Compounds > substance p
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substance p and Neurogenic Inflammation

substance p has been researched along with Neurogenic Inflammation in 117 studies

Research

Studies (117)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (7.69)18.2507
2000's63 (53.85)29.6817
2010's33 (28.21)24.3611
2020's12 (10.26)2.80

Authors

AuthorsStudies
Doi, M; Imado, E; Irifune, M; Kanematsu, T; Kochi, T; Morioka, N; Mukai, A; Nakamura, Y; Nakata, Y; Onizuka, C; Oue, K; Sakai, N; Shimizu, Y; Yoshida, M1
Huyhn, R; Jung, T; Kim, B; McKemy, DD; Yamaki, S; Yang, C1
Cubała, WJ; Czajkowski, R; Grochocka, M; Marek-Jozefowicz, L; Nedoszytko, B; Slominski, AT; Żmijewski, MA1
Dong, M; Gerhard, R; Goldsmith, JD; Hurdle, JG; Jin, R; Kuziel, GA; Lee, PG; Liu, M; Manion, J; Marreddy, RKR; Musser, MA; Rakoff-Nahoum, S; Rao, M; Shepherd, A; Wang, S; Yuan, K; Zhang, J; Zhao, L1
Chen, R; Chen, Z; Dong, J; Huang, J; Ji, X; Xu, Y; Yan, W; Zhan, C; Zheng, Z; Zhi, H; Zhong, M1
Bertolini, M; Chéret, J; Gherardini, J; Hardman, JA; Mace, K; Paus, R; Uchida, Y1
Ankarali, S; Dagistan, Y; Kilinc, E; Torun, IE1
Coll, RC; Mariani, ML; Penissi, AB; Vargas, PM1
Chang, S; Kim, DH; Kim, HY; Kim, SC; Ryu, Y; Yi, YJ1
Brown, S; Clark, A; Duarte, FCK; Hurtig, M; Simpson, J; Srbely, J1
Guan, M; Wang, Y; Ying, S1
Edvinsson, L; Fulop, F; Lukacs, M; Tajti, J; Toldi, J; Vecsei, L1
Dempsey, ER; Marcoionni, AM; Sorby-Adams, AJ; Turner, RJ; Woenig, JA1
Chen, F; Chen, H; Chen, Z; Dong, R; Fan, L; Gu, D; Lai, K; Lin, Y; Sun, L; Zhang, W1
Ramachandran, R1
Altamirano-Reyna, F; Arreola-Peralta, LD; Galindo-González, DM; Lacivita, E; Leopoldo, M; Solis-Anguiano, JG; Terrón, JA1
Doche, I; Ericson, M; Hordinsky, MK; McAdams, BD; Romiti, R; Valente, NS; Wilcox, GL1
Dong, HJ; Gao, XW; Liu, HY; Wang, SS; Zhang, XM1
Clark, A; Duarte, FCK; Hurtig, M; Simpson, J; Srbely, JZ1
Navratilova, E; Porreca, F1
Fantozzi, R; Rosa, AC1
Ericson, ME; Gupta, K; Gupta, M; Luk, K; Nguyen, J; Simone, DA; Vang, D; Vincent, L1
Leonard, AV; Thornton, E; Vink, R1
Chavarría-Bolaños, D; Flores-Reyes, H; Lombana, N; Martinez-Zumaran, A; Pozos-Guillen, A1
Carlsten, CR; MacNutt, MJ; Sava, F1
Li, PB; Luo, YL; Nie, YC; Su, WW; Wang, S; Zhang, CC; Zhang, KJ; Zheng, YF1
Delgado, L; Moreira, A; Palmares, C; Pirraco, A; Ramalho, R; Soares, R1
Camparis, CM; de Avila, ED; de Godoi Gonçalves, DA; de Molon, RS1
Chadi, G; Ferreira, LM; Freitas, JO; Hochman, B; Lapin, GA; Maximino, JR; Mella, SM; Quieregatto, PR1
Jiao, L; Xiong, J; Zhang, W1
Borbély, É; Helyes, Z; Kemény, Á; Markovics, A; McDougall, JJ; Pintér, E; Quinn, JP; Sándor, K; Szolcsányi, J1
Corrigan, F; Leonard, AV; Mander, KA; Vink, R1
Amadesi, S; Andrè, E; Baraldi, PG; Bunnett, NW; Campi, B; Civelli, M; Creminon, C; Geppetti, P; Massi, D; Materazzi, S; Nassini, R; Patacchini, R; Poole, DP; Trevisani, M; Vaksman, N1
Azuero-Holguín, MM; Caviedes-Bucheli, J; Muñoz, HR; Ulate, E1
Diraman, E; Lütfioğlu, M; Odyakmaz, S; Pamuk, F; Sakallioğlu, EE; Sakallioğlu, U1
Aruna, G; Chowdhry, S; Pradeep, AR; Raj, S1
Birklein, F; He, L; Krämer, HH; Lu, B; Sommer, C1
Irwin, CR; Killough, SA; Lundy, FT1
Bunnett, NW; Cattaruzza, F; Cottrell, GS; Vaksman, N1
Keeble, JE1
Carmichael, NM; Charlton, MP; Dostrovsky, JO1
Barklin, A; Granfeldt, A; Larsson, A; Sloth, E; Theodorsson, E; Tonnesen, E; Tyvold, SS1
Chmielinska, JJ; Kramer, JH; Lu, B; Mak, IT; Spurney, CF; Tejero-Taldo, I; Viswalingham, K; Weglicki, WB1
Ito, K; Miyake, M; Muto, T; Ohshima, M; Sakamoto, T; Takeda, M; Ueda, N1
Fu, YS; Huang, HT; Huang, WH; Liu, SP; Wang, PH1
Boulais, N; Dorange, G; Garcia-Le Gal, C; Gougerot, A; Le Gal, G; Lebonvallet, N; Lefeuvre, L; Misery, L; Pereira, U1
Boulais, N; Gougerot, A; Lebonvallet, N; Lefeuvre, L; Misery, L; Pereira, U1
Azuero-Holguin, MM; Caviedes-Bucheli, J; Gutierrez-Sanchez, L; Higuerey-Bermudez, F; Lombana, N; Munoz, HR; Pereira-Nava, V1
Fang, LP; Li, SJ; Li, ZC; Lin, HJ; Qi, HW; Xie, BM1
Kamijima, M; Miyake, M; Ohshima, M; Sakamoto, T; Takeda, M1
Kamijima, M; Miyake, M; Muto, T; Sakamoto, T; Takeda, M1
Davis, AR; Dickinson, ME; Gannon, FH; Hipp, J; Olmsted-Davis, EA; Rodenberg, E; Salisbury, E; Sonnet, C; Vadakkan, TJ1
Aubdool, AA; Brain, SD1
Arai, Y; Kawata, M; Kida, Y; Kubo, T; Matsuda, K; Morihara, T; Sakamoto, H; Yoshida, A1
Chien, CT; Lee, HM; Li, PC; Wu, CC1
Almeida, J; Beltrão, M; Costa, R; Delgado, L; Guardão, L; Guimarães, JT; Moreira, A; Palmares, C; Pirraco, A; Ramalho, R; Soares, R; Sokhatska, O1
Chen, R; Lai, K; Liu, C; Luo, W; Zhong, N1
Althuber, P; Griesbacher, T; Kerl, H; Legat, FJ; Schicho, R; Schuligoi, R; Wolf, P1
Lafforgue, P; Pham, T1
Cruwys, SC; Hood, VC; Kidd, BL; Seegers, HC; Walsh, DA1
Bowles, WR; Hargreaves, KM; Lepinski, AM; Withrow, JC1
Kramer, JH; Mak, IT; Phillips, TM; Weglicki, WB1
Gjerde, EA; Karlsen, TV; Reed, RK1
Birklein, F; Isselmann, A; Leis, S; Schmelz, M; Weber, M1
Foster, DE; Keith, I; Kweon, CB; Schauer, JJ; Sun, NN; Witten, ML; Wong, SS1
Chiappelli, F; Huang, GT; Lin, LM; Park, SH; Patel, T1
Forsberg, E; Gjerde, EA; Iversen, VV; Karlsen, TV; Kjellén, L; Reed, RK1
Hsu, YY; Jou, YT; Karabucak, B; Kim, S; Simchon, S; Wong, R1
Hsiao, GY; Huang, GT; Park, SH1
Aihara, N; Kanekawa, M; Kasai, K; Kojima, T; Nogimura, A; Yamaguchi, M1
Alaçam, T; Oral, B; Tuncer, LI1
Brodin, E; Gustafsson, H; Olgart, L; Stiller, CO; Taylor, BK; Warsame Afrah, A1
Liddle, RA; Nathan, JD1
Arck, PC; Klapp, BF; Kuhlmei, A; Müller-Röver, S; Peters, EM; Tobin, DJ1
Nies, M; Ro, JY; Zhang, Y1
Abe, T; Arisaka, O; Morimoto, H; Ohori, M; Yamada, Y; Yoshihara, S1
Bhatia, M; Hegde, A1
Jou, YT; Karabucak, B; Kim, S; Simchon, S; Walsch, H1
Cochran, MA; Fugaro, JO; Fugaro, OJ; Gregory, RL; Matis, B; Mjör, I1
Hou, RC; Jeng, KC; Liao, BC; Wang, JS1
Elekes, K; Helyes, Z; Németh, J; Pintér, E; Pozsgai, G; Reglödi, D; Szabó, A; Szolcsányi, J1
Feng, JT; Hu, CP; Lin, MJ; Luo, BL; Tang, YL; Zhu, JQ1
Chang, LW; Chen, SC; Tsai, MH; Wang, HJ; Yu, HS1
Fujimura, K; Kaneyama, K; Kitagawa, Y; Sato, J; Segami, N; Yoshimura, H; Yoshitake, Y1
Cahill, CM; Henry, JL; Landau, AM; Ribeiro-da-Silva, A; St Louis, M; Yashpal, K1
Liddle, RA1
Finke, B; Gierer, P; Gradl, G; Mittlmeier, T; Schattner, S; Vollmar, B1
Arck, PC; Daniltchenko, M; Hagen, E; Hunt, SP; Klapp, BF; Pavlovic, S; Peters, EM; Tobin, DJ1
Fang, L; Li, D; Lin, Q; Xu, X; Zou, X1
Bagoly, T; Börzsei, R; Elekes, K; Helyes, Z; Pintér, E; Pozsgai, G; Szolcsányi, J1
Turner, R; Vink, R1
Avellán, NL; Forster, C; Kemppainen, P; Sorsa, T; Tervahartiala, T1
Hu, CL; Hu, FF; Xiang, JZ1
Messina, P; Ruggeri, A; Scardina, GA1
Rees, H; Sluka, KA; Urban, L; Walpole, CJ; Willis, WD1
Brain, SD; Towler, PK1
Averbeck, B; Guthmann, C; Kress, M; Reeh, PW1
Castellote, JM; Kingery, WS; Maze, M1
Gabaldón, M; Marqués, A1
Calixto, JB; Fröde-Saleh, TS; Medeiros, YS1
Alexacos, N; Letourneau, R; Pang, X; Singh, LK; Theoharides, TC1
Yonehara, N; Yoshimura, M2
Khalil, Z; Modig, M; Nyberg, F; Sanderson, K1
Germonpré, PR; Joos, GF; Pauwels, RA1
Lamey, PJ; Linden, GJ; Lundy, FT; Salmon, AL; Shaw, C1
Burden, DJ; Lamey, PJ; Linden, GJ; Lundy, FT; Mullally, BH; Shaw, C1
Amann, R; Egger, T; Schuligoi, R1
Hilliges, M; Klede, M; Sauerstein, K; Schmelz, M1
Hu, C; Jiang, X; King, KA; Piedimonte, G; Rodriguez, MM; Romaguera, R1
Berggreen, E; Haug, SR; Heyeraas, KJ1
Hide, M; Koro, O; Nimi, N; Okabe, T; Yamamoto, S1
McVey, DC; Vigna, SR1
Henry, CH; Wolford, LM1
Iijima, T; Kabashima, H; Maeda, K; Nagata, K1
Bolyard, LA; Southall, MD; Vasko, MR1
Boissonade, FM; Rodd, HD1

