Page last updated: 2024-08-23

substance p and Pain, Postoperative

substance p has been researched along with Pain, Postoperative in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's3 (12.50)18.2507
2000's2 (8.33)29.6817
2010's17 (70.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, JL; Qiao, LN; Tan, LH; Yang, HL; Yang, YS; Zhai, X1
Coetzee, JF; Gorden, PJ; Ji, J; Kleinhenz, MD; Van Engen, NK; Walsh, P1
Liu, P; Shi, J; Sun, K; Wu, S; Xu, T; Xu, X; Zhang, Y1
Arabacı, T; Arslan, H; Doğanay Yıldız, E; Köseoğlu, S; Savran, L; Yıldız, DA1
Chen, YW; Chiu, CC; Hung, CH; Lin, HT; Liu, CC; Wang, JJ1
Bäckryd, E; Gerdle, B; Ghafouri, B; Larsson, B1
Ganev, EG; Hiruma-Lima, CA; Martins, DF; Mazzardo-Martins, L; Nishijima, CM; Rocha, LR; Santos, AR1
Chen, YW; Hung, CH; Lin, MF; Tzeng, JI; Wang, JJ2
Allan, ND; Burwash, L; Matheson-Bird, H; Olson, ME; Ralston, B1
Freeman, TA; Isaza, JE; Kurtz, SM; Lanman, TH; Steinbeck, MJ; Veruva, SY1
Knutson, KL; Noorbaloochi, S; Singh, JA1
Hiller, JG; Ho, KM; Kuruvilla, N; Millen, R; Ramsay, R; Riedel, B; Sampurno, S1
Clark, DJ; Guo, TZ; Kingery, WS; Qiao, Y; Sahbaie, P; Shi, X; Yeomans, DC1
Chen, SP; Gao, YH; Liu, JL; Qiao, LN; Wang, JY; Yang, YS1
Angst, MS; Carvalho, B; Clark, DJ; Yeomans, DC1
Kawamata, M1
Buvanendran, A; Della Valle, CJ; Kroin, JS; Moric, M; Tuman, KJ1
Tan, KJ; Wong, HK1
Hartvig, P; Sakurada, T; Tamsen, A; Terenius, L; Wahlström, A1
Pritchett, JW1
Field, MJ; Gonzalez, MI; Holloman, EF; Hughes, J; Oles, RJ; Singh, L1
Nørholt, SE1
Folkesson, R; Hartvig, P; Sjöström, S; Tamsen, A; Terenius, L1

Reviews

2 review(s) available for substance p and Pain, Postoperative

ArticleYear
[Mechanisms of postoperative pain].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59 Suppl

    Topics: Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Emotions; Humans; Lectins; Pain, Postoperative; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Receptors, Purinergic P2X3; Sensation; Substance P; Substantia Gelatinosa

2010
Treatment of acute pain following removal of mandibular third molars. Use of the dental pain model in pharmacological research and development of a comparable animal model.
    International journal of oral and maxillofacial surgery, 1998, Volume: 27 Suppl 1

    Topics: Acute Disease; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bite Force; Calcitonin Gene-Related Peptide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Mandible; Molar, Third; Morphine; Movement; Neuropeptides; Pain Threshold; Pain, Postoperative; Piroxicam; Rats; Substance P; Tooth Extraction

1998

Trials

7 trial(s) available for substance p and Pain, Postoperative

ArticleYear
Effects of transdermal flunixin meglumine on pain biomarkers at dehorning in calves.
    Journal of animal science, 2017, Volume: 95, Issue:5

    Topics: Administration, Cutaneous; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cattle; Clonixin; Horns; Hydrocortisone; Male; Nociception; Pain Management; Pain, Postoperative; Substance P

2017
The effect of photobiomodulation on total amount of substance P in gingival crevicular fluid: placebo-controlled randomized clinical trial.
    Lasers in medical science, 2019, Volume: 34, Issue:3

    Topics: Adult; Female; Gingival Crevicular Fluid; Humans; Low-Level Light Therapy; Male; Pain, Postoperative; Periodontitis; Placebos; Preoperative Care; Substance P

2019
Cytokine and neuropeptide levels are associated with pain relief in patients with chronically painful total knee arthroplasty: a pilot study.
    BMC musculoskeletal disorders, 2017, 01-14, Volume: 18, Issue:1

