Page last updated: 2024-08-23

substance p and Osteoarthritis

substance p has been researched along with Osteoarthritis in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.04)18.7374
1990's12 (24.49)18.2507
2000's13 (26.53)29.6817
2010's16 (32.65)24.3611
2020's7 (14.29)2.80

Authors

AuthorsStudies
Bauer, RJ; Eitner, A; Grässel, S; Johnstone, B; König, M; Stöckl, S1
Adachi, N; Ishikawa, M; Kanemitsu, M; Miyaki, S; Nakasa, T; Nekomoto, A; Shirakawa, Y; Yimiti, D1
Ahn, W; Han, SH; Jung, BS; Kim, DK; Kim, IS; Ko, KR; Lee, H; Lee, S1
Beaudry, F; Bédard, A; Bouet, E; Delsart, A; Frezier, M; Gaumond, I; Guillot, M; Keita-Alassane, S; Lecomte, R; Lussier, B; Marchand, S; Martel-Pelletier, J; Moreau, M; Otis, C; Pelletier, JP; Troncy, E1
Adachi, N; Ikuta, Y; Ishikawa, M; Miyaki, S; Nakasa, T; Nekomoto, A; Shirakawa, Y; Tokumoto, M1
Jain, M; Joharapurkar, A; Patel, V1
He, J; Zheng, S1
Chen, YJ; Greenhill, C; Ivanusic, JJ; Kim, DH; Nencini, S; Ringuet, M1
Heikkilä, HM; Hielm-Björkman, AK; Innes, JF; Laitinen-Vapaavuori, OM1
Kashiwakura, JI; Kuroda, K; Mishima, S; Okamura, Y; Okayama, Y; Saito, S; Sasaki-Sakamoto, T; Tokuhashi, Y; Toyoshima, S1
Grässel, S; Muschter, D1
Beaudry, F; Guillot, M; Martel-Pelletier, J; Moreau, M; Otis, C; Pelletier, JP; Troncy, E1
Frallonardo, P; Lorenzin, MG; Oliviero, F; Ortolan, A; Punzi, L; Ramonda, R; Scanu, A1
Beaudry, F; Bertaim, T; Del Castillo, JR; Gauvin, D; Martel-Pelletier, J; Moreau, M; Otis, C; Pelletier, JP; Rialland, P; Troncy, E1
Matsuo, S; Murakami, K; Nakagawa, H; Nishimura, K1
Lisowska, B; Lisowski, A; Siewruk, K1
Jeon, SJ; Jung, Y; Kim, JE; Kim, SH; Kim, SJ1
Chen, J; Li, Z; Liu, Y; Wang, B; Wang, X; Xiao, J; Yu, W1
Bobrik, V; Fassold, A; Grifka, J; Kessler, S; Koeck, FX; Straub, RH1
Flood, J1
Beaudry, F; Ferland, CE; Pailleux, F; Vachon, P1
Ahmed, AS; Ahmed, M; Bakalkin, G; Erlandsson-Harris, H; Li, J; Stark, A1
Vilensky, JA; Witt, KL1
Beaudry, F; Ferland, CE; Vachon, P1
Kaneyama, K; Miyamaru, M; Nishimura, M; Segami, N; Suzuki, T1
de Miguel, E; Hernanz, A; Martín-Mola, E; Medina, S1
Ordeberg, G1
Cheng, TO1
Fujimura, K; Kaneyama, K; Nagao, T; Sato, J; Segami, N; Yoshimura, H1
Davis, F; Ellman, M; Forsyth, CB; Im, HJ; Kim, GH; Li, X; Muddasani, P; Rangan, J; Thonar, EJ1
Arnalich, F; de Miguel, E; Gijon-Banos, J; Hernanz, A; Martinez, M; Perez-Ayala, C; Vazquez, JJ1
Alstergren, P; Appelgren, A; Appelgren, B; Kopp, S; Lundeberg, T; Theodorsson, E1
Arnalich, F; De Miguel, E; Gijon, J; Hernanz, A; Perez-Ayala, C; Romera, N1
Bruxelle, J; Cesselin, F; Laoussadi, S; Mauborgne, A; Menkes, CJ; Renoux, M1
Pritchett, JW1
Fortier, LA; Nixon, AJ1
Iannone, F; Lapadula, G1
Cook, JA; Vilensky, JA1
Agarwal, RK; Chandna, VK; Kirker-Head, CA; Kumar, MS; Morris, EA; O'Callaghan, MW; Rand, W; Tidwell, A1
Creamer, P1
Jüsten, HP; Miller, LE; Schölmerich, J; Straub, RH1
Hirabayashi, K; Inoue, H; Kajigaya, H; Koshihara, Y; Oda, H; Shimoyama, Y; Yamamoto, S1
Goss, AN; Tahmasebi-Sarvestani, A; Tedman, R1
Grifka, J; Miller, LE; Schölmerich, J; Straub, RH1
Chiu, B; Inman, RD; Marshall, KW1
Matucci-Cerinic, M; Partsch, G1
Ekblom, A; Hansson, P; Holmlund, A; Lind, J; Lundeberg, T; Theodorsson, E1
Cagnoni, M; Del Bianco, E; Geppetti, P; Marabini, S; Marchesoni, A; Matucci-Cerinic, M; Partsch, G; Tosi, S1
Badalamente, MA; Cherney, SB1