Reviews

15 review(s) available for substance p and Neurogenic Inflammation

ArticleYear
Molecular Mechanisms of Neurogenic Inflammation of the Skin.
    International journal of molecular sciences, 2023, Mar-05, Volume: 24, Issue:5

    Topics: Endothelial Cells; Humans; Neurogenic Inflammation; Neuropeptides; Skin; Substance P

2023
Migraine, Neurogenic Inflammation, Drug Development - Pharmacochemical Aspects.
    Current medicinal chemistry, 2017, Volume: 24, Issue:33

    Topics: Animals; Calcitonin Gene-Related Peptide; Drug Discovery; Humans; Kynurenic Acid; Migraine Disorders; Molecular Targeted Therapy; Neurogenic Inflammation; Pituitary Adenylate Cyclase-Activating Polypeptide; Substance P; Vasoactive Intestinal Peptide

2017
The Role of Neurogenic Inflammation in Blood-Brain Barrier Disruption and Development of Cerebral Oedema Following Acute Central Nervous System (CNS) Injury.
    International journal of molecular sciences, 2017, Aug-17, Volume: 18, Issue:8

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries, Traumatic; Calcitonin Gene-Related Peptide; Capillary Permeability; Gene Expression Regulation; Humans; Neurogenic Inflammation; Neurons; Substance P

2017
Neurogenic inflammation and its role in migraine.
    Seminars in immunopathology, 2018, Volume: 40, Issue:3

    Topics: Calcitonin Gene-Related Peptide; Humans; Migraine Disorders; Neurogenic Inflammation; Neurons; Substance P

2018
The role of histamine in neurogenic inflammation.
    British journal of pharmacology, 2013, Volume: 170, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Histamine; Histamine Release; Humans; Mast Cells; Neurogenic Inflammation; Neurons; Nociceptive Pain; Substance P

2013
Relationship between levels of neuropeptide Substance P in periodontal disease and chronic pain: a literature review.
    Journal of investigative and clinical dentistry, 2014, Volume: 5, Issue:2

    Topics: Alveolar Bone Loss; Chronic Pain; Gingival Crevicular Fluid; Humans; Neurogenic Inflammation; Periodontitis; Substance P

2014
Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation.
    Journal of neuroinflammation, 2016, 10-11, Volume: 13, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain Injuries, Traumatic; Humans; Inflammation; Neurogenic Inflammation; Neuroglia; Neurons; Substance P; Transient Receptor Potential Channels

2016
Neuropeptides in dental pulp: the silent protagonists.
    Journal of endodontics, 2008, Volume: 34, Issue:7

    Topics: Alveolar Bone Loss; Animals; Calcitonin Gene-Related Peptide; Dental Pulp; Humans; Neurogenic Inflammation; Neurokinin A; Neurons, Afferent; Neuropeptide Y; Neuropeptides; Pulpitis; Substance P; Toothache; Vasoactive Intestinal Peptide

2008
Neurovascular aspects of skin neurogenic inflammation.
    The journal of investigative dermatology. Symposium proceedings, 2011, Volume: 15, Issue:1

    Topics: Animals; Ankyrins; Calcitonin Gene-Related Peptide; Dermatitis; Dogs; Female; Haplorhini; Humans; Male; Mice; Neurogenic Inflammation; Pain; Peptide Hydrolases; Rats; Rosacea; Sex Factors; Skin; Substance P; TRPV Cation Channels