    Topics: Aged; Arthroplasty, Replacement, Knee; Biomarkers; Chemokines; Female; Humans; Male; Pain, Postoperative; Pilot Projects; Substance P

2017
Impact of celecoxib on inflammation during cancer surgery: a randomized clinical trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2017, Volume: 64, Issue:5

    Topics: Aged; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Follow-Up Studies; Humans; Inflammation; Male; Middle Aged; Neoplasms; Pain, Postoperative; Prospective Studies; Substance P

2017
Continuous subcutaneous instillation of bupivacaine compared to saline reduces interleukin 10 and increases substance P in surgical wounds after cesarean delivery.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:6

    Topics: Adult; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; California; Cesarean Section; Dinoprostone; Down-Regulation; Elective Surgical Procedures; Enzyme-Linked Immunosorbent Assay; Exudates and Transudates; Female; Humans; Inflammation Mediators; Infusions, Subcutaneous; Interleukin-10; Nerve Growth Factor; Pain Measurement; Pain, Postoperative; Pregnancy; Sodium Chloride; Subcutaneous Tissue; Substance P; Time Factors; Treatment Outcome; Up-Regulation

2010
Cerebrospinal fluid neurotransmitter changes during the perioperative period in patients undergoing total knee replacement: a randomized trial.
    Anesthesia and analgesia, 2012, Volume: 114, Issue:2

    Topics: Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, Knee; Calcitonin Gene-Related Peptide; Chicago; Drug Administration Schedule; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Norepinephrine; Pain Measurement; Pain, Postoperative; Perioperative Period; Pregabalin; Prospective Studies; Spinal Puncture; Substance P; Time Factors; Treatment Outcome

2012
Cerebrospinal fluid concentrations of substance P and (met)enkephalin-Arg6-Phe7 during surgery and patient-controlled analgesia.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:10

    Topics: Adult; Anesthesia, General; Enkephalin, Methionine; Female; Humans; Male; Pain, Postoperative; Substance P; Surgical Procedures, Operative; Time Factors

1988

Other Studies

15 other study(ies) available for substance p and Pain, Postoperative

ArticleYear
Effect of electroacupuncture on thermal pain threshold and expression of calcitonin-gene related peptide, substance P and γ-aminobutyric acid in the cervical dorsal root ganglion of rats with incisional neck pain.
    Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2017, Volume: 35, Issue:4

    Topics: Acupuncture Analgesia; Acupuncture Points; Animals; Calcitonin Gene-Related Peptide; Electroacupuncture; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Male; Neck Pain; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Substance P

2017
Occurrence of substance P and neurokinin receptors during the early phase of spinal fusion.
    Molecular medicine reports, 2018, Volume: 17, Issue:5

    Topics: Animals; Male; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Spinal Fusion; Substance P; Time Factors

2018
Ultrasound therapy reduces persistent post-thoracotomy tactile allodynia and spinal substance P expression in rats.
    Regional anesthesia and pain medicine, 2019, Volume: 44, Issue:5

    Topics: Animals; Gene Expression; Hyperalgesia; Male; Pain Measurement; Pain, Postoperative; Random Allocation; Rats; Rats, Sprague-Dawley; Substance P; Thoracotomy; Ultrasonic Therapy

2019
Do low levels of beta-endorphin in the cerebrospinal fluid indicate defective top-down inhibition in patients with chronic neuropathic pain? A cross-sectional, comparative study.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:1

    Topics: Adult; Analgesics; beta-Endorphin; Biomarkers; Chronic Pain; Clinical Trials as Topic; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Neuralgia; Pain, Intractable; Pain, Postoperative; Substance P

2014
Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.
    European journal of pharmacology, 2014, Aug-05, Volume: 736

    Topics: Acute Pain; Acyclic Monoterpenes; Analgesics; Animals; Capsaicin; Chronic Pain; Excitatory Amino Acids; Formaldehyde; Glutamic Acid; Hyperalgesia; Ischemia; Ketanserin; Male; Mice; Monoterpenes; Neuralgia; Pain, Postoperative; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists; Stomach Ulcer; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2014
Forced treadmill running suppresses postincisional pain and inhibits upregulation of substance P and cytokines in rat dorsal root ganglion.
    The journal of pain, 2014, Volume: 15, Issue:8