Reviews

9 review(s) available for substance p and Osteoarthritis

ArticleYear
Substance P, A Promising Therapeutic Target in Musculoskeletal Disorders.
    International journal of molecular sciences, 2022, Feb-26, Volume: 23, Issue:5

    Topics: Humans; Musculoskeletal Diseases; Neurokinin-1 Receptor Antagonists; Osteoarthritis; Receptors, Neurokinin-1; Substance P

2022
Therapeutic Potential of Diacerein in Management of Pain.
    Current drug research reviews, 2022, Volume: 14, Issue:3

    Topics: Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cytokines; Glutamates; Histamine; Humans; Matrix Metalloproteinases; Nitric Oxide; Osteoarthritis; Pain; Prostaglandins; Substance P; Transient Receptor Potential Channels

2022
Peripheral Nerve Fibers and Their Neurotransmitters in Osteoarthritis Pathology.
    International journal of molecular sciences, 2017, Apr-28, Volume: 18, Issue:5

    Topics: Calcitonin Gene-Related Peptide; Chondrocytes; Humans; Neuropeptides; Neurotransmitter Agents; Osteoarthritis; Peripheral Nerves; Receptors, Adrenergic; Substance P; Vasoactive Intestinal Peptide

2017
Pain and microcrystalline arthritis.
    Reumatismo, 2014, Jun-06, Volume: 66, Issue:1

    Topics: Animals; Arthritis, Gouty; Calcium Pyrophosphate; Chronic Pain; Crystallization; Dinoprostone; Disease Models, Animal; Humans; Inflammation Mediators; Interleukin-1beta; Kinins; Musculoskeletal Pain; Nociceptors; Osteoarthritis; Quality of Life; Rats; Substance P; TRPV Cation Channels; Uric Acid

2014
The role of acetaminophen in the treatment of osteoarthritis.
    The American journal of managed care, 2010, Volume: 16 Suppl Management

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Endorphin; Humans; Nitric Oxide; Osteoarthritis; Substance P

2010
The anatomy of osteoarthritic joint pain.
    Clinical anatomy (New York, N.Y.), 2014, Volume: 27, Issue:3

    Topics: Calcitonin Gene-Related Peptide; Humans; Joints; Nociception; Nociceptive Pain; Osteoarthritis; Substance P

2014
Characterization of joint pain in human OA.
    Novartis Foundation symposium, 2004, Volume: 260

    Topics: Arthralgia; Humans; Hyperalgesia; Nociceptors; Osteoarthritis; Pain Threshold; Peripheral Nervous System Diseases; Substance P

2004
Neurogenic acceleration of osteoarthritis.
    Current opinion in rheumatology, 1998, Volume: 10, Issue:3

    Topics: Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Capsaicin; Diabetes Mellitus, Experimental; Electrophysiology; Humans; Nervous System; Neuropeptides; Osteoarthritis; Proprioception; Substance P

1998
Osteoarthritis pain and its treatment.
    Current opinion in rheumatology, 2000, Volume: 12, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthroplasty, Replacement; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Exercise Therapy; Glucosamine; Humans; Isoenzymes; Membrane Proteins; Nitric Oxide; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Substance P

2000

Trials

1 trial(s) available for substance p and Osteoarthritis

ArticleYear
The effect of intra-articular botulinum toxin A on substance P, prostaglandin E
    BMC veterinary research, 2017, Mar-21, Volume: 13, Issue:1