2011
Reflex sympathetic dystrophy syndrome and neuromediators.
    Joint bone spine, 2003, Volume: 70, Issue:1

    Topics: Calcitonin Gene-Related Peptide; Humans; Neurogenic Inflammation; Neuropeptide Y; Neuropeptides; Pain; Reflex Sympathetic Dystrophy; Substance P; Sympathetic Nervous System; Syndrome

2003
Neurogenic inflammation and pancreatitis.
    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2004, Volume: 4, Issue:6

    Topics: Bradykinin; Humans; Ion Channels; Neurogenic Inflammation; Neurons, Afferent; Pancreatitis; Receptors, Drug; Substance P; TRPV Cation Channels

2004
The role of Transient Receptor Potential Vanilloid 1 (TRPV1) channels in pancreatitis.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:8

    Topics: Abdominal Pain; Acute Disease; Animals; Humans; Models, Biological; Neurogenic Inflammation; Neuropeptides; Pancreas; Pancreatitis; Substance P; Transient Receptor Potential Channels; TRPV Cation Channels

2007
Inhibition of neurogenic inflammation as a novel treatment for ischemic stroke.
    Timely topics in medicine. Cardiovascular diseases, 2007, Oct-01, Volume: 11

    Topics: Animals; Brain Edema; Brain Injuries; Humans; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Stroke; Substance P

2007
[Neurologic inflammation and oral disease. An aetiopathogenic hypothesis].
    Recenti progressi in medicina, 2007, Volume: 98, Issue:12

    Topics: Animals; Disease Models, Animal; Disease Progression; Humans; Microcirculation; Mouth Diseases; Mouth Mucosa; Neurogenic Inflammation; Neuropeptides; Nociceptors; Pain; Rats; Substance P; Swine; Tongue; Vasoactive Intestinal Peptide

2007
Role of tachykinins in asthma.
    Allergy, 2000, Volume: 55, Issue:4

    Topics: Asthma; Humans; Lung; Neurogenic Inflammation; Neurokinin A; Neurons, Afferent; Receptors, Tachykinin; Substance P

2000

Trials

4 trial(s) available for substance p and Neurogenic Inflammation

ArticleYear
Expression of substance P, calcitonin gene-related peptide, β-endorphin and methionine-enkephalin in human dental pulp tissue after orthodontic intrusion: a pilot study.
    The Angle orthodontist, 2014, Volume: 84, Issue:3

    Topics: Adolescent; beta-Endorphin; Bicuspid; Calcitonin Gene-Related Peptide; Child; Dental Pulp; Enkephalin, Methionine; Female; Humans; Male; Neurogenic Inflammation; Neurotransmitter Agents; Opioid Peptides; Pain; Pilot Projects; Substance P; Tooth Movement Techniques

2014
Nasal neurogenic inflammation markers increase after diesel exhaust inhalation in individuals with asthma.
    American journal of respiratory and critical care medicine, 2013, Sep-15, Volume: 188, Issue:6

    Topics: Adult; Analysis of Variance; Asthma; Biomarkers; Calcitonin Gene-Related Peptide; Cross-Over Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inhalation; Male; Middle Aged; Nasal Cavity; Nasal Lavage Fluid; Neurogenic Inflammation; Substance P; Vehicle Emissions; Young Adult

2013
The effect of three different rotary instrumentation systems on substance P and calcitonin gene-related peptide expression in human periodontal ligament.
    Journal of endodontics, 2010, Volume: 36, Issue:12

    Topics: Adolescent; Adult; Bicuspid; Calcitonin Gene-Related Peptide; Dental Instruments; Endpoint Determination; Humans; Neurogenic Inflammation; Periapical Periodontitis; Periodontal Ligament; Root Canal Preparation; Statistics, Nonparametric; Substance P; Tooth Extraction; Young Adult

2010
Substance-P-induced protein extravasation is bilaterally increased in complex regional pain syndrome.
    Experimental neurology, 2003, Volume: 183, Issue:1

    Topics: Adult; Arm; Blood Proteins; Complex Regional Pain Syndromes; Female; Humans; Injections, Intradermal; Leg; Male; Microdialysis; Middle Aged; Neurogenic Inflammation; Reference Values; Regional Blood Flow; Skin; Substance P; Vasodilation

2003

Other Studies

98 other study(ies) available for substance p and Neurogenic Inflammation

ArticleYear
Pentobarbital may protect against neurogenic inflammation after surgery via inhibition of substance P release from peripheral nerves of rats.
    Neuroscience letters, 2022, 02-06, Volume: 771

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Calcium Channels; Capsaicin; Cells, Cultured; Ganglia, Spinal; Ketamine; Male; Neurogenic Inflammation; Pentobarbital; Peripheral Nerves; Rats; Rats, Wistar; Sensory System Agents; Substance P; TRPV Cation Channels

2022
Endogenous Inflammatory Mediators Produced by Injury Activate TRPV1 and TRPA1 Nociceptors to Induce Sexually Dimorphic Cold Pain That Is Dependent on TRPM8 and GFRα3.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023, 04-12, Volume: 43, Issue:15

    Topics: Animals; Calcitonin Gene-Related Peptide; Cold Temperature; Female; Glial Cell Line-Derived Neurotrophic Factor; Hyperalgesia; Male; Mice; Neurogenic Inflammation; Nociceptors; Pain; Sensory Receptor Cells; Substance P; Toll-Like Receptor 4; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2023
C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation.
    Nature, 2023, Volume: 622, Issue:7983

    Topics: Animals; Bacterial Toxins; Calcitonin Gene-Related Peptide; Cecum; Clostridioides difficile; Clostridium Infections; Inflammation Mediators; Mice; Neurogenic Inflammation; Neurons, Afferent; Pericytes; Receptors, Neurokinin-1; Signal Transduction; Substance P

2023
Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion.
    European journal of pharmacology, 2023, Nov-15, Volume: 959

    Topics: Animals; Cough; Gabapentin; Gastroesophageal Reflux; Guinea Pigs; Hydrochloric Acid; Lung; Neurogenic Inflammation; Perfusion; Receptors, Neurokinin-1; Substance P

2023
Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Adult; Antigens, CD; Antigens, CD34; Antigens, Differentiation, Myelomonocytic; Apoptosis; Cell Differentiation; Female; Humans; Macrophages; Neurogenic Inflammation; Organ Culture Techniques; Skin; Stem Cells; Substance P

2020
Receptor mechanisms mediating the anti-neuroinflammatory effects of endocannabinoid system modulation in a rat model of migraine.
    The European journal of neuroscience, 2022, Volume: 55, Issue:4

    Topics: Animals; Calcitonin Gene-Related Peptide; Endocannabinoids; Male; Migraine Disorders; Neurogenic Inflammation; Nitroglycerin; Rats; Rimonabant; Substance P

2022
Natural α,β-unsaturated lactones inhibit neuropeptide-induced mast cell activation in an in vitro model of neurogenic inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2020, Volume: 69, Issue:10

    Topics: Animals; Cells, Cultured; Lactones; Mast Cells; Neurogenic Inflammation; Neurotensin; Peptide Fragments; Rats, Wistar; Serotonin; Substance P

2020
Electroacupuncture at Neurogenic Spots in Referred Pain Areas Attenuates Hepatic Damages in Bile Duct-Ligated Rats.
    International journal of molecular sciences, 2021, Feb-17, Volume: 22, Issue:4

    Topics: Animals; Bile Ducts; Calcitonin Gene-Related Peptide; Electric Conductivity; Electroacupuncture; Hyperalgesia; Ligation; Liver; Neurogenic Inflammation; Pain, Referred; Rats, Sprague-Dawley; Skin; Substance P

2021
Experimentally induced spine osteoarthritis in rats leads to neurogenic inflammation within neurosegmentally linked myotomes.
    Experimental gerontology, 2021, 07-01, Volume: 149