    Topics: Analysis of Variance; Animals; Cytokines; Disease Models, Animal; Exercise Test; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Interleukin-1beta; Interleukin-6; Male; Pain Measurement; Pain Threshold; Pain, Postoperative; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Substance P; Time Factors

2014
Transcutaneous electrical nerve stimulation attenuates postsurgical allodynia and suppresses spinal substance P and proinflammatory cytokine release in rats.
    Physical therapy, 2015, Volume: 95, Issue:1

    Topics: Animals; Cytokines; Hyperalgesia; Male; Models, Animal; Pain, Postoperative; Rats, Sprague-Dawley; Spinal Cord; Substance P; Transcutaneous Electric Nerve Stimulation; Up-Regulation

2015
Efficacy of oral meloxicam suspension for prevention of pain and inflammation following band and surgical castration in calves.
    BMC veterinary research, 2016, Jun-13, Volume: 12, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Heart Rate; Hydrocortisone; Inflammation; Male; Meloxicam; Orchiectomy; Pain Measurement; Pain, Postoperative; Substance P; Thiazines; Thiazoles

2016
Periprosthetic UHMWPE Wear Debris Induces Inflammation, Vascularization, and Innervation After Total Disc Replacement in the Lumbar Spine.
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:5

    Topics: Adult; Biopsy; Cytokines; Device Removal; Discitis; Female; Humans; Immunohistochemistry; Inflammation Mediators; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; Lumbar Vertebrae; Macrophages; Male; Middle Aged; Neovascularization, Pathologic; Pain Measurement; Pain, Postoperative; Polyethylenes; Prosthesis Design; Reoperation; Risk Factors; Stress, Mechanical; Substance P; Time Factors; Total Disc Replacement; Treatment Outcome; United States; Vascular Endothelial Growth Factor A; Young Adult

2017
Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision.
    Pain, 2009, Volume: 145, Issue:3

    Topics: Analysis of Variance; Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hyperalgesia; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factor; Neurokinin-1 Receptor Antagonists; Pain Measurement; Pain Threshold; Pain, Postoperative; Piperidines; Protein Precursors; Signal Transduction; Substance P; Tachykinins; Time Factors

2009
[Effects of electroacupuncture at "Futu" (LI 18) on the immunoactivity of substance P, 5-HT 1 AR, etc. of the cervical spinal dorsal horn in rats with neck incision pain].
    Zhen ci yan jiu = Acupuncture research, 2010, Volume: 35, Issue:2

    Topics: Acupuncture Points; Animals; Cyclooxygenase 1; Electroacupuncture; Male; Models, Animal; Pain, Postoperative; Random Allocation; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Neurokinin-1; Spinal Cord; Substance P

2010
Effects of corticosteroids on nerve root recovery after spinal nerve root compression.
    Clinical orthopaedics and related research, 2002, Issue:403

    Topics: Adrenal Cortex Hormones; Animals; Cats; CD4 Antigens; CD5 Antigens; Decompression, Surgical; Disease Models, Animal; Ganglia, Spinal; Pain, Postoperative; Radiculopathy; Spinal Nerve Roots; Substance P

2002
Postoperative demand for analgesics in relation to individual levels of endorphins and substance P in cerebrospinal fluid.
    Pain, 1982, Volume: 13, Issue:2

    Topics: Adult; Endorphins; Female; Humans; Injections, Intravenous; Male; Meperidine; Middle Aged; Pain, Postoperative; Self Administration; Substance P

1982
Substance P level in synovial fluid may predict pain relief after knee replacement.
    The Journal of bone and joint surgery. British volume, 1997, Volume: 79, Issue:1

    Topics: Aged; Aged, 80 and over; Female; Humans; Knee Prosthesis; Male; Middle Aged; Osteoarthritis; Pain, Postoperative; Prognosis; Substance P; Synovial Fluid

1997
Evaluation of PD 154075, a tachykinin NK1 receptor antagonist, in a rat model of postoperative pain.
    European journal of pharmacology, 1998, Mar-05, Volume: 344, Issue:2-3

    Topics: Anesthetics; Animals; Excitatory Amino Acid Antagonists; Isoflurane; Male; Pain Threshold; Pain, Postoperative; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P; Tryptophan

1998