    Topics: Animals; Arthralgia; Botulinum Toxins, Type A; Dinoprostone; Dog Diseases; Dogs; Double-Blind Method; Female; Injections, Intra-Articular; Male; Osteoarthritis; Pain; Pain Management; Substance P; Synovial Fluid; Treatment Outcome; Tumor Necrosis Factor-alpha

2017

Other Studies

39 other study(ies) available for substance p and Osteoarthritis

ArticleYear
Substance P and Alpha-Calcitonin Gene-Related Peptide Differentially Affect Human Osteoarthritic and Healthy Chondrocytes.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Aged; Apoptosis; Calcitonin Gene-Related Peptide; Cartilage, Articular; Cells, Cultured; Chondrocytes; Female; Humans; Male; Middle Aged; Osteoarthritis; Signal Transduction; Substance P

2021
Therapeutic effect of targeting Substance P on the progression of osteoarthritis.
    Modern rheumatology, 2022, Oct-15, Volume: 32, Issue:6

    Topics: Animals; Aprepitant; Cartilage, Articular; Disease Models, Animal; Humans; Mice; Osteoarthritis; Phosphates; Substance P; X-Ray Microtomography

2022
Estrogenic impregnation alters pain expression: analysis through functional neuropeptidomics in a surgical rat model of osteoarthritis.
    Naunyn-Schmiedeberg's archives of pharmacology, 2022, Volume: 395, Issue:6

    Topics: Animals; Calcitonin Gene-Related Peptide; Estradiol; Female; Osteoarthritis; Pain; Prospective Studies; Rats; Rats, Sprague-Dawley; Substance P

2022
The role of substance P on maintaining ligament homeostasis by inhibiting endochondral ossification during osteoarthritis progression.
    Connective tissue research, 2023, Volume: 64, Issue:1

    Topics: Animals; Cartilage, Articular; Chondrocytes; Homeostasis; Humans; Matrix Metalloproteinase 13; Mice; Osteoarthritis; Osteogenesis; Posterior Cruciate Ligament; Substance P

2023
NF-κB Phosphorylation Inhibition Prevents Articular Cartilage Degradation in Osteoarthritis Rats via 2-Aminoquinoline.
    Medical science monitor : international medical journal of experimental and clinical research, 2020, Jan-24, Volume: 26

    Topics: Aminoquinolines; Animals; Cartilage, Articular; Cytokines; Dinoprostone; Edema; Extremities; Joints; Male; Matrix Metalloproteinase 13; NF-kappa B; Osteoarthritis; Phosphorylation; Rats, Wistar; Receptors, Purinergic P2X7; Signal Transduction; Substance P

2020
Mechanisms of nerve growth factor signaling in bone nociceptors and in an animal model of inflammatory bone pain.
    Molecular pain, 2017, Volume: 13

    Topics: Action Potentials; Animals; Antibodies; Bone and Bones; Calcitonin Gene-Related Peptide; Disease Models, Animal; Freund's Adjuvant; Male; NAV1.8 Voltage-Gated Sodium Channel; NAV1.9 Voltage-Gated Sodium Channel; Nerve Growth Factor; Nociceptors; Osteoarthritis; Pain; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P; TRPV Cation Channels; Ubiquitin Thiolesterase

2017
The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis.
    Allergology international : official journal of the Japanese Society of Allergology, 2017, Volume: 66S

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Biomarkers; Cells, Cultured; Cytokines; Female; Fluorescent Antibody Technique; Gene Expression; Humans; Inflammation Mediators; Male; Mast Cells; Middle Aged; Osteoarthritis; RNA, Messenger; Substance P; Synoviocytes

2017
Spinal neuropeptide modulation, functional assessment and cartilage lesions in a monosodium iodoacetate rat model of osteoarthritis.
    Neuropeptides, 2017, Volume: 65

    Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cartilage Diseases; Disease Models, Animal; Female; Iodoacetic Acid; Neuropeptides; Nociception; Osteoarthritis; Pain Threshold; Rats, Sprague-Dawley; Somatostatin; Spinal Cord; Stifle; Substance P

2017
Association between sensitisation and pain-related behaviours in an experimental canine model of osteoarthritis.
    Pain, 2014, Volume: 155, Issue:10

    Topics: Analgesics; Animals; Behavior, Animal; Diphosphonates; Dogs; Osteoarthritis; Pain; Pain Measurement; Pain Threshold; Prealbumin; Spinal Cord; Substance P

2014
Changes in peptidergic fiber density in the synovium of mice with collagenase-induced acute arthritis.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:6

    Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Collagenases; Knee Joint; Male; Mice; Mice, Inbred C57BL; Nerve Fibers; Osteoarthritis; Substance P; Synovial Membrane

2015
Substance P and Chronic Pain in Patients with Chronic Inflammation of Connective Tissue.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Arthritis, Rheumatoid; Chronic Pain; Connective Tissue; Female; Humans; Inflammation; Male; Middle Aged; Osteoarthritis; Substance P; Synovial Fluid; Synovial Membrane

2015
Therapeutic effects of neuropeptide substance P coupled with self-assembled peptide nanofibers on the progression of osteoarthritis in a rat model.
    Biomaterials, 2016, Volume: 74

    Topics: Amino Acid Sequence; Animals; Disease Models, Animal; Disease Progression; In Situ Nick-End Labeling; Molecular Sequence Data; Nanofibers; Osteoarthritis; Rats; Real-Time Polymerase Chain Reaction; Substance P; X-Ray Microtomography

2016
Correlation between neuropeptide distribution, cancellous bone microstructure and joint pain in postmenopausal women with osteoarthritis and osteoporosis.
    Neuropeptides, 2016, Volume: 56

    Topics: Aged; Arthralgia; Calcitonin Gene-Related Peptide; Cancellous Bone; Female; Humans; Middle Aged; Neuropeptide Y; Neuropeptides; Osteoarthritis; Osteoporosis, Postmenopausal; Pain Measurement; Pain Perception; Postmenopause; Substance P; Vasoactive Intestinal Peptide

2016
Marked loss of sympathetic nerve fibers in chronic Charcot foot of diabetic origin compared to ankle joint osteoarthritis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2009, Volume: 27, Issue:6

    Topics: Adrenergic Fibers; Aged; Ankle Joint; Arthrodesis; Arthropathy, Neurogenic; Diabetic Foot; Female; Foot Bones; Humans; Male; Middle Aged; Osteoarthritis; Semaphorins; Sensory Receptor Cells; Skin; Substance P; Sympathetic Nervous System; Synovial Membrane

2009
Determination of specific neuropeptides modulation time course in a rat model of osteoarthritis pain by liquid chromatography ion trap mass spectrometry.
    Neuropeptides, 2011, Volume: 45, Issue:6

    Topics: Animals; Calcitonin Gene-Related Peptide; Chromatography, Liquid; Disease Models, Animal; Dynorphins; Enzyme Inhibitors; Humans; Iodoacetic Acid; Knee Joint; Male; Neuropeptides; Osteoarthritis; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Tandem Mass Spectrometry; Time Factors

2011
Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis.
    Pain, 2012, Volume: 153, Issue:1

    Topics: Animals; Arthritis, Experimental; Calcitonin Gene-Related Peptide; Cartilage, Articular; Cysteine Proteinase Inhibitors; Female; Ganglia, Spinal; Knee Joint; Leupeptins; Matrix Metalloproteinase 3; Osteoarthritis; Pain; Pain Measurement; Rats; Rats, Inbred Lew; Substance P

2012
Antinociceptive effects of eugenol evaluated in a monoiodoacetate-induced osteoarthritis rat model.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:9

    Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Clove Oil; Disease Models, Animal; Dynorphins; Eugenol; Gait; Hyperalgesia; Iodoacetic Acid; Knee Joint; Male; Osteoarthritis; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2012
Relationships between pain-related mediators and both synovitis and joint pain in patients with internal derangements and osteoarthritis of the temporomandibular joint.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 94, Issue:3

    Topics: Adolescent; Adult; Aged; Arthralgia; Bradykinin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Facial Pain; Female; Humans; Inflammation Mediators; Joint Dislocations; Leukotriene B4; Male; Middle Aged; Neurotransmitter Agents; Nociceptors; Osteoarthritis; Serotonin; Statistics, Nonparametric; Substance P; Synovial Fluid; Synovitis; Temporomandibular Joint Disorders

2002
Effect of calcitonin gene-related peptide, neuropeptide Y, substance P, and vasoactive intestinal peptide on interleukin-1beta, interleukin-6 and tumor necrosis factor-alpha production by peripheral whole blood cells from rheumatoid arthritis and osteoart
    Regulatory peptides, 2003, Aug-15, Volume: 115, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Cytokines; Dose-Response Relationship, Drug; Female; Humans; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Middle Aged; Neuropeptide Y; Osteoarthritis; Peptides; Substance P; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide

2003
Acupuncture treatment for musculoskeletal chest pain.
    International journal of cardiology, 2007, Sep-14, Volume: 121, Issue:1