    Topics: Animals; Calcitonin Gene-Related Peptide; Hyperalgesia; Neurogenic Inflammation; Osteoarthritis, Spine; Rats; Rats, Sprague-Dawley; Substance P

2021
Increased expression of transient receptor potential channels and neurogenic factors associates with cough severity in a guinea pig model.
    BMC pulmonary medicine, 2021, Jun-02, Volume: 21, Issue:1

    Topics: Animals; Bleomycin; Cough; Disease Models, Animal; Disease Progression; Guinea Pigs; Idiopathic Pulmonary Fibrosis; Lung; Male; Neurogenic Inflammation; Substance P; TRPA1 Cation Channel; TRPV Cation Channels

2021
Vagotomy decreases the neuronal activities of medulla oblongata and alleviates neurogenic inflammation of airways induced by repeated intra-esophageal instillation of HCl in guinea pigs.
    Physiological research, 2017, 12-20, Volume: 66, Issue:6

    Topics: Animals; Capillary Permeability; Esophagus; Guinea Pigs; Hydrochloric Acid; Lung; Male; Medulla Oblongata; Neurogenic Inflammation; Pneumonia, Aspiration; Proto-Oncogene Proteins c-fos; Reflex, Abnormal; Substance P; Vagotomy

2017
Potentiation of capsaicin-induced neurogenic inflammation by 5-HT7 receptors in the rat hind paw: Involvement of calcitonin gen-related peptide.
    Peptides, 2018, Volume: 105

    Topics: Animals; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Foot; Humans; Male; Neurogenic Inflammation; Neurons, Afferent; Phenols; Rats; Receptors, Calcitonin Gene-Related Peptide; Receptors, Serotonin; Substance P; Sulfonamides

2018
Evidence for neurogenic inflammation in lichen planopilaris and frontal fibrosing alopecia pathogenic mechanism.
    Experimental dermatology, 2020, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Biopsy; Calcitonin Gene-Related Peptide; Chronic Disease; Epidermis; Female; Humans; Immunohistochemistry; Inflammation; Lichen Planus; Lipid Metabolism; Lymphocytes; Male; Microscopy, Confocal; Middle Aged; Neurogenic Inflammation; Neuropeptides; Scalp; Scalp Dermatoses; Substance P

2020
Mechanism of interaction between ocular and nasal neurogenic inflammation in allergic rhinoconjunctivitis.
    International ophthalmology, 2019, Volume: 39, Issue:10

    Topics: Animals; Biomarkers; Conjunctiva; Conjunctivitis, Allergic; Nasal Mucosa; Nerve Growth Factor; Neurogenic Inflammation; Rats; Substance P; Vasoactive Intestinal Peptide

2019
Association between naturally occurring spine osteoarthritis in geriatric rats and neurogenic inflammation within neurosegmentally linked skeletal muscle.
    Experimental gerontology, 2019, Volume: 118

    Topics: Animals; Male; Muscle, Skeletal; Neurogenic Inflammation; Osteoarthritis, Spine; Rats; Rats, Inbred WKY; Receptor, PAR-2; Substance P; X-Ray Microtomography

2019
Substance P and Inflammatory Pain: Getting It Wrong and Right Simultaneously.
    Neuron, 2019, 02-06, Volume: 101, Issue:3

    Topics: Humans; Mast Cells; Nerve Tissue Proteins; Neurogenic Inflammation; Pain; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Substance P

2019
Mast cell activation contributes to sickle cell pathobiology and pain in mice.
    Blood, 2013, Sep-12, Volume: 122, Issue:11

    Topics: Anemia, Sickle Cell; Animals; Benzamides; Cells, Cultured; Cytokines; Ganglia, Spinal; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hyperalgesia; Hypoxia; Imatinib Mesylate; Leukocyte Count; Mast Cells; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Neurogenic Inflammation; Nociceptors; Pain; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Skin; Substance P

2013
Substance P as a mediator of neurogenic inflammation after balloon compression induced spinal cord injury.
    Journal of neurotrauma, 2013, Nov-01, Volume: 30, Issue:21

    Topics: Animals; Aquaporin 4; Capillary Permeability; Cerebrospinal Fluid Pressure; Disease Models, Animal; Edema; Neurogenic Inflammation; Rabbits; Recovery of Function; Spinal Cord Injuries; Substance P

2013
Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:12

    Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Female; Flavanones; Guinea Pigs; Lung; Male; Neprilysin; Neurogenic Inflammation; Nicotiana; Propylene Glycols; Receptors, Neurokinin-1; Smoke; Substance P; Thiazolidines

2013
Neurogenic inflammation in the airways of elite swimmers.
    The Journal of sports medicine and physical fitness, 2014, Volume: 54, Issue:2

    Topics: Adult; Asthma, Exercise-Induced; Case-Control Studies; Cross-Sectional Studies; Female; Humans; Male; Neurogenic Inflammation; Respiratory Function Tests; Sputum; Substance P; Swimming

2014
Does dexamethasone act in neuropeptides SP and CGRP in neurogenic inflammation of the skin? An experimental study.
    Acta cirurgica brasileira, 2015, Volume: 30, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Calcitonin Gene-Related Peptide; Dermatitis; Dexamethasone; Injections, Subcutaneous; Male; Neurogenic Inflammation; Random Allocation; Rats, Wistar; Substance P; Time Factors; Wound Healing

2015
[Effects of Suspending Moxibustion at "Dazhui" (GV 14) on Neurogenic Inflammation in Asthma Rats].
    Zhen ci yan jiu = Acupuncture research, 2015, Volume: 40, Issue:5

    Topics: Acupuncture Points; Animals; Asthma; Bronchoalveolar Lavage Fluid; Humans; Male; Moxibustion; Nerve Growth Factor; Neurogenic Inflammation; Neurokinin A; Rats; Rats, Sprague-Dawley; Substance P

2015
Role of capsaicin-sensitive nerves and tachykinins in mast cell tryptase-induced inflammation of murine knees.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2016, Volume: 65, Issue:9

    Topics: Animals; Arthritis; Calcitonin Gene-Related Peptide; Capsaicin; Cytokines; Edema; Hyperalgesia; Knee Joint; Male; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Pain; Protein Precursors; Receptor, PAR-2; Receptors, Neurokinin-1; Substance P; Tachykinins; Touch; TRPV Cation Channels; Tryptases

2016
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:7

    Topics: Acrolein; Aldehydes; Animals; Ankyrins; Calcitonin Gene-Related Peptide; Calcium Channels; Calcium Signaling; Cell Line; Ganglia, Spinal; Guinea Pigs; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; Neurons, Afferent; Nicotiana; Rats; Smoke; Substance P; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels

2008
Local peptidergic innervation of gingiva in smoking and non-smoking periodontitis patients.
    Journal of periodontology, 2008, Volume: 79, Issue:8

    Topics: Adult; Alveolar Bone Loss; Biopsy; Calcitonin Gene-Related Peptide; Chronic Disease; Dental Plaque Index; Female; Gingiva; Gingival Hemorrhage; Humans; Inflammation Mediators; Male; Middle Aged; Neurogenic Inflammation; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Smoking; Substance P

2008
Gingival crevicular fluid and plasma levels of neuropeptide Substance-P in periodontal health, disease and after nonsurgical therapy.
    Journal of periodontal research, 2009, Volume: 44, Issue:2

    Topics: Adult; Aged; Alveolar Bone Loss; Case-Control Studies; Chronic Periodontitis; Dental Scaling; Female; Gingival Crevicular Fluid; Gingivitis; Humans; Male; Middle Aged; Neurogenic Inflammation; Periodontal Index; Statistics, Nonparametric; Substance P

2009
Increased pain and neurogenic inflammation in mice deficient of neutral endopeptidase.
    Neurobiology of disease, 2009, Volume: 35, Issue:2

    Topics: Animals; Cold Temperature; Edema; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Hindlimb; Hot Temperature; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Neprilysin; Neurogenic Inflammation; Pain; Pain Measurement; Physical Stimulation; Sciatic Nerve; Skin; Skin Temperature; Substance P

