Page last updated: 2024-08-23

substance p and Osteoarthritis of Knee

substance p has been researched along with Osteoarthritis of Knee in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (64.71)29.6817
2010's5 (29.41)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Chen, H; Chen, S; Wang, YY; Yan, XH; Yang, JS; Zhang, GY; Zhang, HB1
Arden, NK; Cicuttini, FM; Cooper, C; Dennison, EM; Doherty, M; Hart, DJ; Jones, G; Laslett, LL; Leaverton, P; Maciewicz, RA; Muir, KR; Rampersaud, E; Soni, A; Spector, TD; Valdes, AM; Walsh, DA; Warner, SC; Zhang, W1
Allam, H; Elgendy, A; Elghoroury, E; Helmy, GA; Mohammed, N; Zikri, EN1
Baier, C; Beckmann, J; Grifka, J; Koeck, FX; Schmitt, M; Stangl, H; Straub, RH1
Higashi, M; Moriya, H; Nakagawa, K; Ogino, S; Sasho, T; Suzuki, M; Takahashi, K; Yamaguchi, S1
Baker, SJ; Bianchi, BR; Faltynek, CR; Gauvin, DM; Han, P; Honore, P; Joshi, SK; Koenig, JR; Kort, ME; Kym, PR; Lewis, GR; Mikusa, JP; Neelands, TR; Perner, RJ; Puttfarcken, PS; Reilly, RM1
Arai, Y; Kawata, M; Kida, Y; Kubo, T; Matsuda, K; Morihara, T; Sakamoto, H; Yoshida, A1
Balzarini, P; Baratelli, E; Bianchi, M; Broggini, M; Ferrario, P; Panerai, AE; Sacerdote, P1
Aeschlimann, A; Gay, RE; Gay, S; Michel, BA; Shen, H; Sprott, H1
Raczyńska-Witońska, G; Wagrowska-Danilewicz, M; Witoński, D1
Gill, SE; Massena de Camin, S; McWilliams, DF; Suri, S; Walsh, DA; Wilson, D1
Balzarini, P; Bianchi, M; Broggini, M; Franchi, S; Sacerdote, P1
Anders, S; Angele, P; Capellino, S; Dirmeier, M; Schubert, T; Straub, RH1
Dalén, T; Forsgren, S; Grimsholm, O; Rantapää-Dahlqvist, S1
Koshino, T; Saito, T1
Cervantes, J; Félix, LV; Garcia, PG; Pavlovich, RI; Vazquez-Vela, G; Villarreal, J1
Bray, RC; Erwin, WM; Salo, PT; Seeratten, RA1

Trials

4 trial(s) available for substance p and Osteoarthritis of Knee

ArticleYear
Evaluation of serum beta-endorphin and substance P in knee osteoarthritis patients treated by laser acupuncture.
    Journal of complementary & integrative medicine, 2018, Jan-05, Volume: 15, Issue:2

    Topics: Acupuncture Points; Acupuncture Therapy; Adult; Aged; beta-Endorphin; Female; Humans; Lasers; Male; Middle Aged; Osteoarthritis, Knee; Prospective Studies; Single-Blind Method; Substance P; Treatment Outcome

2018
Effects of tramadol on synovial fluid concentrations of substance P and interleukin-6 in patients with knee osteoarthritis: comparison with paracetamol.
    International immunopharmacology, 2003, Volume: 3, Issue:13-14

    Topics: Acetaminophen; Administration, Oral; Aged; Double-Blind Method; Female; Humans; Interleukin-6; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Substance P; Synovial Fluid; Time Factors; Tramadol

2003
Analgesic action of acetaminophen in symptomatic osteoarthritis of the knee.
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:6

    Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; beta-Endorphin; Biomarkers; Cyclooxygenase 2 Inhibitors; Female; Humans; Knee Joint; Lactones; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Serotonin; Severity of Illness Index; Substance P; Sulfones; Treatment Outcome

2006
Effects of nimesulide on pain and on synovial fluid concentrations of substance P, interleukin-6 and interleukin-8 in patients with knee osteoarthritis: comparison with celecoxib.
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Celecoxib; Double-Blind Method; Female; Humans; Interleukin-6; Interleukin-8; Male; Osteoarthritis, Knee; Pain Measurement; Pyrazoles; Substance P; Sulfonamides; Synovial Fluid; Treatment Outcome

2007

Other Studies

13 other study(ies) available for substance p and Osteoarthritis of Knee

ArticleYear
[Effect of moxibustion and scraping on bioactive substances changes of acupoints in knee osteoarthritis rats].
    Zhen ci yan jiu = Acupuncture research, 2023, Apr-25, Volume: 48, Issue:4

    Topics: Acupuncture Points; Animals; Calcitonin Gene-Related Peptide; Moxibustion; Osteoarthritis, Knee; Rats; Rats, Sprague-Dawley; Serotonin; Substance P

2023
Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene.
    European journal of pain (London, England), 2017, Volume: 21, Issue:7

