substance p has been researched along with Lesion of Sciatic Nerve in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (71.43) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Fukushige, R; Hisaoka-Nakashima, K; Kishida, Y; Morioka, N; Nakamura, Y; Nakata, Y; Watanabe, K | 1 |
| Fahmy, A; Hegazy, N; Rezq, S | 1 |
| Chacur, M; da Silva, JT; Evangelista, BG; Seminowicz, DA; Venega, RAG | 1 |
| Chen, YW; Huang, PC; Hung, CH; Shao, DZ; Tzeng, JI; Wang, JJ | 1 |
| Bianchi, R; Caruso, D; Giatti, S; Gotti, S; Melcangi, RC; Panzica, GC; Pesaresi, M; Roglio, I; Scurati, S | 1 |
| Chen, CC; Hsieh, ST; Hsieh, YL; Tseng, TJ | 2 |
| Li, YS; Morioka, N; Nakata, Y; Ogata, N; Shiba, E; Tang, HB; Zheng, TX | 1 |
| Chikuma, T; Kato, T; Muramatsu, M; Takeda, K | 1 |
| Oblinger, MM; Sarajari, S | 1 |
| Corder, G; Intondi, AB; Siegel, A; Taylor, BK; Zadina, JE; Zhang, X | 1 |
| Schött, E; Wallin, J | 1 |
| Kocsis, JD; White, FA | 1 |
| Geenen, F; Kontinen, VK; Meert, TF; Vissers, K | 1 |
| Adler, JE; Skoff, AM; Swamydas, M | 1 |
| Li, J; Sun, YG; Yang, BN; Yu, LC | 1 |
| Hong, JS; Schwasinger, ET; Tseng, LF; Wu, HE | 1 |
| Beaudry, F; Girard, C; Vachon, P | 1 |
| Hama, A; Herzberg, U; Sagen, J | 1 |
| Asensio, E; Casals, L; Navarro, X; Puigdemasa, A; Udina, E; Vivó, M | 1 |
| Hirata, A; Kamakura, K; Masaki, T; Motoyoshi, K | 1 |
21 other study(ies) available for substance p and Lesion of Sciatic Nerve
| Article | Year |
|---|---|
Continuous infusion of substance P into rat striatum relieves mechanical hypersensitivity caused by a partial sciatic nerve ligation via activation of striatal muscarinic receptors.
Topics: Animals; Chronic Pain; Corpus Striatum; Hyperalgesia; Male; Neuralgia; Nociception; Pain Measurement; Peripheral Nerve Injuries; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Neurokinin-1; Sciatic Nerve; Sciatic Neuropathy; Substance P | 2020 |
Renin-angiotensin system blockade modulates both the peripheral and central components of neuropathic pain in rats: Role of calcitonin gene-related peptide, substance P and nitric oxide.
Topics: Analgesics; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Calcitonin Gene-Related Peptide; Disease Models, Animal; Male; Nitric Oxide; Pain Threshold; Rats; Renin-Angiotensin System; Sciatic Nerve; Sciatic Neuropathy; Signal Transduction; Substance P | 2020 |
Anti-NGF treatment can reduce chronic neuropathic pain by changing peripheral mediators and brain activity in rats.
Topics: Animals; Antibodies; Brain; Disease Models, Animal; Ganglia, Spinal; Male; Nerve Growth Factor; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Sciatic Neuropathy; Spinal Cord; Substance P; Time Factors; Up-Regulation | 2019 |
Therapeutic ultrasound suppresses neuropathic pain and upregulation of substance P and neurokinin-1 receptor in rats after peripheral nerve injury.
Topics: Animals; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Sciatic Neuropathy; Substance P; Treatment Outcome; Ultrasonic Therapy; Up-Regulation | 2015 |
Neuroprotective effects of dihydroprogesterone and progesterone in an experimental model of nerve crush injury.
Topics: 20-alpha-Dihydroprogesterone; Animals; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Extracellular Matrix Proteins; Gene Expression Regulation; Locomotion; Male; Molecular Weight; Myelin Proteins; Nerve Tissue Proteins; Neuroprotective Agents; Pain Threshold; Progesterone; Rats; Rats, Sprague-Dawley; Reelin Protein; Sciatic Neuropathy; Serine Endopeptidases; Sodium-Potassium-Exchanging ATPase; Substance P; Time Factors | 2008 |
Influences of surgical decompression on the dorsal horn after chronic constriction injury: changes in peptidergic and delta-opioid receptor (+) nerve terminals.
Topics: Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Decompression, Surgical; Disease Models, Animal; Functional Laterality; Gene Expression Regulation; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, delta; Sciatic Neuropathy; Substance P; Time Factors | 2008 |
Involvement of voltage-gated sodium channel Na(v)1.8 in the regulation of the release and synthesis of substance P in adult mouse dorsal root ganglion neurons.
Topics: Animals; Capsaicin; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Ganglia, Spinal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Potassium Chloride; Protein Precursors; Radioimmunoassay; Receptors, Neurokinin-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sciatic Neuropathy; Sodium Channels; Substance P; Tachykinins | 2008 |
Effect of memantine on the levels of neuropeptides and microglial cells in the brain regions of rats with neuropathic pain.
Topics: Analgesics; Animals; Brain; CD11 Antigens; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hyperalgesia; Hypothalamus; Male; Memantine; Microglia; Neuralgia; Neuropeptides; Periaqueductal Gray; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Sciatic Neuropathy; Somatostatin; Substance P | 2009 |
Estrogen effects on pain sensitivity and neuropeptide expression in rat sensory neurons.