2009
Substance P expression by human dental pulp fibroblasts: a potential role in neurogenic inflammation.
    Journal of endodontics, 2009, Volume: 35, Issue:1

    Topics: Blotting, Western; Cells, Cultured; Dental Caries; Dental Pulp; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1beta; Neurogenic Inflammation; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; Substance P; Transforming Growth Factor beta1

2009
Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation.
    British journal of pharmacology, 2009, Volume: 156, Issue:5

    Topics: Animals; Aspartic Acid Endopeptidases; Calcium; Calcium Signaling; Capillary Permeability; Cell Line; Ear; Endocytosis; Endosomes; Endothelial Cells; Endothelin-Converting Enzymes; Endothelium, Vascular; Humans; Male; Metalloendopeptidases; Microvessels; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Skin; Substance P; Urinary Bladder

2009
Re-sensitization of neuropeptide receptors: should we stop the recycling?
    British journal of pharmacology, 2009, Volume: 156, Issue:5

    Topics: Animals; Aspartic Acid Endopeptidases; Calcium Signaling; Capillary Permeability; Endocytosis; Endosomes; Endothelial Cells; Endothelin-Converting Enzymes; Endothelium, Vascular; Metalloendopeptidases; Microvessels; Neurogenic Inflammation; Rats; Receptors, Neurokinin-1; Substance P

2009
Sex differences in inflammation evoked by noxious chemical, heat and electrical stimulation.
    Brain research, 2009, Jun-18, Volume: 1276

    Topics: Analysis of Variance; Animals; Capsaicin; Electric Stimulation; Estrous Cycle; Evans Blue; Female; Foot; Hindlimb; Hot Temperature; Male; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; Sex Characteristics; Skin; Substance P; Time Factors

2009
Alteration of neuropeptides in the lung tissue correlates brain death-induced neurogenic edema.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:7

    Topics: Animals; Biomarkers; Brain Death; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Disease Models, Animal; Female; Lung; Neurogenic Inflammation; Neuropeptide Y; Neuropeptides; Predictive Value of Tests; Pulmonary Edema; Substance P; Swine; Vasoconstriction; Vasodilation

2009
Neutral endopeptidase inhibition enhances substance P mediated inflammation due to hypomagnesemia.
    Magnesium research, 2009, Volume: 22, Issue:3

    Topics: Animals; Glycopeptides; Heart; Immunohistochemistry; Intestines; Magnesium Deficiency; Neprilysin; Neurogenic Inflammation; Protease Inhibitors; Rats; Substance P; Up-Regulation

2009
Development of mechanisms associated with neurogenic-mediated skin inflammation during the growth of rats.
    Pediatric research, 2010, Volume: 67, Issue:4

    Topics: Age Factors; Animals; Capsaicin; Cell Degranulation; Female; Fixatives; Formaldehyde; Male; Mast Cells; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Neurokinin-1; Sensory System Agents; Skin; Substance P

2010
Warm SPA-induced hyperthermia confers protection to rats against airway inflammation evoked by capsaicin and substance P.
    Autonomic neuroscience : basic & clinical, 2010, Jun-24, Volume: 155, Issue:1-2

    Topics: Animals; Blotting, Western; Capillary Permeability; Capsaicin; HSP72 Heat-Shock Proteins; Hyperthermia, Induced; Hypotension; Male; Medicine, Traditional; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; Respiratory System; Sensory System Agents; Substance P; Trachea

2010
Effects of sangre de drago in an in vitro model of cutaneous neurogenic inflammation.
    Experimental dermatology, 2010, Volume: 19, Issue:9

    Topics: Animals; Capsaicin; Cells, Cultured; Coculture Techniques; Croton; Dermatitis; Drug Evaluation, Preclinical; Immunoenzyme Techniques; Keratinocytes; Male; Neurogenic Inflammation; Phytotherapy; Plant Extracts; Sensory Receptor Cells; Sensory System Agents; Substance P; Swine; Tetrazolium Salts; Thiazoles; Toxicity Tests

2010
Development of an in vitro coculture of primary sensitive pig neurons and keratinocytes for the study of cutaneous neurogenic inflammation.
    Experimental dermatology, 2010, Volume: 19, Issue:10

    Topics: Animals; Cells, Cultured; Coculture Techniques; Keratinocytes; Laminaria; Male; Neurogenic Inflammation; Plant Extracts; Sensory Receptor Cells; Skin; Substance P; Sus scrofa; Vernonia

2010
[To explore the mechanisms of neurogenic inflammation and airway hyperresponsiveness of rat by inhaled sulfur].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2009, Volume: 25, Issue:1

    Topics: Air Pollutants; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Bronchitis; Bronchoalveolar Lavage Fluid; Male; Nerve Fibers; Neurogenic Inflammation; Random Allocation; Rats; Rats, Sprague-Dawley; Substance P; Sulfur Dioxide

2009
Staphylococcal enterotoxin B causes proliferation of sensory C-fibers and subsequent enhancement of neurogenic inflammation in rat skin.
    The Journal of infectious diseases, 2011, Mar-15, Volume: 203, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Brain-Derived Neurotrophic Factor; Capillary Permeability; Disease Models, Animal; Enterotoxins; Fluocinonide; Fluorescent Antibody Technique; Immunosuppressive Agents; Male; Nerve Fibers, Unmyelinated; Nerve Growth Factor; Neurogenic Inflammation; Rats; Receptors, Neurokinin-1; Skin; Specific Pathogen-Free Organisms; Substance P; Tacrolimus; TRPV Cation Channels; Tumor Necrosis Factor-alpha

2011
Proliferation of sensory C-fibers and subsequent neurogenic inflammation in rat airway induced by inhaled lipopolysaccharide.
    Neurotoxicology, 2011, Volume: 32, Issue:6

    Topics: Administration, Inhalation; Aerosols; Age Factors; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Capillary Permeability; Cell Proliferation; Disease Models, Animal; Immunohistochemistry; Infliximab; Lipopolysaccharides; Male; Nerve Fibers, Unmyelinated; Nerve Growth Factor; Neurogenic Inflammation; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P; Time Factors; Trachea; Tumor Necrosis Factor-alpha

2011
Sensory nerve induced inflammation contributes to heterotopic ossification.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:10

    Topics: Animals; Bone Morphogenetic Protein 2; Calcitonin Gene-Related Peptide; Cell Line; Cromolyn Sodium; Immunohistochemistry; Kruppel-Like Factor 4; Mice; Mice, Inbred C57BL; Neurogenic Inflammation; Ossification, Heterotopic; Sensory Receptor Cells; Substance P; TRPV Cation Channels; X-Ray Microtomography

2011
Immunohistochemical analysis of the effects of estrogen on intraarticular neurogenic inflammation in a rat anterior cruciate ligament transection model of osteoarthritis.
    Connective tissue research, 2012, Volume: 53, Issue:3

    Topics: Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Biomarkers; Calcitonin Gene-Related Peptide; Disease Models, Animal; Estradiol; Estrogens; Female; Immunohistochemistry; Neurogenic Inflammation; Osteoarthritis, Knee; Ovariectomy; Rats; Rats, Wistar; Stifle; Substance P; Synovial Membrane; Ubiquitin Thiolesterase

2012
Inhibitory effect of botulinum toxin type A on the NANC system in rat respiratory models of neurogenic inflammation.
    Archives of biochemistry and biophysics, 2012, Aug-15, Volume: 524, Issue:2

    Topics: Animals; Arterial Occlusive Diseases; Botulinum Toxins, Type A; Brain Stem; Capsaicin; Disease Models, Animal; Lung; Male; Neurogenic Inflammation; Neurotransmitter Agents; Pneumonia; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Substance P; Synaptosomal-Associated Protein 25

