Page last updated: 2024-08-23

substance p and Joint Pain

substance p has been researched along with Joint Pain in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's12 (57.14)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Heikkilä, HM; Hielm-Björkman, AK; Innes, JF; Laitinen-Vapaavuori, OM1
Arden, NK; Cicuttini, FM; Cooper, C; Dennison, EM; Doherty, M; Hart, DJ; Jones, G; Laslett, LL; Leaverton, P; Maciewicz, RA; Muir, KR; Rampersaud, E; Soni, A; Spector, TD; Valdes, AM; Walsh, DA; Warner, SC; Zhang, W1
Buchcic, P; Grzegorzewski, A; Jóźwiak, M; Masłoń, A; Modrzewski, T; Pawlak, M1
Chen, J; Li, Z; Liu, Y; Wang, B; Wang, X; Xiao, J; Yu, W1
Brismée, JM; Dedrick, GS; Sawyer, BG; Sizer, PS; Smith, MP1
Kaneyama, K; Miyamaru, M; Nishimura, M; Segami, N; Suzuki, T1
Liu, HX1
Gentle, MJ; Lunam, CA1
Roselló-Sastre, E; Sanchis-Alfonso, V1
Brain, SD; Keeble, JE1
Ordeberg, G1
Bohnsack, M; Hurschler, C; Meier, F; Rühmann, O; Schmolke, S; Walter, GF; Wirth, CJ1
Muneta, T; Sekiya, I; Yagishita, K; Zhang, B1
Brama, PA; Brommer, H; de Grauw, JC; van de Lest, CH; van Weeren, R1
Fujimura, K; Kaneyama, K; Kitagawa, Y; Sato, J; Segami, N; Yoshimura, H; Yoshitake, Y1
Balzarini, P; Bianchi, M; Broggini, M; Franchi, S; Sacerdote, P1
Freudenberger, U; Neugebauer, V; Schaible, HG; Weiretter, F1
Fujita, S; Iizuka, T; Nishida, M; Yoshida, H1
Wagrowska-Danielewicz, M; Witoński, D1
Witonski, D1
Creamer, P1

Reviews

3 review(s) available for substance p and Joint Pain

ArticleYear
A role for substance P in arthritis?
    Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3

    Topics: Animals; Arthralgia; Arthritis; Humans; Joints; Neurokinin-1 Receptor Antagonists; Posterior Horn Cells; Receptors, Neurokinin-1; Sensory Receptor Cells; Substance P; Synovial Membrane

2004
Characterization of joint pain in human OA.
    Novartis Foundation symposium, 2004, Volume: 260

    Topics: Arthralgia; Humans; Hyperalgesia; Nociceptors; Osteoarthritis; Pain Threshold; Peripheral Nervous System Diseases; Substance P

2004
Osteoarthritis pain and its treatment.
    Current opinion in rheumatology, 2000, Volume: 12, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthroplasty, Replacement; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Exercise Therapy; Glucosamine; Humans; Isoenzymes; Membrane Proteins; Nitric Oxide; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Substance P

2000

Trials

2 trial(s) available for substance p and Joint Pain

ArticleYear
The effect of intra-articular botulinum toxin A on substance P, prostaglandin E
    BMC veterinary research, 2017, Mar-21, Volume: 13, Issue:1

    Topics: Animals; Arthralgia; Botulinum Toxins, Type A; Dinoprostone; Dog Diseases; Dogs; Double-Blind Method; Female; Injections, Intra-Articular; Male; Osteoarthritis; Pain; Pain Management; Substance P; Synovial Fluid; Treatment Outcome; Tumor Necrosis Factor-alpha

2017
Effects of nimesulide on pain and on synovial fluid concentrations of substance P, interleukin-6 and interleukin-8 in patients with knee osteoarthritis: comparison with celecoxib.
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Celecoxib; Double-Blind Method; Female; Humans; Interleukin-6; Interleukin-8; Male; Osteoarthritis, Knee; Pain Measurement; Pyrazoles; Substance P; Sulfonamides; Synovial Fluid; Treatment Outcome

2007

Other Studies

16 other study(ies) available for substance p and Joint Pain

ArticleYear
Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene.
    European journal of pain (London, England), 2017, Volume: 21, Issue:7

    Topics: Animals; Arthralgia; Cohort Studies; Female; Genetic Variation; Genotype; Humans; Osteoarthritis, Knee; Pain; Phenotype; Polymorphism, Single Nucleotide; Receptors, Neurokinin-1; Substance P

2017
Hip joint pain in children with cerebral palsy and developmental dysplasia of the hip: why are the differences so huge?
    BMC musculoskeletal disorders, 2014, Mar-21, Volume: 15

    Topics: Adolescent; Age Factors; Arthralgia; Biomarkers; Cerebral Palsy; Child; Child, Preschool; Female; Hip Dislocation; Hip Dislocation, Congenital; Hip Joint; Humans; Immunohistochemistry; Male; Nociception; Nociceptors; Orthopedic Procedures; Pain Measurement; S100 Proteins; Substance P

2014
Correlation between neuropeptide distribution, cancellous bone microstructure and joint pain in postmenopausal women with osteoarthritis and osteoporosis.
    Neuropeptides, 2016, Volume: 56

    Topics: Aged; Arthralgia; Calcitonin Gene-Related Peptide; Cancellous Bone; Female; Humans; Middle Aged; Neuropeptide Y; Neuropeptides; Osteoarthritis; Osteoporosis, Postmenopausal; Pain Measurement; Pain Perception; Postmenopause; Substance P; Vasoactive Intestinal Peptide

2016
Immunohistochemical and histological study of human uncovertebral joints: a preliminary investigation.
    Spine, 2009, May-20, Volume: 34, Issue:12

