Page last updated: 2024-08-23

substance p and Low Back Ache

substance p has been researched along with Low Back Ache in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (29.17)18.2507
2000's6 (25.00)29.6817
2010's6 (25.00)24.3611
2020's5 (20.83)2.80

Authors

AuthorsStudies
Cao, P; Chen, Z; Jiao, Y; Li, J; Lin, Y; Shi, L; Zhang, Y; Zheng, J; Zheng, Y1
Chen, PN; Cui, J; Fu, J; Wang, XZ; Xiao, CH; Xue, KY1
Jin, LY; Li, XF; Luo, Y; Song, XX; Yu, BW1
Chen, J; Huang, B; Li, S; Liu, J; Wei, X; Wu, H; Xiang, Y; Zhao, F1
Chen, Z; Guo, Z; Li, J; Wu, W; Zhang, J; Zhang, X; Zheng, J1
Guo, Z; Li, XF; Shi, S; Song, XX; Yu, BW1
Kamaruddin, K; Lim, SM; Ming, LC; Neoh, CF; Ramasamy, K; Sejari, N1
Badger, GJ; Bishop, JH; Fox, JR; Henry, SM; Langevin, HM; Loretan, C; Maple, R; Vizzard, MA1
Freeman, TA; Isaza, JE; Kurtz, SM; Lanman, TH; Steinbeck, MJ; Veruva, SY1
Brankamp, J; Hanesch, U; Hilken, G; Löer, F; Saxler, G; von Knoch, M1
Doyle, P; Gnanalingham, K; Hoyland, JA; Minogue, BM; Richardson, SM1
Aoki, Y; Eguchi, Y; Endo, M; Inoue, G; Ito, T; Kishida, S; Koshi, T; Nakagawa, K; Ochiai, N; Ohtori, S; Orita, S; Suzuki, M; Takahashi, K; Takaso, M; Yamashita, M; Yamashita, T; Yamauchi, K1
Kikuchi, S; Kobayashi, Y; Konno, S; Sekiguchi, M1
Hoheisel, U; Mense, S; Tesarz, J; Wiedenhöfer, B1
Fu, XB; Hou, SX; Peng, BG; Wang, XH; Wu, WW; Yang, Y; Zhang, CL1
Chen, J; Hou, S; Li, L; Peng, B; Shi, Y; Wu, W; Yang, Y1
Sameshima, K1
Beaman, DN; Chang, V; Glover, RA; Graziano, GP; Wojtys, EM1
Johnson, BW; Kambam, JR; Naukam, RJ; Parris, WC; Sastry, BV1
McLain, RF; Weinstein, JN1
Avramov, A; Cavanaugh, JM; Getchell, TV; King, AI; Ozaktay, AC; Yamashita, T1
Coppes, MH; Groen, GJ; Marani, E; Thomeer, RT1
Hashimoto, S; Imasato, H; Inoue, A; Komori, H; Nagata, K1
Chiba, T; Moriya, H; Ohtori, S; Sameda, H; Takahashi, K; Yamagata, M1

Reviews

1 review(s) available for substance p and Low Back Ache

ArticleYear
Mechanisms of low back pain: a neurophysiologic and neuroanatomic study.
    Clinical orthopaedics and related research, 1997, Issue:335

    Topics: Animals; Intervertebral Disc; Joints; Low Back Pain; Lumbar Vertebrae; Male; Mechanoreceptors; Nerve Endings; Neural Conduction; Neuroanatomy; Neurophysiology; Rabbits; Spinal Nerve Roots; Substance P

1997

Trials

4 trial(s) available for substance p and Low Back Ache

ArticleYear
Ma's bamboo-based medicinal moxibustion therapy of low back pain in lumbar disc herniation: study protocol for a randomized controlled trial.
    Trials, 2022, May-28, Volume: 23, Issue:1

    Topics: Acupuncture Therapy; beta-Endorphin; Humans; Intervertebral Disc Displacement; Low Back Pain; Moxibustion; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sciatica; Substance P

2022
The immediate effect of traditional Malay massage on substance P, inflammatory mediators, pain scale and functional outcome among patients with low back pain: study protocol of a randomised controlled trial.
    BMC complementary and alternative medicine, 2016, Jan-15, Volume: 16

    Topics: Clinical Protocols; Humans; Inflammation Mediators; Low Back Pain; Massage; Outcome Assessment, Health Care; Pain Measurement; Patient Selection; Substance P