2012
Neurogenic inflammation in allergen-challenged obese mice: A missing link in the obesity-asthma association?
    Experimental lung research, 2012, Volume: 38, Issue:6

    Topics: Allergens; Animals; Asthma; Blood Glucose; Bronchoalveolar Lavage Fluid; Cell Count; Diet, High-Fat; Immunoglobulin E; Insulin; Lung; Mice; Mice, Inbred BALB C; Mice, Obese; Neurogenic Inflammation; Obesity; Ovalbumin; Substance P; Tachykinins

2012
Neurogenic airway inflammation induced by repeated intra-esophageal instillation of HCl in guinea pigs.
    Inflammation, 2013, Volume: 36, Issue:2

    Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Calcitonin Gene-Related Peptide; Esophagus; Guinea Pigs; Hydrochloric Acid; Lung; Neurogenic Inflammation; Neurokinin A; Neurokinin B; Neuropeptides; Nodose Ganglion; Pneumonia; Respiratory System; Substance P; Trachea

2013
Repeated subinflammatory ultraviolet B irradiation increases substance P and calcitonin gene-related peptide content and augments mustard oil-induced neurogenic inflammation in the skin of rats.
    Neuroscience letters, 2002, Sep-06, Volume: 329, Issue:3

    Topics: Animals; Calcitonin Gene-Related Peptide; Female; Mustard Plant; Nerve Fibers; Neurogenic Inflammation; Neurons, Afferent; Plant Extracts; Plant Oils; Rats; Rats, Sprague-Dawley; Skin; Substance P; Ultraviolet Rays

2002
Enhancement of angiogenesis by endogenous substance P release and neurokinin-1 receptors during neurogenic inflammation.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:1

    Topics: Animals; Endothelium; Knee Joint; Macrophages; Male; Neovascularization, Pathologic; Neurogenic Inflammation; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Receptors, Neurokinin-1; Substance P

2003
Tissue levels of immunoreactive substance P are increased in patients with irreversible pulpitis.
    Journal of endodontics, 2003, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Dental Pulp; Humans; Microdialysis; Middle Aged; Neurogenic Inflammation; Pulpitis; Radioimmunoassay; Substance P; Toothache

2003
Dietary magnesium intake influences circulating pro-inflammatory neuropeptide levels and loss of myocardial tolerance to postischemic stress.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:6

    Topics: Animals; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Glutathione; Hemodynamics; Magnesium; Magnesium Deficiency; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Neurogenic Inflammation; Oxidative Stress; Rats; Rats, Sprague-Dawley; Spin Trapping; Substance P

2003
Lowering of interstitial fluid pressure in rat trachea after substance P alone and in combination with calcitonin gene-related peptide.
    Acta physiologica Scandinavica, 2003, Volume: 178, Issue:2

    Topics: Animals; Calcitonin Gene-Related Peptide; Extracellular Space; Female; Hydrostatic Pressure; Neurogenic Inflammation; Rats; Rats, Wistar; Substance P; Trachea

2003
Tachykinin substance P signaling involved in diesel exhaust-induced bronchopulmonary neurogenic inflammation in rats.
    Archives of toxicology, 2003, Volume: 77, Issue:11

    Topics: Animals; Bronchitis; Capsaicin; Endopeptidases; Female; Immunoenzyme Techniques; Immunohistochemistry; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Neurons, Afferent; Particle Size; Pneumonia; Radiopharmaceuticals; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Substance P; Technetium Tc 99m Aggregated Albumin; Vehicle Emissions

2003
Substance P induces interleukin-8 secretion from human dental pulp cells.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2003, Volume: 96, Issue:4

    Topics: Adolescent; Adult; Analysis of Variance; Calcitonin Gene-Related Peptide; Cells, Cultured; Dental Pulp; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Interleukin-8; Neurogenic Inflammation; Stimulation, Chemical; Substance P; Time Factors

2003
Neurogenic inflammation in mice deficient in heparin-synthesizing enzyme.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:3

    Topics: Acute Disease; Amidohydrolases; Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Capsaicin; Extracellular Fluid; Female; Heparin; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenic Inflammation; p-Methoxy-N-methylphenethylamine; Skin; Substance P; Sulfotransferases

2004
Effect of nitric oxide synthase inhibitor (L-NAME) on substance P-induced vasodilatation in the dental pulp.
    International endodontic journal, 2003, Volume: 36, Issue:12

    Topics: Animals; Calcitonin Gene-Related Peptide; Cats; Dental Pulp; Endothelium, Vascular; Enzyme Inhibitors; Female; Male; Neurogenic Inflammation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Papaverine; Regional Blood Flow; Substance P; Vasodilation; Vasodilator Agents

2003
Role of substance P and calcitonin gene-related peptide in the regulation of interleukin-8 and monocyte chemotactic protein-1 expression in human dental pulp.
    International endodontic journal, 2004, Volume: 37, Issue:3

    Topics: Calcitonin Gene-Related Peptide; Cells, Cultured; Chemokine CCL2; Culture Techniques; Dental Pulp; Humans; Interleukin-8; Neurogenic Inflammation; Pulpitis; Substance P

2004
Neuropeptides stimulate production of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha in human dental pulp cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:5

    Topics: Calcitonin Gene-Related Peptide; Cells, Cultured; Dental Pulp; Female; Fibroblasts; Humans; Interleukin-1; Interleukin-6; Male; Neurogenic Inflammation; Substance P; Tooth Movement Techniques; Tumor Necrosis Factor-alpha

2004
Substance P expression is elevated in inflamed human periradicular tissue.
    Journal of endodontics, 2004, Volume: 30, Issue:5

    Topics: Acute Disease; Chronic Disease; Humans; Neurogenic Inflammation; Neutrophils; Periapical Granuloma; Substance P

2004
Capsaicin-evoked substance P release in rat dorsal horn increases after peripheral inflammation: a microdialysis study.
    Neuroscience letters, 2004, Sep-23, Volume: 368, Issue:2

    Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Freund's Adjuvant; Male; Microdialysis; Neurogenic Inflammation; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Time Factors; Valine

2004
Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin.
    Brain, behavior, and immunity, 2005, Volume: 19, Issue:3

    Topics: Animals; Apoptosis; Cell Degranulation; Female; Fluorescent Antibody Technique; GAP-43 Protein; Mast Cells; Mice; Mice, Inbred C57BL; Nerve Fibers; Neurogenic Inflammation; Neuroimmunomodulation; Neuronal Plasticity; Skin; Stress, Psychological; Substance P

2005
Substance P does not play a critical role in neurogenic inflammation in the rat masseter muscle.
    Brain research, 2005, Jun-14, Volume: 1047, Issue:1

    Topics: Analgesics; Animals; Capsaicin; Disease Models, Animal; Edema; Inflammation Mediators; Male; Masseter Muscle; Mustard Plant; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Plant Extracts; Plant Oils; Pyrrolidonecarboxylic Acid; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Substance P

2005
Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.
    International archives of allergy and immunology, 2005, Volume: 138, Issue:1

    Topics: Amides; Animals; Arachidonic Acids; Bronchi; Bronchoconstriction; Calcium Channel Blockers; Camphanes; Cannabinoid Receptor Agonists; Capsaicin; Electric Stimulation; Endocannabinoids; Ethanolamines; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Organ Culture Techniques; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Substance P

2005
Neurogenic inflammation in acute pancreatitis.
    JOP : Journal of the pancreas, 2005, Sep-10, Volume: 6, Issue:5

    Topics: Acute Disease; Humans; Neurogenic Inflammation; Pancreatitis; Receptors, Neurokinin-1; Substance P

2005
The role of endothelial nitric oxide in the Substance P induced vasodilation in bovine dental pulp.
    Journal of endodontics, 2005, Volume: 31, Issue:10

    Topics: Analysis of Variance; Animals; Cattle; Dental Pulp; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Muscle, Smooth, Vascular; Neurogenic Inflammation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Pulpitis; Substance P; Vasodilation; Vasodilator Agents