Topics: Animals; Calcitonin Gene-Related Peptide; Cell Count; Down-Regulation; Estrogen Replacement Therapy; Estrogens; Female; Ganglia, Spinal; Hyperalgesia; Immunohistochemistry; In Situ Hybridization; Ovariectomy; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; RNA, Messenger; Sciatic Neuropathy; Sensory Receptor Cells; Substance P | 2010 |
A novel method to quantify histochemical changes throughout the mediolateral axis of the substantia gelatinosa after spared nerve injury: characterization with TRPV1 and substance P.
Topics: Animals; Disease Models, Animal; Histocytochemistry; Image Processing, Computer-Assisted; Male; Peripheral Nervous System Diseases; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Spinal Nerve Roots; Staining and Labeling; Substance P; Substantia Gelatinosa; Synaptic Transmission; Thiamine Monophosphate; TRPV Cation Channels | 2010 |
Substance P release in the spinal dorsal horn following peripheral nerve injury.
Topics: Animals; Axotomy; Male; Microdialysis; Peripheral Nerve Injuries; Physical Stimulation; Posterior Horn Cells; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Substance P | 2002 |
A-fiber sprouting in spinal cord dorsal horn is attenuated by proximal nerve stump encapsulation.
Topics: Animals; Axons; Axotomy; Cell Division; Cholera Toxin; Female; Horseradish Peroxidase; Implants, Experimental; Lectins; Ligation; Nerve Fibers, Myelinated; Nerve Regeneration; Posterior Horn Cells; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy; Silicone Elastomers; Substance P; Time Factors | 2002 |
Functional role of exogenous administration of substance P in chronic constriction injury model of neuropathic pain in gerbils.
Topics: Animals; Constriction, Pathologic; Dose-Response Relationship, Drug; Gerbillinae; Male; Neurokinin-1 Receptor Antagonists; Pain Measurement; Receptors, Neurokinin-1; Sciatic Neuropathy; Substance P | 2003 |
Partial sciatic nerve transection causes redistribution of pain-related peptides and lowers withdrawal threshold.
Topics: Animals; Disease Models, Animal; Female; Ganglia, Spinal; Lumbosacral Region; Neuropeptides; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Somatostatin; Substance P | 2004 |
Antinociceptive effects of galanin in the rat tuberomammillary nucleus and the plasticity of galanin receptor 1 during hyperalgesia.
Topics: Analysis of Variance; Animals; Carrageenan; Dose-Response Relationship, Drug; Functional Laterality; Galanin; Hyperalgesia; Hypothalamic Area, Lateral; Immunohistochemistry; Male; Neuronal Plasticity; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Reaction Time; Receptors, Galanin; Sciatic Neuropathy; Substance P; Time Factors | 2004 |
Pretreatment with antiserum against dynorphin, substance P, or cholecystokinin enhances the morphine-produced anti-allodynia in the sciatic nerve ligated mice.
Topics: Analgesics, Opioid; Animals; Antibodies; Cholecystokinin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Dynorphins; Immune Sera; Injections, Spinal; Ligation; Male; Mice; Morphine; Neuralgia; Peripheral Nervous System Diseases; Sciatic Nerve; Sciatic Neuropathy; Substance P | 2005 |
Effects of decompression on neuropathic pain behaviors and skin reinnervation in chronic constriction injury.
Topics: Animals; Behavior, Animal; Calcitonin Gene-Related Peptide; Decompression, Surgical; Disease Models, Animal; Foot; Functional Laterality; Hyperalgesia; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Skin; Substance P; Time Factors; Ubiquitin Thiolesterase | 2007 |
Early dexamethasone treatment after implantation of a sciatic-nerve cuff decreases the concentration of substance P in the lumbar spinal cord of rats with neuropathic pain.
Topics: Animals; Anti-Inflammatory Agents; Calcitonin; Cholecystokinin; Chromatography, Liquid; Constriction; Dexamethasone; Disease Models, Animal; Male; Mass Spectrometry; Nerve Fibers; Neurotensin; Random Allocation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sciatic Neuropathy; Spinal Cord; Substance P; Time Factors; Treatment Outcome | 2007 |
Spinal subarachnoid adrenal medullary transplants reduce hind paw swelling and peripheral nerve transport following formalin injection in rats.
Topics: Adrenal Medulla; Afferent Pathways; Animals; Axonal Transport; Chromaffin Cells; Disease Models, Animal; GAP-43 Protein; Immunohistochemistry; Inflammation; Ligation; Male; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Substance P | 2008 |
Immediate electrical stimulation enhances regeneration and reinnervation and modulates spinal plastic changes after sciatic nerve injury and repair.
Topics: Animals; Calcitonin Gene-Related Peptide; Disease Models, Animal; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Female; Hyperalgesia; Lectins; Nerve Regeneration; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Reaction Time; Recovery of Function; Reflex; Sciatic Neuropathy; Spinal Cord; Substance P; Time Factors | 2008 |
Intrathecal administration of nerve growth factor delays GAP 43 expression and early phase regeneration of adult rat peripheral nerve.
Topics: Animals; Axons; Cell Size; Dose-Response Relationship, Drug; Functional Laterality; Ganglia, Spinal; GAP-43 Protein; Immunohistochemistry; Male; Microscopy, Electron; Nerve Fibers, Myelinated; Nerve Growth Factor; Nerve Regeneration; Neurons, Afferent; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy; Substance P; Wallerian Degeneration | 2002 |