    Topics: Acupuncture Therapy; Chest Pain; Fibromyalgia; Humans; Keratan Sulfate; Osteoarthritis; Serotonin; Substance P

2007
Prognostic factors in arthrocentesis of the temporomandibular joint: Comparison of bradykinin, leukotriene B4, prostaglandin E2, and substance P level in synovial fluid between successful and unsuccessful cases.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007, Volume: 65, Issue:2

    Topics: Adolescent; Adult; Aged; Bradykinin; Dinoprostone; Female; Humans; Joint Dislocations; Leukotriene B4; Male; Middle Aged; Osteoarthritis; Pain; Paracentesis; Prognosis; Statistics, Nonparametric; Substance P; Synovial Fluid; Temporomandibular Joint Disorders

2007
Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes.
    Journal of cellular physiology, 2008, Volume: 215, Issue:2

    Topics: Adult; Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chondrocytes; Extracellular Matrix; Fibroblast Growth Factor 2; Humans; Interleukin-1beta; Matrix Metalloproteinase 13; Matrix Metalloproteinases; Metabolism; Mitogen-Activated Protein Kinases; Neurosecretory Systems; NF-kappa B; Osteoarthritis; Proteoglycans; raf Kinases; Receptors, Neurokinin-1; Signal Transduction; Substance P; Synovial Fluid; Time Factors; Up-Regulation

2008
Neuropeptides and interleukin-6 in human joint inflammation relationship between intraarticular substance P and interleukin-6 concentrations.
    Neuroscience letters, 1994, Apr-11, Volume: 170, Issue:2

    Topics: Arthritis, Rheumatoid; Female; Humans; Immunoenzyme Techniques; Interleukin-6; Knee Joint; Male; Middle Aged; Neuropeptides; Osmolar Concentration; Osteoarthritis; Radioimmunoassay; Substance P

1994
Co-variation of neuropeptide Y, calcitonin gene-related peptide, substance P and neurokinin A in joint fluid from patients with temporomandibular joint arthritis.
    Archives of oral biology, 1995, Volume: 40, Issue:2

    Topics: Adult; Aged; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Male; Middle Aged; Neurokinin A; Neuropeptide Y; Osteoarthritis; Regression Analysis; Spondylitis, Ankylosing; Substance P; Synovial Fluid; Temporomandibular Joint Disorders

1995
Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease.
    British journal of rheumatology, 1993, Volume: 32, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Gout; Humans; Male; Middle Aged; Osteoarthritis; Radioimmunoassay; Substance P; Synovial Fluid; Vasoactive Intestinal Peptide

1993
Substance P levels in the synovium and synovial fluid from patients with rheumatoid arthritis and osteoarthritis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Humans; Middle Aged; Osteoarthritis; Radioimmunoassay; Substance P; Synovial Fluid; Synovial Membrane

1993
Substance P level in synovial fluid may predict pain relief after knee replacement.
    The Journal of bone and joint surgery. British volume, 1997, Volume: 79, Issue:1

    Topics: Aged; Aged, 80 and over; Female; Humans; Knee Prosthesis; Male; Middle Aged; Osteoarthritis; Pain, Postoperative; Prognosis; Substance P; Synovial Fluid

1997
Distributional changes in substance P nociceptive fiber patterns in naturally osteoarthritic articulations.
    The Journal of rheumatology, 1997, Volume: 24, Issue:3

    Topics: Animals; Cartilage, Articular; Horses; Immunohistochemistry; Metacarpophalangeal Joint; Nociceptors; Osteoarthritis; Pain; Radiography; Substance P

1997
Neuropeptides and human osteoarthritis.
    The Journal of rheumatology, 1998, Volume: 25, Issue:2

    Topics: Aged; Chondrocytes; Dipeptidyl Peptidase 4; Enkephalin, Methionine; Flow Cytometry; Gastrin-Releasing Peptide; Humans; Immunohistochemistry; Middle Aged; Neprilysin; Neurotransmitter Agents; Osteoarthritis; Substance P

1998
Concentrations of substance P and prostaglandin E2 in synovial fluid of normal and abnormal joints of horses.
    American journal of veterinary research, 2000, Volume: 61, Issue:6

    Topics: Animals; Dinoprostone; Female; Horse Diseases; Horses; Joint Diseases; Male; Osteoarthritis; Radiography; Radioimmunoassay; Statistics, Nonparametric; Substance P; Synovial Fluid