2016
[Substance P-like immunoreactivity in cerebrospinal fluid in lumbar disc herniation].
    Nihon Seikeigeka Gakkai zasshi, 1995, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Aged; Female; Humans; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Substance P

1995
Objective evaluation of pain in various spinal diseases: neuropeptide immunoreactivity in the cerebrospinal fluid.
    Spinal cord, 1997, Volume: 35, Issue:11

    Topics: Activities of Daily Living; beta-Endorphin; Humans; Low Back Pain; Neuropeptides; Pain; Pain Measurement; Radioimmunoassay; Spinal Cord Diseases; Substance P

1997

Other Studies

19 other study(ies) available for substance p and Low Back Ache

ArticleYear
Propionibacterium acnes contributes to low back pain via upregulation of NGF in TLR2-NF-κB/JNK or ROS pathway.
    Microbes and infection, 2022, Volume: 24, Issue:6-7

    Topics: Animals; Calcitonin Gene-Related Peptide; Low Back Pain; Nerve Growth Factor; NF-kappa B; Propionibacterium acnes; Rats; Reactive Oxygen Species; Substance P; Toll-Like Receptor 2; Up-Regulation

2022
Substance P Mediates Estrogen Modulation Proinflammatory Cytokines Release in Intervertebral Disc.
    Inflammation, 2021, Volume: 44, Issue:2

    Topics: Animals; Biomarkers; Cytokines; Estrogens; Female; Immunohistochemistry; Inflammation; Intervertebral Disc Degeneration; Low Back Pain; Mice; Mice, Inbred C57BL; Nucleus Pulposus; Random Allocation; Real-Time Polymerase Chain Reaction; Substance P

2021
Damage to the human lumbar cartilage endplate and its clinical implications.
    Journal of anatomy, 2021, Volume: 238, Issue:2

    Topics: Adult; Aged; Case-Control Studies; Female; Humans; Hyaline Cartilage; Intervertebral Disc Degeneration; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Nucleus Pulposus; Substance P

2021
Reactive Oxygen Species Mediate Low Back Pain by Upregulating Substance P in Intervertebral Disc Degeneration.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Adult; Aged; Aged, 80 and over; Animals; Humans; Intervertebral Disc Degeneration; Low Back Pain; Male; Middle Aged; Rats; Reactive Oxygen Species; Substance P; Up-Regulation

2021
Estrogen receptors involvement in intervertebral discogenic pain of the elderly women: colocalization and correlation with the expression of Substance P in nucleus pulposus.
    Oncotarget, 2017, Jun-13, Volume: 8, Issue:24

    Topics: Aged; Female; Humans; Intervertebral Disc Degeneration; Intervertebral Disc Displacement; Low Back Pain; Nucleus Pulposus; Receptors, Estrogen; Substance P

2017
Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Calcitonin Gene-Related Peptide; Fascia; Gait; Low Back Pain; Male; Range of Motion, Articular; Spinal Cord; Substance P; Sus scrofa; Ultrasonography

2016
Periprosthetic UHMWPE Wear Debris Induces Inflammation, Vascularization, and Innervation After Total Disc Replacement in the Lumbar Spine.
    Clinical orthopaedics and related research, 2017, Volume: 475, Issue:5

    Topics: Adult; Biopsy; Cytokines; Device Removal; Discitis; Female; Humans; Immunohistochemistry; Inflammation Mediators; Intervertebral Disc; Intervertebral Disc Degeneration; Low Back Pain; Lumbar Vertebrae; Macrophages; Male; Middle Aged; Neovascularization, Pathologic; Pain Measurement; Pain, Postoperative; Polyethylenes; Prosthesis Design; Reoperation; Risk Factors; Stress, Mechanical; Substance P; Time Factors; Total Disc Replacement; Treatment Outcome; United States; Vascular Endothelial Growth Factor A; Young Adult

2017
The density of nociceptive SP- and CGRP-immunopositive nerve fibers in the dura mater lumbalis of rats is enhanced after laminectomy, even after application of autologous fat grafts.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2008, Volume: 17, Issue:10

    Topics: Adipose Tissue; Animals; Calcitonin Gene-Related Peptide; Dura Mater; Immunohistochemistry; Laminectomy; Low Back Pain; Lumbosacral Region; Male; Nerve Fibers; Nociceptors; Postoperative Complications; Rats; Rats, Inbred Lew; Spinal Cord; Substance P

2008
Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc.
    Arthritis research & therapy, 2009, Volume: 11, Issue:4