    Topics: Animals; Arthralgia; Cohort Studies; Female; Genetic Variation; Genotype; Humans; Osteoarthritis, Knee; Pain; Phenotype; Polymorphism, Single Nucleotide; Receptors, Neurokinin-1; Substance P

2017
Predominance of synovial sensory nerve fibers in arthrofibrosis following total knee arthroplasty compared to osteoarthritis of the knee.
    Journal of orthopaedic surgery and research, 2016, Feb-17, Volume: 11

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Female; Fibrosis; Humans; Knee Joint; Male; Middle Aged; Nerve Fibers; Nociceptors; Osteoarthritis, Knee; Severity of Illness Index; Substance P; Synovial Membrane

2016
Detection of pain-related molecules in the subchondral bone of osteoarthritic knees.
    Clinical rheumatology, 2009, Volume: 28, Issue:12

    Topics: Aged; Arthroplasty, Replacement, Knee; Biomarkers; Cartilage, Articular; Cyclooxygenase 2; Female; Femur; Humans; Immunohistochemistry; Knee Joint; Magnetic Resonance Imaging; Male; Menisci, Tibial; Middle Aged; Osteoarthritis, Knee; Pain; Substance P; Tubulin; Tumor Necrosis Factor-alpha

2009
A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model.
    Pain, 2010, Volume: 150, Issue:2

    Topics: Analysis of Variance; Animals; Bradykinin; Calcitonin Gene-Related Peptide; Glutamic Acid; Osteoarthritis, Knee; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Tetrahydronaphthalenes; TRPV Cation Channels

2010
Immunohistochemical analysis of the effects of estrogen on intraarticular neurogenic inflammation in a rat anterior cruciate ligament transection model of osteoarthritis.
    Connective tissue research, 2012, Volume: 53, Issue:3

    Topics: Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Biomarkers; Calcitonin Gene-Related Peptide; Disease Models, Animal; Estradiol; Estrogens; Female; Immunohistochemistry; Neurogenic Inflammation; Osteoarthritis, Knee; Ovariectomy; Rats; Rats, Wistar; Stifle; Substance P; Synovial Membrane; Ubiquitin Thiolesterase

2012
Distribution of substance P nerve fibers in osteoarthritis knee joint.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 2005, Volume: 56, Issue:4

    Topics: Adult; Aged; Female; Fluorescent Antibody Technique, Direct; Humans; Immunoenzyme Techniques; Knee Joint; Male; Nerve Fibers; Osteoarthritis, Knee; Substance P

2005
Neurovascular invasion at the osteochondral junction and in osteophytes in osteoarthritis.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:11

    Topics: Aged; Aged, 80 and over; Calcitonin Gene-Related Peptide; Cartilage, Articular; Female; Humans; Knee Joint; Male; Neovascularization, Pathologic; Nerve Fibers; Osteoarthritis, Knee; Peripheral Nervous System; Severity of Illness Index; Substance P; Ubiquitin Thiolesterase

2007
Lower density of synovial nerve fibres positive for calcitonin gene-related peptide relative to substance P in rheumatoid arthritis but not in osteoarthritis.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Calcitonin Gene-Related Peptide; Female; Humans; Immunohistochemistry; Male; Nerve Fibers; Osteoarthritis, Knee; Substance P; Synovial Membrane; Synovitis

2008
Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the NK-1 receptor.
    Neuropeptides, 2008, Volume: 42, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Bombesin; Enzyme-Linked Immunosorbent Assay; Gastrin-Releasing Peptide; Humans; Immunohistochemistry; In Situ Hybridization; Knee Joint; Middle Aged; Osteoarthritis, Knee; Receptors, Neurokinin-1; RNA, Messenger; Staining and Labeling; Substance P; Synovial Membrane

2008
Distribution of neuropeptides in synovium of the knee with osteoarthritis.
    Clinical orthopaedics and related research, 2000, Issue:376

    Topics: Aged; Calcitonin Gene-Related Peptide; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neuropeptide Y; Neuropeptides; Osteoarthritis, Knee; Substance P; Synovial Membrane

2000
Synovial impingement syndrome and dysphoria articularis syndrome of the knee.
    The journal of knee surgery, 2002,Winter, Volume: 15, Issue:1

    Topics: Adult; Aged; Arthroscopy; Biopsy; Biopsy, Needle; Diagnosis, Differential; Female; Humans; Hyperplasia; Immunohistochemistry; Kinesthesis; Knee Joint; Male; Menisci, Tibial; Middle Aged; Osteoarthritis, Knee; Prospective Studies; Rupture, Spontaneous; Sensitivity and Specificity; Substance P; Syndrome; Synovitis; Tibial Meniscus Injuries

2002
Evidence for a neuropathic contribution to the development of spontaneous knee osteoarthrosis in a mouse model.
    Acta orthopaedica Scandinavica, 2002, Volume: 73, Issue:1

    Topics: Aging; Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Immunohistochemistry; Knee Joint; Male; Mechanoreceptors; Mice; Mice, Inbred C57BL; Neuropeptides; Osteoarthritis, Knee; Risk Assessment; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Substance P

2002