2005
The dental pulp: inflammatory markers and vital bleaching.
    American journal of dentistry, 2005, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Biomarkers; Calcitonin Gene-Related Peptide; Carbamide Peroxide; Child; Dental Pulp; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Neurogenic Inflammation; Oxidants; Peroxides; Substance P; Tooth Bleaching; Urea

2005
Enhancement of the release of inflammatory mediators by substance P in rat basophilic leukemia RBL-2H3 cells.
    Journal of biomedical science, 2006, Volume: 13, Issue:5

    Topics: Animals; Anti-Allergic Agents; Cell Line; Ginsenosides; Inflammation Mediators; MAP Kinase Signaling System; Neurogenic Inflammation; Rats; Serum Albumin, Bovine; Signal Transduction; Substance P

2006
Effect of pituitary adenylate cyclase activating polypeptide-38 on sensory neuropeptide release and neurogenic inflammation in rats and mice.
    Neuroscience, 2006, Nov-17, Volume: 143, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Ear; Electric Stimulation; Hindlimb; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mustard Plant; Neurogenic Inflammation; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Oils; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin; Substance P

2006
[Experimental study on the mechanisms of regulating airway neurogenic inflammation in asthma by never growth factor and leukemia inhibitory factor].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2006, Volume: 29, Issue:6

    Topics: Animals; Asthma; Disease Models, Animal; Ganglia, Spinal; Leukemia Inhibitory Factor; Lung; Male; Nerve Growth Factor; Neurogenic Inflammation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P

2006
Involvement of substance P and neurogenic inflammation in arsenic-induced early vascular dysfunction.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:1

    Topics: Analgesics; Animals; Arsenites; Capillary Permeability; Capsaicin; Ear; Endothelium, Vascular; Environmental Pollutants; Histamine; Histamine H1 Antagonists; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Pyrilamine; Receptors, Neurokinin-1; Skin; Sodium Compounds; Substance P; Time Factors

2007
Specific expression of substance P in synovial tissues of patients with symptomatic, non-reducing internal derangement of the temporomandibular joint: comparison with clinical findings.
    The British journal of oral & maxillofacial surgery, 2007, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthralgia; Case-Control Studies; Endothelium, Vascular; Female; Humans; Immunohistochemistry; Joint Dislocations; Male; Middle Aged; Neurogenic Inflammation; Statistics, Nonparametric; Substance P; Synovial Membrane; Synovitis; Temporomandibular Joint; Temporomandibular Joint Disorders

2007
Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation.
    Neuroscience, 2007, Mar-16, Volume: 145, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Colitis; Colon; Disease Models, Animal; Enteric Nervous System; Ethanol; Inflammation Mediators; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Oligonucleotides, Antisense; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Sympathetic Nervous System; Zymosan

2007
Continuous intra-arterial application of substance P induces signs and symptoms of experimental complex regional pain syndrome (CRPS) such as edema, inflammation and mechanical pain but no thermal pain.
    Neuroscience, 2007, Sep-07, Volume: 148, Issue:3

    Topics: Animals; Chemotaxis, Leukocyte; Complex Regional Pain Syndromes; Disease Models, Animal; Edema; Endothelial Cells; Hyperalgesia; Hypesthesia; Infusion Pumps, Implantable; Injections, Intra-Arterial; Male; Microcirculation; Neurogenic Inflammation; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Substance P

2007
Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:2

    Topics: Animals; CD4 Lymphocyte Count; Cytokines; Dermatitis, Atopic; Female; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nerve Fibers; Neurogenic Inflammation; Receptors, Neurokinin-1; Skin; Stress, Psychological; Substance P; Th2 Cells

2008
Roles of TRPV1 and neuropeptidergic receptors in dorsal root reflex-mediated neurogenic inflammation induced by intradermal injection of capsaicin.
    Molecular pain, 2007, Oct-25, Volume: 3

    Topics: Analgesics; Animals; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Edema; GABA Antagonists; Injections, Intradermal; Neurogenic Inflammation; Peptide Fragments; Rats; Receptors, Neurokinin-1; Reflex; Spinal Nerve Roots; Substance P; TRPV Cation Channels; Vasodilation

2007
Inhibitory action of endomorphin-1 on sensory neuropeptide release and neurogenic inflammation in rats and mice.
    Neuroscience, 2008, Mar-03, Volume: 152, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Male; Mice; Mice, Inbred BALB C; Mustard Plant; Neurogenic Inflammation; Neurons, Afferent; Oligopeptides; Plant Oils; Rats; Rats, Wistar; Skin; Substance P

2008
Experimental tooth pain elevates substance P and matrix metalloproteinase-8 levels in human gingival crevice fluid.
    Acta odontologica Scandinavica, 2008, Volume: 66, Issue:1

    Topics: Adult; Dental Pulp; Electric Stimulation; Female; Fluorescent Antibody Technique; Gingiva; Gingival Crevicular Fluid; Humans; Immunoenzyme Techniques; Incisor; Male; Matrix Metalloproteinase 8; Neurogenic Inflammation; Pain Measurement; Pilot Projects; Statistics, Nonparametric; Substance P; Toothache

2008
Vanilloid receptor TRPV1, sensory C-fibers, and activation of adventitial mast cells. A novel mechanism involved in adventitial inflammation.
    Medical hypotheses, 2008, Volume: 71, Issue:1

    Topics: Animals; Connective Tissue; Humans; Mast Cells; Models, Biological; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Substance P; TRPV Cation Channels

2008
The effects of SDZ NKT 343, a potent NK1 receptor antagonist, on cutaneous responses of primate spinothalamic tract neurones sensitized by intradermal capsaicin injection.
    Experimental brain research, 1998, Volume: 121, Issue:3

    Topics: Action Potentials; Animals; Capsaicin; Electrophysiology; Haplorhini; Injections, Intradermal; Male; Naphthalenes; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Proline; Skin; Spinothalamic Tracts; Substance P

1998
Activity of tachykinin NK1 and bradykinin B2 receptor antagonists, and an opioid ligand at different stimulation parameters in neurogenic inflammation in the rat.
    Neuroscience letters, 1998, Nov-20, Volume: 257, Issue:1

    Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Edema; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extravasation of Diagnostic and Therapeutic Materials; Male; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptide Fragments; Piperidines; Quinuclidines; Rats; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Neurokinin-1; Receptors, Opioid, mu; Substance P; Time Factors

1998
Calcitonin gene-related peptide and prostaglandin E2 but not substance P release induced by antidromic nerve stimulation from rat skin in vitro.
    Neuroscience, 1999, Volume: 89, Issue:1

    Topics: Acetamides; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Dinoprostone; Electric Stimulation; Female; In Vitro Techniques; Male; Membrane Potentials; Nerve Fibers; Neurogenic Inflammation; Nociceptors; Pain; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Skin; Stimulation, Chemical; Substance P; Vasodilation

1999
Methylprednisolone prevents the development of autotomy and neuropathic edema in rats, but has no effect on nociceptive thresholds.
    Pain, 1999, Volume: 80, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Axotomy; Dose-Response Relationship, Drug; Edema; Evans Blue; Glucocorticoids; Hindlimb; Hyperalgesia; Male; Methylprednisolone; Neurogenic Inflammation; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Reflex; Sciatic Nerve; Substance P

1999
Effect of inflammatory stimuli on the silver staining pattern of the rat carotid endothelium.
    The Histochemical journal, 1999, Volume: 31, Issue:3

    Topics: Animals; Capsaicin; Carotid Artery, Common; Cell Adhesion; Endothelium, Vascular; Intercellular Junctions; Leukocytes; Male; Neurogenic Inflammation; Rats; Rats, Wistar; Silver Staining; Substance P

1999
Analysis of the inflammatory response induced by substance P in the mouse pleural cavity.
    Peptides, 1999, Volume: 20, Issue:2