    Topics: Gene Expression; Humans; Immunohistochemistry; Interleukin-1; Intervertebral Disc; Low Back Pain; Matrix Metalloproteinase 10; Nerve Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance P; Tumor Necrosis Factor-alpha

2009
Nerve growth factor of cultured medium extracted from human degenerative nucleus pulposus promotes sensory nerve growth and induces substance p in vitro.
    Spine, 2009, Oct-01, Volume: 34, Issue:21

    Topics: Adult; Animals; Animals, Newborn; Antibodies; Axons; Cells, Cultured; Culture Media; Enzyme-Linked Immunosorbent Assay; Ganglia, Spinal; Humans; Immunohistochemistry; In Vitro Techniques; Intervertebral Disc; Low Back Pain; Middle Aged; Nerve Growth Factor; Rats; Rats, Wistar; Recombinant Proteins; Sensory Receptor Cells; Spinal Diseases; Substance P

2009
Increased intramuscular pressure in lumbar paraspinal muscles and low back pain: model development and expression of substance P in the dorsal root ganglion.
    Spine, 2010, Jul-01, Volume: 35, Issue:15

    Topics: Animals; Blood Flow Velocity; Calcitonin Gene-Related Peptide; Disease Models, Animal; Female; Ganglia, Spinal; Laser-Doppler Flowmetry; Low Back Pain; Lumbar Vertebrae; Muscle, Skeletal; Pressure; Rats; Rats, Sprague-Dawley; Substance P

2010
Sensory innervation of the thoracolumbar fascia in rats and humans.
    Neuroscience, 2011, Oct-27, Volume: 194

    Topics: Animals; Back; Calcitonin Gene-Related Peptide; Fascia; Female; Humans; Low Back Pain; Male; Nociceptors; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Substance P

2011
[The pathogenesis of discogenic low back pain].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2004, Jun-22, Volume: 42, Issue:12

    Topics: Adult; Female; Humans; Intervertebral Disc; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Neurofilament Proteins; Substance P; Vasoactive Intestinal Peptide

2004
Effect of the L2 ramus communicans on the nociceptive pathway in lumbar intervertebral discs in rats.
    European journal of pain (London, England), 2008, Volume: 12, Issue:6

    Topics: Afferent Pathways; Animals; Cell Count; Fluorescent Dyes; Ganglia, Spinal; Groin; Intervertebral Disc; Longitudinal Ligaments; Low Back Pain; Lumbar Vertebrae; Male; Neurons, Afferent; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Nerves; Stilbamidines; Substance P; Sympathetic Nervous System

2008
Substance P innervation of lumbar spine facet joints.
    Spine, 1993, Jun-15, Volume: 18, Issue:8

    Topics: Adult; Aged; Female; Humans; Immunoenzyme Techniques; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Nerve Fibers; Substance P

1993
Immunoreactive substance P in human saliva. A possible marker of chronic pain.
    Annals of the New York Academy of Sciences, 1993, Sep-20, Volume: 694

    Topics: Adult; Biomarkers; Blood Proteins; Chronic Disease; Humans; Low Back Pain; Middle Aged; Saliva; Salivary Proteins and Peptides; Substance P

1993
Morphometric model of normal rabbit dorsal root ganglia.
    Spine, 1993, Oct-01, Volume: 18, Issue:13

    Topics: Animals; Ganglia, Spinal; Low Back Pain; Microscopy, Electron; Models, Neurological; Neurons; Pain; Rabbits; Substance P; Vasoactive Intestinal Peptide; Vibration

1993
Innervation of "painful" lumbar discs.
    Spine, 1997, Oct-15, Volume: 22, Issue:20

    Topics: Acetylcholinesterase; Adult; Blood Vessels; DNA-Binding Proteins; Female; Humans; Immunohistochemistry; Intervertebral Disc; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Male; Mechanoreceptors; Middle Aged; Nerve Fibers, Myelinated; NFATC Transcription Factors; Nuclear Proteins; Substance P; Transcription Factors

1997
Substance P and calcitonin gene-related peptide immunoreactive sensory DRG neurons innervating the lumbar facet joints in rats.
    Autonomic neuroscience : basic & clinical, 2000, Dec-28, Volume: 86, Issue:1-2

    Topics: Animals; Calcitonin Gene-Related Peptide; Fluorescent Dyes; Ganglia, Spinal; Ganglia, Sympathetic; Immunohistochemistry; Low Back Pain; Lumbar Vertebrae; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Stilbamidines; Substance P; Zygapophyseal Joint

2000