins; Radioimmunoassay; Substance P

1987
Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea.
    Neuroscience, 1988, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia; Catecholamines; Cell Count; Enkephalins; Female; Humans; Huntington Disease; Immunohistochemistry; Male; Middle Aged; Parkinson Disease; Substance P; Substantia Nigra

1988
Immunoreactive substance P and somatostatin in the cerebrospinal fluid of senile parkinsonian patients.
    European neurology, 1989, Volume: 29, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Parkinson Disease; Somatostatin; Substance P

1989
Tissue levels and in vivo release of tachykinins and GABA in striatum and substantia nigra of rat brain after unilateral striatal dopamine denervation.
    Experimental brain research, 1989, Volume: 74, Issue:3

    Topics: Animals; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Neurokinin A; Oxidopamine; Parkinson Disease; Rats; Rats, Inbred Strains; Substance P; Substantia Nigra; Tachykinins

1989
Substance P-like immunoreactivity in brains with pathological features of Parkinson's and Alzheimer's diseases.
    Brain research, 1989, May-08, Volume: 486, Issue:2

    Topics: Aged; Alzheimer Disease; Brain; Female; Humans; Immunohistochemistry; Male; Parkinson Disease; Substance P

1989
Immunocytochemical studies of substance P and Met-enkephalin in the basal ganglia and substantia nigra in Huntington's, Parkinson's and Alzheimer's diseases.
    Journal of neuropathology and experimental neurology, 1985, Volume: 44, Issue:1

    Topics: Aged; Alzheimer Disease; Basal Ganglia; Enkephalin, Methionine; Humans; Huntington Disease; Immunochemistry; Middle Aged; Parkinson Disease; Radioimmunoassay; Substance P

1985
Opioid hypofunction in Parkinson's disease.
    Medical hypotheses, 1985, Volume: 16, Issue:2

    Topics: Acetylcholine; Animals; Brain; Dopamine; Endorphins; gamma-Aminobutyric Acid; Neurotransmitter Agents; Parkinson Disease; Rats; Serotonin; Substance P; Synaptic Transmission

1985