    Topics: Animals; Cell Movement; Chemotaxis, Leukocyte; Exudates and Transudates; Female; Inflammation Mediators; Leukocytes, Mononuclear; Male; Mice; Neurogenic Inflammation; Pleura; Pleurisy; Receptors, Tachykinin; Substance P

1999
Acute immobilization stress triggers skin mast cell degranulation via corticotropin releasing hormone, neurotensin, and substance P: A link to neurogenic skin disorders.
    Brain, behavior, and immunity, 1999, Volume: 13, Issue:3

    Topics: Acute Disease; Animals; Antibodies; Capsaicin; Cell Degranulation; Corticotropin-Releasing Hormone; Male; Mast Cells; Microscopy, Electron; Microtomy; Neurogenic Inflammation; Neuroimmunomodulation; Neuropeptides; Neurotensin; Psoriasis; Pyrazoles; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Restraint, Physical; Skin; Stress, Physiological; Substance P; Urticaria

1999
Effect of nitric oxide on substance P release from the peripheral endings of primary afferent neurons.
    Neuroscience letters, 1999, Aug-27, Volume: 271, Issue:3

    Topics: Animals; Enzyme Inhibitors; Evans Blue; Hot Temperature; Male; Nerve Endings; Neurogenic Inflammation; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Rats; Rats, Sprague-Dawley; Substance P

1999
Modulation of peripheral inflammation by locally administered endomorphin-1.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1999, Volume: 48, Issue:10

    Topics: Administration, Topical; Analgesics, Opioid; Animals; Blister; Blood Flow Velocity; Electric Stimulation; Male; Naloxone; Neurogenic Inflammation; Oligopeptides; Plasma; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sciatic Nerve; Skin Diseases, Vesiculobullous; Substance P; Vasodilation

1999
Carboxypeptidase-mediated metabolism of calcitonin gene-related peptide in human gingival crevicular fluid--a rôle in periodontal inflammation?
    Journal of clinical periodontology, 2000, Volume: 27, Issue:7

    Topics: Adult; Calcitonin Gene-Related Peptide; Carboxypeptidases; Case-Control Studies; Female; Gingival Crevicular Fluid; Humans; Hydrolysis; Male; Neurogenic Inflammation; Neurokinin A; Periodontitis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P

2000
Changes in substance P and neurokinin A in gingival crevicular fluid in response to periodontal treatment.
    Journal of clinical periodontology, 2000, Volume: 27, Issue:7

    Topics: Adult; Aged; Dental Scaling; Female; Gingival Crevicular Fluid; Humans; Male; Middle Aged; Neurogenic Inflammation; Neurokinin A; Periodontal Index; Periodontitis; Radioimmunoassay; Statistics, Nonparametric; Substance P; Tachykinins

2000
The tachykinin NK(1) receptor antagonist SR140333 prevents the increase of nerve growth factor in rat paw skin induced by substance P or neurogenic inflammation.
    Neuroscience, 2000, Volume: 100, Issue:3

    Topics: Animals; Hindlimb; Injections; Male; Nerve Growth Factor; Neurogenic Inflammation; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Tachykinin; Skin; Substance P

2000
Electrically evoked neuropeptide release and neurogenic inflammation differ between rat and human skin.
    The Journal of physiology, 2000, Dec-15, Volume: 529 Pt 3

    Topics: Adult; Animals; Blood Proteins; Calcitonin Gene-Related Peptide; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Neurogenic Inflammation; Neuropeptides; Osmolar Concentration; Plasmapheresis; Rats; Skin; Substance P

2000
Exaggerated neurogenic inflammation and substance P receptor upregulation in RSV-infected weanling rats.
    American journal of respiratory cell and molecular biology, 2001, Volume: 24, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Body Weight; Cell Line; DNA Primers; Humans; Immunoenzyme Techniques; Lung; Neurogenic Inflammation; Neuropeptides; Piperidines; Rats; Rats, Inbred F344; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Vasoactive Intestinal Peptide; Respiratory Syncytial Virus Infections; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Up-Regulation

2001
The effect of unilateral sympathectomy and cavity preparation on peptidergic nerves and immune cells in rat dental pulp.
    Experimental neurology, 2001, Volume: 169, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Cell Count; Dental Cavity Preparation; Dental Pulp; Female; Immunohistochemistry; Nerve Fibers; Nerve Net; Neurogenic Inflammation; Neurons; Neuropeptide Y; Neuropeptides; Rats; Rats, Sprague-Dawley; Substance P; Superior Cervical Ganglion; Sympathectomy; Trigeminal Ganglion

2001
Influence of painful chronic neuropathy on neurogenic inflammation.
    Pain, 2001, Volume: 92, Issue:1-2

    Topics: Administration, Topical; Analgesics; Animals; Capsaicin; Chronic Disease; Coloring Agents; Electric Stimulation; Evans Blue; Hot Temperature; Indoles; Isoindoles; Ligation; Male; Nerve Fibers; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sciatic Nerve; Sciatica; Substance P

2001
The release of leukotriene B4 from human skin in response to substance P: evidence for the functional heterogeneity of human skin mast cells among individuals.
    Clinical and experimental immunology, 2001, Volume: 124, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Dexamethasone; Epidermal Cells; Epidermis; Female; Genetic Variation; Histamine Release; Humans; Leukotriene B4; Male; Mast Cells; Middle Aged; Neurogenic Inflammation; Neutrophil Infiltration; Substance P

2001
The capsaicin VR1 receptor mediates substance P release in toxin A-induced enteritis in rats.
    Peptides, 2001, Volume: 22, Issue:9

    Topics: Acute-Phase Reaction; Animals; Bacterial Toxins; Capsaicin; Clostridioides difficile; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Enteritis; Enterotoxins; Ileum; Immunohistochemistry; Intestinal Secretions; Male; Neurogenic Inflammation; Neurons; Peroxidase; Rats; Receptors, Drug; Substance P; Time Factors

2001
Substance P and mast cells: preliminary histologic analysis of the human temporomandibular joint.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2001, Volume: 92, Issue:4

    Topics: Adult; Arteries; Female; Humans; Immunohistochemistry; Joint Dislocations; Mast Cells; Middle Aged; Neurogenic Inflammation; Substance P; Temporomandibular Joint; Temporomandibular Joint Disorders

2001
Involvement of substance P, mast cells, TNF-alpha and ICAM-1 in the infiltration of inflammatory cells in human periapical granulomas.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2002, Volume: 31, Issue:3

    Topics: Adult; Calcitonin Gene-Related Peptide; Case-Control Studies; Chemotaxis, Leukocyte; Disease Progression; E-Selectin; Endothelium, Vascular; Female; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Male; Mast Cells; Middle Aged; Neurogenic Inflammation; Periapical Granuloma; Substance P; Tumor Necrosis Factor-alpha

2002
Twenty-four hour exposure to prostaglandin downregulates prostanoid receptor binding but does not alter PGE(2)-mediated sensitization of rat sensory neurons.
    Pain, 2002, Volume: 96, Issue:3

    Topics: Animals; Cells, Cultured; Cyclic AMP; Dinoprostone; Down-Regulation; Female; Ganglia, Spinal; Male; Neurogenic Inflammation; Neurons, Afferent; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Spinal Cord; Substance P; Tritium

2002
Comparative immunohistochemical analysis of the peptidergic innervation of human primary and permanent tooth pulp.
    Archives of oral biology, 2002, Volume: 47, Issue:5

    Topics: Analysis of Variance; Calcitonin Gene-Related Peptide; Child; Dental Caries; Dental Pulp; Dentition, Permanent; Disease Progression; Enkephalins; Fluorescent Antibody Technique, Indirect; Galanin; Humans; Molar; Neurogenic Inflammation; Neuropeptide Y; Neuropeptides; Somatostatin; Statistics, Nonparametric; Substance P; Tooth, Deciduous; Vasoactive Intestinal Peptide

2002