2000
The loss of sympathetic nerve fibers in the synovial tissue of patients with rheumatoid arthritis is accompanied by increased norepinephrine release from synovial macrophages.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:13

    Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Chronic Disease; Cytokines; Electric Stimulation; Humans; Knee Joint; Macrophages; Middle Aged; Nerve Fibers; Norepinephrine; Osteoarthritis; Sensory Receptor Cells; Substance P; Sympathetic Nervous System; Synovial Membrane

2000
Production of neuropeptide substance P by synovial fibroblasts from patients with rheumatoid arthritis and osteoarthritis.
    Neuroscience letters, 2001, May-11, Volume: 303, Issue:3

    Topics: Arthritis, Rheumatoid; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Fibroblasts; Humans; Immunohistochemistry; Nerve Fibers; Osteoarthritis; Protein Precursors; RNA, Messenger; Substance P; Synovial Membrane; Tachykinins; Transforming Growth Factor beta

2001
The influence of experimentally induced osteoarthrosis on articular nerve fibers of the sheep temporomandibular joint.
    Journal of orofacial pain, 2001,Summer, Volume: 15, Issue:3

    Topics: Analysis of Variance; Animals; Autonomic Nervous System; Calcitonin Gene-Related Peptide; Cicatrix; Cysts; Disease Models, Animal; Fibrosis; Image Processing, Computer-Assisted; Immunohistochemistry; Joint Capsule; Male; Mandibular Condyle; Nerve Fibers; Nerve Tissue Proteins; Neurons, Afferent; Neuropeptide Y; Osteoarthritis; Sheep; Statistics, Nonparametric; Substance P; Synovial Membrane; Temporomandibular Joint; Temporomandibular Joint Disc; Temporomandibular Joint Disorders; Thiolester Hydrolases; Tyrosine 3-Monooxygenase; Ubiquitin Thiolesterase; Vasoactive Intestinal Peptide

2001
Norepinephrine from synovial tyrosine hydroxylase positive cells is a strong indicator of synovial inflammation in rheumatoid arthritis.
    The Journal of rheumatology, 2002, Volume: 29, Issue:3

    Topics: Adrenergic Fibers; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Biomarkers; Cell Count; Cells, Cultured; Humans; Interleukin-6; Interleukin-8; Matrix Metalloproteinase 3; Middle Aged; Norepinephrine; Osteoarthritis; Predictive Value of Tests; Substance P; Synovial Membrane; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2002
Substance P and arthritis: analysis of plasma and synovial fluid levels.
    Arthritis and rheumatism, 1990, Volume: 33, Issue:1

    Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Humans; Joints; Osteoarthritis; Substance P; Synovial Fluid; Wounds and Injuries

1990
Effect of capsaicin on the release of substance P from rheumatoid arthritis and osteoarthritis synoviocytes in vitro.
    Annals of the rheumatic diseases, 1990, Volume: 49, Issue:8

    Topics: Arthritis, Rheumatoid; Capsaicin; Humans; Osteoarthritis; Substance P; Synovial Fluid

1990
Concentrations of neuropeptides substance P, neurokinin A, calcitonin gene-related peptide, neuropeptide Y and vasoactive intestinal polypeptide in synovial fluid of the human temporomandibular joint. A correlation with symptoms, signs and arthroscopic fi
    International journal of oral and maxillofacial surgery, 1991, Volume: 20, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Arthroscopy; Calcitonin Gene-Related Peptide; Cartilage, Articular; Female; Humans; Male; Middle Aged; Neurokinin A; Neuropeptide Y; Neuropeptides; Osteoarthritis; Substance P; Synovial Fluid; Synovitis; Temporomandibular Joint; Temporomandibular Joint Disorders; Vasoactive Intestinal Peptide

1991
Substance P and somatostatin levels in rheumatoid arthritis, osteoarthritis, and psoriatic arthritis synovial fluid.
    Annals of the New York Academy of Sciences, 1991, Volume: 632

    Topics: Arthritis; Arthritis, Rheumatoid; Humans; Osteoarthritis; Psoriasis; Somatostatin; Substance P; Synovial Fluid

1991
Periosteal and vascular innervation of the human patella in degenerative joint disease.
    Seminars in arthritis and rheumatism, 1989, Volume: 18, Issue:4 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Capillaries; Cartilage; Cartilage Diseases; Female; Humans; Immunohistochemistry; Male; Middle Aged; Osteoarthritis; Patella; Periosteum; Serotonin; Substance P

1989