    Topics: Aged, 80 and over; Arthralgia; Autonomic Pathways; Cadaver; Calcitonin Gene-Related Peptide; Cervical Vertebrae; Chondrocytes; Humans; Immunohistochemistry; Intervertebral Disc; Joint Capsule; Joints; Male; Neck Pain; Neuropeptide Y; Nociceptors; Sensory Receptor Cells; Substance P; Synovial Membrane; Ubiquitin Thiolesterase

2009
Relationships between pain-related mediators and both synovitis and joint pain in patients with internal derangements and osteoarthritis of the temporomandibular joint.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 94, Issue:3

    Topics: Adolescent; Adult; Aged; Arthralgia; Bradykinin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Facial Pain; Female; Humans; Inflammation Mediators; Joint Dislocations; Leukotriene B4; Male; Middle Aged; Neurotransmitter Agents; Nociceptors; Osteoarthritis; Serotonin; Statistics, Nonparametric; Substance P; Synovial Fluid; Synovitis; Temporomandibular Joint Disorders

2002
[Repeated 100 Hz TENS for the treatment of chronic inflammatory pain in rats: optimal parameters and possible neuro-chemical mechanisms].
    Sheng li ke xue jin zhan [Progress in physiology], 1999, Volume: 30, Issue:1

    Topics: Animals; Arthralgia; Arthritis, Experimental; Chronic Disease; Dynorphins; Naltrexone; Pain Threshold; Rats; Substance P; Transcutaneous Electric Nerve Stimulation

1999
Substance P immunoreactive nerve fibres in the domestic chick ankle joint before and after acute urate arthritis.
    Neuroscience letters, 2004, Jan-09, Volume: 354, Issue:2

    Topics: Animals; Arthralgia; Arthritis; Chickens; Disease Models, Animal; Down-Regulation; Female; Gout; Immunohistochemistry; Male; Nerve Fibers; Nociceptors; Sensory Receptor Cells; Substance P; Synovial Membrane; Tarsal Joints; Uric Acid

2004
Anterior knee pain in the young patient--what causes the pain? "Neural model".
    Acta orthopaedica Scandinavica, 2003, Volume: 74, Issue:6

    Topics: Arthralgia; Humans; Ischemia; Knee Joint; Nerve Fibers; Substance P

2003
Distribution of substance-P nerves inside the infrapatellar fat pad and the adjacent synovial tissue: a neurohistological approach to anterior knee pain syndrome.
    Archives of orthopaedic and trauma surgery, 2005, Volume: 125, Issue:9

    Topics: Aged; Aged, 80 and over; Arthralgia; Female; Humans; Immunohistochemistry; Knee Joint; Male; Middle Aged; S100 Proteins; Substance P; Syndrome; Synovial Membrane

2005
Substance P immunoreactive fibers of synovial tissue in patients with anterior cruciate ligament injury.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2006, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Arthralgia; Biomarkers; Female; Humans; Immunohistochemistry; Knee Injuries; Knee Joint; Male; Nerve Fibers; Pain Measurement; Sex Factors; Substance P; Synovial Membrane

2006
Arthrogenic lameness of the fetlock: synovial fluid markers of inflammation and cartilage turnover in relation to clinical joint pain.
    Equine veterinary journal, 2006, Volume: 38, Issue:4

    Topics: Animals; Arthralgia; Biomarkers; Bone and Bones; Cartilage; Case-Control Studies; Dinoprost; Female; Horse Diseases; Horses; Lameness, Animal; Male; Nerve Block; Substance P; Synovial Fluid; Tarsal Joints

2006
Specific expression of substance P in synovial tissues of patients with symptomatic, non-reducing internal derangement of the temporomandibular joint: comparison with clinical findings.
    The British journal of oral & maxillofacial surgery, 2007, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthralgia; Case-Control Studies; Endothelium, Vascular; Female; Humans; Immunohistochemistry; Joint Dislocations; Male; Middle Aged; Neurogenic Inflammation; Statistics, Nonparametric; Substance P; Synovial Membrane; Synovitis; Temporomandibular Joint; Temporomandibular Joint Disorders

2007
The involvement of substance P and neurokinin-1 receptors in the responses of rat dorsal horn neurons to noxious but not to innocuous mechanical stimuli applied to the knee joint.
    Brain research, 1994, Dec-15, Volume: 666, Issue:2

    Topics: Animals; Arthralgia; Biphenyl Compounds; Immunologic Techniques; Knee Joint; Male; Neural Pathways; Neurokinin-1 Receptor Antagonists; Neurons; Physical Stimulation; Rats; Rats, Wistar; Receptors, Neurokinin-1; Spinal Cord; Substance P

1994
The expression of substance P in human temporomandibular joint samples: an immunohistochemical study.
    Journal of oral rehabilitation, 1999, Volume: 26, Issue:4

    Topics: Adult; Aged; Arthralgia; Female; Humans; Immunoenzyme Techniques; Joint Dislocations; Male; Middle Aged; Substance P; Synovial Membrane; Synovitis; Temporomandibular Joint; Temporomandibular Joint Disc; Temporomandibular Joint Disorders

1999
Distribution of substance-P nerve fibers in the knee joint in patients with anterior knee pain syndrome. A preliminary report.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 1999, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Arthralgia; Female; Humans; Immunohistochemistry; Knee Joint; Male; Nerve Fibers; Substance P

1999
Anterior knee pain syndrome.
    International orthopaedics, 1999, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Arthralgia; Depression; Female; Humans; Joint Instability; Knee Joint; Male; Middle Aged; Personality Inventory; Range of Motion, Articular; Substance P

1999